[go: up one dir, main page]

HK1106139A1 - 鹵化苯甲酰胺衍生物 - Google Patents

鹵化苯甲酰胺衍生物

Info

Publication number
HK1106139A1
HK1106139A1 HK07111470.9A HK07111470A HK1106139A1 HK 1106139 A1 HK1106139 A1 HK 1106139A1 HK 07111470 A HK07111470 A HK 07111470A HK 1106139 A1 HK1106139 A1 HK 1106139A1
Authority
HK
Hong Kong
Prior art keywords
benzamide derivatives
halogenated benzamide
halogenated
derivatives
benzamide
Prior art date
Application number
HK07111470.9A
Other languages
English (en)
Inventor
Jean Francois Rossignol
Original Assignee
Romark Laboratories Lc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Romark Laboratories Lc filed Critical Romark Laboratories Lc
Publication of HK1106139A1 publication Critical patent/HK1106139A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/44Acylated amino or imino radicals
    • C07D277/46Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/44Acylated amino or imino radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
HK07111470.9A 2004-09-09 2007-10-24 鹵化苯甲酰胺衍生物 HK1106139A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60835404P 2004-09-09 2004-09-09
PCT/US2005/031868 WO2006031566A2 (en) 2004-09-09 2005-09-06 Halogenated benzamide derivatives

Publications (1)

Publication Number Publication Date
HK1106139A1 true HK1106139A1 (zh) 2008-03-07

Family

ID=36060542

Family Applications (1)

Application Number Title Priority Date Filing Date
HK07111470.9A HK1106139A1 (zh) 2004-09-09 2007-10-24 鹵化苯甲酰胺衍生物

Country Status (26)

Country Link
US (3) US7285567B2 (zh)
EP (1) EP1789040B1 (zh)
JP (1) JP4998852B2 (zh)
KR (1) KR101344984B1 (zh)
CN (1) CN101035531B (zh)
AP (1) AP2451A (zh)
AU (1) AU2005285157B2 (zh)
BR (1) BRPI0515089B8 (zh)
CA (1) CA2580347C (zh)
CY (1) CY1118689T1 (zh)
DK (1) DK1789040T3 (zh)
EA (1) EA012606B1 (zh)
ES (1) ES2559672T3 (zh)
HK (1) HK1106139A1 (zh)
HR (1) HRP20151439T1 (zh)
HU (1) HUE026613T2 (zh)
IL (2) IL181849A (zh)
ME (1) ME02370B (zh)
MX (1) MX2007002969A (zh)
PL (1) PL1789040T3 (zh)
PT (1) PT1789040E (zh)
RS (1) RS54453B1 (zh)
SI (1) SI1789040T1 (zh)
UA (1) UA90864C2 (zh)
WO (1) WO2006031566A2 (zh)
ZA (1) ZA200702066B (zh)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100369898C (zh) * 2002-02-12 2008-02-20 史密丝克莱恩比彻姆公司 用作p38抑制剂的烟酰胺衍生物
UA90864C2 (en) * 2004-09-09 2010-06-10 Ромарк Лебораториз, Л.К. Halogenated benzamide derivatives
AU2006235490A1 (en) * 2005-04-12 2006-10-19 Romark Laboratories, L.C. Methods for treating diseases through the function of molecular chaperones such as protein disulfide isomerases, pharmaceutical compositions comprising them, and screening methods for identifying therapeutic agents
DK1976516T3 (da) * 2006-01-09 2013-07-15 Romark Lab Lc Behandling af viral hepatitis
CA2695517C (en) 2007-08-03 2016-09-20 J. Edward Semple Alkylsulfonyl-substituted thiazolide compounds
PL2395840T3 (pl) 2009-02-13 2020-09-07 Romark Laboratories, L.C. Preparaty farmaceutyczne nitazoksanidu o kontrolowanym uwalnianiu
BRPI1010547A2 (pt) 2009-05-12 2019-04-09 Romark Laboratories L.C. composto, composição, e, métodos para tratar uma infecção viral, e rhabdovírus
MX341877B (es) 2009-06-26 2016-09-06 Romark Laboratories L C * Compuestos y métodos para tratar influenza.
CN102335171B (zh) * 2010-07-27 2013-09-11 中国农业科学院上海兽医研究所 一类n-(2-噻唑)苯甲酰胺衍生物的应用
JP6138764B2 (ja) 2011-05-16 2017-05-31 ロマーク ラボラトリーズ エル.シー. ウイルス性疾患、ガンおよび細胞内感染により引き起こされる疾患の予防および処置のためのチアゾリド化合物の使用
US9650369B2 (en) * 2012-09-28 2017-05-16 Xavier University Of Louisiana Anti-migration and anti-invasion thiazole analogs for treatment of cellular proliferative disease
JP6633092B2 (ja) 2014-11-11 2020-01-22 ロマーク ラボラトリーズ,リミティド カンパニー チゾキサニド、その類似体又は塩のプロドラッグを用いる組成物及び治療方法
CA3113354A1 (en) * 2016-03-31 2017-10-05 Romark Laboratories, L.C. Thiazolide compounds for treating viral infections
SG10202004425XA (en) 2016-04-11 2020-06-29 Genfit Methods of treatment for cholestatic and fibrotic diseases
US11173149B2 (en) 2017-04-18 2021-11-16 Romark Laboratories L.C. Inhibition of protein disulfide-isomerase A3
JP2023537237A (ja) 2020-07-20 2023-08-31 ロマーク ラボラトリーズ,リミティド カンパニー チゾキサニドおよび2-ヒドロキシ-n-(5-クロロ-1,3-チアゾル-2-イル)ベンズアミド(rm-4848)とエタノールアミン、モルホリン、プロパノールアミン、ピペラジン、およびn-メチルピペラジンの結晶塩
BR112023003457A2 (pt) 2020-08-24 2023-05-02 Romark Laboratories Lc Uso de tiazolidas contra coronavírus
WO2022218239A1 (zh) * 2021-04-12 2022-10-20 杜心赟 新型噻唑类化合物及其制备方法和用途

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1276663A (en) * 1968-12-24 1972-06-07 Ici Ltd Stimulation of plant growth
CA946845A (en) * 1970-04-15 1974-05-07 Shell Internationale Research Maatschappij, N.V. Fungicidal compounds
GB1437800A (en) 1973-08-08 1976-06-03 Phavic Sprl Derivatives of 2-benzamido-5-nitro-thiazoles
US4315018A (en) 1978-12-07 1982-02-09 Rossignol Jean F Specific parasiticidal use of 2-benzamido-5-nitro-thiazole derivatives
JPS60205454A (ja) * 1984-03-29 1985-10-17 Mitsubishi Paper Mills Ltd 電子写真感光体
US5169846A (en) 1989-10-12 1992-12-08 Crooks Michael J Non-aqueous micellar solutions of anthelmintic benzimidazoles, closantel, or phenothiazine, and insect growth regulators
US5578612A (en) * 1990-10-15 1996-11-26 Pfizer Inc. Indole derivatives
US5387598A (en) 1994-04-13 1995-02-07 Rossignol; Jean-Francois Composition and galenic formulation suitable for combatting affections of the lower abdomen
KR100373081B1 (ko) * 1994-04-13 2003-02-25 로마크 레버러토리즈, 엘.씨. 벤즈아미드 유도체를 함유하는 의약 조성물
US5578621A (en) 1994-09-08 1996-11-26 Romark Lab Lc Benzamide derivatives
US5859038A (en) 1994-09-08 1999-01-12 Romark Laboratories, L.C. Method for treatment of helicobacter pylori infections
US5968961A (en) 1997-05-07 1999-10-19 Romark Laboratories, L.C. Pharmaceutical compositions of tizoxanide and nitazoxanide
US5856348A (en) 1994-09-08 1999-01-05 Romark Laboratories, L.C. Method for treatment of trematodes with pharmaceutical compositions of tizoxanide and nitazoxanide
MX9604483A (es) 1994-09-08 1998-02-28 Jean-Francois Rossignol Derivados de benzamida, composiciones que contienen dicho derivado y uso de las mismas.
US5965590A (en) 1994-09-08 1999-10-12 Romark Lab Lc Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide
DE19528046A1 (de) * 1994-11-21 1996-05-23 Bayer Ag Triazolyl-Derivate
US5935591A (en) * 1998-01-15 1999-08-10 Romark Laboratories, L.C. Method for treatment of equine protozoal myeloencephalitis with thiazolides
GB9823871D0 (en) * 1998-10-30 1998-12-23 Pharmacia & Upjohn Spa 2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents
CZ20023562A3 (cs) * 2000-04-28 2003-03-12 Sankyo Company, Limited PPAR gama modulátory
BR0111997A (pt) * 2000-07-14 2003-05-20 Breed Automotive Tech Retrator de cinto de segurança
EP1352650B1 (en) * 2000-12-18 2012-03-07 Institute of Medicinal Molecular Design, Inc. Inhibitors against the production and release of inflammatory cytokines
JP2003064056A (ja) * 2001-08-27 2003-03-05 Sankyo Co Ltd アミド誘導体
WO2003035602A1 (fr) * 2001-10-25 2003-05-01 Sankyo Company, Limited Modulateurs lipidiques
WO2003103665A1 (ja) * 2002-06-06 2003-12-18 株式会社医薬分子設計研究所 抗アレルギー薬
US6737382B1 (en) * 2002-10-23 2004-05-18 Nippon Soda Co. Ltd. Insecticidal aminothiazole derivatives
AU2005206571B8 (en) * 2004-01-23 2010-09-02 Amgen Inc. Compounds and methods of use
UA90864C2 (en) * 2004-09-09 2010-06-10 Ромарк Лебораториз, Л.К. Halogenated benzamide derivatives

Also Published As

Publication number Publication date
DK1789040T3 (en) 2016-02-01
HRP20151439T1 (hr) 2016-02-12
EA012606B1 (ru) 2009-10-30
US7550493B2 (en) 2009-06-23
AU2005285157B2 (en) 2009-07-16
WO2006031566A2 (en) 2006-03-23
ME02370B (me) 2016-06-20
HUE026613T2 (hu) 2016-06-28
PL1789040T3 (pl) 2016-04-29
EP1789040A2 (en) 2007-05-30
AU2005285157A1 (en) 2006-03-23
JP4998852B2 (ja) 2012-08-15
UA90864C2 (en) 2010-06-10
AP2451A (en) 2012-08-31
IL181849A (en) 2013-11-28
BRPI0515089B1 (pt) 2019-07-16
IL203061A (en) 2013-04-30
CA2580347C (en) 2013-12-10
ZA200702066B (en) 2008-08-27
EP1789040B1 (en) 2015-12-23
US20080097106A1 (en) 2008-04-24
CA2580347A1 (en) 2006-03-23
US20060089396A1 (en) 2006-04-27
CN101035531B (zh) 2013-01-02
US7285567B2 (en) 2007-10-23
KR20070052330A (ko) 2007-05-21
MX2007002969A (es) 2008-02-15
RS54453B1 (en) 2016-06-30
PT1789040E (pt) 2016-02-19
BRPI0515089A (pt) 2008-07-08
ES2559672T3 (es) 2016-02-15
SI1789040T1 (sl) 2016-02-29
BRPI0515089B8 (pt) 2021-05-25
CN101035531A (zh) 2007-09-12
IL181849A0 (en) 2007-07-04
EP1789040A4 (en) 2009-09-02
AP2007003950A0 (en) 2007-04-30
CY1118689T1 (el) 2017-07-12
US20080096941A1 (en) 2008-04-24
US7645783B2 (en) 2010-01-12
JP2008512474A (ja) 2008-04-24
EA200700432A1 (ru) 2007-10-26
WO2006031566A3 (en) 2006-06-08
KR101344984B1 (ko) 2013-12-24

Similar Documents

Publication Publication Date Title
IL181849A0 (en) Halogenated benzamide derivatives
IL180481A0 (en) Aryl-pyridine derivatives
IL177968A0 (en) Tetrahydropyridoindole derivatives
IL181679A0 (en) Substituted aniline derivatives
HK1105971A1 (en) Pyrrazolo-pyrimidine derivatives
ZA200710817B (en) Benzamide derivatives and uses related thereto
ZA200703172B (en) Imidazo-benzodiazepine derivatives
IL181297A0 (en) Benzamide compounds
HK1100002A1 (en) 4-phenyl-pyrimidine-2-carbonitrile derivatives
HK1100775A1 (en) 4-Amino-5-cyanopyrimidine derivatives
GB0414272D0 (en) OsK1 derivatives
HUE041365T2 (hu) Demodikózis elleni szer
GB0500828D0 (en) Benzamide derivatives
GB0501146D0 (en) Novel benzamide derivatives
IL182001A0 (en) 2-acylaminothiazole derivatives
GB0526352D0 (en) Benzamide derivatives
ZA200701801B (en) Benzamide compounds
GB0526351D0 (en) Novel benzamide derivatives
GB0400310D0 (en) Anti-incrustation agent
GB0422648D0 (en) Benzamide compounds
GB0422397D0 (en) 3-Cyano-Quinoline derivatives
GB0405905D0 (en) Azaquinazoline derivatives
EP1712219A4 (en) AGENT DECREASING WRINKLES
EP1712217A4 (en) WRINKLE MITIGATION AGENT

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20210908