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BR9811937A - Método de aumentar a biodisponibilidade de fexofenadina e de seus derivados - Google Patents

Método de aumentar a biodisponibilidade de fexofenadina e de seus derivados

Info

Publication number
BR9811937A
BR9811937A BR9811937-0A BR9811937A BR9811937A BR 9811937 A BR9811937 A BR 9811937A BR 9811937 A BR9811937 A BR 9811937A BR 9811937 A BR9811937 A BR 9811937A
Authority
BR
Brazil
Prior art keywords
bioavailability
increasing
fexofenadine
derivatives
patient
Prior art date
Application number
BR9811937-0A
Other languages
English (en)
Inventor
Kin-Kai Hwang
Dennis H Giesing
Gail H Hurst
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of BR9811937A publication Critical patent/BR9811937A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/745—Polymers of hydrocarbons
    • A61K31/75—Polymers of hydrocarbons of ethene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/77—Polymers containing oxygen of oxiranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)

Abstract

Patente de Invenção: <B>"MéTODO DE AUMENTAR A BIODISPONIBILIDADE DE FEXOFENADINA E DE SEUS DERIVADOS"<D>. A presente invenção refere-se a um método de aumentar a biodisponibilidade de uma anti-histamina de piperidinoalcanol, em um paciente, o qual compreende co-administrar, ao dito paciente, uma quantidade anti-histamínica eficaz do dito piperidinoalcanol e uma quantidade de inibição de p-glicoproteína eficaz de um inibidor de p-glicoproteína.
BR9811937-0A 1997-08-14 1998-07-21 Método de aumentar a biodisponibilidade de fexofenadina e de seus derivados BR9811937A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91156397A 1997-08-14 1997-08-14
PCT/US1998/015098 WO1999008690A1 (en) 1997-08-14 1998-07-21 Method of enhancing bioavailability of fexofenadine and its derivatives

Publications (1)

Publication Number Publication Date
BR9811937A true BR9811937A (pt) 2000-09-05

Family

ID=25430473

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9811937-0A BR9811937A (pt) 1997-08-14 1998-07-21 Método de aumentar a biodisponibilidade de fexofenadina e de seus derivados

Country Status (30)

Country Link
EP (1) EP1003528B1 (pt)
JP (1) JP4295913B2 (pt)
KR (1) KR100522985B1 (pt)
CN (1) CN1143680C (pt)
AR (1) AR018505A1 (pt)
AT (1) ATE224721T1 (pt)
AU (1) AU725965C (pt)
BR (1) BR9811937A (pt)
CA (1) CA2301267C (pt)
CZ (1) CZ293666B6 (pt)
DE (1) DE69808303T2 (pt)
DK (1) DK1003528T3 (pt)
EE (1) EE04263B1 (pt)
ES (1) ES2179523T3 (pt)
HK (1) HK1025901A1 (pt)
HU (1) HU226823B1 (pt)
ID (1) ID24463A (pt)
IL (1) IL134521A (pt)
NO (1) NO325148B1 (pt)
NZ (1) NZ502133A (pt)
OA (1) OA11287A (pt)
PL (1) PL191607B1 (pt)
PT (1) PT1003528E (pt)
RU (1) RU2197967C2 (pt)
SK (1) SK283868B6 (pt)
TR (1) TR200000419T2 (pt)
TW (1) TWI240633B (pt)
UA (1) UA64765C2 (pt)
WO (1) WO1999008690A1 (pt)
ZA (1) ZA987221B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0812195B1 (en) 1995-02-28 2002-10-30 Aventis Pharmaceuticals Inc. Pharmaceutical composition for piperidinoalkanol compounds
ID22891A (id) * 1997-08-26 1999-12-16 Hoechst Marion Roussel Inc Komposisi farmasi untuk kombinasi piperidinoalkanol-dekongestan
GB9822170D0 (en) * 1998-10-13 1998-12-02 Danbioyst Uk Ltd Novel formulations of fexofenadine
BR0306329A (pt) * 2002-05-29 2005-04-26 Aventis Pharmaceuticals Holdin Método de tratamento de asma
JP2008120684A (ja) * 2005-03-07 2008-05-29 Kumamoto Univ 抗アレルギー薬
KR101106374B1 (ko) 2009-06-05 2012-01-19 민병욱 고체연료에 의한 가연성 가스 발생 장치
KR101117014B1 (ko) * 2009-09-09 2012-06-14 민병욱 부패성 폐기물의 바이오매스 처리에 의한 폐자원 재활용 방법 및 장치
CN101843616B (zh) * 2010-06-04 2011-07-27 西安万隆制药有限责任公司 一种盐酸非索非那定与微晶纤维素组合物及其制备方法
RU2453315C2 (ru) * 2010-08-17 2012-06-20 Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") Фармацевтическая композиция для лечения аллергических заболеваний
CN103687592A (zh) 2011-05-20 2014-03-26 安万特药物公司 包含非索非那定的药物组合物
RU2504018C1 (ru) * 2012-05-28 2014-01-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Рязанский государственный медицинский университет имени академика И.П. Павлова" Министерства здравоохранения и социального развития Российской Федерации Способ моделирования состояния индукции функциональной активности гликопротеина-р финастеридом в эксперименте
RU2553362C1 (ru) * 2014-01-09 2015-06-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Рязанский государственный медицинский университет имени академика И.П. Павлова" Министерства здравоохранения Российской Федерации Способ моделирования состояния ингибирования функциональной активности гликопротеина-р линестренолом в эксперименте
CN104188998A (zh) * 2014-09-18 2014-12-10 中山大学 一种柚皮苷与盐酸非索非那丁药物组合物及其制剂

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5567592A (en) * 1994-02-02 1996-10-22 Regents Of The University Of California Screening method for the identification of bioenhancers through the inhibition of P-glycoprotein transport in the gut of a mammal
AU5893796A (en) * 1995-06-07 1996-12-30 Novo Nordisk A/S Modification of polypeptides
EP0831870A4 (en) * 1995-06-07 1998-09-16 Avmax Inc USE OF ESSENTIAL OILS TO INCREASE THE BIOAVAILABILITY OF ORAL PHARMACEUTICAL COMPOUNDS

Also Published As

Publication number Publication date
IL134521A0 (en) 2001-04-30
ES2179523T3 (es) 2003-01-16
DE69808303T2 (de) 2003-05-22
OA11287A (en) 2003-10-22
KR20010022845A (ko) 2001-03-26
ID24463A (id) 2000-07-20
EE04263B1 (et) 2004-04-15
TR200000419T2 (tr) 2000-09-21
JP4295913B2 (ja) 2009-07-15
PT1003528E (pt) 2003-02-28
CN1143680C (zh) 2004-03-31
IL134521A (en) 2005-07-25
WO1999008690A1 (en) 1999-02-25
HUP0003189A2 (en) 2001-03-28
UA64765C2 (uk) 2004-03-15
DK1003528T3 (da) 2003-02-03
PL338579A1 (en) 2000-11-06
CN1267221A (zh) 2000-09-20
NZ502133A (en) 2002-03-28
CA2301267C (en) 2004-07-13
ZA987221B (en) 1999-02-15
EP1003528B1 (en) 2002-09-25
EE200000069A (et) 2000-10-16
HK1025901A1 (en) 2000-12-01
CA2301267A1 (en) 1999-02-25
KR100522985B1 (ko) 2005-10-21
TWI240633B (en) 2005-10-01
DE69808303D1 (de) 2002-10-31
CZ293666B6 (cs) 2004-06-16
JP2001515041A (ja) 2001-09-18
NO325148B1 (no) 2008-02-11
CZ2000522A3 (cs) 2000-09-13
AU725965C (en) 2004-04-22
NO20000706D0 (no) 2000-02-11
HUP0003189A3 (en) 2001-04-28
EP1003528A1 (en) 2000-05-31
AU725965B2 (en) 2000-10-26
SK1842000A3 (en) 2000-08-14
PL191607B1 (pl) 2006-06-30
ATE224721T1 (de) 2002-10-15
NO20000706L (no) 2000-04-13
HU226823B1 (hu) 2009-11-30
AR018505A1 (es) 2001-11-28
SK283868B6 (sk) 2004-03-02
AU8505098A (en) 1999-03-08
RU2197967C2 (ru) 2003-02-10

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PRESENTE PEDIDO, UMA VEZ QUE O MESMO NAO ATENDE AOS ARTS. 8O, 13, 24 E 25 DA LPI.

B25D Requested change of name of applicant approved

Owner name: AVENTIS PHARMACEUTICALS INC. (US)

Free format text: ALTERADO DE: HOECHST MARION ROUSSEL, INC.

B25G Requested change of headquarter approved

Owner name: AVENTIS PHARMACEUTICALS INC. (US)

Free format text: SEDE ALTERADA CONFORME SOLICITADO NA PETICAO NO 020070033918/RJ DE 19/03/2007.

B12B Appeal against refusal [chapter 12.2 patent gazette]
B15G Petition not considered as such [chapter 15.7 patent gazette]

Free format text: DESCONHECIDAS AS ALT. DE NOME E SEDE REQUERIDAS ATRAVES DA PETICAO NO 020080090002/RJ DE 27/06/2008, POR AUSENCIA DE FUNDAMENTACAO LEGAL, UMA VEZ QUE O PEDIDO FOI ARQUIVADO DEFINITIVAMENTE NA RPI 2060 DE 29/06/2010.

B15G Petition not considered as such [chapter 15.7 patent gazette]

Free format text: DESCONHECIDA A PETICAO DE TRANSFERENCIA NO 020100076561/RJ DE 18/08/2010, POR AUSENCIA DE FUNDAMENTACAO LEGAL, EM VIRTUDE DO ARQUIVAMENTO DEFINITIVO DO PEDIDO PUBLICADO NA RPI 2060 DE 29/06/2010.

B25B Requested transfer of rights rejected

Owner name: AVENTIS PHARMACEUTICALS INC. (US)

B25B Requested transfer of rights rejected

Owner name: AVENTIS PHARMACEUTICALS INC. (US)

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08H Application fees: decision cancelled [chapter 8.8 patent gazette]