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AP2451A - Halogenated benzamide derivatives - Google Patents

Halogenated benzamide derivatives

Info

Publication number
AP2451A
AP2451A AP2007003950A AP2007003950A AP2451A AP 2451 A AP2451 A AP 2451A AP 2007003950 A AP2007003950 A AP 2007003950A AP 2007003950 A AP2007003950 A AP 2007003950A AP 2451 A AP2451 A AP 2451A
Authority
AP
ARIPO
Prior art keywords
benzamide derivatives
halogenated benzamide
halogenated
derivatives
benzamide
Prior art date
Application number
AP2007003950A
Other languages
English (en)
Other versions
AP2007003950A0 (en
Inventor
Jean-Francois Rossignol
Original Assignee
Romark Lab Lc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Romark Lab Lc filed Critical Romark Lab Lc
Publication of AP2007003950A0 publication Critical patent/AP2007003950A0/xx
Application granted granted Critical
Publication of AP2451A publication Critical patent/AP2451A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
AP2007003950A 2004-09-09 2005-09-06 Halogenated benzamide derivatives AP2451A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60835404P 2004-09-09 2004-09-09
PCT/US2005/031868 WO2006031566A2 (en) 2004-09-09 2005-09-06 Halogenated benzamide derivatives

Publications (2)

Publication Number Publication Date
AP2007003950A0 AP2007003950A0 (en) 2007-04-30
AP2451A true AP2451A (en) 2012-08-31

Family

ID=36060542

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2007003950A AP2451A (en) 2004-09-09 2005-09-06 Halogenated benzamide derivatives

Country Status (26)

Country Link
US (3) US7285567B2 (pt)
EP (1) EP1789040B1 (pt)
JP (1) JP4998852B2 (pt)
KR (1) KR101344984B1 (pt)
CN (1) CN101035531B (pt)
AP (1) AP2451A (pt)
AU (1) AU2005285157B2 (pt)
BR (1) BRPI0515089B8 (pt)
CA (1) CA2580347C (pt)
CY (1) CY1118689T1 (pt)
DK (1) DK1789040T3 (pt)
EA (1) EA012606B1 (pt)
ES (1) ES2559672T3 (pt)
HK (1) HK1106139A1 (pt)
HR (1) HRP20151439T1 (pt)
HU (1) HUE026613T2 (pt)
IL (2) IL181849A (pt)
ME (1) ME02370B (pt)
MX (1) MX2007002969A (pt)
PL (1) PL1789040T3 (pt)
PT (1) PT1789040E (pt)
RS (1) RS54453B1 (pt)
SI (1) SI1789040T1 (pt)
UA (1) UA90864C2 (pt)
WO (1) WO2006031566A2 (pt)
ZA (1) ZA200702066B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE375980T1 (de) * 2002-02-12 2007-11-15 Smithkline Beecham Corp Nicotinamide und deren verwendung als p38 inhibitoren
UA90864C2 (en) * 2004-09-09 2010-06-10 Ромарк Лебораториз, Л.К. Halogenated benzamide derivatives
EP1871365A2 (en) * 2005-04-12 2008-01-02 Romark Laboratories, L.C. Methods for treating diseases through inhibition the function of molecular chaperones such as protein disulfide isomerases , pharmaceutical compositions comprising them, and screening methods for identifying therapeutic agents
US8633230B2 (en) * 2006-01-09 2014-01-21 Jean-Francois Rossignol Viral hepatitis treatment
CA2695517C (en) 2007-08-03 2016-09-20 J. Edward Semple Alkylsulfonyl-substituted thiazolide compounds
ES2797493T3 (es) 2009-02-13 2020-12-02 Romark Laboratories Lc Formulaciones farmacéuticas de liberación controlada de nitazoxanida
NZ596538A (en) * 2009-05-12 2014-04-30 Romark Lab Lc Haloalkyl heteroaryl benzamide compounds
BR122020003634B8 (pt) * 2009-06-26 2021-07-27 Romark Laboratories Lc uso de nitazoxanida, tizoxanida ou sal farmaceuticalmente aceitável do mesmo no tratamento de uma doença semelhante a influenza
CN102335171B (zh) * 2010-07-27 2013-09-11 中国农业科学院上海兽医研究所 一类n-(2-噻唑)苯甲酰胺衍生物的应用
JP6138764B2 (ja) 2011-05-16 2017-05-31 ロマーク ラボラトリーズ エル．シー． ウイルス性疾患、ガンおよび細胞内感染により引き起こされる疾患の予防および処置のためのチアゾリド化合物の使用
WO2014052831A1 (en) * 2012-09-28 2014-04-03 Xavier University Of Louisiana Anti-migration and anti-invasion thiazole analogs for treatment of cellular proliferative disease
MX2017006083A (es) 2014-11-11 2017-11-08 Romark Laboratories Lc Composicones y metodos de tratamiento con profarmacos de tizoxanida, un analogo o sal de la misma.
LT3436074T (lt) 2016-03-31 2020-09-25 Romark Laboratories, L.C. Tiazolido junginiai, skirti virusinių infekcijų gydymui
DK3777855T3 (da) 2016-04-11 2023-01-09 Genfit Fremgangsmåder til behandling af fibrotiske sygdomme
US11173149B2 (en) 2017-04-18 2021-11-16 Romark Laboratories L.C. Inhibition of protein disulfide-isomerase A3
EP4182304A1 (en) 2020-07-20 2023-05-24 Romark Laboratories, L.C. Crystalline salts of tizoxanide and 2-hydroxy-n-(5-chloro-1,3-thiazol-2-yl)benzamide (rm-4848) with ethanolamine, morpholine, propanolamine, piperazine and n-methylpiperazine
CN116367892A (zh) 2020-08-24 2023-06-30 罗马克实验室有限公司 噻唑化物抗冠状病毒的用途
CN115197164A (zh) * 2021-04-12 2022-10-18 杜心赟 新型噻唑类化合物及其制备方法和用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000026202A1 (en) * 1998-10-30 2000-05-11 Pharmacia & Upjohn S.P.A. 2-amino-thiazole derivatives, process for their preparation, and their use as antitumor agents
EP1277729A1 (en) * 2000-04-28 2003-01-22 Sankyo Company, Limited Ppar (gamma) modulators
WO2003103665A1 (ja) * 2002-06-06 2003-12-18 株式会社医薬分子設計研究所 抗アレルギー薬

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GB1276663A (en) * 1968-12-24 1972-06-07 Ici Ltd Stimulation of plant growth
PH9683A (en) * 1970-04-15 1976-02-10 P Haken Carboxamide derivatives and the use as fungicides thereof
GB1437800A (en) 1973-08-08 1976-06-03 Phavic Sprl Derivatives of 2-benzamido-5-nitro-thiazoles
US4315018A (en) 1978-12-07 1982-02-09 Rossignol Jean F Specific parasiticidal use of 2-benzamido-5-nitro-thiazole derivatives
JPS60205454A (ja) * 1984-03-29 1985-10-17 Mitsubishi Paper Mills Ltd 電子写真感光体
US5169846A (en) 1989-10-12 1992-12-08 Crooks Michael J Non-aqueous micellar solutions of anthelmintic benzimidazoles, closantel, or phenothiazine, and insect growth regulators
US5578612A (en) * 1990-10-15 1996-11-26 Pfizer Inc. Indole derivatives
US5578621A (en) 1994-09-08 1996-11-26 Romark Lab Lc Benzamide derivatives
AP645A (en) * 1994-04-13 1998-04-24 Romark Laboratories Lc Benzamine derivative, compositions containing said derivative and use thereof.
US5387598A (en) 1994-04-13 1995-02-07 Rossignol; Jean-Francois Composition and galenic formulation suitable for combatting affections of the lower abdomen
US5859038A (en) 1994-09-08 1999-01-12 Romark Laboratories, L.C. Method for treatment of helicobacter pylori infections
MX9604483A (es) 1994-09-08 1998-02-28 Jean-Francois Rossignol Derivados de benzamida, composiciones que contienen dicho derivado y uso de las mismas.
US5856348A (en) 1994-09-08 1999-01-05 Romark Laboratories, L.C. Method for treatment of trematodes with pharmaceutical compositions of tizoxanide and nitazoxanide
US5968961A (en) 1997-05-07 1999-10-19 Romark Laboratories, L.C. Pharmaceutical compositions of tizoxanide and nitazoxanide
US5965590A (en) 1994-09-08 1999-10-12 Romark Lab Lc Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide
DE19528046A1 (de) * 1994-11-21 1996-05-23 Bayer Ag Triazolyl-Derivate
US5935591A (en) * 1998-01-15 1999-08-10 Romark Laboratories, L.C. Method for treatment of equine protozoal myeloencephalitis with thiazolides
BR0111997A (pt) * 2000-07-14 2003-05-20 Breed Automotive Tech Retrator de cinto de segurança
KR20090090406A (ko) * 2000-12-18 2009-08-25 가부시키가이샤 이야쿠 분지 셋케이 겐쿠쇼 염증성 사이토카인 생산 유리 억제제
JP2003064056A (ja) * 2001-08-27 2003-03-05 Sankyo Co Ltd アミド誘導体
WO2003035602A1 (fr) * 2001-10-25 2003-05-01 Sankyo Company, Limited Modulateurs lipidiques
US6737382B1 (en) * 2002-10-23 2004-05-18 Nippon Soda Co. Ltd. Insecticidal aminothiazole derivatives
EA011402B1 (ru) * 2004-01-23 2009-02-27 Эмджен Инк. Азотсодержащие гетероциклические производные и их фармацевтические применения
UA90864C2 (en) * 2004-09-09 2010-06-10 Ромарк Лебораториз, Л.К. Halogenated benzamide derivatives

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000026202A1 (en) * 1998-10-30 2000-05-11 Pharmacia & Upjohn S.P.A. 2-amino-thiazole derivatives, process for their preparation, and their use as antitumor agents
EP1277729A1 (en) * 2000-04-28 2003-01-22 Sankyo Company, Limited Ppar (gamma) modulators
WO2003103665A1 (ja) * 2002-06-06 2003-12-18 株式会社医薬分子設計研究所 抗アレルギー薬

Also Published As

Publication number Publication date
SI1789040T1 (sl) 2016-02-29
US20080096941A1 (en) 2008-04-24
BRPI0515089A (pt) 2008-07-08
BRPI0515089B8 (pt) 2021-05-25
KR20070052330A (ko) 2007-05-21
WO2006031566A2 (en) 2006-03-23
CA2580347C (en) 2013-12-10
KR101344984B1 (ko) 2013-12-24
HUE026613T2 (hu) 2016-06-28
CN101035531B (zh) 2013-01-02
JP2008512474A (ja) 2008-04-24
CN101035531A (zh) 2007-09-12
IL181849A (en) 2013-11-28
EA012606B1 (ru) 2009-10-30
EP1789040B1 (en) 2015-12-23
US7645783B2 (en) 2010-01-12
IL203061A (en) 2013-04-30
ZA200702066B (en) 2008-08-27
US20060089396A1 (en) 2006-04-27
US7550493B2 (en) 2009-06-23
US20080097106A1 (en) 2008-04-24
IL181849A0 (en) 2007-07-04
HRP20151439T1 (hr) 2016-02-12
AU2005285157A1 (en) 2006-03-23
JP4998852B2 (ja) 2012-08-15
DK1789040T3 (en) 2016-02-01
RS54453B1 (en) 2016-06-30
HK1106139A1 (zh) 2008-03-07
ES2559672T3 (es) 2016-02-15
AU2005285157B2 (en) 2009-07-16
CA2580347A1 (en) 2006-03-23
CY1118689T1 (el) 2017-07-12
PL1789040T3 (pl) 2016-04-29
US7285567B2 (en) 2007-10-23
UA90864C2 (en) 2010-06-10
EA200700432A1 (ru) 2007-10-26
BRPI0515089B1 (pt) 2019-07-16
AP2007003950A0 (en) 2007-04-30
WO2006031566A3 (en) 2006-06-08
EP1789040A2 (en) 2007-05-30
PT1789040E (pt) 2016-02-19
ME02370B (me) 2016-06-20
MX2007002969A (es) 2008-02-15
EP1789040A4 (en) 2009-09-02

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