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DK4082530T5 - Proteasehæmmerholdige sammensætninger, sammensætninger omfattende samme og fremgangsmåder til fremstilling og anvendelse af samme - Google Patents

Proteasehæmmerholdige sammensætninger, sammensætninger omfattende samme og fremgangsmåder til fremstilling og anvendelse af samme Download PDF

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Publication number
DK4082530T5
DK4082530T5 DK22162188.1T DK22162188T DK4082530T5 DK 4082530 T5 DK4082530 T5 DK 4082530T5 DK 22162188 T DK22162188 T DK 22162188T DK 4082530 T5 DK4082530 T5 DK 4082530T5
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DK
Denmark
Prior art keywords
same
preparing
methods
compositions
protease inhibitors
Prior art date
Application number
DK22162188.1T
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English (en)
Other versions
DK4082530T3 (da
Inventor
Avraham Hershko
Miriam Kidron
Original Assignee
Oramed Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oramed Ltd filed Critical Oramed Ltd
Publication of DK4082530T3 publication Critical patent/DK4082530T3/da
Application granted granted Critical
Publication of DK4082530T5 publication Critical patent/DK4082530T5/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/26Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/56Protease inhibitors from plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4875Compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891Coated capsules; Multilayered drug free capsule shells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Botany (AREA)
  • Diabetes (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
DK22162188.1T 2012-02-01 2013-01-31 Proteasehæmmerholdige sammensætninger, sammensætninger omfattende samme og fremgangsmåder til fremstilling og anvendelse af samme DK4082530T5 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261632868P 2012-02-01 2012-02-01
US201261634753P 2012-03-06 2012-03-06
EP13744410.5A EP2814504B1 (en) 2012-02-01 2013-01-31 Protease inhibitor-containing compositions, compositions comprising same, and methods for producing and using same

Publications (2)

Publication Number Publication Date
DK4082530T3 DK4082530T3 (da) 2024-05-06
DK4082530T5 true DK4082530T5 (da) 2024-07-22

Family

ID=48904507

Family Applications (2)

Application Number Title Priority Date Filing Date
DK22162188.1T DK4082530T5 (da) 2012-02-01 2013-01-31 Proteasehæmmerholdige sammensætninger, sammensætninger omfattende samme og fremgangsmåder til fremstilling og anvendelse af samme
DK13744410.5T DK2814504T3 (da) 2012-02-01 2013-01-31 Protease inhibitor indeholdende sammensætninger, sammensætninger omfattende samme og metoder til fremstilling og brug af samme

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK13744410.5T DK2814504T3 (da) 2012-02-01 2013-01-31 Protease inhibitor indeholdende sammensætninger, sammensætninger omfattende samme og metoder til fremstilling og brug af samme

Country Status (9)

Country Link
US (4) US10342764B2 (da)
EP (2) EP4082530B1 (da)
JP (3) JP6567827B2 (da)
CN (3) CN104244969A (da)
DK (2) DK4082530T5 (da)
ES (1) ES2912138T3 (da)
HK (1) HK1200727A1 (da)
HU (1) HUE066433T2 (da)
WO (1) WO2013114369A1 (da)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180228621A1 (en) 2004-08-09 2018-08-16 Mark A. Reiley Apparatus, systems, and methods for the fixation or fusion of bone
CA2621577C (en) * 2005-09-06 2013-12-24 Oramed Pharmaceuticals, Inc. Methods and compositions for oral administration of proteins
JP5395160B2 (ja) 2008-03-26 2014-01-22 オラムド エルティーディー. タンパク質の経口投与方法及び組成物
BRPI0908292B1 (pt) 2008-05-05 2022-09-20 Oramed Ltd Métodos e composições para administração oral de exenatida
EP2800579B1 (en) 2012-01-03 2017-08-30 Oramed Ltd. Capsules containing oil-based liquid compositions of combined therapeutic agents for treating diabetes
DK4082530T5 (da) 2012-02-01 2024-07-22 Oramed Ltd Proteasehæmmerholdige sammensætninger, sammensætninger omfattende samme og fremgangsmåder til fremstilling og anvendelse af samme
US10363140B2 (en) 2012-03-09 2019-07-30 Si-Bone Inc. Systems, device, and methods for joint fusion
IN2014DN06946A (da) 2012-03-09 2015-04-10 Si Bone Inc
EP3479778B1 (en) 2012-05-04 2020-09-16 SI-Bone, Inc. Fenestrated implant
EP2941267B1 (en) 2013-01-03 2022-11-16 Oramed Ltd. Compositions for use in treating nafld
US9936983B2 (en) 2013-03-15 2018-04-10 Si-Bone Inc. Implants for spinal fixation or fusion
US11147688B2 (en) 2013-10-15 2021-10-19 Si-Bone Inc. Implant placement
WO2016044731A1 (en) 2014-09-18 2016-03-24 Si-Bone Inc. Implants for bone fixation or fusion
EP3782586A1 (en) 2014-09-18 2021-02-24 SI-Bone, Inc. Matrix implant
CN105343184A (zh) * 2015-12-01 2016-02-24 无限极(中国)有限公司 一种组合物及其应用
WO2017161184A1 (en) * 2016-03-16 2017-09-21 Amidebio, Llc Methods for producing peptides and uses thereof
EP3687422A4 (en) 2017-09-26 2021-09-22 SI-Bone, Inc. SYSTEMS AND PROCESSES FOR DECORTICATION OF THE SACROILIAC JOINT
MX2020013296A (es) * 2018-06-11 2021-05-27 Oramed Ltd Composiciones que contienen inhibidor de proteasa recombinante, metodos para producir las mismas y usos de las mismas.
US11369419B2 (en) 2019-02-14 2022-06-28 Si-Bone Inc. Implants for spinal fixation and or fusion
AU2020223180A1 (en) 2019-02-14 2021-07-22 Si-Bone Inc. Implants for spinal fixation and or fusion
JP2023505055A (ja) 2019-11-27 2023-02-08 エスアイ-ボーン・インコーポレイテッド 骨安定インプラント及び仙腸関節を横切る配置方法
AU2020402850A1 (en) 2019-12-09 2022-06-09 Si-Bone Inc. Sacro-iliac joint stabilizing implants and methods of implantation
WO2022125619A1 (en) 2020-12-09 2022-06-16 Si-Bone Inc. Sacro-iliac joint stabilizing implants and methods of implantation
WO2023017537A1 (en) * 2021-08-12 2023-02-16 Celagenex Research (India) Pvt. Ltd. Oral algal oil based gastro-intestinal tract permeable peptide composition
CN117186237A (zh) * 2022-05-29 2023-12-08 中国医学科学院药物研究所 一种含有糜蛋白酶抑制肽的胰岛素杂交肽及其应用

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL68769A (en) 1983-05-23 1986-02-28 Hadassah Med Org Pharmaceutical compositions containing insulin for oral administration
JPS6350793A (ja) 1986-08-20 1988-03-03 株式会社東芝 高速増殖炉の崩壊熱除去システム
US5034415A (en) 1987-08-07 1991-07-23 Century Laboratories, Inc. Treatment of diabetes mellitus
DE68909135T2 (de) 1988-07-21 1994-04-07 Hoffmann La Roche Insulinzubereitung.
JPH02250823A (ja) 1989-03-24 1990-10-08 Tsumura & Co マイクロカプセル剤およびその製造方法
GB9007052D0 (en) 1990-03-29 1990-05-30 Skua Investments Ltd Pharmaceutical formulations
US5206219A (en) 1991-11-25 1993-04-27 Applied Analytical Industries, Inc. Oral compositions of proteinaceous medicaments
JPH06145198A (ja) * 1992-03-30 1994-05-24 Shokuhin Sangyo High Separeeshiyon Syst Gijutsu Kenkyu Kumiai 大豆トリプシンインヒビターの製造方法
US6692766B1 (en) 1994-06-15 2004-02-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Controlled release oral drug delivery system
US5824638A (en) 1995-05-22 1998-10-20 Shire Laboratories, Inc. Oral insulin delivery
IL114673A (en) 1995-07-19 2000-12-06 Hadasit Med Res Service Pharmaceutical compositions containing protein for oral administration
JPH09208485A (ja) 1996-01-31 1997-08-12 Teijin Ltd ペプチド・蛋白質性薬物の水難溶性組成物
ATE493998T1 (de) 1996-08-08 2011-01-15 Amylin Pharmaceuticals Inc Pharmazeutische zusammensetzung mit einem exendin-4-peptid
JPH10330287A (ja) 1997-03-31 1998-12-15 Nippon Suisan Kaisha Ltd 多価不飽和脂肪酸からなる消化管吸収促進剤およびそれを含有する薬剤
JP2000128805A (ja) 1998-10-27 2000-05-09 Nippon Suisan Kaisha Ltd 多価不飽和脂肪酸および高分子ゲルからなる経粘膜吸収促進剤及びそれを含有する薬剤
US6267985B1 (en) 1999-06-30 2001-07-31 Lipocine Inc. Clear oil-containing pharmaceutical compositions
US6761903B2 (en) 1999-06-30 2004-07-13 Lipocine, Inc. Clear oil-containing pharmaceutical compositions containing a therapeutic agent
JP2001240558A (ja) 2000-02-29 2001-09-04 Nippon Suisan Kaisha Ltd 多価不飽和脂肪酸を経粘膜吸収促進剤として含有する固形製剤。
US6673574B2 (en) 2000-11-30 2004-01-06 Unigene Laboratories Inc. Oral delivery of peptides using enzyme-cleavable membrane translocators
KR20010069322A (ko) 2001-03-08 2001-07-25 서종수 휴대형정보단말기 또는 화상이동통신장치를 이용한전자경매방법
KR20010069433A (ko) 2001-03-22 2001-07-25 김윤완 노루궁뎅이버섯을 이용한 건강 보조 식품
CN1160122C (zh) * 2001-04-20 2004-08-04 清华大学 一种制备口服胰岛素油相制剂的方法
CN1741805A (zh) 2001-07-18 2006-03-01 索莱有限责任公司 高蛋白质鲍曼-比尔克抑制剂浓缩物及其生产方法
US20030198666A1 (en) 2002-01-07 2003-10-23 Richat Abbas Oral insulin therapy
JP4165329B2 (ja) * 2002-07-31 2008-10-15 不二製油株式会社 大豆ホエー分画物の製造法
US7767828B2 (en) 2003-11-12 2010-08-03 Phenomix Corporation Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
US20060286129A1 (en) 2003-12-19 2006-12-21 Emisphere Technologies, Inc. Oral GLP-1 formulations
US20050143303A1 (en) 2003-12-26 2005-06-30 Nastech Pharmaceutical Company Inc. Intranasal administration of glucose-regulating peptides
US8076288B2 (en) 2004-02-11 2011-12-13 Amylin Pharmaceuticals, Inc. Hybrid polypeptides having glucose lowering activity
AU2005329255B2 (en) 2004-04-15 2010-09-30 Chiasma, Inc. Compositions capable of facilitating penetration across a biological barrier
WO2006014673A2 (en) 2004-07-19 2006-02-09 Nobex Corporation Insulin-oligomer conjugates, formulations and uses thereof
US20060046962A1 (en) 2004-08-25 2006-03-02 Aegis Therapeutics Llc Absorption enhancers for drug administration
WO2006025882A2 (en) 2004-08-25 2006-03-09 The Uab Research Foundation Absorption enhancers for drug administration
WO2006057551A1 (en) 2004-11-26 2006-06-01 N.V. Nutricia Infant nutrition with protease inhibitor
CA2621577C (en) 2005-09-06 2013-12-24 Oramed Pharmaceuticals, Inc. Methods and compositions for oral administration of proteins
US20070086972A1 (en) 2005-09-12 2007-04-19 Jacob Birnbaum Hair growth compositions and methods for treating hair loss or related conditions
US20070077283A1 (en) 2005-09-30 2007-04-05 Nastech Pharmaceutical Company Inc. Method of enhancing transmucosal delivery of therapeutic compounds
CN101095942B (zh) 2006-06-30 2011-11-16 北京民海生物科技有限公司 一种包含稳定剂的Exendin-4注射剂药物配方
JP5395160B2 (ja) * 2008-03-26 2014-01-22 オラムド エルティーディー. タンパク質の経口投与方法及び組成物
BRPI0908292B1 (pt) 2008-05-05 2022-09-20 Oramed Ltd Métodos e composições para administração oral de exenatida
CA2729296A1 (en) 2008-06-17 2010-01-28 Richard D. Dimarchi Gip-based mixed agonists for treatment of metabolic disorders and obesity
US9186412B2 (en) 2008-08-18 2015-11-17 Entera Bio Ltd. Methods and compositions for oral administration of insulin
EP2785730A1 (en) * 2009-12-30 2014-10-08 Solae, LLC Method for recovering kunitz-trypsin inhibitor proteins from a soy processing stream
EP2800579B1 (en) 2012-01-03 2017-08-30 Oramed Ltd. Capsules containing oil-based liquid compositions of combined therapeutic agents for treating diabetes
DK4082530T5 (da) 2012-02-01 2024-07-22 Oramed Ltd Proteasehæmmerholdige sammensætninger, sammensætninger omfattende samme og fremgangsmåder til fremstilling og anvendelse af samme
EP2941267B1 (en) 2013-01-03 2022-11-16 Oramed Ltd. Compositions for use in treating nafld
MX2020013296A (es) 2018-06-11 2021-05-27 Oramed Ltd Composiciones que contienen inhibidor de proteasa recombinante, metodos para producir las mismas y usos de las mismas.

Also Published As

Publication number Publication date
DK2814504T3 (da) 2022-05-02
JP2015510506A (ja) 2015-04-09
US20140377344A1 (en) 2014-12-25
US20210369626A1 (en) 2021-12-02
US20190321303A1 (en) 2019-10-24
EP2814504B1 (en) 2022-03-16
US10342764B2 (en) 2019-07-09
US10933022B2 (en) 2021-03-02
DK4082530T3 (da) 2024-05-06
US20240358647A1 (en) 2024-10-31
CN112755002A (zh) 2021-05-07
JP2020117518A (ja) 2020-08-06
ES2912138T3 (es) 2022-05-24
HUE066433T2 (hu) 2024-08-28
EP2814504A4 (en) 2015-10-14
CN113769074A (zh) 2021-12-10
JP6567827B2 (ja) 2019-08-28
EP2814504A1 (en) 2014-12-24
HK1200727A1 (en) 2015-08-14
CN104244969A (zh) 2014-12-24
WO2013114369A1 (en) 2013-08-08
EP4082530A1 (en) 2022-11-02
EP4082530B1 (en) 2024-04-10
JP7064226B2 (ja) 2022-05-10
JP2018104443A (ja) 2018-07-05

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