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HUE026613T2 - Halogénezett benzamid-származékok - Google Patents

Halogénezett benzamid-származékok

Info

Publication number
HUE026613T2
HUE026613T2 HUE05800142A HUE05800142A HUE026613T2 HU E026613 T2 HUE026613 T2 HU E026613T2 HU E05800142 A HUE05800142 A HU E05800142A HU E05800142 A HUE05800142 A HU E05800142A HU E026613 T2 HUE026613 T2 HU E026613T2
Authority
HU
Hungary
Prior art keywords
benzamide derivatives
halogenated benzamide
halogenated
derivatives
benzamide
Prior art date
Application number
HUE05800142A
Other languages
English (en)
Inventor
Jean Francois Rossignol
Original Assignee
Romark Laboratories Lc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Romark Laboratories Lc filed Critical Romark Laboratories Lc
Publication of HUE026613T2 publication Critical patent/HUE026613T2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
HUE05800142A 2004-09-09 2005-09-06 Halogénezett benzamid-származékok HUE026613T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60835404P 2004-09-09 2004-09-09

Publications (1)

Publication Number Publication Date
HUE026613T2 true HUE026613T2 (hu) 2016-06-28

Family

ID=36060542

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE05800142A HUE026613T2 (hu) 2004-09-09 2005-09-06 Halogénezett benzamid-származékok

Country Status (26)

Country Link
US (3) US7285567B2 (hu)
EP (1) EP1789040B1 (hu)
JP (1) JP4998852B2 (hu)
KR (1) KR101344984B1 (hu)
CN (1) CN101035531B (hu)
AP (1) AP2451A (hu)
AU (1) AU2005285157B2 (hu)
BR (1) BRPI0515089B8 (hu)
CA (1) CA2580347C (hu)
CY (1) CY1118689T1 (hu)
DK (1) DK1789040T3 (hu)
EA (1) EA012606B1 (hu)
ES (1) ES2559672T3 (hu)
HK (1) HK1106139A1 (hu)
HR (1) HRP20151439T1 (hu)
HU (1) HUE026613T2 (hu)
IL (2) IL181849A (hu)
ME (1) ME02370B (hu)
MX (1) MX2007002969A (hu)
PL (1) PL1789040T3 (hu)
PT (1) PT1789040E (hu)
RS (1) RS54453B1 (hu)
SI (1) SI1789040T1 (hu)
UA (1) UA90864C2 (hu)
WO (1) WO2006031566A2 (hu)
ZA (1) ZA200702066B (hu)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100369898C (zh) * 2002-02-12 2008-02-20 史密丝克莱恩比彻姆公司 用作p38抑制剂的烟酰胺衍生物
UA90864C2 (en) * 2004-09-09 2010-06-10 Ромарк Лебораториз, Л.К. Halogenated benzamide derivatives
AU2006235490A1 (en) * 2005-04-12 2006-10-19 Romark Laboratories, L.C. Methods for treating diseases through the function of molecular chaperones such as protein disulfide isomerases, pharmaceutical compositions comprising them, and screening methods for identifying therapeutic agents
DK1976516T3 (da) * 2006-01-09 2013-07-15 Romark Lab Lc Behandling af viral hepatitis
CA2695517C (en) 2007-08-03 2016-09-20 J. Edward Semple Alkylsulfonyl-substituted thiazolide compounds
PL2395840T3 (pl) 2009-02-13 2020-09-07 Romark Laboratories, L.C. Preparaty farmaceutyczne nitazoksanidu o kontrolowanym uwalnianiu
BRPI1010547A2 (pt) 2009-05-12 2019-04-09 Romark Laboratories L.C. composto, composição, e, métodos para tratar uma infecção viral, e rhabdovírus
MX341877B (es) 2009-06-26 2016-09-06 Romark Laboratories L C * Compuestos y métodos para tratar influenza.
CN102335171B (zh) * 2010-07-27 2013-09-11 中国农业科学院上海兽医研究所 一类n-(2-噻唑)苯甲酰胺衍生物的应用
JP6138764B2 (ja) 2011-05-16 2017-05-31 ロマーク ラボラトリーズ エル．シー． ウイルス性疾患、ガンおよび細胞内感染により引き起こされる疾患の予防および処置のためのチアゾリド化合物の使用
US9650369B2 (en) * 2012-09-28 2017-05-16 Xavier University Of Louisiana Anti-migration and anti-invasion thiazole analogs for treatment of cellular proliferative disease
JP6633092B2 (ja) 2014-11-11 2020-01-22 ロマーク ラボラトリーズ，リミティド カンパニー チゾキサニド、その類似体又は塩のプロドラッグを用いる組成物及び治療方法
CA3113354A1 (en) * 2016-03-31 2017-10-05 Romark Laboratories, L.C. Thiazolide compounds for treating viral infections
SG10202004425XA (en) 2016-04-11 2020-06-29 Genfit Methods of treatment for cholestatic and fibrotic diseases
US11173149B2 (en) 2017-04-18 2021-11-16 Romark Laboratories L.C. Inhibition of protein disulfide-isomerase A3
JP2023537237A (ja) 2020-07-20 2023-08-31 ロマーク ラボラトリーズ，リミティド カンパニー チゾキサニドおよび２－ヒドロキシ－ｎ－（５－クロロ－１，３－チアゾル－２－イル）ベンズアミド（ｒｍ－４８４８）とエタノールアミン、モルホリン、プロパノールアミン、ピペラジン、およびｎ－メチルピペラジンの結晶塩
BR112023003457A2 (pt) 2020-08-24 2023-05-02 Romark Laboratories Lc Uso de tiazolidas contra coronavírus
WO2022218239A1 (zh) * 2021-04-12 2022-10-20 杜心赟 新型噻唑类化合物及其制备方法和用途

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1276663A (en) * 1968-12-24 1972-06-07 Ici Ltd Stimulation of plant growth
CA946845A (en) * 1970-04-15 1974-05-07 Shell Internationale Research Maatschappij, N.V. Fungicidal compounds
GB1437800A (en) 1973-08-08 1976-06-03 Phavic Sprl Derivatives of 2-benzamido-5-nitro-thiazoles
US4315018A (en) 1978-12-07 1982-02-09 Rossignol Jean F Specific parasiticidal use of 2-benzamido-5-nitro-thiazole derivatives
JPS60205454A (ja) * 1984-03-29 1985-10-17 Mitsubishi Paper Mills Ltd 電子写真感光体
US5169846A (en) 1989-10-12 1992-12-08 Crooks Michael J Non-aqueous micellar solutions of anthelmintic benzimidazoles, closantel, or phenothiazine, and insect growth regulators
US5578612A (en) * 1990-10-15 1996-11-26 Pfizer Inc. Indole derivatives
US5387598A (en) 1994-04-13 1995-02-07 Rossignol; Jean-Francois Composition and galenic formulation suitable for combatting affections of the lower abdomen
KR100373081B1 (ko) * 1994-04-13 2003-02-25 로마크 레버러토리즈, 엘.씨. 벤즈아미드 유도체를 함유하는 의약 조성물
US5578621A (en) 1994-09-08 1996-11-26 Romark Lab Lc Benzamide derivatives
US5859038A (en) 1994-09-08 1999-01-12 Romark Laboratories, L.C. Method for treatment of helicobacter pylori infections
US5968961A (en) 1997-05-07 1999-10-19 Romark Laboratories, L.C. Pharmaceutical compositions of tizoxanide and nitazoxanide
US5856348A (en) 1994-09-08 1999-01-05 Romark Laboratories, L.C. Method for treatment of trematodes with pharmaceutical compositions of tizoxanide and nitazoxanide
MX9604483A (es) 1994-09-08 1998-02-28 Jean-Francois Rossignol Derivados de benzamida, composiciones que contienen dicho derivado y uso de las mismas.
US5965590A (en) 1994-09-08 1999-10-12 Romark Lab Lc Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide
DE19528046A1 (de) * 1994-11-21 1996-05-23 Bayer Ag Triazolyl-Derivate
US5935591A (en) * 1998-01-15 1999-08-10 Romark Laboratories, L.C. Method for treatment of equine protozoal myeloencephalitis with thiazolides
GB9823871D0 (en) * 1998-10-30 1998-12-23 Pharmacia & Upjohn Spa 2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents
CZ20023562A3 (cs) * 2000-04-28 2003-03-12 Sankyo Company, Limited PPAR gama modulátory
BR0111997A (pt) * 2000-07-14 2003-05-20 Breed Automotive Tech Retrator de cinto de segurança
EP1352650B1 (en) * 2000-12-18 2012-03-07 Institute of Medicinal Molecular Design, Inc. Inhibitors against the production and release of inflammatory cytokines
JP2003064056A (ja) * 2001-08-27 2003-03-05 Sankyo Co Ltd アミド誘導体
WO2003035602A1 (fr) * 2001-10-25 2003-05-01 Sankyo Company, Limited Modulateurs lipidiques
WO2003103665A1 (ja) * 2002-06-06 2003-12-18 株式会社医薬分子設計研究所 抗アレルギー薬
US6737382B1 (en) * 2002-10-23 2004-05-18 Nippon Soda Co. Ltd. Insecticidal aminothiazole derivatives
AU2005206571B8 (en) * 2004-01-23 2010-09-02 Amgen Inc. Compounds and methods of use
UA90864C2 (en) * 2004-09-09 2010-06-10 Ромарк Лебораториз, Л.К. Halogenated benzamide derivatives

Also Published As

Publication number Publication date
DK1789040T3 (en) 2016-02-01
HRP20151439T1 (hr) 2016-02-12
EA012606B1 (ru) 2009-10-30
US7550493B2 (en) 2009-06-23
AU2005285157B2 (en) 2009-07-16
WO2006031566A2 (en) 2006-03-23
HK1106139A1 (zh) 2008-03-07
ME02370B (me) 2016-06-20
PL1789040T3 (pl) 2016-04-29
EP1789040A2 (en) 2007-05-30
AU2005285157A1 (en) 2006-03-23
JP4998852B2 (ja) 2012-08-15
UA90864C2 (en) 2010-06-10
AP2451A (en) 2012-08-31
IL181849A (en) 2013-11-28
BRPI0515089B1 (pt) 2019-07-16
IL203061A (en) 2013-04-30
CA2580347C (en) 2013-12-10
ZA200702066B (en) 2008-08-27
EP1789040B1 (en) 2015-12-23
US20080097106A1 (en) 2008-04-24
CA2580347A1 (en) 2006-03-23
US20060089396A1 (en) 2006-04-27
CN101035531B (zh) 2013-01-02
US7285567B2 (en) 2007-10-23
KR20070052330A (ko) 2007-05-21
MX2007002969A (es) 2008-02-15
RS54453B1 (en) 2016-06-30
PT1789040E (pt) 2016-02-19
BRPI0515089A (pt) 2008-07-08
ES2559672T3 (es) 2016-02-15
SI1789040T1 (sl) 2016-02-29
BRPI0515089B8 (pt) 2021-05-25
CN101035531A (zh) 2007-09-12
IL181849A0 (en) 2007-07-04
EP1789040A4 (en) 2009-09-02
AP2007003950A0 (en) 2007-04-30
CY1118689T1 (el) 2017-07-12
US20080096941A1 (en) 2008-04-24
US7645783B2 (en) 2010-01-12
JP2008512474A (ja) 2008-04-24
EA200700432A1 (ru) 2007-10-26
WO2006031566A3 (en) 2006-06-08
KR101344984B1 (ko) 2013-12-24

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