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EP2345727A3 - Promotoren aus Fungi für die Expression eines Gens in einer Zelle aus Fungus - Google Patents

Promotoren aus Fungi für die Expression eines Gens in einer Zelle aus Fungus Download PDF

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Publication number
EP2345727A3
EP2345727A3 EP11155313A EP11155313A EP2345727A3 EP 2345727 A3 EP2345727 A3 EP 2345727A3 EP 11155313 A EP11155313 A EP 11155313A EP 11155313 A EP11155313 A EP 11155313A EP 2345727 A3 EP2345727 A3 EP 2345727A3
Authority
EP
European Patent Office
Prior art keywords
fungal
gene
promoter
expressing
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP11155313A
Other languages
English (en)
French (fr)
Other versions
EP2345727A2 (de
Inventor
Thibaut José Wenzel
Noël Nicolaas Maria Elisabeth van Peij
Hein Stam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Priority to EP11155313A priority Critical patent/EP2345727A3/de
Publication of EP2345727A2 publication Critical patent/EP2345727A2/de
Publication of EP2345727A3 publication Critical patent/EP2345727A3/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/38—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Aspergillus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
EP11155313A 2004-04-16 2005-04-18 Promotoren aus Fungi für die Expression eines Gens in einer Zelle aus Fungus Withdrawn EP2345727A3 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP11155313A EP2345727A3 (de) 2004-04-16 2005-04-18 Promotoren aus Fungi für die Expression eines Gens in einer Zelle aus Fungus

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP04076179 2004-04-16
EP04076180 2004-04-16
EP04076176 2004-04-16
EP04076182 2004-04-16
EP04076175 2004-04-16
EP11155313A EP2345727A3 (de) 2004-04-16 2005-04-18 Promotoren aus Fungi für die Expression eines Gens in einer Zelle aus Fungus
EP05735830A EP1776461A2 (de) 2004-04-16 2005-04-18 Pilzpromotoren zur expression eines gens in einer pilzzelle

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
WOPCT/EP2005/051696 Previously-Filed-Application 2005-04-18
EP05735830.1 Division 2005-04-18

Publications (2)

Publication Number Publication Date
EP2345727A2 EP2345727A2 (de) 2011-07-20
EP2345727A3 true EP2345727A3 (de) 2011-11-23

Family

ID=35150555

Family Applications (3)

Application Number Title Priority Date Filing Date
EP11155313A Withdrawn EP2345727A3 (de) 2004-04-16 2005-04-18 Promotoren aus Fungi für die Expression eines Gens in einer Zelle aus Fungus
EP05735830A Withdrawn EP1776461A2 (de) 2004-04-16 2005-04-18 Pilzpromotoren zur expression eines gens in einer pilzzelle
EP11155312A Withdrawn EP2345726A3 (de) 2004-04-16 2005-04-18 Promotoren aus Fungi für die Expression eines Gens in einer Zelle aus Fungus

Family Applications After (2)

Application Number Title Priority Date Filing Date
EP05735830A Withdrawn EP1776461A2 (de) 2004-04-16 2005-04-18 Pilzpromotoren zur expression eines gens in einer pilzzelle
EP11155312A Withdrawn EP2345726A3 (de) 2004-04-16 2005-04-18 Promotoren aus Fungi für die Expression eines Gens in einer Zelle aus Fungus

Country Status (7)

Country Link
US (2) US8211667B2 (de)
EP (3) EP2345727A3 (de)
JP (1) JP4783359B2 (de)
CN (2) CN102286483B (de)
AU (1) AU2005233326B2 (de)
CA (1) CA2560205A1 (de)
WO (1) WO2005100573A2 (de)

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CN101400694B (zh) 2005-12-01 2013-07-24 阿德库端木营养控股有限责任公司 用于工业生产柠檬酸的基因
ES2534282T3 (es) 2006-06-29 2015-04-21 Dsm Ip Assets B.V. Un método para lograr la expresión polipeptídica mejorada
EP2511372A1 (de) 2006-11-02 2012-10-17 DSM IP Assets B.V. Verbesserte Herstellung von sekretierten Proteinen durch filamentöse Pilze
CA2677568A1 (en) * 2007-02-15 2008-08-21 Dsm Ip Assets B.V. A recombinant host cell for the production of a compound of interest
MX2011005282A (es) * 2008-11-19 2011-09-06 Ct Investig Y Estudios Del Ipn Plantas y hongos transgenicos capaces de metabolizar fosfito como fuente de fosforo.
CN102741421B (zh) 2009-03-10 2015-03-25 帝斯曼知识产权资产管理有限公司 用于提高多肽产率的方法
JP2012524530A (ja) 2009-04-22 2012-10-18 ディーエスエム アイピー アセッツ ビー．ブイ． 対象組換えポリペプチドの産生方法
EP2456872B1 (de) 2009-07-22 2017-08-30 DSM IP Assets B.V. Verbesserte wirtszelle für die herstellung von relevanten produkten
BR112012011596B1 (pt) 2009-11-04 2018-10-02 Dsm Ip Assets Bv transformante de talaromyces, processos para a produção de um transformante de talaromyces, de um transformante múltiplo de talaromyces e de uma composição polipeptídica compreendendo uma ou mais celulases, e processos para a sacarificação de material lignocelulósico e para a preparação de um produto de fermentação
CN103347997A (zh) 2010-02-04 2013-10-09 帝斯曼知识产权资产管理有限公司 制备具有性周期的丝状真菌菌株的方法和制备有性杂交丝状真菌菌株的方法
CA2789301A1 (en) 2010-02-11 2011-08-18 Dsm Ip Assets B.V. Host cell capable of producing enzymes useful for degradation of lignocellulosic material
US8945898B2 (en) 2010-07-01 2015-02-03 Dsm Ip Assets B.V. Recombinant host cell with deficiency in non-ribosomal peptide synthase production
DK2683732T3 (en) 2011-03-11 2016-12-12 Dsm Ip Assets Bv Vector-host-system
IN2014DN10111A (de) 2012-06-19 2015-08-21 Dsm Ip Assets Bv
JP6468561B2 (ja) 2012-07-19 2019-02-13 ディーエスエム アイピー アセッツ ビー．ブイ．Ｄｓｍ Ｉｐ Ａｓｓｅｔｓ Ｂ．Ｖ． ＡｇｓＥ欠損株
DK3202900T3 (en) 2013-02-04 2019-04-08 Dsm Ip Assets Bv CARBOHYDRATE DEGRADING POLYPEPTIDE AND APPLICATIONS THEREOF
WO2014202622A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202624A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202620A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202621A1 (en) 2013-06-20 2014-12-24 Dsm Ip Assets B.V. Carbohydrate degrading polypeptide and uses thereof
WO2015024977A1 (en) 2013-08-20 2015-02-26 Lek Pharmaceuticals D.D. CELL CULTURE MEDIUM AND PROCESS FOR CONTROLLING α-AMIDATION AND/OR C-TERMINAL AMINO ACID CLEAVAGE OF POLYPEPTIDES
DK3036324T3 (en) * 2013-08-23 2019-04-01 Novozymes As Regulated PepC expression
MX370305B (es) 2013-12-02 2019-12-09 Dsm Ip Assets Bv Proteína estructurante de hielo.
MX2017015126A (es) 2015-06-02 2018-03-28 Dsm Ip Assets Bv Uso de proteina estructurante del hielo.
US11685911B2 (en) 2016-02-16 2023-06-27 Monaghan Mushroom S Group Fungal polypeptides having lysozyme activity
JP6959942B2 (ja) 2016-05-03 2021-11-05 ロンザ リミテッドLonza Limited タンパク質生成のための脂質代謝のモジュレーション
US10913938B2 (en) 2016-07-29 2021-02-09 Dsm Ip Assets B.V. Polypeptides having cellulolytic enhancing activity and uses thereof
JP7138425B2 (ja) * 2016-10-26 2022-09-16 キッコーマン株式会社 糸状菌の形質転換方法
EP3559222A1 (de) 2016-12-21 2019-10-30 DSM IP Assets B.V. Varianten lipolytischer enzyme
WO2018114938A1 (en) 2016-12-21 2018-06-28 Dsm Ip Assets B.V. Lipolytic enzyme variants
BR112019012559A2 (pt) 2016-12-21 2019-11-26 Dsm Ip Assets Bv variantes de enzima lipolítica
WO2018114912A1 (en) 2016-12-21 2018-06-28 Dsm Ip Assets B.V. Lipolytic enzyme variants
US20200063166A1 (en) 2017-03-13 2020-02-27 Dsm Ip Assets B.V. Zinc binuclear cluster transcriptional regulator-deficient strain
US20220112528A1 (en) 2019-01-11 2022-04-14 River Stone Biotech Aps Recombinant host cells with improved production of l-dopa, dopamine, s-noroclaurine or derivatives thereof
CA3141928A1 (en) 2019-05-27 2020-12-03 Octarine Bio Ivs Genetically modified host cells producing glycosylated cannabinoids
US20220331377A1 (en) 2019-09-09 2022-10-20 River Stone Biotech Isg Aps Delivery vehicle for in situ delivering of pharmaceutical agents
EP4055170A1 (de) 2019-11-04 2022-09-14 DSM IP Assets B.V. Niedrigvolumentransfektion
CN115074361B (zh) * 2021-03-12 2025-01-28 中国科学院天津工业生物技术研究所 真菌来源的强启动子及其应用
EP4334441A1 (de) 2021-05-07 2024-03-13 River Stone Biotech ApS Glykosylierte opioide
WO2024100063A1 (en) 2022-11-08 2024-05-16 River Stone Biotech Aps Genetically modified benzylisoquinoline alkaloid-producing host cells with modified efflux transporter gene expression

Citations (1)

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Publication number Priority date Publication date Assignee Title
WO1999032617A2 (en) * 1997-12-22 1999-07-01 Dsm N.V. Expression cloning in filamentous fungi

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WO1998046772A2 (en) 1997-04-11 1998-10-22 Dsm N.V. Gene conversion as a tool for the construction of recombinant industrial filamentous fungi
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WO1999032617A2 (en) * 1997-12-22 1999-07-01 Dsm N.V. Expression cloning in filamentous fungi

Non-Patent Citations (6)

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Title
DATABASE EMBL 20 September 2000 (2000-09-20), A. TSANG ET AL: "an_2027 Aspergillus niger, pYES (XhoI-EcoRi) Aspergillus niger cDNA clone 2027 3', mRNA sequence", XP002359964, retrieved from EBI, HINXTON , UK Database accession no. BE760662 *
FOWLER TIMOTHY ET AL: "The catR gene encoding a catalase from Aspergillus niger: Primary structure and elevated expression through increased gene copy number and use of a strong promoter", MOLECULAR MICROBIOLOGY, vol. 9, no. 5, 1993, pages 989 - 998, XP002041427, ISSN: 0950-382X *
KITAMOTO N ET AL: "Utilization of the TEF1-alpha gene (TEF1) promoter for expression of polygalacturonase genes, pgaA and pgaB, in Aspergillus oryzae", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, vol. 50, no. 1, July 1998 (1998-07-01), pages 85 - 92, XP002359962, ISSN: 0175-7598 *
PUNT P J ET AL: "INTRACELLULAR AND EXTRACELLULAR PRODUCTION OF PROTEINS IN ASPERGILLUS UNDER THE CONTROL OF EXPRESSION SIGNALS OF THE HIGHLY EXPRESSED ASPERGILLUS-NIDULANS GPD-A GENE", JOURNAL OF BIOTECHNOLOGY, vol. 17, no. 1, 1991, pages 19 - 33, XP002360233, ISSN: 0168-1656 *
ROBERTS I N ET AL: "EXPRESSION OF THE ESCHERICHIA COLI BETA-GLUCURONIDASE GENE IN INDUSTRIAL AND PHYTOPATHOGENIC FILAMENTOUS FUNGI", CURRENT GENETICS, NEW YORK, NY, US, vol. 15, no. 3, March 1989 (1989-03-01), pages 177 - 180, XP000995365, ISSN: 0172-8083 *
VERDOES JAN C ET AL: "The effect of multiple copies of the upstream region on expression of the Aspergillus niger glucoamylase-encoding gene", GENE: AN INTERNATIONAL JOURNAL ON GENES AND GENOMES, ELSEVIER, AMSTERDAM, NL, vol. 145, no. 2, 1994, pages 179 - 187, XP002194429, ISSN: 0378-1119 *

Also Published As

Publication number Publication date
CA2560205A1 (en) 2005-10-27
CN1942586B (zh) 2011-08-10
CN102286483A (zh) 2011-12-21
JP4783359B2 (ja) 2011-09-28
WO2005100573A3 (en) 2006-08-10
EP2345726A3 (de) 2011-12-14
US20120258489A1 (en) 2012-10-11
CN1942586A (zh) 2007-04-04
EP2345726A2 (de) 2011-07-20
JP2007532124A (ja) 2007-11-15
AU2005233326A1 (en) 2005-10-27
US20080305523A1 (en) 2008-12-11
US8211667B2 (en) 2012-07-03
EP1776461A2 (de) 2007-04-25
AU2005233326B2 (en) 2010-09-23
WO2005100573A9 (en) 2007-11-22
EP2345727A2 (de) 2011-07-20
CN102286483B (zh) 2014-06-04
WO2005100573A2 (en) 2005-10-27

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