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DE3788524D1 - Verfahren zur Herstellung von Proteinprodukten in Aspergillus Oryzae und in Aspergillus zu verwendender Promotor. - Google Patents

Verfahren zur Herstellung von Proteinprodukten in Aspergillus Oryzae und in Aspergillus zu verwendender Promotor.

Info

Publication number
DE3788524D1
DE3788524D1 DE87103806T DE3788524T DE3788524D1 DE 3788524 D1 DE3788524 D1 DE 3788524D1 DE 87103806 T DE87103806 T DE 87103806T DE 3788524 T DE3788524 T DE 3788524T DE 3788524 D1 DE3788524 D1 DE 3788524D1
Authority
DE
Germany
Prior art keywords
promoter
aspergillus
production
sequences
host
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE87103806T
Other languages
English (en)
Other versions
DE3788524T2 (de
DE3788524T3 (de
Inventor
Esper Boel
Tove Christensen
Helle Fabricius Woeldike
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novozymes AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8102403&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3788524(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of DE3788524D1 publication Critical patent/DE3788524D1/de
Publication of DE3788524T2 publication Critical patent/DE3788524T2/de
Application granted granted Critical
Publication of DE3788524T3 publication Critical patent/DE3788524T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67General methods for enhancing the expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18Carboxylic ester hydrolases (3.1.1)
    • C12N9/20Triglyceride splitting, e.g. by means of lipase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2408Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411Amylases
    • C12N9/2414Alpha-amylase (3.2.1.1.)
    • C12N9/2417Alpha-amylase (3.2.1.1.) from microbiological source
    • C12N9/242Fungal source
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6478Aspartic endopeptidases (3.4.23)
    • C12N9/6481Pepsins (3.4.23.1; 3.4.23.2; 3.4.23.3)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE3788524T 1986-03-17 1987-03-16 Verfahren zur Herstellung von Proteinprodukten in Aspergillus Oryzae und in Aspergillus zu verwendender Promotor. Expired - Lifetime DE3788524T3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK122686A DK122686D0 (da) 1986-03-17 1986-03-17 Fremstilling af proteiner

Publications (3)

Publication Number Publication Date
DE3788524D1 true DE3788524D1 (de) 1994-02-03
DE3788524T2 DE3788524T2 (de) 1994-05-11
DE3788524T3 DE3788524T3 (de) 2003-04-24

Family

ID=8102403

Family Applications (2)

Application Number Title Priority Date Filing Date
DE3752379T Expired - Lifetime DE3752379T2 (de) 1986-03-17 1987-03-16 Verfahren zur Herstellung von Proteinprodukten in Aspergillus-Oryzae und in Aspergillus zu verwendender Promotor
DE3788524T Expired - Lifetime DE3788524T3 (de) 1986-03-17 1987-03-16 Verfahren zur Herstellung von Proteinprodukten in Aspergillus Oryzae und in Aspergillus zu verwendender Promotor.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE3752379T Expired - Lifetime DE3752379T2 (de) 1986-03-17 1987-03-16 Verfahren zur Herstellung von Proteinprodukten in Aspergillus-Oryzae und in Aspergillus zu verwendender Promotor

Country Status (9)

Country Link
EP (3) EP0489718B1 (de)
JP (4) JPH0665316B2 (de)
AT (2) ATE282093T1 (de)
CA (1) CA1341593C (de)
DE (2) DE3752379T2 (de)
DK (1) DK122686D0 (de)
ES (1) ES2061446T5 (de)
FI (2) FI108147B (de)
IE (2) IE63169B1 (de)

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* Cited by examiner, † Cited by third party
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US6004785A (en) 1985-08-29 1999-12-21 Genencor International Inc. Heterologous polypeptides expressed in filamentous fungi, processes for making same, and vectors for making same
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US5766912A (en) 1986-03-17 1998-06-16 Novo Nordisk A/S Humicola lipase produced in aspergillus
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DE3752379D1 (de) 2004-12-16
JPH0751067A (ja) 1995-02-28
FI108147B (fi) 2001-11-30
FI20011797L (fi) 2001-09-12
EP0238023A3 (en) 1989-02-22
JP3005618B2 (ja) 2000-01-31
JP3903165B2 (ja) 2007-04-11
ES2061446T3 (es) 1994-12-16
DE3788524T2 (de) 1994-05-11
EP1502952A3 (de) 2005-05-11
EP0238023B1 (de) 1993-12-22
DK122686D0 (da) 1986-03-17
JP2003153696A (ja) 2003-05-27
FI871144A0 (fi) 1987-03-16
EP0238023A2 (de) 1987-09-23
CA1341593C (en) 2009-04-21
FI112376B (fi) 2003-11-28
EP0238023B2 (de) 2002-10-02
JPS62272988A (ja) 1987-11-27
EP0489718A1 (de) 1992-06-10
ATE98993T1 (de) 1994-01-15
IE870682L (en) 1987-09-17
EP1502952A2 (de) 2005-02-02
DE3752379T2 (de) 2005-10-20
IE63169B1 (en) 1995-03-22
FI871144L (fi) 1987-09-18
IE940343L (en) 1987-09-17
EP0489718B1 (de) 2004-11-10
ES2061446T5 (es) 2003-04-01
JPH0665316B2 (ja) 1994-08-24
JPH10276787A (ja) 1998-10-20
ATE282093T1 (de) 2004-11-15
DE3788524T3 (de) 2003-04-24

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