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MX2009006333A - Anticuerpos contra el receptor del factor de crecimiento similar a la insulina i y uso de los mismos. - Google Patents

Anticuerpos contra el receptor del factor de crecimiento similar a la insulina i y uso de los mismos.

Info

Publication number
MX2009006333A
MX2009006333A MX2009006333A MX2009006333A MX2009006333A MX 2009006333 A MX2009006333 A MX 2009006333A MX 2009006333 A MX2009006333 A MX 2009006333A MX 2009006333 A MX2009006333 A MX 2009006333A MX 2009006333 A MX2009006333 A MX 2009006333A
Authority
MX
Mexico
Prior art keywords
receptor
growth factor
antibodies against
against insulin
sugar chain
Prior art date
Application number
MX2009006333A
Other languages
English (en)
Inventor
Klaus-Peter Kuenkele
Hans Koll
Samuel Moser
Sylke Poehling
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX2009006333A publication Critical patent/MX2009006333A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/71—Decreased effector function due to an Fc-modification

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Anticuerpo que se une al IGE-IR y que está glicosilado con una cadena de azúcares en la Asn297, y tal anticuerpo caracterizado porque la cantidad de fucosa dentro de tal cadena de azúcares está entre un 20% y 50%, presenta propiedades mejoradas en la terapia antitumoral.
MX2009006333A 2006-12-22 2007-12-19 Anticuerpos contra el receptor del factor de crecimiento similar a la insulina i y uso de los mismos. MX2009006333A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06026651 2006-12-22
PCT/EP2007/011159 WO2008077546A1 (en) 2006-12-22 2007-12-19 Antibodies against insulin-like growth factor i receptor and uses thereof

Publications (1)

Publication Number Publication Date
MX2009006333A true MX2009006333A (es) 2009-06-23

Family

ID=37989161

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009006333A MX2009006333A (es) 2006-12-22 2007-12-19 Anticuerpos contra el receptor del factor de crecimiento similar a la insulina i y uso de los mismos.

Country Status (21)

Country Link
US (2) US20080226635A1 (es)
EP (1) EP2102242A1 (es)
JP (1) JP2010513352A (es)
KR (2) KR20090088911A (es)
CN (1) CN101611059A (es)
AR (1) AR064620A1 (es)
AU (1) AU2007338402A1 (es)
BR (1) BRPI0722062A2 (es)
CA (1) CA2672715A1 (es)
CL (1) CL2007003726A1 (es)
CR (1) CR10810A (es)
EC (1) ECSP099440A (es)
IL (1) IL198778A0 (es)
MA (1) MA31066B1 (es)
MX (1) MX2009006333A (es)
NZ (1) NZ576956A (es)
PE (1) PE20081832A1 (es)
RU (1) RU2009127846A (es)
TW (1) TW200833712A (es)
WO (1) WO2008077546A1 (es)
ZA (1) ZA200904324B (es)

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