MX2016013239A - Tratamiento de cancer utilizando receptor quimerico de antigeno anti-cd19. - Google Patents
Tratamiento de cancer utilizando receptor quimerico de antigeno anti-cd19.Info
- Publication number
- MX2016013239A MX2016013239A MX2016013239A MX2016013239A MX2016013239A MX 2016013239 A MX2016013239 A MX 2016013239A MX 2016013239 A MX2016013239 A MX 2016013239A MX 2016013239 A MX2016013239 A MX 2016013239A MX 2016013239 A MX2016013239 A MX 2016013239A
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- antigen
- cancer treatment
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- chemical
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- A61K40/00—Cellular immunotherapy
- A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
- A61K40/31—Chimeric antigen receptors [CAR]
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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Abstract
La invención proporciona composiciones y métodos para el tratamiento de enfermedades asociadas con la expresión de CD19, como por ejemplo mediante la administración de células T recombinantes que comprenden el CD19 CAR tal cual se describe en la presente, en combinación con un inhibidor de quinasa, como por ejemplo un inhibidor de quinasa descrito en la presente. La invención también proporciona kits y composiciones descritas en la presente.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461976396P | 2014-04-07 | 2014-04-07 | |
US201462007309P | 2014-06-03 | 2014-06-03 | |
US201462036493P | 2014-08-12 | 2014-08-12 | |
US201462076238P | 2014-11-06 | 2014-11-06 | |
US201462087888P | 2014-12-05 | 2014-12-05 | |
US201462097278P | 2014-12-29 | 2014-12-29 | |
PCT/US2015/024671 WO2015157252A1 (en) | 2014-04-07 | 2015-04-07 | Treatment of cancer using anti-cd19 chimeric antigen receptor |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2016013239A true MX2016013239A (es) | 2017-05-03 |
Family
ID=53008859
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016013239A MX2016013239A (es) | 2014-04-07 | 2015-04-07 | Tratamiento de cancer utilizando receptor quimerico de antigeno anti-cd19. |
MX2022010623A MX2022010623A (es) | 2014-04-07 | 2016-10-07 | Terapias de combinacion que comprenden un receptor quimerico de antigeno cd19 para el cancer. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022010623A MX2022010623A (es) | 2014-04-07 | 2016-10-07 | Terapias de combinacion que comprenden un receptor quimerico de antigeno cd19 para el cancer. |
Country Status (24)
Country | Link |
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US (2) | US10357514B2 (es) |
EP (3) | EP3129470B1 (es) |
JP (3) | JP6765966B2 (es) |
KR (3) | KR20240042250A (es) |
CN (2) | CN111514283A (es) |
AU (3) | AU2015244039B2 (es) |
CA (1) | CA2940671A1 (es) |
DK (2) | DK3888674T3 (es) |
ES (2) | ES2988631T3 (es) |
FI (1) | FI3888674T3 (es) |
HR (2) | HRP20240874T1 (es) |
HU (2) | HUE054588T2 (es) |
IL (4) | IL307423A (es) |
LT (2) | LT3129470T (es) |
MX (2) | MX2016013239A (es) |
MY (1) | MY191608A (es) |
PL (2) | PL3888674T3 (es) |
PT (2) | PT3888674T (es) |
RU (1) | RU2718542C2 (es) |
SG (2) | SG11201606909RA (es) |
SI (2) | SI3888674T1 (es) |
TW (1) | TWI753848B (es) |
WO (1) | WO2015157252A1 (es) |
ZA (1) | ZA201605657B (es) |
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WO2010099205A1 (en) * | 2009-02-24 | 2010-09-02 | The Trustees Of The University Of Pennsylvania | Methods for treating progressive multifocal leukoencephalopathy (pml) |
US10940169B2 (en) | 2015-11-30 | 2021-03-09 | Joseph E. Kovarik | Method for reducing the likelihood of developing cancer in an individual human being |
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US11998479B2 (en) | 2011-02-04 | 2024-06-04 | Seed Health, Inc. | Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure |
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US11951140B2 (en) | 2011-02-04 | 2024-04-09 | Seed Health, Inc. | Modulation of an individual's gut microbiome to address osteoporosis and bone disease |
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WO2014100615A1 (en) | 2012-12-20 | 2014-06-26 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
CN111139256A (zh) | 2013-02-20 | 2020-05-12 | 诺华股份有限公司 | 使用人源化抗EGFRvIII嵌合抗原受体治疗癌症 |
US9573988B2 (en) | 2013-02-20 | 2017-02-21 | Novartis Ag | Effective targeting of primary human leukemia using anti-CD123 chimeric antigen receptor engineered T cells |
EP3623380A1 (en) | 2013-03-15 | 2020-03-18 | Michael C. Milone | Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy |
UY35468A (es) | 2013-03-16 | 2014-10-31 | Novartis Ag | Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19 |
SG11201604815RA (en) | 2013-12-19 | 2016-07-28 | Novartis Ag | Human mesothelin chimeric antigen receptors and uses thereof |
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2015
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