ZA200708775B - Substituted amide derivatives as protein kinase inhibitors - Google Patents
Substituted amide derivatives as protein kinase inhibitors Download PDFInfo
- Publication number
- ZA200708775B ZA200708775B ZA200708775A ZA200708775A ZA200708775B ZA 200708775 B ZA200708775 B ZA 200708775B ZA 200708775 A ZA200708775 A ZA 200708775A ZA 200708775 A ZA200708775 A ZA 200708775A ZA 200708775 B ZA200708775 B ZA 200708775B
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- Prior art keywords
- optionally substituted
- phenyl
- alkyl
- methyl
- carboxamide
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- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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- C07D—HETEROCYCLIC COMPOUNDS
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- C—CHEMISTRY; METALLURGY
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- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
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- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Pulmonology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
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- Dermatology (AREA)
- Reproductive Health (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
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- Molecular Biology (AREA)
- Transplantation (AREA)
- Pregnancy & Childbirth (AREA)
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Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67580505P | 2005-04-27 | 2005-04-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200708775B true ZA200708775B (en) | 2008-06-25 |
Family
ID=36617399
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200708775A ZA200708775B (en) | 2005-04-27 | 2007-10-15 | Substituted amide derivatives as protein kinase inhibitors |
Country Status (34)
Country | Link |
---|---|
US (3) | US7858623B2 (el) |
EP (1) | EP1881976B1 (el) |
JP (1) | JP5463033B2 (el) |
KR (1) | KR20080004617A (el) |
CN (1) | CN101248059A (el) |
AR (1) | AR054262A1 (el) |
AU (1) | AU2006239216B2 (el) |
BR (1) | BRPI0608097A2 (el) |
CA (1) | CA2605680C (el) |
CR (1) | CR9475A (el) |
CY (1) | CY1113324T1 (el) |
DK (1) | DK1881976T3 (el) |
EA (1) | EA013231B1 (el) |
ES (1) | ES2396219T3 (el) |
GT (1) | GT200600181A (el) |
HK (1) | HK1116161A1 (el) |
HN (1) | HN2006016313A (el) |
HR (1) | HRP20121069T1 (el) |
IL (1) | IL186526A (el) |
JO (1) | JO2787B1 (el) |
MX (1) | MX2007013216A (el) |
MY (1) | MY177111A (el) |
NO (1) | NO20076093L (el) |
NZ (1) | NZ562595A (el) |
PE (1) | PE20061436A1 (el) |
PL (1) | PL1881976T3 (el) |
PT (1) | PT1881976E (el) |
RS (1) | RS52596B (el) |
SI (1) | SI1881976T1 (el) |
TW (1) | TWI378094B (el) |
UA (1) | UA93375C2 (el) |
UY (1) | UY29503A1 (el) |
WO (1) | WO2006116713A1 (el) |
ZA (1) | ZA200708775B (el) |
Families Citing this family (165)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE0302486D0 (sv) | 2003-09-18 | 2003-09-18 | Astrazeneca Ab | Novel compounds |
WO2005070891A2 (en) * | 2004-01-23 | 2005-08-04 | Amgen Inc | Compounds and methods of use |
WO2006010264A1 (en) | 2004-07-30 | 2006-02-02 | Methylgene, Inc. | Inhibitors of vegf receptor and hgf receptor signaling |
ES2524922T3 (es) | 2005-05-10 | 2014-12-15 | Intermune, Inc. | Derivados de piridona para modular el sistema de proteína cinasa activada por estrés |
MX2007014617A (es) | 2005-05-20 | 2008-02-11 | Methylgene Inc | Inhibidores de senalizacion de receptor de factor de crecimiento endotelial bascular y receptor de factor de crecimiento de hepatocitos. |
JP5148499B2 (ja) * | 2005-05-20 | 2013-02-20 | メチルジーン インコーポレイテッド | Vegf受容体およびhgf受容体シグナル伝達の阻害剤 |
US7880004B2 (en) | 2005-09-15 | 2011-02-01 | Bristol-Myers Squibb Company | Met kinase inhibitors |
US7700567B2 (en) | 2005-09-29 | 2010-04-20 | Supergen, Inc. | Oligonucleotide analogues incorporating 5-aza-cytosine therein |
AR055206A1 (es) * | 2005-10-06 | 2007-08-08 | Schering Corp | Pirazolo[1, 5 - a]pirimidinas como inhibidoras de proteina quinasa, composiciones farmaceuticas y combinaciones con agentes citostaticos que las comprenden y su uso en la fabricacion de un medicamento para el tratamiento del cancer. |
TW200806675A (en) | 2006-01-30 | 2008-02-01 | Array Biopharma Inc | Heterobicyclic thiophene compounds and methods of use |
KR20080110783A (ko) | 2006-03-07 | 2008-12-19 | 어레이 바이오파마 인크. | 헤테로바이시클릭 피라졸 화합물 및 사용 방법 |
EP2371865B1 (en) | 2006-04-07 | 2017-07-12 | Aerpio Therapeutics, Inc. | Antibodies that bind human protein tyrosine phosphatase beta (HPTP-ß) and uses thereof |
TW200808763A (en) | 2006-05-08 | 2008-02-16 | Astrazeneca Ab | Novel compounds I |
TW200808771A (en) | 2006-05-08 | 2008-02-16 | Astrazeneca Ab | Novel compounds II |
EP2023926B1 (en) * | 2006-05-19 | 2011-10-12 | Bayer Pharma Aktiengesellschaft | Pyridonecarboxamide derivatives useful in treating hyper-proliferative and angiogenesis disorders |
US20080004273A1 (en) * | 2006-05-30 | 2008-01-03 | Stephane Raeppel | Inhibitors of protein tyrosine kinase activity |
EP2032538A2 (en) * | 2006-06-08 | 2009-03-11 | Array Biopharma, Inc. | Quinoline compounds and methods of use |
US7622593B2 (en) | 2006-06-27 | 2009-11-24 | The Procter & Gamble Company | Human protein tyrosine phosphatase inhibitors and methods of use |
EP2038272B8 (en) * | 2006-06-30 | 2013-10-23 | Sunesis Pharmaceuticals, Inc. | Pyridinonyl pdk1 inhibitors |
AU2007317296B2 (en) | 2006-11-08 | 2012-07-05 | Bristol-Myers Squibb Company | Pyridinone compounds |
AU2007338795B2 (en) * | 2006-12-20 | 2012-07-19 | Amgen Inc. | Substituted heterocycles and methods of use |
CA2672438A1 (en) | 2006-12-20 | 2008-07-03 | Amgen Inc. | Substituted heterocycles and methods of use |
JP5528812B2 (ja) | 2006-12-20 | 2014-06-25 | アムジエン・インコーポレーテツド | 複素環式化合物ならびに炎症、血管形成および癌の治療におけるこれらの使用 |
US7737149B2 (en) | 2006-12-21 | 2010-06-15 | Astrazeneca Ab | N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-2H-pyrazol-3-yl]-4-(3,5-dimethylpiperazin-1-yl)benzamide and salts thereof |
JP2010519204A (ja) * | 2007-02-16 | 2010-06-03 | アムジエン・インコーポレーテツド | 窒素含有複素環ケトン類およびそれらのc−Met阻害薬としての使用 |
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