|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4737456A
(en)
|
1985-05-09 |
1988-04-12 |
Syntex (U.S.A.) Inc. |
Reducing interference in ligand-receptor binding assays
|
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
|
US6548640B1
(en)
|
1986-03-27 |
2003-04-15 |
Btg International Limited |
Altered antibodies
|
|
IL85035A0
(en)
|
1987-01-08 |
1988-06-30 |
Int Genetic Eng |
Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
|
|
WO1988007089A1
(en)
|
1987-03-18 |
1988-09-22 |
Medical Research Council |
Altered antibodies
|
|
US5770701A
(en)
|
1987-10-30 |
1998-06-23 |
American Cyanamid Company |
Process for preparing targeted forms of methyltrithio antitumor agents
|
|
US5606040A
(en)
|
1987-10-30 |
1997-02-25 |
American Cyanamid Company |
Antitumor and antibacterial substituted disulfide derivatives prepared from compounds possessing a methyl-trithio group
|
|
US5670373A
(en)
|
1988-01-22 |
1997-09-23 |
Kishimoto; Tadamitsu |
Antibody to human interleukin-6 receptor
|
|
US5126250A
(en)
|
1988-09-28 |
1992-06-30 |
Eli Lilly And Company |
Method for the reduction of heterogeneity of monoclonal antibodies
|
|
WO1990005144A1
(en)
|
1988-11-11 |
1990-05-17 |
Medical Research Council |
Single domain ligands, receptors comprising said ligands, methods for their production, and use of said ligands and receptors
|
|
DE3920358A1
(en)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
BISPECIFIC AND OLIGO-SPECIFIC, MONO- AND OLIGOVALENT ANTI-BODY CONSTRUCTS, THEIR PRODUCTION AND USE
|
|
CA2026147C
(en)
|
1989-10-25 |
2006-02-07 |
Ravi J. Chari |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
US5959177A
(en)
|
1989-10-27 |
1999-09-28 |
The Scripps Research Institute |
Transgenic plants expressing assembled secretory antibodies
|
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
DE69129154T2
(en)
|
1990-12-03 |
1998-08-20 |
Genentech, Inc., South San Francisco, Calif. |
METHOD FOR ENRICHING PROTEIN VARIANTS WITH CHANGED BINDING PROPERTIES
|
|
US5571894A
(en)
|
1991-02-05 |
1996-11-05 |
Ciba-Geigy Corporation |
Recombinant antibodies specific for a growth factor receptor
|
|
JP3370324B2
(en)
|
1991-04-25 |
2003-01-27 |
中外製薬株式会社 |
Reshaped human antibodies to human interleukin-6 receptor
|
|
JP4124480B2
(en)
|
1991-06-14 |
2008-07-23 |
ジェネンテック・インコーポレーテッド |
Immunoglobulin variants
|
|
GB9114948D0
(en)
|
1991-07-11 |
1991-08-28 |
Pfizer Ltd |
Process for preparing sertraline intermediates
|
|
US6136310A
(en)
|
1991-07-25 |
2000-10-24 |
Idec Pharmaceuticals Corporation |
Recombinant anti-CD4 antibodies for human therapy
|
|
WO1993006217A1
(en)
|
1991-09-19 |
1993-04-01 |
Genentech, Inc. |
EXPRESSION IN E. COLI OF ANTIBODY FRAGMENTS HAVING AT LEAST A CYSTEINE PRESENT AS A FREE THIOL, USE FOR THE PRODUCTION OF BIFUNCTIONAL F(ab')2 ANTIBODIES
|
|
FI941572L
(en)
|
1991-10-07 |
1994-05-27 |
Oncologix Inc |
Combination and method of use of anti-erbB-2 monoclonal antibodies
|
|
WO1993008829A1
(en)
|
1991-11-04 |
1993-05-13 |
The Regents Of The University Of California |
Compositions that mediate killing of hiv-infected cells
|
|
ATE503496T1
(en)
|
1992-02-06 |
2011-04-15 |
Novartis Vaccines & Diagnostic |
BIOSYNTHETIC BINDING PROTEIN FOR TUMOR MARKERS
|
|
ATE139900T1
(en)
|
1992-11-13 |
1996-07-15 |
Idec Pharma Corp |
THERAPEUTIC USE OF CHIMERIC AND LABELED ANTIBODIES AGAINST HUMAN B LYMPHOCYTE RESTRICTED DIFFERENTIATION ANTIGEN FOR THE TREATMENT OF B CELL LYMPHOMA
|
|
US5635483A
(en)
|
1992-12-03 |
1997-06-03 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Tumor inhibiting tetrapeptide bearing modified phenethyl amides
|
|
US5780588A
(en)
|
1993-01-26 |
1998-07-14 |
Arizona Board Of Regents |
Elucidation and synthesis of selected pentapeptides
|
|
CA2163345A1
(en)
|
1993-06-16 |
1994-12-22 |
Susan Adrienne Morgan |
Antibodies
|
|
US5773001A
(en)
|
1994-06-03 |
1998-06-30 |
American Cyanamid Company |
Conjugates of methyltrithio antitumor agents and intermediates for their synthesis
|
|
US8017121B2
(en)
|
1994-06-30 |
2011-09-13 |
Chugai Seiyaku Kabushika Kaisha |
Chronic rheumatoid arthritis therapy containing IL-6 antagonist as effective component
|
|
KR100261941B1
(en)
|
1994-07-13 |
2000-07-15 |
나가야마 오사무 |
Reconstituted human antibody against human interleukin-8
|
|
TW416960B
(en)
|
1994-07-13 |
2001-01-01 |
Chugai Pharmaceutical Co Ltd |
Reshaped human antibody to human interleukin-8
|
|
CN1156460A
(en)
|
1994-07-13 |
1997-08-06 |
中外制药株式会社 |
Reconstituted human antibody against human interleukin-8
|
|
JP3865418B2
(en)
|
1994-07-13 |
2007-01-10 |
中外製薬株式会社 |
Reconstituted human antibody against human interleukin-8
|
|
US6048972A
(en)
|
1994-07-13 |
2000-04-11 |
Chugai Pharmaceutical Co., Ltd. |
Recombinant materials for producing humanized anti-IL-8 antibodies
|
|
CZ296979B6
(en)
|
1994-10-21 |
2006-08-16 |
Chugai Seiyaku Kabushiki Kaisha |
Pharmaceutical composition for prevention or treatment of Castleman's disease
|
|
US5789199A
(en)
|
1994-11-03 |
1998-08-04 |
Genentech, Inc. |
Process for bacterial production of polypeptides
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
US5840523A
(en)
|
1995-03-01 |
1998-11-24 |
Genetech, Inc. |
Methods and compositions for secretion of heterologous polypeptides
|
|
US5869046A
(en)
|
1995-04-14 |
1999-02-09 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
|
US5714586A
(en)
|
1995-06-07 |
1998-02-03 |
American Cyanamid Company |
Methods for the preparation of monomeric calicheamicin derivative/carrier conjugates
|
|
US5712374A
(en)
|
1995-06-07 |
1998-01-27 |
American Cyanamid Company |
Method for the preparation of substantiallly monomeric calicheamicin derivative/carrier conjugates
|
|
US6267958B1
(en)
|
1995-07-27 |
2001-07-31 |
Genentech, Inc. |
Protein formulation
|
|
GB9603256D0
(en)
|
1996-02-16 |
1996-04-17 |
Wellcome Found |
Antibodies
|
|
DE69738522T2
(en)
|
1996-08-02 |
2009-04-02 |
Bristol-Myers Squibb Co. |
A METHOD FOR INHIBITING IMMUNOGLOBINENE IN IMMUNOGLOBINS IN THERAPY AND IN VIVO DIAGNOSTIC IMMUNOGLOBININE-INDUCED TOXICITY
|
|
US6025158A
(en)
|
1997-02-21 |
2000-02-15 |
Genentech, Inc. |
Nucleic acids encoding humanized anti-IL-8 monoclonal antibodies
|
|
US6171586B1
(en)
|
1997-06-13 |
2001-01-09 |
Genentech, Inc. |
Antibody formulation
|
|
CN1068524C
(en)
|
1997-06-23 |
2001-07-18 |
叶庆炜 |
Process for preparing medicine for curing intractable psoriasis
|
|
ES2244066T3
(en)
|
1997-06-24 |
2005-12-01 |
Genentech, Inc. |
PROCEDURE AND COMPOSITIONS OF GALACTOSILATED GLICOPROTEINS.
|
|
US6040498A
(en)
|
1998-08-11 |
2000-03-21 |
North Caroline State University |
Genetically engineered duckweed
|
|
US20020187150A1
(en)
|
1997-08-15 |
2002-12-12 |
Chugai Seiyaku Kabushiki Kaisha |
Preventive and/or therapeutic agent for systemic lupus erythematosus comprising anti-IL-6 receptor antibody as an active ingredient
|
|
WO1999022764A1
(en)
|
1997-10-31 |
1999-05-14 |
Genentech, Inc. |
Methods and compositions comprising glycoprotein glycoforms
|
|
US6610833B1
(en)
|
1997-11-24 |
2003-08-26 |
The Institute For Human Genetics And Biochemistry |
Monoclonal human natural antibodies
|
|
WO1999029888A1
(en)
|
1997-12-05 |
1999-06-17 |
The Scripps Research Institute |
Humanization of murine antibody
|
|
US6458355B1
(en)
|
1998-01-22 |
2002-10-01 |
Genentech, Inc. |
Methods of treating inflammatory disease with anti-IL-8 antibody fragment-polymer conjugates
|
|
ES2299241T3
(en)
|
1998-03-17 |
2008-05-16 |
Chugai Seiyaku Kabushiki Kaisha |
PREVENTIVES OR REMEDIES FOR INFLAMMATORY INTESTINAL DISEASES CONTAINING ANTAGONIST ANTIBODIES OF THE IL-6 RECEIVER.
|
|
US6194551B1
(en)
|
1998-04-02 |
2001-02-27 |
Genentech, Inc. |
Polypeptide variants
|
|
ATE375365T1
(en)
|
1998-04-02 |
2007-10-15 |
Genentech Inc |
ANTIBODIES VARIANTS AND FRAGMENTS THEREOF
|
|
PT1071700E
(en)
|
1998-04-20 |
2010-04-23 |
Glycart Biotechnology Ag |
Glycosylation engineering of antibodies for improving antibody-dependent cellular cytotoxicity
|
|
GB9809951D0
(en)
|
1998-05-08 |
1998-07-08 |
Univ Cambridge Tech |
Binding molecules
|
|
EP1141024B1
(en)
|
1999-01-15 |
2018-08-08 |
Genentech, Inc. |
POLYPEPTIDE COMPRISING A VARIANT HUMAN IgG1 Fc REGION
|
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
AU2006225302B2
(en)
|
1999-03-25 |
2010-08-12 |
AbbVie Deutschland GmbH & Co. KG |
Human antibodies that bind human IL-12 and methods for producing
|
|
ES2601882T5
(en)
|
1999-04-09 |
2021-06-07 |
Kyowa Kirin Co Ltd |
Procedure to monitor the activity of an immunofunctional molecule
|
|
SK782002A3
(en)
|
1999-07-21 |
2003-08-05 |
Lexigen Pharm Corp |
FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens
|
|
KR100797667B1
(en)
|
1999-10-04 |
2008-01-23 |
메디카고 인코포레이티드 |
How to regulate transcription of foreign genes
|
|
US7125978B1
(en)
|
1999-10-04 |
2006-10-24 |
Medicago Inc. |
Promoter for regulating expression of foreign genes
|
|
CA2388245C
(en)
|
1999-10-19 |
2012-01-10 |
Tatsuya Ogawa |
The use of serum-free adapted rat cells for producing heterologous polypeptides
|
|
AU784983B2
(en)
|
1999-12-15 |
2006-08-17 |
Genentech Inc. |
Shotgun scanning, a combinatorial method for mapping functional protein epitopes
|
|
DK1242438T3
(en)
|
1999-12-29 |
2007-02-12 |
Immunogen Inc |
Cytotoxic agents comprising modified doxorubicins and daunorubicins and their therapeutic use
|
|
DK2857516T3
(en)
|
2000-04-11 |
2017-08-07 |
Genentech Inc |
Multivalent antibodies and uses thereof
|
|
HU231090B1
(en)
|
2000-10-06 |
2020-07-28 |
Kyowa Kirin Co., Ltd. |
Cells producing antibody compositions
|
|
US6946292B2
(en)
|
2000-10-06 |
2005-09-20 |
Kyowa Hakko Kogyo Co., Ltd. |
Cells producing antibody compositions with increased antibody dependent cytotoxic activity
|
|
US7064191B2
(en)
|
2000-10-06 |
2006-06-20 |
Kyowa Hakko Kogyo Co., Ltd. |
Process for purifying antibody
|
|
AU2000279625A1
(en)
|
2000-10-27 |
2002-05-15 |
Chugai Seiyaku Kabushiki Kaisha |
Blood mmp-3 level-lowering agent containing il-6 antgonist as the active ingredient
|
|
US6596541B2
(en)
|
2000-10-31 |
2003-07-22 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying eukaryotic cells
|
|
EP1916303B1
(en)
|
2000-11-30 |
2013-02-27 |
Medarex, Inc. |
Nucleic acids encoding rearranged human immunoglobulin sequences from transgenic transchromosomal mice
|
|
EP1355919B1
(en)
|
2000-12-12 |
2010-11-24 |
MedImmune, LLC |
Molecules with extended half-lives, compositions and uses thereof
|
|
BR0207854A
(en)
|
2001-03-07 |
2004-08-24 |
Merck Patent Gmbh |
Expression technology for proteins containing a hybrid isotype antibody moiety
|
|
UA80091C2
(en)
|
2001-04-02 |
2007-08-27 |
Chugai Pharmaceutical Co Ltd |
Remedies for infant chronic arthritis-relating diseases and still's disease which contain an interleukin-6 (il-6) antagonist
|
|
UA83791C2
(en)
|
2001-04-13 |
2008-08-26 |
Байоджен Айдек Ма Инк. |
Antibody to vla-1, pharmaceutical composition, containing thereof, and use of them for treatment individual having immunological disorder, mediated by vla-1
|
|
EP1423510A4
(en)
|
2001-08-03 |
2005-06-01 |
Glycart Biotechnology Ag |
ANTIBODY GLYCOSYLATION VARIANTS WITH INCREASED CELL CYTOTOXICITY DEPENDENT OF ANTIBODIES
|
|
HUP0600342A3
(en)
|
2001-10-25 |
2011-03-28 |
Genentech Inc |
Glycoprotein compositions
|
|
CA2467633C
(en)
|
2001-12-03 |
2012-03-27 |
Abgenix, Inc. |
Antibody categorization based on binding characteristics
|
|
US20040093621A1
(en)
|
2001-12-25 |
2004-05-13 |
Kyowa Hakko Kogyo Co., Ltd |
Antibody composition which specifically binds to CD20
|
|
US20070122406A1
(en)
|
2005-07-08 |
2007-05-31 |
Xencor, Inc. |
Optimized proteins that target Ep-CAM
|
|
AU2003217912A1
(en)
|
2002-03-01 |
2003-09-16 |
Xencor |
Antibody optimization
|
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
|
US20050031613A1
(en)
|
2002-04-09 |
2005-02-10 |
Kazuyasu Nakamura |
Therapeutic agent for patients having human FcgammaRIIIa
|
|
WO2003085119A1
(en)
|
2002-04-09 |
2003-10-16 |
Kyowa Hakko Kogyo Co., Ltd. |
METHOD OF ENHANCING ACTIVITY OF ANTIBODY COMPOSITION OF BINDING TO FcϜ RECEPTOR IIIa
|
|
WO2003084569A1
(en)
|
2002-04-09 |
2003-10-16 |
Kyowa Hakko Kogyo Co., Ltd. |
Drug containing antibody composition
|
|
CN102911987B
(en)
|
2002-04-09 |
2015-09-30 |
协和发酵麒麟株式会社 |
The adorned cell of genome
|
|
CA2481656A1
(en)
|
2002-04-09 |
2003-10-16 |
Kyowa Hakko Kogyo Co., Ltd. |
Cells in which activity of the protein involved in transportation of gdp-fucose is reduced or lost
|
|
CA2481837A1
(en)
|
2002-04-09 |
2003-10-16 |
Kyowa Hakko Kogyo Co., Ltd. |
Production process for antibody composition
|
|
US20040018573A1
(en)
|
2002-04-18 |
2004-01-29 |
Power Scott D |
Production of functional antibodies in filamentous fungi
|
|
EP1509770B1
(en)
|
2002-05-31 |
2014-07-09 |
GE Healthcare Bio-Sciences AB |
Method of coupling binding agents to a substrate surface
|
|
CA2488441C
(en)
|
2002-06-03 |
2015-01-27 |
Genentech, Inc. |
Synthetic antibody phage libraries
|
|
WO2004029207A2
(en)
|
2002-09-27 |
2004-04-08 |
Xencor Inc. |
Optimized fc variants and methods for their generation
|
|
ATE480562T1
(en)
|
2002-10-15 |
2010-09-15 |
Facet Biotech Corp |
CHANGE IN FCRN BINDING AFFINITIES OR SERUM HALF-LIFE TIMES OF ANTIBODIES USING MUtagenesis
|
|
US7217797B2
(en)
|
2002-10-15 |
2007-05-15 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
US7361740B2
(en)
|
2002-10-15 |
2008-04-22 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
JP4739763B2
(en)
|
2002-12-16 |
2011-08-03 |
ゲンマブ エー/エス |
Human monoclonal antibody against interleukin 8 (IL-8)
|
|
DK2289936T3
(en)
|
2002-12-16 |
2017-07-31 |
Genentech Inc |
IMMUNGLOBULIN VARIATIONS AND APPLICATIONS THEREOF
|
|
EP3539569A1
(en)
|
2002-12-24 |
2019-09-18 |
Rinat Neuroscience Corp. |
Anti-ngf antibodies and methods using the same in treating pain associated with musculo-skeletal disorders
|
|
EP1585767A2
(en)
|
2003-01-16 |
2005-10-19 |
Genentech, Inc. |
Synthetic antibody phage libraries
|
|
US7871607B2
(en)
|
2003-03-05 |
2011-01-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
|
|
US20060104968A1
(en)
|
2003-03-05 |
2006-05-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
|
|
GB2401040A
(en)
|
2003-04-28 |
2004-11-03 |
Chugai Pharmaceutical Co Ltd |
Method for treating interleukin-6 related diseases
|
|
WO2004113387A2
(en)
|
2003-06-24 |
2004-12-29 |
Merck Patent Gmbh |
Tumour necrosis factor receptor molecules with reduced immunogenicity
|
|
US20050033029A1
(en)
|
2003-06-30 |
2005-02-10 |
Jin Lu |
Engineered anti-target immunoglobulin derived proteins, compositions, methods and uses
|
|
WO2005035586A1
(en)
|
2003-10-08 |
2005-04-21 |
Kyowa Hakko Kogyo Co., Ltd. |
Fused protein composition
|
|
WO2005035778A1
(en)
|
2003-10-09 |
2005-04-21 |
Kyowa Hakko Kogyo Co., Ltd. |
PROCESS FOR PRODUCING ANTIBODY COMPOSITION BY USING RNA INHIBITING THE FUNCTION OF α1,6-FUCOSYLTRANSFERASE
|
|
EP1673395A1
(en)
|
2003-10-15 |
2006-06-28 |
PDL BioPharma, Inc. |
Alteration of fc-fusion protein serum half-lives by mutagenesis of positions 250, 314 and/or 428 of the heavy chain constant region of ig
|
|
DK2380910T3
(en)
|
2003-11-05 |
2015-10-19 |
Roche Glycart Ag |
Antigen binding molecules with increased Fc receptor binding affinity and effector function
|
|
PT2489364E
(en)
|
2003-11-06 |
2015-04-16 |
Seattle Genetics Inc |
Monomethylvaline compounds conjugated to antibodies
|
|
US20050100965A1
(en)
|
2003-11-12 |
2005-05-12 |
Tariq Ghayur |
IL-18 binding proteins
|
|
CA2545603A1
(en)
|
2003-11-12 |
2005-05-26 |
Biogen Idec Ma Inc. |
Neonatal fc receptor (fcrn)-binding polypeptide variants, dimeric fc binding proteins and methods related thereto
|
|
EP1701979A2
(en)
|
2003-12-03 |
2006-09-20 |
Xencor, Inc. |
Optimized antibodies that target the epidermal growth factor receptor
|
|
WO2005053742A1
(en)
|
2003-12-04 |
2005-06-16 |
Kyowa Hakko Kogyo Co., Ltd. |
Medicine containing antibody composition
|
|
AU2004297616B2
(en)
|
2003-12-04 |
2008-12-18 |
Xencor, Inc. |
Methods of generating variant proteins with increased host string content and compositions thereof
|
|
AR048210A1
(en)
|
2003-12-19 |
2006-04-12 |
Chugai Pharmaceutical Co Ltd |
A PREVENTIVE AGENT FOR VASCULITIS.
|
|
WO2005077981A2
(en)
|
2003-12-22 |
2005-08-25 |
Xencor, Inc. |
Fc POLYPEPTIDES WITH NOVEL Fc LIGAND BINDING SITES
|
|
AR048335A1
(en)
|
2004-03-24 |
2006-04-19 |
Chugai Pharmaceutical Co Ltd |
THERAPEUTIC AGENTS FOR INTERNAL EAR DISORDERS CONTAINING AN IL-6 ANTAGONIST AS AN ACTIVE INGREDIENT
|
|
EP1737890A2
(en)
|
2004-03-24 |
2007-01-03 |
Xencor, Inc. |
Immunoglobulin variants outside the fc region
|
|
MXPA06011199A
(en)
|
2004-03-31 |
2007-04-16 |
Genentech Inc |
Humanized anti-tgf-beta antibodies.
|
|
WO2005123780A2
(en)
|
2004-04-09 |
2005-12-29 |
Protein Design Labs, Inc. |
Alteration of fcrn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
US7785903B2
(en)
|
2004-04-09 |
2010-08-31 |
Genentech, Inc. |
Variable domain library and uses
|
|
PL1737891T3
(en)
|
2004-04-13 |
2013-08-30 |
Hoffmann La Roche |
Anti-p-selectin antibodies
|
|
EP1773391A4
(en)
|
2004-06-25 |
2009-01-21 |
Medimmune Inc |
Increasing the production of recombinant antibodies in mammalian cells by site-directed mutagenesis
|
|
WO2006085967A2
(en)
|
2004-07-09 |
2006-08-17 |
Xencor, Inc. |
OPTIMIZED ANTI-CD20 MONOCONAL ANTIBODIES HAVING Fc VARIANTS
|
|
CN103172731A
(en)
|
2004-07-15 |
2013-06-26 |
赞科股份有限公司 |
Optimized Fc variants
|
|
JP5055603B2
(en)
|
2004-08-04 |
2012-10-24 |
メントリック・バイオテック・リミテッド・ライアビリティ・カンパニー |
Mutated Fc region
|
|
JP2008510466A
(en)
|
2004-08-19 |
2008-04-10 |
ジェネンテック・インコーポレーテッド |
Polypeptide variants with altered effector function
|
|
TWI380996B
(en)
|
2004-09-17 |
2013-01-01 |
Hoffmann La Roche |
Anti-ox40l antibodies
|
|
NZ553500A
(en)
|
2004-09-23 |
2009-11-27 |
Genentech Inc Genentech Inc |
Cysteine engineered antibodies and conjugates withCysteine engineered antibodies and conjugates with a free cysteine amino acid in the heavy chain a free cysteine amino acid in the heavy chain
|
|
JO3000B1
(en)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
Antibody Formulations.
|
|
WO2006047350A2
(en)
|
2004-10-21 |
2006-05-04 |
Xencor, Inc. |
IgG IMMUNOGLOBULIN VARIANTS WITH OPTIMIZED EFFECTOR FUNCTION
|
|
AU2005299716B2
(en)
|
2004-10-22 |
2012-09-06 |
Amgen Inc. |
Methods for refolding of recombinant antibodies
|
|
AU2005302453A1
(en)
|
2004-10-29 |
2006-05-11 |
Medimmune, Llc |
Methods of preventing and treating RSV infections and related conditions
|
|
CA2587766A1
(en)
|
2004-11-10 |
2007-03-01 |
Macrogenics, Inc. |
Engineering fc antibody regions to confer effector function
|
|
AU2005304624B2
(en)
|
2004-11-12 |
2010-10-07 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
US8802820B2
(en)
|
2004-11-12 |
2014-08-12 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
WO2006071877A2
(en)
|
2004-12-27 |
2006-07-06 |
Progenics Pharmaceuticals (Nevada), Inc. |
Orally deliverable and anti-toxin antibodies and methods for making and using them
|
|
AU2006204459B2
(en)
|
2005-01-05 |
2012-11-01 |
F-Star Therapeutics Limited |
Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions
|
|
JP4986633B2
(en)
|
2005-01-12 |
2012-07-25 |
協和発酵キリン株式会社 |
Stabilized human IgG2 and IgG3 antibodies
|
|
AU2006204791A1
(en)
|
2005-01-12 |
2006-07-20 |
Xencor, Inc |
Antibodies and Fc fusion proteins with altered immunogenicity
|
|
US7700099B2
(en)
|
2005-02-14 |
2010-04-20 |
Merck & Co., Inc. |
Non-immunostimulatory antibody and compositions containing the same
|
|
CA2602663A1
(en)
|
2005-03-31 |
2006-10-05 |
Xencor, Inc. |
Fc variants with optimized properties
|
|
MX2007013058A
(en)
|
2005-04-20 |
2008-02-22 |
Amgen Fremont Inc |
High affinity fully human monoclonal antibodies to interleukin-8 and epitopes for such antibodies.
|
|
US8163881B2
(en)
|
2005-05-31 |
2012-04-24 |
The Board Of Regents Of The University Of Texas System |
Immunoglobulin molecules with improved characteristics
|
|
DK2573114T3
(en)
|
2005-08-10 |
2016-07-04 |
Macrogenics Inc |
The identification and production of antibodies with variant Fc regions, and methods of using same
|
|
CU23578A1
(en)
*
|
2005-09-16 |
2010-09-30 |
Ct Ingenieria Genetica Biotech |
VIRUS CAPSID PROTEIN DENGES INDUCTIVE PROTECTION RESPONSE AND VACCINE COMPOSITION
|
|
AU2006297173A1
(en)
|
2005-09-29 |
2007-04-12 |
Viral Logic Systems Technology Corp. |
Immunomodulatory compositions and uses therefor
|
|
WO2007041635A2
(en)
|
2005-10-03 |
2007-04-12 |
Xencor, Inc. |
Fc variants with optimized fc receptor binding properties
|
|
CA2625998C
(en)
|
2005-10-06 |
2015-12-01 |
Xencor, Inc. |
Optimized anti-cd30 antibodies
|
|
US8470316B2
(en)
|
2005-10-14 |
2013-06-25 |
Chugai Seiyaku Kabushiki Kaisha |
Agents for suppressing damage to transplanted islets after islet transplantation
|
|
CA2626688C
(en)
|
2005-10-21 |
2017-10-03 |
Chugai Seiyaku Kabushiki Kaisha |
Agents for treating cardiopathy
|
|
EP1957531B1
(en)
|
2005-11-07 |
2016-04-13 |
Genentech, Inc. |
Binding polypeptides with diversified and consensus vh/vl hypervariable sequences
|
|
CU23586A1
(en)
*
|
2005-11-22 |
2010-10-30 |
Ct Ingenieria Genetica Biotech |
METHODS AND PROTEINS FOR THE PROPHLACTIC AND / OR THERAPEUTIC TREATMENT OF THE FOUR SEROTYPES OF THE DENGUE VIRUS AND OTHER FLAVIVIRUS
|
|
US20070237764A1
(en)
|
2005-12-02 |
2007-10-11 |
Genentech, Inc. |
Binding polypeptides with restricted diversity sequences
|
|
AU2007212147A1
(en)
|
2006-02-03 |
2007-08-16 |
Medimmune, Llc |
Protein formulations
|
|
NZ591252A
(en)
|
2006-03-17 |
2012-06-29 |
Biogen Idec Inc |
Methods of designing antibody or antigen binding fragments thereof with substituted non-covarying amino acids
|
|
CA2644663A1
(en)
|
2006-03-23 |
2007-09-27 |
Kirin Pharma Kabushiki Kaisha |
Agonist antibody to human thrombopoietin receptor
|
|
EP1999149A4
(en)
|
2006-03-28 |
2010-01-20 |
Biogen Idec Inc |
Anti-igf-ir antibodies and uses thereof
|
|
DK2006381T3
(en)
|
2006-03-31 |
2016-02-22 |
Chugai Pharmaceutical Co Ltd |
PROCEDURE FOR REGULATING ANTIBODIES BLOOD PHARMACOKINETICS
|
|
JP5144499B2
(en)
|
2006-03-31 |
2013-02-13 |
中外製薬株式会社 |
Antibody modification method for purifying bispecific antibodies
|
|
US9260516B2
(en)
|
2006-04-07 |
2016-02-16 |
Osaka University |
Method for promoting muscle regeneration by administering an antibody to the IL-6 receptor
|
|
AR060871A1
(en)
|
2006-05-09 |
2008-07-16 |
Genentech Inc |
UNION OF POLYPEPTIDES WITH OPTIMIZED SUPERCONTIGES
|
|
PE20080943A1
(en)
|
2006-06-23 |
2008-09-27 |
Smithkline Beecham Corp |
SALT TOLUENOSULPHONATE OF 4 - {[6-CHLORO-3 - ({[(2-CHLORO-3-FLUOROPHENYL) AMINO] CARBONYL} AMINO) -2-HYDROXYPHENYL] SULFONYL} -1-PIPERAZINACARBOXYLATE 1,1-DIMETHYLETHYL ANTAGON IL-8 RECEIVER
|
|
AR062223A1
(en)
|
2006-08-09 |
2008-10-22 |
Glycart Biotechnology Ag |
MOLECULES OF ADHESION TO THE ANTIGEN THAT ADHER TO EGFR, VECTORS THAT CODE THEM, AND THEIR USES OF THESE
|
|
HRP20140331T1
(en)
|
2006-08-14 |
2014-05-09 |
Xencor, Inc. |
OPTIMIZED CD19 DIRECTED ANTIBODIES
|
|
WO2008027236A2
(en)
|
2006-08-30 |
2008-03-06 |
Genentech, Inc. |
Multispecific antibodies
|
|
EP2066349B1
(en)
|
2006-09-08 |
2012-03-28 |
MedImmune, LLC |
Humanized anti-cd19 antibodies and their use in treatment of tumors, transplantation and autoimmune diseases
|
|
WO2008036688A2
(en)
|
2006-09-18 |
2008-03-27 |
Xencor, Inc. |
Optimized antibodies that target hm1.24
|
|
WO2008121160A2
(en)
|
2006-11-21 |
2008-10-09 |
Xencor, Inc. |
Optimized antibodies that target cd5
|
|
CN100455598C
(en)
|
2006-11-29 |
2009-01-28 |
中国抗体制药有限公司 |
Functional humanized anti-human CD20 antibody and application thereof
|
|
US20080226635A1
(en)
|
2006-12-22 |
2008-09-18 |
Hans Koll |
Antibodies against insulin-like growth factor I receptor and uses thereof
|
|
WO2008091798A2
(en)
|
2007-01-22 |
2008-07-31 |
Xencor, Inc. |
Optimized ca9 antibodies and methods of using the same
|
|
EP2125893A2
(en)
|
2007-01-23 |
2009-12-02 |
Xencor, Inc. |
Optimized cd40 antibodies and methods of using the same
|
|
WO2008092117A2
(en)
|
2007-01-25 |
2008-07-31 |
Xencor, Inc. |
Immunoglobulins with modifications in the fcr binding region
|
|
WO2008098115A2
(en)
|
2007-02-07 |
2008-08-14 |
Xencor, Inc. |
Optimized igf-1r antibodies and methods of using the same
|
|
EP2144931A2
(en)
|
2007-04-04 |
2010-01-20 |
The Government Of The U.S.A, As Represented By The Secretary, Dept. Of Health And Human Services |
Monoclonal antibodies against dengue and other viruses with deletion in fc region
|
|
CL2008001071A1
(en)
|
2007-04-17 |
2009-05-22 |
Smithkline Beecham Corp |
Method to obtain penta-specific antibody against human il-8 / cxcl8, gro-alpha / cxcl1, gro-beta / cxcl2), gro-gamma / cxcl3 and ena-78 / cxcl5; penta-specific antibody; production process of the same; vector, hybridoma or cella that comprises it; pharmaceutical composition; use to treat copd, other diseases.
|
|
CN100592373C
(en)
|
2007-05-25 |
2010-02-24 |
群康科技(深圳)有限公司 |
Liquid crystal display panel driving device and driving method thereof
|
|
EP2708557A1
(en)
|
2007-05-30 |
2014-03-19 |
Xencor, Inc. |
Method and compositions for inhibiting CD32B expressing cells
|
|
US20100291023A1
(en)
|
2007-05-31 |
2010-11-18 |
Genmab A/S |
Method for extending the half-life of exogenous or endogenous soluble molecules
|
|
RU2010102064A
(en)
|
2007-06-25 |
2011-07-27 |
Эсбатек, Эн Элкон Биомедикал Рисёрч Юнит Ллк (Ch) |
METHOD OF DESIGNING BASED ON DETERMINATION OF SEQUENCES, METHOD OF OPTIMIZATION OF SINGLE-CHAIN ANTIBODIES
|
|
NZ581468A
(en)
|
2007-06-25 |
2012-09-28 |
Esbatech Alcon Biomed Res Unit |
Methods of modifying antibodies, and modified antibodies with improved functional properties
|
|
WO2009026117A2
(en)
|
2007-08-16 |
2009-02-26 |
Glaxo Group Limited |
Novel compounds
|
|
JP2010537985A
(en)
|
2007-08-28 |
2010-12-09 |
バイオジェン アイデック マサチューセッツ インコーポレイテッド |
Anti-IGF-1R antibodies and uses thereof
|
|
WO2009032782A2
(en)
|
2007-08-28 |
2009-03-12 |
Biogen Idec Ma Inc. |
Compositions that bind multiple epitopes of igf-1r
|
|
EP2031064A1
(en)
|
2007-08-29 |
2009-03-04 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Method for increasing protein titres
|
|
EP2197911A2
(en)
|
2007-09-14 |
2010-06-23 |
Amgen Inc. |
Homogeneous antibody populations
|
|
ES2566957T3
(en)
|
2007-09-26 |
2016-04-18 |
Chugai Seiyaku Kabushiki Kaisha |
Constant region of modified antibody
|
|
DK2202245T3
(en)
|
2007-09-26 |
2016-11-21 |
Chugai Pharmaceutical Co Ltd |
A method of modifying an antibody isoelectric point VIA amino acid substitution in CDR
|
|
PE20140132A1
(en)
|
2007-09-26 |
2014-02-14 |
Chugai Pharmaceutical Co Ltd |
IL-6 ANTI-RECEPTOR ANTIBODY
|
|
JO3076B1
(en)
|
2007-10-17 |
2017-03-15 |
Janssen Alzheimer Immunotherap |
Immunotherapy regimes dependent on apoe status
|
|
KR20160074019A
(en)
|
2007-12-05 |
2016-06-27 |
추가이 세이야쿠 가부시키가이샤 |
Anti-NR10 antibody and use thereof
|
|
PL2235059T3
(en)
|
2007-12-26 |
2015-08-31 |
Xencor Inc |
Fc variants with altered binding to fcrn
|
|
SI2235064T1
(en)
|
2008-01-07 |
2016-04-29 |
Amgen Inc. |
Method for making antibody fc-heterodimeric molecules using electrostatic steering effects
|
|
WO2009100309A2
(en)
|
2008-02-08 |
2009-08-13 |
Medimmune, Llc |
Anti-ifnar1 antibodies with reduced fc ligand affinity
|
|
CN101343319B
(en)
*
|
2008-04-10 |
2012-05-09 |
中国人民解放军第三军医大学 |
Monoclonal antibody of anti-dengue virus E protein, preparation method and application thereof
|
|
UA121453C2
(en)
|
2008-04-11 |
2020-06-10 |
Чугей Сейяку Кабусікі Кайся |
METHOD OF PREPARATION OF PHARMACEUTICAL COMPOSITION CONTAINING ANTIBODY
|
|
PT2853545T
(en)
|
2008-09-17 |
2016-08-26 |
Xencor Inc |
Antibody specific for ige
|
|
WO2010043977A2
(en)
*
|
2008-10-13 |
2010-04-22 |
Institute For Research In Biomedicine |
Dengue virus neutralizing antibodies and uses thereof
|
|
CN110317272A
(en)
|
2008-10-14 |
2019-10-11 |
霍夫曼-拉罗奇有限公司 |
Immunoglobulin variants and application thereof
|
|
EP2409991B1
(en)
|
2009-03-19 |
2017-05-03 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody constant region variant
|
|
TWI682995B
(en)
|
2009-03-19 |
2020-01-21 |
日商中外製藥股份有限公司 |
Antibody constant region alteration
|
|
EP2233500A1
(en)
|
2009-03-20 |
2010-09-29 |
LFB Biotechnologies |
Optimized Fc variants
|
|
GB0914691D0
(en)
|
2009-08-21 |
2009-09-30 |
Lonza Biologics Plc |
Immunoglobulin variants
|
|
JP5837821B2
(en)
|
2009-09-24 |
2015-12-24 |
中外製薬株式会社 |
Antibody constant region variants
|
|
WO2011091078A2
(en)
|
2010-01-19 |
2011-07-28 |
Xencor, Inc. |
Antibody fc variants with enhanced complement activity
|
|
US20120315267A1
(en)
|
2010-02-09 |
2012-12-13 |
Glaxosmithkline Llc |
Novel uses
|
|
WO2011108714A1
(en)
|
2010-03-04 |
2011-09-09 |
中外製薬株式会社 |
Antibody constant region variant
|
|
TWI667257B
(en)
|
2010-03-30 |
2019-08-01 |
中外製藥股份有限公司 |
Antibodies with modified affinity to fcrn that promote antigen clearance
|
|
AU2011283694B2
(en)
|
2010-07-29 |
2017-04-13 |
Xencor, Inc. |
Antibodies with modified isoelectric points
|
|
KR102385507B1
(en)
|
2010-11-30 |
2022-04-12 |
추가이 세이야쿠 가부시키가이샤 |
Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly
|
|
KR101904232B1
(en)
|
2010-12-14 |
2018-10-05 |
내셔널 유니버시티 오브 싱가포르 |
Human monoclonal antibody with specificity for dengue virus serotype 1 e protein and uses thereof
|
|
EP2662385A4
(en)
|
2011-01-07 |
2015-11-11 |
Chugai Pharmaceutical Co Ltd |
METHOD FOR IMPROVING PHYSICAL PROPERTIES OF ANTIBODIES
|
|
CA2827923C
(en)
|
2011-02-25 |
2021-11-23 |
Chugai Seiyaku Kabushiki Kaisha |
Fc.gamma.riib-specific fc antibody
|
|
WO2012132067A1
(en)
|
2011-03-30 |
2012-10-04 |
中外製薬株式会社 |
Retention of antigen-binding molecules in blood plasma and method for modifying immunogenicity
|
|
CA3025762C
(en)
|
2011-05-04 |
2021-11-09 |
Omeros Corporation |
Compositions for inhibiting masp-2 dependent complement activation
|
|
WO2013012733A1
(en)
|
2011-07-15 |
2013-01-24 |
Biogen Idec Ma Inc. |
Heterodimeric fc regions, binding molecules comprising same, and methods relating thereto
|
|
TW201817745A
(en)
|
2011-09-30 |
2018-05-16 |
日商中外製藥股份有限公司 |
Therapeutic antigen-binding molecule having an FcRn binding domain that promotes antigen clearance
|
|
CN107287660A
(en)
|
2011-09-30 |
2017-10-24 |
中外制药株式会社 |
Ion concentration dependence binding molecule library
|
|
EP2762166B1
(en)
|
2011-09-30 |
2019-09-18 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecules for promoting elimination of antigens
|
|
SG10201609301QA
(en)
|
2011-11-30 |
2016-12-29 |
Chugai Pharmaceutical Co Ltd |
Drug containing carrier into cell for forming immune complex
|
|
WO2013089647A1
(en)
*
|
2011-12-16 |
2013-06-20 |
Agency For Science, Technology And Research |
Binding molecules against dengue virus and uses thereof
|
|
TWI593705B
(en)
*
|
2011-12-28 |
2017-08-01 |
Chugai Pharmaceutical Co Ltd |
Humanized anti-epiregulin antibody and cancer therapeutic agent containing the antibody as an active ingredient
|
|
CA2865158C
(en)
|
2012-02-24 |
2022-11-01 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule for promoting disappearance of antigen via fc.gamma.riib
|
|
CN104428312A
(en)
|
2012-04-02 |
2015-03-18 |
北卡罗来纳-查佩尔山大学 |
Methods and compositions for dengue virus epitopes
|
|
EP2844290A4
(en)
|
2012-05-01 |
2015-12-16 |
Glaxosmithkline Llc |
NEW ANTIBODIES
|
|
US9556254B2
(en)
*
|
2012-05-14 |
2017-01-31 |
The Usa, As Represented By The Secretary, Dept. Of Health And Human Services |
Cross-reactive antibodies against dengue virus and uses thereof
|
|
CN107964042B
(en)
|
2012-05-30 |
2022-04-19 |
中外制药株式会社 |
Target tissue specific antigen binding molecules
|
|
DK2857419T3
(en)
|
2012-05-30 |
2021-03-29 |
Chugai Pharmaceutical Co Ltd |
Antigen-binding molecule for the elimination of aggregated antigens
|
|
BR112015000167B1
(en)
|
2012-07-06 |
2021-11-23 |
Genmab B.V. |
DIMERIC PROTEIN, PROTEIN, COMPOSITION, KIT OF PARTS AND THEIR USES, AS WELL AS A METHOD TO INCREASE THE OLIGOMERIZATION IN SOLUTION OF A DIMERIC PROTEIN COMPRISING A FIRST AND SECOND POLYPEPTIDE, EACH COMPRISING AT LEAST ONE CH2 AND CH3 REGIONS HUMAN AND VARIANT DIMER PROTEIN
|
|
KR20200102524A
(en)
*
|
2012-08-07 |
2020-08-31 |
메사추세츠 인스티튜트 오브 테크놀로지 |
Anti-dengue virus antibodies and uses thereof
|
|
AU2013306700B2
(en)
|
2012-08-24 |
2019-05-02 |
Chugai Seiyaku Kabushiki Kaisha |
FcgammaRIIb-specific Fc region variant
|
|
US9701759B2
(en)
|
2013-01-14 |
2017-07-11 |
Xencor, Inc. |
Heterodimeric proteins
|
|
JP2016505633A
(en)
|
2013-01-24 |
2016-02-25 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited |
TNFα antigen binding protein
|
|
WO2014145159A2
(en)
|
2013-03-15 |
2014-09-18 |
Permeon Biologics, Inc. |
Charge-engineered antibodies or compositions of penetration-enhanced targeting proteins and methods of use
|
|
CN111138543B
(en)
|
2013-03-15 |
2024-06-11 |
Xencor股份有限公司 |
Heterodimer protein
|
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
|
WO2014163101A1
(en)
*
|
2013-04-02 |
2014-10-09 |
中外製薬株式会社 |
Fc region variant
|
|
KR20160021125A
(en)
|
2013-05-17 |
2016-02-24 |
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|
|
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(en)
|
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|
|
EP3080159A4
(en)
*
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
*
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|