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HK1093429A1 - Compounds effecting glucokinase - Google Patents

Compounds effecting glucokinase

Info

Publication number
HK1093429A1
HK1093429A1 HK06113586.7A HK06113586A HK1093429A1 HK 1093429 A1 HK1093429 A1 HK 1093429A1 HK 06113586 A HK06113586 A HK 06113586A HK 1093429 A1 HK1093429 A1 HK 1093429A1
Authority
HK
Hong Kong
Prior art keywords
glucokinase
compounds effecting
compounds
effecting glucokinase
effecting
Prior art date
Application number
HK06113586.7A
Other languages
English (en)
Inventor
Craig Johnstone
Roger James
Darren Mckerrecher
Scott Boyd
Peter Caulkett
Rodney Hargreaves
Clifford David Jones
Suzanne Bowker
Michael Howard Block
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of HK1093429A1 publication Critical patent/HK1093429A1/xx

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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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HK05108225A HK1076042A1 (en) 2001-08-17 2004-09-28 Compounds affecting glucokinase
HK05111879A HK1079692A1 (en) 2001-08-17 2004-09-28 Compounds effecting glucokinase
HK04107483A HK1064598A1 (en) 2001-08-17 2004-09-28 Compounds effecting glucokinase
HK06110673A HK1089960A1 (en) 2001-08-17 2006-09-25 Compound effecting glucokinase
HK06110762.9A HK1089966A1 (en) 2001-08-17 2006-09-27 Compounds effecting glucokinase
HK06110988A HK1090291A1 (en) 2001-08-17 2006-10-04 Compounds effecting glucokinase
HK06111020.5A HK1090292A1 (en) 2001-08-17 2006-10-05 Compounds effecting glukokinase
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HK05111879A HK1079692A1 (en) 2001-08-17 2004-09-28 Compounds effecting glucokinase
HK04107483A HK1064598A1 (en) 2001-08-17 2004-09-28 Compounds effecting glucokinase
HK06110673A HK1089960A1 (en) 2001-08-17 2006-09-25 Compound effecting glucokinase
HK06110762.9A HK1089966A1 (en) 2001-08-17 2006-09-27 Compounds effecting glucokinase
HK06110988A HK1090291A1 (en) 2001-08-17 2006-10-04 Compounds effecting glucokinase
HK06111020.5A HK1090292A1 (en) 2001-08-17 2006-10-05 Compounds effecting glukokinase
HK06111482.6A HK1090839A1 (en) 2001-08-17 2006-10-18 Compounds effecting glucokinase

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