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ECSP21023271A - Anticuerpos cd20 con función del efector y afinidad de enlace al receptor fc mejoradas - Google Patents

Anticuerpos cd20 con función del efector y afinidad de enlace al receptor fc mejoradas

Info

Publication number
ECSP21023271A
ECSP21023271A ECSENADI202123271A ECDI202123271A ECSP21023271A EC SP21023271 A ECSP21023271 A EC SP21023271A EC SENADI202123271 A ECSENADI202123271 A EC SENADI202123271A EC DI202123271 A ECDI202123271 A EC DI202123271A EC SP21023271 A ECSP21023271 A EC SP21023271A
Authority
EC
Ecuador
Prior art keywords
relates
present
antibodies
effector function
abms
Prior art date
Application number
ECSENADI202123271A
Other languages
English (en)
Inventor
Peter Brünker
Tobias Suter
Ursula Püntener
Ekkehard Mössner
Pablo Umana
Claudia Ferrara
Original Assignee
Roche Glycart Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34572912&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP21023271(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Roche Glycart Ag filed Critical Roche Glycart Ag
Publication of ECSP21023271A publication Critical patent/ECSP21023271A/es

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Abstract

La presente invención se refiere a moléculas de enlace a antígenos (ABM). En modalidades particulares, la presente invención se refiere a anticuerpos monoclonales recombinantes, incluyendo anticuerpos quiméricos, primatizados o humanizados específicos para el CD20 humano. Además, la presente invención se refiere a moléculas de ácidos nucleicos que codifican tales ABM, y vectores y células hospederas que comprenden tales moléculas de ácidos nucleicos. La invención se refiere además a métodos para la producción de las ABM de la invención, y a métodos de uso de estas ABM en el tratamiento de la enfermedad. Además, la presente invención se refiere a ABM con glicosilación modificada que tiene propiedades terapéuticas modificadas, incluyendo anticuerpos con función del efector incrementada y enlace al receptor Fc incrementado.
ECSENADI202123271A 2003-11-05 2021-04-14 Anticuerpos cd20 con función del efector y afinidad de enlace al receptor fc mejoradas ECSP21023271A (es)

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