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DK3008168T3 - Sc-celler og sammensætninger og fremgangsmåde til dannelse deraf - Google Patents

Sc-celler og sammensætninger og fremgangsmåde til dannelse deraf Download PDF

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Publication number
DK3008168T3
DK3008168T3 DK14819763.5T DK14819763T DK3008168T3 DK 3008168 T3 DK3008168 T3 DK 3008168T3 DK 14819763 T DK14819763 T DK 14819763T DK 3008168 T3 DK3008168 T3 DK 3008168T3
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Denmark
Prior art keywords
creating
compositions
cells
procedure
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DK14819763.5T
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English (en)
Inventor
Quinn P Peterson
Felicia J Pagliuca
Douglas A Melton
Jeffrey R Millman
Alireza Rezania
Benjamin Fryer
Michael Saris Segal
Mads Gürtler
Original Assignee
Harvard College
Janssen Biotech Inc
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C12N5/0678—Stem cells; Progenitor cells; Precursor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/39—Pancreas; Islets of Langerhans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • C12N2501/30—Hormones
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    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells

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  • Diabetes (AREA)
  • General Engineering & Computer Science (AREA)
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  • Developmental Biology & Embryology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Transplantation (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK14819763.5T 2013-06-11 2014-06-11 Sc-celler og sammensætninger og fremgangsmåde til dannelse deraf DK3008168T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361833898P 2013-06-11 2013-06-11
US201461972212P 2014-03-28 2014-03-28
PCT/US2014/041988 WO2015002724A2 (en) 2013-06-11 2014-06-11 SC-β CELLS AND COMPOSITIONS AND METHODS FOR GENERATING THE SAME

Publications (1)

Publication Number Publication Date
DK3008168T3 true DK3008168T3 (da) 2020-05-04

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DK14819763.5T DK3008168T3 (da) 2013-06-11 2014-06-11 Sc-celler og sammensætninger og fremgangsmåde til dannelse deraf

Country Status (17)

Country Link
US (16) US20170029778A1 (da)
EP (4) EP3008168B1 (da)
JP (7) JP6514689B2 (da)
KR (11) KR102361924B1 (da)
CN (4) CN110551678B (da)
AU (6) AU2014278178B2 (da)
BR (2) BR112015030946A8 (da)
CA (2) CA2915091A1 (da)
DE (2) DE202014011287U1 (da)
DK (1) DK3008168T3 (da)
GB (3) GB2549822B (da)
HK (1) HK1257187B (da)
MX (2) MX2015017103A (da)
PH (1) PH12015502767A1 (da)
RU (2) RU2016100219A (da)
SG (3) SG11201510177WA (da)
WO (2) WO2014201167A1 (da)

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SG10201608914WA (en) 2011-12-22 2016-12-29 Janssen Biotech Inc Differentiation of human embryonic stem cells into single hormonal insulin positive cells
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KR102361924B1 (ko) 2013-06-11 2022-02-14 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 SC-β 세포 및 조성물 그리고 그 생성 방법
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US20160175363A1 (en) * 2014-12-18 2016-06-23 President And Fellows Of Harvard College Methods for generating stem cell-derived beta cells and uses thereof
ES2985135T3 (es) 2014-12-18 2024-11-04 Harvard College Procedimientos para generar células ß derivadas de células madre y usos de las mismas
CN113234661A (zh) 2014-12-18 2021-08-10 哈佛学院校长同事会 干细胞来源的β细胞的产生方法及其使用方法
EP3234111A1 (en) 2014-12-19 2017-10-25 Regeneron Pharmaceuticals, Inc. Stem cells for modeling type 2 diabetes
EP3286563B1 (en) 2015-04-23 2022-11-02 The Regents of The University of California Controlled induction of human pancreatic progenitors produces functional beta-like cells
DK3285572T3 (da) * 2015-04-24 2021-03-01 Univ Copenhagen Fremgangsmåde til fremstilling af insulinproducerende celler
EP3286300B1 (en) 2015-04-24 2020-10-21 University of Copenhagen Isolation of bona fide pancreatic progenitor cells
EP3328404A4 (en) * 2015-07-27 2018-12-26 The Regents of The University of California Methods and compositions for producing pancreatic beta cells
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EP3386543B1 (en) 2015-11-10 2021-07-21 City of Hope Conditioning regimens and methods for inducing mixed chimerism
WO2017116569A1 (en) * 2015-12-31 2017-07-06 City Of Hope Methods for treating diabetes
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JP2019507609A (ja) * 2016-03-02 2019-03-22 フリークエンシー セラピューティクス インコーポレイテッド ＷＮＴおよびＴＧＦ−β阻害を用いる、前庭幹細胞の制御された増殖／内耳有毛細胞の発生のための方法
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