SE9301830D0 - New compounds - Google Patents
New compoundsInfo
- Publication number
- SE9301830D0 SE9301830D0 SE19939301830A SE9301830A SE9301830D0 SE 9301830 D0 SE9301830 D0 SE 9301830D0 SE 19939301830 A SE19939301830 A SE 19939301830A SE 9301830 A SE9301830 A SE 9301830A SE 9301830 D0 SE9301830 D0 SE 9301830D0
- Authority
- SE
- Sweden
- Prior art keywords
- new compounds
- improved
- omeprazole
- enantiomer
- manufacture
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- SUBDBMMJDZJVOS-UHFFFAOYSA-N 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole Chemical compound N=1C2=CC(OC)=CC=C2NC=1S(=O)CC1=NC=C(C)C(OC)=C1C SUBDBMMJDZJVOS-UHFFFAOYSA-N 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 210000004211 gastric acid Anatomy 0.000 abstract 1
- 159000000011 group IA salts Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000002503 metabolic effect Effects 0.000 abstract 1
- 229960000381 omeprazole Drugs 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Preventing Corrosion Or Incrustation Of Metals (AREA)
Priority Applications (73)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE19939301830A SE9301830D0 (sv) | 1993-05-28 | 1993-05-28 | New compounds |
IS4161A IS1854B (is) | 1993-05-28 | 1994-05-06 | Aðferð til að útbúa ljósfræðilega hrein Na+, Mg2+, Li+, K+ eða Ca2+ sölt (-)-5-metoxý-2-[[(4-metoxý-3,5-dímetýl-2-pýridínýl)metýl]súlfinýl]-1H-bensimídasóls og milliefnasamband. |
TW083104255A TW389761B (en) | 1993-05-28 | 1994-05-11 | Omeprazole and its alkaline salts with high optically purity, their pharmaceutical compositions, process for preparation including their intermediates and application in pharmaceuticals |
HR940307A HRP940307B1 (en) | 1993-05-28 | 1994-05-17 | New compounds |
LTIP1941A LT3287B (en) | 1993-05-28 | 1994-05-18 | Optical pure compounds, a process for their preparation and their use |
IL10968494A IL109684A (en) | 1993-05-28 | 1994-05-19 | Optically pure crystalline salts of the (-)-enantiomer of omeprazole, process for their preparation and pharmaceutical compositions containing them |
ZA943557A ZA943557B (en) | 1993-05-28 | 1994-05-23 | Highly optical pure benzimidazoles and salts thereof |
DZ940055A DZ1785A1 (fr) | 1993-05-28 | 1994-05-25 | Nouveaux composés. |
MA23521A MA23210A1 (fr) | 1993-05-28 | 1994-05-26 | Nouveaux composes |
EP94917244A EP0652872B1 (en) | 1993-05-28 | 1994-05-27 | Optically pure magnesium -salt of pyridinylmethyl sulfinyl-1h-benzimidazole compound |
DE69426254T DE69426254T2 (de) | 1993-05-28 | 1994-05-27 | Optisch reines magnesium-salz eines pyridinylmethylsulfinyl-1h-benzimidazole-derivats |
AT94917244T ATE197452T1 (de) | 1993-05-28 | 1994-05-27 | Optisch reines magnesium-salz eines pyridinylmethylsulfinyl-1h-benzimidazole-deriva s |
UA95018075A UA60289C2 (uk) | 1993-05-28 | 1994-05-27 | Оптично чисті солі (-)-5-метокси-2-[[(4-метокси-3,5-диметил-2-піридиніл)метил]сульфініл]-1h-бензімідазолу, спосіб їх одержання, проміжні сполуки та фармацевтична композиція |
KR1019950700365A KR100337274B1 (ko) | 1993-05-28 | 1994-05-27 | 피리딘메틸술피닐-1h-벤즈이미다졸화합물의광학적으로순수한염 |
US08/256,174 US5693818A (en) | 1993-05-28 | 1994-05-27 | Process for preparing pure salts of pyridinylmethyl-sulfinyl-1H-benzimidazole |
SI9420085A SI22752B (sl) | 1993-05-28 | 1994-05-27 | Optično čiste soli piridinilmetil sulfinil-1H-benzimidazolovih spojin |
PCT/SE1994/000509 WO1994027988A1 (en) | 1993-05-28 | 1994-05-27 | Optically pure salts of pyridinylmethyl sulfinyl-ih-benzimidazole compounds |
JP50055395A JP3549111B2 (ja) | 1993-05-28 | 1994-05-27 | 新規な化合物 |
NZ266915A NZ266915A (en) | 1993-05-28 | 1994-05-27 | Optically pure salts of (+)- and (-)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl] -sulphinyl]-1h-benzimidazole; pharmaceutical compositions (omeprazole) |
ES94917244T ES2099047T3 (es) | 1993-05-28 | 1994-05-27 | Sal de magnesio opticamente pura de un compuesto de piridinilmetilsulfinil-1h-bencimidazol. |
CA002139653A CA2139653C (en) | 1993-05-28 | 1994-05-27 | Optically pure salts of pyridinylmethyl sulfinyl-ih- benzimidazole compounds |
RU95105587A RU2137766C1 (ru) | 1993-05-28 | 1994-05-27 | Оптически чистые na+, mg2+, li+, k+ или са2+ соли (-)-5-метокси-2[[(4-метокси-3,5-диметил-2-пиридинил)метил] сульфинил]-1h-бензимидазола, способ их получения, фармкомпозиция на их основе и промежуточное соединение |
EP00108480.5A EP1020461B2 (en) | 1993-05-28 | 1994-05-27 | Magnesium salt of the (-)-enantiomer of omeprazole and its use |
YU31494A YU49065B (sh) | 1993-05-28 | 1994-05-27 | Omeprazol enantiomeri, postupak za njihovo dobijanje, farmaceutski proizvodi i njihova upotreba u medicini |
PL94307261A PL178994B1 (pl) | 1993-05-28 | 1994-05-27 | Optycznie czyste sole zwiazków pirydynylometylosulfinylo-1H-benzimidazolu i srodek farmaceutyczny je zawierajacy PL PL PL PL PL PL PL |
MYPI94001349A MY121192A (en) | 1993-05-28 | 1994-05-27 | New compounds. |
DK94917244T DK0652872T3 (da) | 1993-05-28 | 1994-05-27 | Optisk rent magnesiumsalt af pyridinylmethylsulfinyl-1H-benzimidazolforbindelse |
DE69435221T DE69435221D1 (de) | 1993-05-28 | 1994-05-27 | Magnesiumsalz des (-)-Enantiomers von Omeprazol und dessen Verwendung |
TNTNSN94058A TNSN94058A1 (fr) | 1993-05-28 | 1994-05-27 | Nouveaux composes |
PT94917244T PT652872E (pt) | 1993-05-28 | 1994-05-27 | Sal de magnesio do composto piridinil metil sulfinil-1h-benzimidazole opticamente puro |
AU69024/94A AU676337C (en) | 1993-05-28 | 1994-05-27 | Optically pure salts of pyridinylmethyl sulfinyl-IH- benzimidazole compounds |
CA002337581A CA2337581A1 (en) | 1993-05-28 | 1994-05-27 | Optically pure salts of pyridinylmethyl sulfinyl-1h-benzimidazole compounds and intermediates in the preparation therefor |
ES00108479T ES2326404T3 (es) | 1993-05-28 | 1994-05-27 | Sal sodica del enantiomero (-) de omeprazol. |
DK00108479T DK1020460T3 (da) | 1993-05-28 | 1994-05-27 | Natriumsalt af (-)enantiomeren af omeprazol |
DE69435220T DE69435220D1 (de) | 1993-05-28 | 1994-05-27 | Das Natrium Salz des (-)-Enantiomer von Omeprazole |
CZ1995202A CZ287876B6 (cs) | 1993-05-28 | 1994-05-27 | Opticky čistý pyridylmethylsulfinyl-1H-benzimidazolový derivát, způsob jeho výroby, farmaceutický prostředek s jeho obsahem a meziprodukt pro jeho výrobu |
DE0652872T DE652872T1 (de) | 1993-05-28 | 1994-05-27 | Optisch reine salze von pyridinylmethylsulfinyl-1h-benzimidazole-derivaten. |
SK101-95A SK282524B6 (sk) | 1993-05-28 | 1994-05-27 | Opticky čisté soli (-)-enantioméru pyridylmetylsulfinyl-1H- benzimidazolových zlúčenín, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom, ich použitie a medziprodukty na ich prípravu |
SG1996008770A SG49283A1 (en) | 1993-05-28 | 1994-05-27 | New compounds |
HU9500247A HU226824B1 (en) | 1993-05-28 | 1994-05-27 | Optically active salts of pyridinyl-methyl-sulfinyl-1h-benzimidazol derivatives, pharmaceutical compositions containing them and process for producing them |
EP00108479A EP1020460B1 (en) | 1993-05-28 | 1994-05-27 | The sodium salt of the (-)-enantiomer of omeprazole |
PT00108479T PT1020460E (pt) | 1993-05-28 | 1994-05-27 | Sal de sódio do enantiómero (-) de omeprazole |
DK00108480.5T DK1020461T4 (en) | 1993-05-28 | 1994-05-27 | The magnesium salt of the (-) enantiomer of omeprazole and the use of this |
CN94190335A CN1055469C (zh) | 1993-05-28 | 1994-05-27 | 旋光纯的吡啶甲基亚磺酰基-1h-苯并咪唑类化合物的盐、及其制法和应用 |
PT00108480T PT1020461E (pt) | 1993-05-28 | 1994-05-27 | Sal de magnésio do enantiómero (-) de omeprazole |
ES00108480.5T ES2326405T5 (es) | 1993-05-28 | 1994-05-27 | Sal de magnesio del enantiómero(-) del omeprazol y su uso |
SI9420002A SI9420002B (sl) | 1993-05-28 | 1994-05-27 | Optično čiste soli piridinilmetil sulfinil-1H-benzimidazolovih spojin |
SA05260103A SA05260103B1 (ar) | 1993-05-28 | 1994-06-04 | ملح الصوديوم للمتشاكل -(-) للأومبرازول |
SA94140756A SA94140756B1 (ar) | 1993-05-28 | 1994-06-04 | ملح magnesium نقي ضوئياً لمركب pyridinylmethyl sulfinyl- 1H- benzimidazole |
EE9400363A EE03157B1 (et) | 1993-05-28 | 1994-11-17 | Omeprasooli enantiomeerid, nende valmistamise protsess ja neid sisaldavad ravimpreparaadid |
LVP-94-266A LV11034B (en) | 1993-05-28 | 1994-12-30 | Optically pure salts of pyridinilmethyl sulfinyl-1h-benzimidazole compounds |
US08/376,512 US5714504A (en) | 1993-05-28 | 1995-01-23 | Compositions |
NO950263A NO307378B1 (no) | 1993-05-28 | 1995-01-24 | Optisk rene salter av pyridinylmetylsulfinyl-1H- benzimidazolforbindelser, fremgangsmåte for deres fremstilling, farmasøytisk preparat inneholdende slike forbindelser og deres anvendelse samt mellomprodukter |
FI950377A FI117755B (fi) | 1993-05-28 | 1995-01-27 | Menetelmä pyridinyylimetyylisulfinyyli-1H-bentsimidatsoliyhdisteen terapeuttisesti aktiivisen, optisesti puhtaan natrium- tai magnesiumsuolan valmistamiseksi |
US08/833,962 US5877192A (en) | 1993-05-28 | 1997-04-11 | Method for the treatment of gastric acid-related diseases and production of medication using (-) enantiomer of omeprazole |
GR970300012T GR970300012T1 (en) | 1993-05-28 | 1997-05-30 | Optically pure salts of pyridinylmethyl sulfinyl-1h-benzimidazole compounds. |
HK98109228A HK1008330A1 (en) | 1993-05-28 | 1998-07-17 | Optically pure magnesium-salt of pyridinylmethyl sulfinyl-1h-benzimidazole compound |
CN99118539A CN1107503C (zh) | 1993-05-28 | 1999-09-03 | 一种旋光纯化合物的药用 |
US09/419,456 US6143771A (en) | 1993-05-28 | 1999-10-15 | Compounds |
US09/690,044 US6875872B1 (en) | 1993-05-28 | 2000-10-16 | Compounds |
HK00107518.8A HK1028044A1 (en) | 1993-05-28 | 2000-11-23 | Magnesium salt of the (-)-enantiomer of omeprazole and its use |
HK00107520.4A HK1028045A1 (en) | 1993-05-28 | 2000-11-23 | The sodium salt of the (-)-enantiomer of omeprazole |
GR20010400191T GR3035365T3 (en) | 1993-05-28 | 2001-02-05 | Optically pure salts of pyridinylmethyl sulfinyl-1h-benzimidazole compounds. |
CY0100010A CY2224B1 (en) | 1993-05-28 | 2001-05-22 | Optically pure salts of pyridinylmethyl sulfinyl-1H-benzimidazole compounds |
JP2003317637A JP3959056B2 (ja) | 1993-05-28 | 2003-09-10 | 新規な化合物 |
JP2003317639A JP4039999B2 (ja) | 1993-05-28 | 2003-09-10 | 新規な化合物の製造方法 |
US11/002,982 US20060004057A1 (en) | 1993-05-28 | 2004-12-01 | New compounds |
FI20070002A FI20070002L (fi) | 1993-05-28 | 2007-01-02 | Pyridinyylimetyylisulfinyyli-1H-bentsimidatsoliyhdisteiden optisesti puhtaat suolat |
US11/679,264 US20080312449A1 (en) | 1993-05-28 | 2007-02-27 | New Compounds |
CL2009000805A CL2009000805A1 (es) | 1993-05-28 | 2009-04-02 | Composicion farmaceutica que comprende a una sal sodica del enantiomero (-) de 5-metoxi-2[[(4-metoxi-3,5-dimetil-2-piridinil)metil]sulfinil]-1h-bencimidazol ((-)-omeprazol); y su uso en la inhibicion de la secrecion de acido gastrico y para tratar enfermedades inflamatorias gastrointestinales. (divisional solicitud 3570-00). |
US12/551,828 US20100222591A1 (en) | 1993-05-28 | 2009-09-01 | New Compounds |
NO2011009C NO2011009I1 (no) | 1993-05-28 | 2011-06-07 | Naproksen- og esomeprazoltabletter med modifisert frisetting |
LU91870C LU91870I2 (fr) | 1993-05-28 | 2011-09-19 | Une combinaison de produit comprenant du naproxèneet un sel de magnésium d'esomeprazole |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE19939301830A SE9301830D0 (sv) | 1993-05-28 | 1993-05-28 | New compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
SE9301830D0 true SE9301830D0 (sv) | 1993-05-28 |
Family
ID=20390088
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE19939301830A SE9301830D0 (sv) | 1993-05-28 | 1993-05-28 | New compounds |
Country Status (43)
Families Citing this family (210)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5877192A (en) * | 1993-05-28 | 1999-03-02 | Astra Aktiebolag | Method for the treatment of gastric acid-related diseases and production of medication using (-) enantiomer of omeprazole |
SE9301830D0 (sv) * | 1993-05-28 | 1993-05-28 | Ab Astra | New compounds |
US6875872B1 (en) * | 1993-05-28 | 2005-04-05 | Astrazeneca | Compounds |
DK1078628T3 (da) * | 1994-07-08 | 2009-02-23 | Astrazeneca Ab | Tabletteret flerenhedsdoseringsform |
SE504459C2 (sv) * | 1994-07-15 | 1997-02-17 | Astra Ab | Förfarande för framställning av substituerade sulfoxider |
SE9500422D0 (sv) * | 1995-02-06 | 1995-02-06 | Astra Ab | New oral pharmaceutical dosage forms |
SE9500478D0 (sv) * | 1995-02-09 | 1995-02-09 | Astra Ab | New pharmaceutical formulation and process |
HRP960232A2 (en) * | 1995-07-03 | 1998-02-28 | Astra Ab | A process for the optical purification of compounds |
US6699885B2 (en) * | 1996-01-04 | 2004-03-02 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and methods of using same |
US6489346B1 (en) * | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US6645988B2 (en) | 1996-01-04 | 2003-11-11 | Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
SE9600070D0 (sv) | 1996-01-08 | 1996-01-08 | Astra Ab | New oral pharmaceutical dosage forms |
SE508669C2 (sv) * | 1996-04-26 | 1998-10-26 | Astra Ab | Nytt förfarande |
SE510666C2 (sv) * | 1996-12-20 | 1999-06-14 | Astra Ab | Nya Kristallmodifikationer |
SE9702000D0 (sv) * | 1997-05-28 | 1997-05-28 | Astra Ab | New pharmaceutical formulation |
SE510650C2 (sv) | 1997-05-30 | 1999-06-14 | Astra Ab | Ny förening |
US6747155B2 (en) | 1997-05-30 | 2004-06-08 | Astrazeneca Ab | Process |
SE510643C2 (sv) * | 1997-06-27 | 1999-06-14 | Astra Ab | Termodynamiskt stabil omeprazol natrium form B |
US6174548B1 (en) | 1998-08-28 | 2001-01-16 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
US6096340A (en) * | 1997-11-14 | 2000-08-01 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
ES2216351T3 (es) * | 1997-12-08 | 2004-10-16 | Altana Pharma Ag | Nueva forma de supositorio que comprende un compuesto activo labil o acidos. |
SE9704870D0 (sv) * | 1997-12-22 | 1997-12-22 | Astra Ab | New pharmaceutical formulation I |
SE9704869D0 (sv) * | 1997-12-22 | 1997-12-22 | Astra Ab | New pharmaceutical formulaton II |
ATE526022T1 (de) * | 1998-04-20 | 2011-10-15 | Eisai R&D Man Co Ltd | Stabilisierte zusammenstellungen die benzimidazole enthalten |
ATE231857T1 (de) | 1998-08-10 | 2003-02-15 | Winston Pharmateuticals Llc | Prodrugs für proton-pump-inhibitoren |
US6733778B1 (en) | 1999-08-27 | 2004-05-11 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
SE9803772D0 (sv) | 1998-11-05 | 1998-11-05 | Astra Ab | Pharmaceutical formulation |
JP4610086B2 (ja) | 1998-11-18 | 2011-01-12 | アストラゼネカ・アクチエボラーグ | 改善された化学的方法および医薬処方物 |
SE9900274D0 (sv) * | 1999-01-28 | 1999-01-28 | Astra Ab | New compound |
US6852739B1 (en) * | 1999-02-26 | 2005-02-08 | Nitromed Inc. | Methods using proton pump inhibitors and nitric oxide donors |
TWI243672B (en) | 1999-06-01 | 2005-11-21 | Astrazeneca Ab | New use of compounds as antibacterial agents |
WO2000076556A2 (en) * | 1999-06-11 | 2000-12-21 | Neorx Corporation | High dose radionuclide complexes for bone marrow suppression |
US7094885B2 (en) * | 1999-07-11 | 2006-08-22 | Neorx Corporation | Skeletal-targeted radiation to treat bone-associated pathologies |
US6780880B1 (en) | 1999-08-26 | 2004-08-24 | Robert R. Whittle | FT-Raman spectroscopic measurement |
US6268385B1 (en) | 1999-08-26 | 2001-07-31 | Robert R. Whittle | Dry blend pharmaceutical formulations |
US6262085B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
US6326384B1 (en) | 1999-08-26 | 2001-12-04 | Robert R. Whittle | Dry blend pharmaceutical unit dosage form |
EP1595879A3 (en) * | 1999-08-26 | 2010-01-27 | aaiPharma Inc. | Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
US6262086B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Pharmaceutical unit dosage form |
US6316020B1 (en) * | 1999-08-26 | 2001-11-13 | Robert R. Whittle | Pharmaceutical formulations |
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