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PT3129470T - Tratamento de cancro usando o recetor de antigénios quiméricos anti-cd19 - Google Patents

Tratamento de cancro usando o recetor de antigénios quiméricos anti-cd19

Info

Publication number
PT3129470T
PT3129470T PT157190430T PT15719043T PT3129470T PT 3129470 T PT3129470 T PT 3129470T PT 157190430 T PT157190430 T PT 157190430T PT 15719043 T PT15719043 T PT 15719043T PT 3129470 T PT3129470 T PT 3129470T
Authority
PT
Portugal
Prior art keywords
cancer
treatment
antigen receptor
chimeric antigen
chimeric
Prior art date
Application number
PT157190430T
Other languages
English (en)
Original Assignee
Univ Pennsylvania
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53008859&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT3129470(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Pennsylvania, Novartis Ag filed Critical Univ Pennsylvania
Publication of PT3129470T publication Critical patent/PT3129470T/pt

Links

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/00—Cellular immunotherapy
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    • A61K40/31—Chimeric antigen receptors [CAR]
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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    • C07K2317/565—Complementarity determining region [CDR]
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • C07—ORGANIC CHEMISTRY
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    • C07K2319/00—Fusion polypeptide
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  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • Hematology (AREA)
  • Oncology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PT157190430T 2014-04-07 2015-04-07 Tratamento de cancro usando o recetor de antigénios quiméricos anti-cd19 PT3129470T (pt)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201461976396P 2014-04-07 2014-04-07
US201462007309P 2014-06-03 2014-06-03
US201462036493P 2014-08-12 2014-08-12
US201462076238P 2014-11-06 2014-11-06
US201462087888P 2014-12-05 2014-12-05
US201462097278P 2014-12-29 2014-12-29

Publications (1)

Publication Number Publication Date
PT3129470T true PT3129470T (pt) 2021-07-13

Family

ID=53008859

Family Applications (2)

Application Number Title Priority Date Filing Date
PT211602032T PT3888674T (pt) 2014-04-07 2015-04-07 Tratamento de cancro usando o recetor de antigénios quiméricos anti-cd19
PT157190430T PT3129470T (pt) 2014-04-07 2015-04-07 Tratamento de cancro usando o recetor de antigénios quiméricos anti-cd19

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT211602032T PT3888674T (pt) 2014-04-07 2015-04-07 Tratamento de cancro usando o recetor de antigénios quiméricos anti-cd19

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US (2) US10357514B2 (pt)
EP (3) EP3129470B1 (pt)
JP (3) JP6765966B2 (pt)
KR (3) KR20240042250A (pt)
CN (2) CN111514283A (pt)
AU (3) AU2015244039B2 (pt)
CA (1) CA2940671A1 (pt)
DK (2) DK3888674T3 (pt)
ES (2) ES2988631T3 (pt)
FI (1) FI3888674T3 (pt)
HR (2) HRP20240874T1 (pt)
HU (2) HUE054588T2 (pt)
IL (4) IL307423A (pt)
LT (2) LT3129470T (pt)
MX (2) MX2016013239A (pt)
MY (1) MY191608A (pt)
PL (2) PL3888674T3 (pt)
PT (2) PT3888674T (pt)
RU (1) RU2718542C2 (pt)
SG (2) SG11201606909RA (pt)
SI (2) SI3888674T1 (pt)
TW (1) TWI753848B (pt)
WO (1) WO2015157252A1 (pt)
ZA (1) ZA201605657B (pt)

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WO2010099205A1 (en) * 2009-02-24 2010-09-02 The Trustees Of The University Of Pennsylvania Methods for treating progressive multifocal leukoencephalopathy (pml)
US10940169B2 (en) 2015-11-30 2021-03-09 Joseph E. Kovarik Method for reducing the likelihood of developing cancer in an individual human being
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UY35468A (es) 2013-03-16 2014-10-31 Novartis Ag Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
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