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BR112017009728A2 - anticorpos isolados, ácido nucleico isolado, vetor, célula hospedeira, método para produzir o anticorpo, composição, usos de um anticorpo e métodos de tratamento de um distúrbio - Google Patents

anticorpos isolados, ácido nucleico isolado, vetor, célula hospedeira, método para produzir o anticorpo, composição, usos de um anticorpo e métodos de tratamento de um distúrbio

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Publication number
BR112017009728A2
BR112017009728A2 BR112017009728-1A BR112017009728A BR112017009728A2 BR 112017009728 A2 BR112017009728 A2 BR 112017009728A2 BR 112017009728 A BR112017009728 A BR 112017009728A BR 112017009728 A2 BR112017009728 A2 BR 112017009728A2
Authority
BR
Brazil
Prior art keywords
antibody
methods
disorder
vector
treating
Prior art date
Application number
BR112017009728-1A
Other languages
English (en)
Inventor
E. Hass Philip
Hazen Meredith
Hsiao Yi-Chun
Khosla Rajita
R. Nakamura Gerald
Seshasayee Dhaya
Van Lookeren Campagne Menno
Xi Hongkang
Zhai Wenwu
Bevers Jack Iii
Chiang Nancy
Original Assignee
Genentech, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech, Inc. filed Critical Genentech, Inc.
Publication of BR112017009728A2 publication Critical patent/BR112017009728A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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Abstract

a invenção fornece anticorpos de interleucina-33 (il-33) e métodos de uso dos mesmos.
BR112017009728-1A 2014-11-10 2015-11-10 anticorpos isolados, ácido nucleico isolado, vetor, célula hospedeira, método para produzir o anticorpo, composição, usos de um anticorpo e métodos de tratamento de um distúrbio BR112017009728A2 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462077876P 2014-11-10 2014-11-10
US62/077,876 2014-11-10
US201562165732P 2015-05-22 2015-05-22
US62/165,732 2015-05-22
PCT/US2015/060008 WO2016077381A1 (en) 2014-11-10 2015-11-10 Anti-interleukin-33 antibodies and uses thereof

Publications (1)

Publication Number Publication Date
BR112017009728A2 true BR112017009728A2 (pt) 2018-02-06

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Application Number Title Priority Date Filing Date
BR112017009728-1A BR112017009728A2 (pt) 2014-11-10 2015-11-10 anticorpos isolados, ácido nucleico isolado, vetor, célula hospedeira, método para produzir o anticorpo, composição, usos de um anticorpo e métodos de tratamento de um distúrbio

Country Status (18)

Country Link
US (3) US10093730B2 (pt)
EP (2) EP3218403B1 (pt)
JP (1) JP6929771B2 (pt)
KR (1) KR20170080604A (pt)
CN (1) CN107172879B (pt)
AU (1) AU2015346460A1 (pt)
BR (1) BR112017009728A2 (pt)
CA (1) CA2960297A1 (pt)
CO (1) CO2017005650A2 (pt)
CR (1) CR20170240A (pt)
EA (1) EA201791029A1 (pt)
IL (1) IL251248A0 (pt)
MX (1) MX2017006094A (pt)
PE (1) PE20170910A1 (pt)
PH (1) PH12017500861A1 (pt)
SG (1) SG11201703767XA (pt)
TW (1) TWI705976B (pt)
WO (1) WO2016077381A1 (pt)

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US20150111275A1 (en) * 2012-06-11 2015-04-23 Daniel V. Palanker Optical regulation of gene expression in the retina
EP3092253B1 (en) 2014-01-10 2021-03-17 AnaptysBio, Inc. Antibodies directed against interleukin-33 (il-33)
WO2016077366A1 (en) 2014-11-10 2016-05-19 Genentec, Inc. Therapeutic and diagnostic methods for il-33-mediated disorders
BR112017009728A2 (pt) 2014-11-10 2018-02-06 Genentech, Inc. anticorpos isolados, ácido nucleico isolado, vetor, célula hospedeira, método para produzir o anticorpo, composição, usos de um anticorpo e métodos de tratamento de um distúrbio
CA2992602A1 (en) 2015-09-23 2017-03-30 Genentech, Inc. Optimized variants of anti-vegf antibodies
JP2019516362A (ja) 2016-04-27 2019-06-20 ファイザー・インク 抗ｉｌ−３３抗体、その組成物、方法および使用
CN114617962A (zh) 2016-04-27 2022-06-14 艾伯维公司 使用抗-il-13抗体治疗il-13活性在其中有害的疾病的方法
US20190225682A1 (en) * 2016-09-02 2019-07-25 180 Therapeutics Lp Method of treating localized fibrotic disorders using an il-33/tnf bispecific antibody
US20190202907A1 (en) * 2016-09-02 2019-07-04 180 Therapeutics Lp Method of treating systemic fibrotic disorders using an il-33/tnf bispecific antibody
JOP20190093A1 (ar) 2016-10-28 2019-04-25 Lilly Co Eli أجسام مضادة لـ il-33 واستخداماتها
TWI857389B (zh) 2016-12-01 2024-10-01 美商再生元醫藥公司 治療發炎症狀的方法
US10738131B2 (en) 2017-02-10 2020-08-11 Genentech, Inc. Anti-tryptase antibodies, compositions thereof, and uses thereof
KR102605045B1 (ko) 2017-04-13 2023-11-27 리제너론 파마슈티칼스 인코포레이티드 Il33 및 il1rl1을 코딩하는 유전자에서의 위험 대립유전자를 갖는 환자에서의 폐 질환의 치료 및 저해
CN110997725B (zh) 2017-06-12 2024-08-09 蓝鳍生物医药公司 抗-il1rap抗体和抗体药物缀合物
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