IL133420A - תכשיר רוקחות בצורת טבליה המכיל שילוב פיפרידינואלקאנול אנטיהיסטמיני ומפחית גודש סימפטומימטי - Google Patents

תכשיר רוקחות בצורת טבליה המכיל שילוב פיפרידינואלקאנול אנטיהיסטמיני ומפחית גודש סימפטומימטי

Info

Publication number: IL133420A
Authority: IL; Israel
Prior art keywords: formulation; amount; weight; pharmaceutical composition; carrier base
Prior art date: 1997-08-26

Application number

IL13342098A

Other languages

English (en)

Other versions

IL133420A0 (en

Original Assignee

Aventis Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-08-26

Filing date

1998-07-21

Publication date

2004-07-25

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25443270&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL133420(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1998-07-21 Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc

2001-04-30 Publication of IL133420A0 publication Critical patent/IL133420A0/xx

2004-07-25 Publication of IL133420A publication Critical patent/IL133420A/he

Links

239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 38
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239000004166 Lanolin Substances 0.000 description 1
WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 description 1
FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
241001465754 Metazoa Species 0.000 description 1
241000699670 Mus sp. Species 0.000 description 1
OPKOKAMJFNKNAS-UHFFFAOYSA-N N-methylethanolamine Chemical compound CNCCO OPKOKAMJFNKNAS-UHFFFAOYSA-N 0.000 description 1
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
IWYDHOAUDWTVEP-UHFFFAOYSA-N R-2-phenyl-2-hydroxyacetic acid Natural products OC(=O)C(O)C1=CC=CC=C1 IWYDHOAUDWTVEP-UHFFFAOYSA-N 0.000 description 1
241000700159 Rattus Species 0.000 description 1
206010039085 Rhinitis allergic Diseases 0.000 description 1
208000036284 Rhinitis seasonal Diseases 0.000 description 1
206010040744 Sinus headache Diseases 0.000 description 1
FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
239000008186 active pharmaceutical agent Substances 0.000 description 1
229910052783 alkali metal Inorganic materials 0.000 description 1
150000001340 alkali metals Chemical class 0.000 description 1
229910052784 alkaline earth metal Inorganic materials 0.000 description 1
150000001342 alkaline earth metals Chemical class 0.000 description 1
125000003282 alkyl amino group Chemical group 0.000 description 1
201000010105 allergic rhinitis Diseases 0.000 description 1
229910052782 aluminium Inorganic materials 0.000 description 1
XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
230000003266 anti-allergic effect Effects 0.000 description 1
125000004429 atom Chemical group 0.000 description 1
239000011324 bead Substances 0.000 description 1
WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid group Chemical group C(C1=CC=CC=C1)(=O)O WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 1
238000009835 boiling Methods 0.000 description 1
229910052794 bromium Inorganic materials 0.000 description 1
230000003182 bronchodilatating effect Effects 0.000 description 1
239000011575 calcium Substances 0.000 description 1
229910052791 calcium Inorganic materials 0.000 description 1
229910000019 calcium carbonate Inorganic materials 0.000 description 1
229960003563 calcium carbonate Drugs 0.000 description 1
229910052799 carbon Inorganic materials 0.000 description 1
150000005323 carbonate salts Chemical class 0.000 description 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
150000001735 carboxylic acids Chemical class 0.000 description 1
230000015556 catabolic process Effects 0.000 description 1
239000003093 cationic surfactant Substances 0.000 description 1
229960000541 cetyl alcohol Drugs 0.000 description 1
238000002144 chemical decomposition reaction Methods 0.000 description 1
239000003153 chemical reaction reagent Substances 0.000 description 1
239000003795 chemical substances by application Substances 0.000 description 1
239000000460 chlorine Substances 0.000 description 1
229910052801 chlorine Inorganic materials 0.000 description 1
229940124301 concurrent medication Drugs 0.000 description 1
238000007796 conventional method Methods 0.000 description 1
239000000498 cooling water Substances 0.000 description 1
125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 description 1
125000001511 cyclopentyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 description 1
238000000354 decomposition reaction Methods 0.000 description 1
238000006731 degradation reaction Methods 0.000 description 1
150000004683 dihydrates Chemical class 0.000 description 1
238000006073 displacement reaction Methods 0.000 description 1
238000011978 dissolution method Methods 0.000 description 1
238000007922 dissolution test Methods 0.000 description 1
229940079593 drug Drugs 0.000 description 1
238000009506 drug dissolution testing Methods 0.000 description 1
229940088679 drug related substance Drugs 0.000 description 1
230000000694 effects Effects 0.000 description 1
230000008030 elimination Effects 0.000 description 1
238000003379 elimination reaction Methods 0.000 description 1
CCIVGXIOQKPBKL-UHFFFAOYSA-M ethanesulfonate Chemical compound CCS([O-])(=O)=O CCIVGXIOQKPBKL-UHFFFAOYSA-M 0.000 description 1
238000001914 filtration Methods 0.000 description 1
229910052731 fluorine Inorganic materials 0.000 description 1
239000011737 fluorine Substances 0.000 description 1
229920000159 gelatin Polymers 0.000 description 1
239000008273 gelatin Substances 0.000 description 1
235000019322 gelatine Nutrition 0.000 description 1
235000011852 gelatine desserts Nutrition 0.000 description 1
235000011187 glycerol Nutrition 0.000 description 1
150000004820 halides Chemical class 0.000 description 1
229910052736 halogen Inorganic materials 0.000 description 1
150000002367 halogens Chemical class 0.000 description 1
230000036541 health Effects 0.000 description 1
125000000623 heterocyclic group Chemical group 0.000 description 1
UWYVPFMHMJIBHE-OWOJBTEDSA-N hydroxymaleic acid group Chemical group O/C(/C(=O)O)=C/C(=O)O UWYVPFMHMJIBHE-OWOJBTEDSA-N 0.000 description 1
150000007529 inorganic bases Chemical class 0.000 description 1
229910052740 iodine Inorganic materials 0.000 description 1
239000008101 lactose Substances 0.000 description 1
229960001375 lactose Drugs 0.000 description 1
235000019388 lanolin Nutrition 0.000 description 1
229940039717 lanolin Drugs 0.000 description 1
229910052744 lithium Inorganic materials 0.000 description 1
239000011777 magnesium Substances 0.000 description 1
229910052749 magnesium Inorganic materials 0.000 description 1
229960002510 mandelic acid Drugs 0.000 description 1
238000005259 measurement Methods 0.000 description 1
238000002483 medication Methods 0.000 description 1
238000002844 melting Methods 0.000 description 1
230000008018 melting Effects 0.000 description 1
QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
229910052753 mercury Inorganic materials 0.000 description 1
229910052751 metal Inorganic materials 0.000 description 1
239000002184 metal Substances 0.000 description 1
150000002739 metals Chemical class 0.000 description 1
229940063559 methacrylic acid Drugs 0.000 description 1
239000002480 mineral oil Substances 0.000 description 1
235000010446 mineral oil Nutrition 0.000 description 1
238000012986 modification Methods 0.000 description 1
230000004048 modification Effects 0.000 description 1
125000002950 monocyclic group Chemical group 0.000 description 1
GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 description 1
125000001280 n-hexyl group Chemical group C(CCCCC)* 0.000 description 1
125000000740 n-pentyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
201000009240 nasopharyngitis Diseases 0.000 description 1
239000002736 nonionic surfactant Substances 0.000 description 1
239000006186 oral dosage form Substances 0.000 description 1
235000005985 organic acids Nutrition 0.000 description 1
150000007530 organic bases Chemical class 0.000 description 1
239000012188 paraffin wax Substances 0.000 description 1
229940124531 pharmaceutical excipient Drugs 0.000 description 1
230000000144 pharmacologic effect Effects 0.000 description 1
WLJVXDMOQOGPHL-UHFFFAOYSA-N phenylacetic acid Chemical compound OC(=O)CC1=CC=CC=C1 WLJVXDMOQOGPHL-UHFFFAOYSA-N 0.000 description 1
235000011007 phosphoric acid Nutrition 0.000 description 1
150000003016 phosphoric acids Chemical class 0.000 description 1
229910052700 potassium Inorganic materials 0.000 description 1
239000011591 potassium Substances 0.000 description 1
229940069328 povidone Drugs 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
150000003141 primary amines Chemical class 0.000 description 1
UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
230000009467 reduction Effects 0.000 description 1
230000004044 response Effects 0.000 description 1
230000002441 reversible effect Effects 0.000 description 1
150000003335 secondary amines Chemical class 0.000 description 1
239000002356 single layer Substances 0.000 description 1
201000009890 sinusitis Diseases 0.000 description 1
235000010413 sodium alginate Nutrition 0.000 description 1
239000000661 sodium alginate Substances 0.000 description 1
229940005550 sodium alginate Drugs 0.000 description 1
229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
235000017557 sodium bicarbonate Nutrition 0.000 description 1
239000001488 sodium phosphate Substances 0.000 description 1
229910000162 sodium phosphate Inorganic materials 0.000 description 1
239000007787 solid Substances 0.000 description 1
239000002904 solvent Substances 0.000 description 1
241000894007 species Species 0.000 description 1
239000007858 starting material Substances 0.000 description 1
238000003756 stirring Methods 0.000 description 1
125000001424 substituent group Chemical group 0.000 description 1
229940089453 sudafed Drugs 0.000 description 1
150000003460 sulfonic acids Chemical class 0.000 description 1
230000001975 sympathomimetic effect Effects 0.000 description 1
208000024891 symptom Diseases 0.000 description 1
239000011975 tartaric acid Substances 0.000 description 1
235000002906 tartaric acid Nutrition 0.000 description 1
150000003512 tertiary amines Chemical class 0.000 description 1
239000012085 test solution Substances 0.000 description 1
238000012360 testing method Methods 0.000 description 1
125000001544 thienyl group Chemical group 0.000 description 1
231100000331 toxic Toxicity 0.000 description 1
230000002588 toxic effect Effects 0.000 description 1
RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
239000002699 waste material Substances 0.000 description 1
229940045860 white wax Drugs 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Pulmonology (AREA)
Virology (AREA)
Molecular Biology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Otolaryngology (AREA)
Immunology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

IL13342098A 1997-08-26 1998-07-21 תכשיר רוקחות בצורת טבליה המכיל שילוב פיפרידינואלקאנול אנטיהיסטמיני ומפחית גודש סימפטומימטי IL133420A (he)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US92015897A	1997-08-26	1997-08-26
PCT/US1998/015237 WO1999009957A1 (en)	1997-08-26	1998-07-21	Pharmaceutical composition for combination of piperidinoalkanol-decongestant

Publications (2)

Publication Number	Publication Date
IL133420A0 IL133420A0 (en)	2001-04-30
IL133420A true IL133420A (he)	2004-07-25

Family

ID=25443270

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL13342098A IL133420A (he)	1997-08-26	1998-07-21	תכשיר רוקחות בצורת טבליה המכיל שילוב פיפרידינואלקאנול אנטיהיסטמיני ומפחית גודש סימפטומימטי

Country Status (31)

Country	Link
US (1)	US6039974A (he)
EP (1)	EP0998272B1 (he)
JP (1)	JP4344405B2 (he)
KR (1)	KR100514264B1 (he)
CN (1)	CN1159012C (he)
AR (1)	AR013947A1 (he)
AT (1)	ATE238773T1 (he)
AU (1)	AU725811B2 (he)
BR (1)	BR9812001A (he)
CZ (1)	CZ295461B6 (he)
DE (1)	DE69814086T2 (he)
DK (1)	DK0998272T3 (he)
EE (1)	EE04294B1 (he)
ES (1)	ES2192781T3 (he)
HK (1)	HK1025904A1 (he)
HU (1)	HU224921B1 (he)
ID (1)	ID22891A (he)
IL (1)	IL133420A (he)
NO (1)	NO318246B1 (he)
NZ (1)	NZ501248A (he)
OA (1)	OA11285A (he)
PL (1)	PL192079B1 (he)
PT (1)	PT998272E (he)
RU (1)	RU2207879C2 (he)
SI (1)	SI0998272T1 (he)
SK (1)	SK283803B6 (he)
TR (1)	TR200000517T2 (he)
TW (1)	TW570812B (he)
UA (1)	UA60335C2 (he)
WO (1)	WO1999009957A1 (he)
ZA (1)	ZA987552B (he)

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EP2046303A1 (en) *	2006-06-30	2009-04-15	Teva Pharmaceutical Industries Ltd.	Pharmaceutical compositions comprising a combination of piperidinoalkanol and decongestant
KR20090037930A (ko) *	2006-07-11	2009-04-16	뮤추얼 파마슈티컬 컴퍼니 아이엔씨.	조절 방출 제형
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US20100143471A1 (en) *	2007-03-21	2010-06-10	Lupin Limited	Novel reduced dose pharmaceutical compositions of fexofenadine and pseudoephedrine
US20090076080A1 (en) *	2007-09-19	2009-03-19	Protia, Llc	Deuterium-enriched fexofenadine
BRPI0908596A2 (pt) *	2008-03-21	2015-09-15	Mylan Pharmaceuticals Inc	formulação e composição farmacêutica de liberação prolongada
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BR112014021090B1 (pt)	2012-02-27	2023-01-24	Vertex Pharmaceuticals Incorporated	Composição farmacêutica e uso de n-[2,4-bis(1,1-dimetiletil)-5-hidróxifenil]-1,4-di-hidro-4-oxoquinolina3-carboxamida na preparação da mesma
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1998
- 1998-07-21 UA UA99126576A patent/UA60335C2/uk unknown
- 1998-07-21 RU RU99125326/14A patent/RU2207879C2/ru active
- 1998-07-21 EE EEP200000098A patent/EE04294B1/xx unknown
- 1998-07-21 ID IDW991512A patent/ID22891A/id unknown
- 1998-07-21 SI SI9830454T patent/SI0998272T1/xx unknown
- 1998-07-21 SK SK1777-99A patent/SK283803B6/sk not_active IP Right Cessation
- 1998-07-21 IL IL13342098A patent/IL133420A/he not_active IP Right Cessation
- 1998-07-21 EP EP98937010A patent/EP0998272B1/en not_active Expired - Lifetime
- 1998-07-21 AU AU85820/98A patent/AU725811B2/en not_active Expired
- 1998-07-21 DK DK98937010T patent/DK0998272T3/da active
- 1998-07-21 CZ CZ19994581A patent/CZ295461B6/cs not_active IP Right Cessation
- 1998-07-21 NZ NZ501248A patent/NZ501248A/en not_active IP Right Cessation
- 1998-07-21 HU HU0002183A patent/HU224921B1/hu unknown
- 1998-07-21 KR KR10-1999-7011550A patent/KR100514264B1/ko not_active IP Right Cessation
- 1998-07-21 WO PCT/US1998/015237 patent/WO1999009957A1/en active IP Right Grant
- 1998-07-21 BR BR9812001-8A patent/BR9812001A/pt not_active IP Right Cessation
- 1998-07-21 CN CNB988085275A patent/CN1159012C/zh not_active Expired - Lifetime
- 1998-07-21 TR TR2000/00517T patent/TR200000517T2/xx unknown
- 1998-07-21 ES ES98937010T patent/ES2192781T3/es not_active Expired - Lifetime
- 1998-07-21 DE DE69814086T patent/DE69814086T2/de not_active Expired - Lifetime
- 1998-07-21 PL PL337348A patent/PL192079B1/pl unknown
- 1998-07-21 PT PT98937010T patent/PT998272E/pt unknown
- 1998-07-21 JP JP51430099A patent/JP4344405B2/ja not_active Expired - Lifetime
- 1998-07-21 AT AT98937010T patent/ATE238773T1/de active
- 1998-07-31 US US09/127,478 patent/US6039974A/en not_active Expired - Lifetime
- 1998-08-20 ZA ZA987552A patent/ZA987552B/xx unknown
- 1998-08-21 TW TW087113848A patent/TW570812B/zh not_active IP Right Cessation
- 1998-08-25 AR ARP980104196A patent/AR013947A1/es not_active Application Discontinuation
2000
- 2000-02-04 OA OA1200000029A patent/OA11285A/en unknown
- 2000-02-25 NO NO20000932A patent/NO318246B1/no not_active IP Right Cessation
- 2000-08-15 HK HK00105074A patent/HK1025904A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
ID22891A (id)	1999-12-16
NZ501248A (en)	2001-06-29
WO1999009957A1 (en)	1999-03-04
PT998272E (pt)	2003-09-30
US6039974A (en)	2000-03-21
BR9812001A (pt)	2000-09-26
CZ458199A3 (cs)	2000-05-17
ATE238773T1 (de)	2003-05-15
KR20010013543A (ko)	2001-02-26
AR013947A1 (es)	2001-01-31
OA11285A (en)	2003-07-29
AU8582098A (en)	1999-03-16
PL337348A1 (en)	2000-08-14
KR100514264B1 (ko)	2005-09-15
DE69814086D1 (de)	2003-06-05
NO20000932D0 (no)	2000-02-25
DE69814086T2 (de)	2004-04-08
NO318246B1 (no)	2005-02-21
DK0998272T3 (da)	2003-08-25
PL192079B1 (pl)	2006-08-31
ZA987552B (en)	1999-02-26
TW570812B (en)	2004-01-11
CN1268050A (zh)	2000-09-27
HUP0002183A3 (en)	2000-12-28
SK177799A3 (en)	2000-07-11
HUP0002183A2 (hu)	2000-11-28
CZ295461B6 (cs)	2005-08-17
EE04294B1 (et)	2004-06-15
EP0998272A1 (en)	2000-05-10
UA60335C2 (uk)	2003-10-15
EE200000098A (et)	2000-12-15
JP4344405B2 (ja)	2009-10-14
ES2192781T3 (es)	2003-10-16
SI0998272T1 (en)	2003-12-31
SK283803B6 (sk)	2004-02-03
HU224921B1 (hu)	2006-04-28
IL133420A0 (en)	2001-04-30
HK1025904A1 (en)	2000-12-01
NO20000932L (no)	2000-04-18
RU2207879C2 (ru)	2003-07-10
JP2002511102A (ja)	2002-04-09
AU725811B2 (en)	2000-10-19
EP0998272B1 (en)	2003-05-02
TR200000517T2 (tr)	2000-08-21
CN1159012C (zh)	2004-07-28

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KR100523242B1 (ko)	2005-10-24	이부프로펜을 함유하는 정제 조성물
Center et al.	0	2) Patent Application Publication o Pub. No.: US 2021/0161863 A1

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2016-06-30	KB	Patent renewed
2019-02-28	EXP	Patent expired