US2647121A
(en)
|
1951-02-02 |
1953-07-28 |
Ruth P Jacoby |
Diamine-bis-acetamides
|
US2819718A
(en)
|
1953-07-16 |
1958-01-14 |
Isidore H Goldman |
Drainage tube
|
US2717909A
(en)
|
1953-09-24 |
1955-09-13 |
Monsanto Chemicals |
Hydroxyethyl-keryl-alkylene-ammonium compounds
|
US2844629A
(en)
|
1956-04-25 |
1958-07-22 |
American Home Prod |
Fatty acid amides and derivatives thereof
|
US3096560A
(en)
|
1958-11-21 |
1963-07-09 |
William J Liebig |
Process for synthetic vascular implants
|
FR1378382A
(fr)
|
1962-12-01 |
1964-11-13 |
Sandoz Sa |
Amides de l'acide amino-propionique, utilisables en particulier pour le traitement des fibres textiles
|
GB1072118A
(en)
|
1962-12-01 |
1967-06-14 |
Sandoz Ag |
Amides of aminopropionic acid
|
JPS5141663B1
(ru)
|
1966-03-12 |
1976-11-11 |
|
|
JPS4822365B1
(ru)
|
1968-10-25 |
1973-07-05 |
|
|
NL143127B
(nl)
|
1969-02-04 |
1974-09-16 |
Rhone Poulenc Sa |
Versterkingsorgaan voor een defecte hartklep.
|
US3614954A
(en)
|
1970-02-09 |
1971-10-26 |
Medtronic Inc |
Electronic standby defibrillator
|
US3614955A
(en)
|
1970-02-09 |
1971-10-26 |
Medtronic Inc |
Standby defibrillator and method of operation
|
JPS5024216Y1
(ru)
|
1970-12-29 |
1975-07-21 |
|
|
JPS5024216B1
(ru)
|
1970-12-29 |
1975-08-14 |
|
|
US3945052A
(en)
|
1972-05-01 |
1976-03-23 |
Meadox Medicals, Inc. |
Synthetic vascular graft and method for manufacturing the same
|
US3805301A
(en)
|
1972-07-28 |
1974-04-23 |
Meadox Medicals Inc |
Tubular grafts having indicia thereon
|
JPS49127908A
(ru)
|
1973-04-20 |
1974-12-07 |
|
|
JPS5624664B2
(ru)
|
1973-06-28 |
1981-06-08 |
|
|
US4013507A
(en)
|
1973-09-18 |
1977-03-22 |
California Institute Of Technology |
Ionene polymers for selectively inhibiting the vitro growth of malignant cells
|
JPS5123537A
(ja)
|
1974-04-26 |
1976-02-25 |
Adeka Argus Chemical Co Ltd |
Kasozaisoseibutsu
|
GB1527592A
(en)
|
1974-08-05 |
1978-10-04 |
Ici Ltd |
Wound dressing
|
US3995623A
(en)
|
1974-12-23 |
1976-12-07 |
American Hospital Supply Corporation |
Multipurpose flow-directed catheter
|
JPS5813576B2
(ja)
|
1974-12-27 |
1983-03-14 |
アデカ ア−ガスカガク カブシキガイシヤ |
安定化された合成高分子組成物
|
DE2520814A1
(de)
|
1975-05-09 |
1976-11-18 |
Bayer Ag |
Lichtstabilisierung von polyurethanen
|
US4281669A
(en)
|
1975-05-09 |
1981-08-04 |
Macgregor David C |
Pacemaker electrode with porous system
|
JPS5210847A
(en)
|
1975-07-16 |
1977-01-27 |
Nippon Steel Corp |
Pinch roll
|
US4096860A
(en)
|
1975-10-08 |
1978-06-27 |
Mclaughlin William F |
Dual flow encatheter
|
CA1069652A
(en)
|
1976-01-09 |
1980-01-15 |
Alain F. Carpentier |
Supported bioprosthetic heart valve with compliant orifice ring
|
US4134402A
(en)
|
1976-02-11 |
1979-01-16 |
Mahurkar Sakharam D |
Double lumen hemodialysis catheter
|
US4072146A
(en)
|
1976-09-08 |
1978-02-07 |
Howes Randolph M |
Venous catheter device
|
US4335723A
(en)
|
1976-11-26 |
1982-06-22 |
The Kendall Company |
Catheter having inflatable retention means
|
US4099528A
(en)
|
1977-02-17 |
1978-07-11 |
Sorenson Research Co., Inc. |
Double lumen cannula
|
US4140126A
(en)
|
1977-02-18 |
1979-02-20 |
Choudhury M Hasan |
Method for performing aneurysm repair
|
US4265745A
(en)
|
1977-05-25 |
1981-05-05 |
Teijin Limited |
Permselective membrane
|
US4182833A
(en)
|
1977-12-07 |
1980-01-08 |
Celanese Polymer Specialties Company |
Cationic epoxide-amine reaction products
|
US4180068A
(en)
|
1978-04-13 |
1979-12-25 |
Motion Control, Incorporated |
Bi-directional flow catheter with retractable trocar/valve structure
|
EP0005035B1
(en)
|
1978-04-19 |
1981-09-23 |
Imperial Chemical Industries Plc |
A method of preparing a tubular product by electrostatic spinning
|
US4284459A
(en)
|
1978-07-03 |
1981-08-18 |
The Kendall Company |
Method for making a molded catheter
|
US4227533A
(en)
|
1978-11-03 |
1980-10-14 |
Bristol-Myers Company |
Flushable urinary catheter
|
US4375817A
(en)
|
1979-07-19 |
1983-03-08 |
Medtronic, Inc. |
Implantable cardioverter
|
US4458066A
(en)
|
1980-02-29 |
1984-07-03 |
University Patents, Inc. |
Process for preparing polynucleotides
|
US4500707A
(en)
|
1980-02-29 |
1985-02-19 |
University Patents, Inc. |
Nucleosides useful in the preparation of polynucleotides
|
US5132418A
(en)
|
1980-02-29 |
1992-07-21 |
University Patents, Inc. |
Process for preparing polynucleotides
|
DE3010841A1
(de)
|
1980-03-21 |
1981-10-08 |
Ulrich Dr.med. 6936 Haag Uthmann |
Katheder
|
US4308085A
(en)
|
1980-07-28 |
1981-12-29 |
Jenoptik Jena Gmbh |
Process for the preparation of high molecular thermoplastic epoxide-amine-polyadducts
|
US4973679A
(en)
|
1981-03-27 |
1990-11-27 |
University Patents, Inc. |
Process for oligonucleo tide synthesis using phosphormidite intermediates
|
US4415732A
(en)
|
1981-03-27 |
1983-11-15 |
University Patents, Inc. |
Phosphoramidite compounds and processes
|
US4668777A
(en)
|
1981-03-27 |
1987-05-26 |
University Patents, Inc. |
Phosphoramidite nucleoside compounds
|
US4339369A
(en)
|
1981-04-23 |
1982-07-13 |
Celanese Corporation |
Cationic epoxide-amine reaction products
|
US4401796A
(en)
|
1981-04-30 |
1983-08-30 |
City Of Hope Research Institute |
Solid-phase synthesis of polynucleotides
|
US4373071A
(en)
|
1981-04-30 |
1983-02-08 |
City Of Hope Research Institute |
Solid-phase synthesis of polynucleotides
|
US4406656A
(en)
|
1981-06-01 |
1983-09-27 |
Brack Gillium Hattler |
Venous catheter having collapsible multi-lumens
|
US4475972A
(en)
|
1981-10-01 |
1984-10-09 |
Ontario Research Foundation |
Implantable material
|
US4401472A
(en)
|
1982-02-26 |
1983-08-30 |
Martin Marietta Corporation |
Hydraulic cement mixes and processes for improving hydraulic cement mixes
|
US4568329A
(en)
|
1982-03-08 |
1986-02-04 |
Mahurkar Sakharam D |
Double lumen catheter
|
US4546499A
(en)
|
1982-12-13 |
1985-10-15 |
Possis Medical, Inc. |
Method of supplying blood to blood receiving vessels
|
US4530113A
(en)
|
1983-05-20 |
1985-07-23 |
Intervascular, Inc. |
Vascular grafts with cross-weave patterns
|
US4550447A
(en)
|
1983-08-03 |
1985-11-05 |
Shiley Incorporated |
Vascular graft prosthesis
|
US4647416A
(en)
|
1983-08-03 |
1987-03-03 |
Shiley Incorporated |
Method of preparing a vascular graft prosthesis
|
US5104399A
(en)
|
1986-12-10 |
1992-04-14 |
Endovascular Technologies, Inc. |
Artificial graft and implantation method
|
US4571241A
(en)
|
1983-12-16 |
1986-02-18 |
Christopher T Graham |
Urinary catheter with collapsible urethral tube
|
US4710169A
(en)
|
1983-12-16 |
1987-12-01 |
Christopher T Graham |
Urinary catheter with collapsible urethral tube
|
US4737518A
(en)
|
1984-04-03 |
1988-04-12 |
Takeda Chemical Industries, Ltd. |
Lipid derivatives, their production and use
|
US4562596A
(en)
|
1984-04-25 |
1986-01-07 |
Elliot Kornberg |
Aortic graft, device and method for performing an intraluminal abdominal aortic aneurysm repair
|
US4782836A
(en)
|
1984-05-24 |
1988-11-08 |
Intermedics, Inc. |
Rate adaptive cardiac pacemaker responsive to patient activity and temperature
|
US4897355A
(en)
|
1985-01-07 |
1990-01-30 |
Syntex (U.S.A.) Inc. |
N[ω,(ω-1)-dialkyloxy]- and N-[ω,(ω-1)-dialkenyloxy]-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor
|
US4662382A
(en)
|
1985-01-16 |
1987-05-05 |
Intermedics, Inc. |
Pacemaker lead with enhanced sensitivity
|
US4762915A
(en)
|
1985-01-18 |
1988-08-09 |
Liposome Technology, Inc. |
Protein-liposome conjugates
|
US4860751A
(en)
|
1985-02-04 |
1989-08-29 |
Cordis Corporation |
Activity sensor for pacemaker control
|
US5223263A
(en)
|
1988-07-07 |
1993-06-29 |
Vical, Inc. |
Liponucleotide-containing liposomes
|
CA1320724C
(en)
|
1985-07-19 |
1993-07-27 |
Koichi Kanehira |
Terpene amino alcohols and medicinal uses thereof
|
US4701162A
(en)
|
1985-09-24 |
1987-10-20 |
The Kendall Company |
Foley catheter assembly
|
US4737323A
(en)
|
1986-02-13 |
1988-04-12 |
Liposome Technology, Inc. |
Liposome extrusion method
|
US5153319A
(en)
|
1986-03-31 |
1992-10-06 |
University Patents, Inc. |
Process for preparing polynucleotides
|
DE3616824A1
(de)
|
1986-05-17 |
1987-11-19 |
Schering Ag |
Verwendung von haertbaren kunstharzmischungen fuer oberflaechenbeschichtungen und druckfarben und verfahren zu ihrer herstellung
|
EP0255899B1
(de)
|
1986-07-31 |
1992-07-15 |
Werner Prof. Dr.-Ing. Irnich |
Frequenzadaptierender Herzschrittmacher
|
US4960409A
(en)
|
1986-09-11 |
1990-10-02 |
Catalano Marc L |
Method of using bilumen peripheral venous catheter with adapter
|
JPH0829776B2
(ja)
|
1986-10-29 |
1996-03-27 |
東燃化学株式会社 |
合成樹脂製容器及びその製造用金型
|
US4720517A
(en)
|
1986-11-24 |
1988-01-19 |
Ciba-Geigy Corporation |
Compositions stabilized with N-hydroxyiminodiacetic and dipropionic acids and esters thereof
|
US4920016A
(en)
|
1986-12-24 |
1990-04-24 |
Linear Technology, Inc. |
Liposomes with enhanced circulation time
|
DE3728917A1
(de)
|
1987-08-29 |
1989-03-09 |
Roth Hermann J |
Neue lipide mit unsymmetrisch substituierter disulfidbruecke
|
US4946683A
(en)
|
1987-11-18 |
1990-08-07 |
Vestar, Inc. |
Multiple step entrapment/loading procedure for preparing lipophilic drug-containing liposomes
|
US4843155A
(en)
*
|
1987-11-19 |
1989-06-27 |
Piotr Chomczynski |
Product and process for isolating RNA
|
US5138067A
(en)
|
1987-12-17 |
1992-08-11 |
Shionogi & Co. Ltd. |
Lipid derivatives
|
US5047540A
(en)
|
1987-12-17 |
1991-09-10 |
Shionogi & Co., Ltd. |
Lipid derivatives
|
JPH01257491A
(ja)
|
1988-04-08 |
1989-10-13 |
Tosoh Corp |
不溶性融合異種蛋白質の処理方法
|
US4892540A
(en)
|
1988-04-21 |
1990-01-09 |
Sorin Biomedica S.P.A. |
Two-leaflet prosthetic heart valve
|
US5176661A
(en)
|
1988-09-06 |
1993-01-05 |
Advanced Cardiovascular Systems, Inc. |
Composite vascular catheter
|
US5024671A
(en)
|
1988-09-19 |
1991-06-18 |
Baxter International Inc. |
Microporous vascular graft
|
US5200395A
(en)
|
1988-10-18 |
1993-04-06 |
Ajinomoto Company, Inc. |
Pharmaceutical composition of BUF-5 for treating anemia
|
CA2001401A1
(en)
|
1988-10-25 |
1990-04-25 |
Claude Piantadosi |
Quaternary amine containing ether or ester lipid derivatives and therapeutic compositions
|
US5262530A
(en)
|
1988-12-21 |
1993-11-16 |
Applied Biosystems, Inc. |
Automated system for polynucleotide synthesis and purification
|
US5047524A
(en)
|
1988-12-21 |
1991-09-10 |
Applied Biosystems, Inc. |
Automated system for polynucleotide synthesis and purification
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
US6214804B1
(en)
|
1989-03-21 |
2001-04-10 |
Vical Incorporated |
Induction of a protective immune response in a mammal by injecting a DNA sequence
|
FR2645866B1
(fr)
|
1989-04-17 |
1991-07-05 |
Centre Nat Rech Scient |
Nouvelles lipopolyamines, leur preparation et leur emploi
|
US5194654A
(en)
|
1989-11-22 |
1993-03-16 |
Vical, Inc. |
Lipid derivatives of phosphonoacids for liposomal incorporation and method of use
|
US5670488A
(en)
*
|
1992-12-03 |
1997-09-23 |
Genzyme Corporation |
Adenovirus vector for gene therapy
|
US20070053879A1
(en)
|
1990-03-05 |
2007-03-08 |
Genzyme Corporation |
Diagnostic and treatment methods involving the cystic fibrosis transmembrane regulator
|
US5279833A
(en)
|
1990-04-04 |
1994-01-18 |
Yale University |
Liposomal transfection of nucleic acids into animal cells
|
US5101824A
(en)
|
1990-04-16 |
1992-04-07 |
Siemens-Pacesetter, Inc. |
Rate-responsive pacemaker with circuitry for processing multiple sensor inputs
|
US5264618A
(en)
|
1990-04-19 |
1993-11-23 |
Vical, Inc. |
Cationic lipids for intracellular delivery of biologically active molecules
|
EP0549590A1
(en)
|
1990-07-26 |
1993-07-07 |
LANE, Rodney James |
Self expanding vascular endoprosthesis for aneurysms
|
US5693338A
(en)
|
1994-09-29 |
1997-12-02 |
Emisphere Technologies, Inc. |
Diketopiperazine-based delivery systems
|
JPH0765267B2
(ja)
|
1990-08-22 |
1995-07-12 |
花王株式会社 |
柔軟仕上剤
|
US5256294A
(en)
|
1990-09-17 |
1993-10-26 |
Genentech, Inc. |
Tangential flow filtration process and apparatus
|
ATE135555T1
(de)
|
1990-10-09 |
1996-04-15 |
Cook Inc |
Perkutane stentanordnung
|
DE59008908D1
(de)
|
1990-12-19 |
1995-05-18 |
Osypka Peter |
Herzschrittmacherleitung mit einem inneren Kanal und mit einem Elektrodenkopf.
|
US5116360A
(en)
|
1990-12-27 |
1992-05-26 |
Corvita Corporation |
Mesh composite graft
|
US5405363A
(en)
|
1991-03-15 |
1995-04-11 |
Angelon Corporation |
Implantable cardioverter defibrillator having a smaller displacement volume
|
US5330768A
(en)
|
1991-07-05 |
1994-07-19 |
Massachusetts Institute Of Technology |
Controlled drug delivery using polymer/pluronic blends
|
US5545449A
(en)
|
1991-10-02 |
1996-08-13 |
Weyerhaeuser Company |
Polyether-reinforced fiber-based materials
|
US5151105A
(en)
|
1991-10-07 |
1992-09-29 |
Kwan Gett Clifford |
Collapsible vessel sleeve implant
|
US5284491A
(en)
|
1992-02-27 |
1994-02-08 |
Medtronic, Inc. |
Cardiac pacemaker with hysteresis behavior
|
US5352461A
(en)
|
1992-03-11 |
1994-10-04 |
Pharmaceutical Discovery Corporation |
Self assembling diketopiperazine drug delivery system
|
SE9200951D0
(sv)
|
1992-03-27 |
1992-03-27 |
Kabi Pharmacia Ab |
Pharmaceutical composition containing a defined lipid system
|
DE69325096T2
(de)
|
1992-04-06 |
1999-09-30 |
Biosite Diagnostics Inc., San Diego |
Morphinderivate sowie deren konjugate und labels mit proteinen und polypeptiden
|
US6670178B1
(en)
|
1992-07-10 |
2003-12-30 |
Transkaryotic Therapies, Inc. |
In Vivo production and delivery of insulinotropin for gene therapy
|
EP0657534A4
(en)
|
1992-08-04 |
1997-06-04 |
Green Cross Corp |
ANTIALLERGIC AGENT.
|
US5334761A
(en)
|
1992-08-28 |
1994-08-02 |
Life Technologies, Inc. |
Cationic lipids
|
US5461223A
(en)
|
1992-10-09 |
1995-10-24 |
Eastman Kodak Company |
Bar code detecting circuitry
|
US5300022A
(en)
|
1992-11-12 |
1994-04-05 |
Martin Klapper |
Urinary catheter and bladder irrigation system
|
US5496362A
(en)
|
1992-11-24 |
1996-03-05 |
Cardiac Pacemakers, Inc. |
Implantable conformal coil patch electrode with multiple conductive elements for cardioversion and defibrillation
|
US5552155A
(en)
|
1992-12-04 |
1996-09-03 |
The Liposome Company, Inc. |
Fusogenic lipsomes and methods for making and using same
|
US5716395A
(en)
|
1992-12-11 |
1998-02-10 |
W.L. Gore & Associates, Inc. |
Prosthetic vascular graft
|
EP0685457B1
(en)
|
1993-02-19 |
1999-12-15 |
Nippon Shinyaku Company, Limited |
Glycerol derivative, device and pharmaceutical composition
|
US5395619A
(en)
|
1993-03-03 |
1995-03-07 |
Liposome Technology, Inc. |
Lipid-polymer conjugates and liposomes
|
US5697953A
(en)
|
1993-03-13 |
1997-12-16 |
Angeion Corporation |
Implantable cardioverter defibrillator having a smaller displacement volume
|
US5624976A
(en)
|
1994-03-25 |
1997-04-29 |
Dentsply Gmbh |
Dental filling composition and method
|
US5314430A
(en)
|
1993-06-24 |
1994-05-24 |
Medtronic, Inc. |
Atrial defibrillator employing transvenous and subcutaneous electrodes and method of use
|
DE4325848A1
(de)
|
1993-07-31 |
1995-02-02 |
Basf Ag |
Verfahren zur Herstellung von N-(2-Hydroxyethyl)-piperazin
|
EP1062999A3
(en)
|
1993-10-06 |
2001-03-14 |
The Kansai Electric Power Co., Inc. |
Method for removing carbon dioxide from combustion exhaust gas
|
US5609624A
(en)
|
1993-10-08 |
1997-03-11 |
Impra, Inc. |
Reinforced vascular graft and method of making same
|
SE9303481L
(sv)
|
1993-10-22 |
1995-04-23 |
Berol Nobel Ab |
Hygienkomposition
|
AU1091095A
(en)
|
1993-11-08 |
1995-05-29 |
Harrison M. Lazarus |
Intraluminal vascular graft and method
|
JPH09505593A
(ja)
|
1993-11-24 |
1997-06-03 |
メガバイオス・コーポレイション |
ピペラジンの両親媒性誘導体
|
US5595756A
(en)
|
1993-12-22 |
1997-01-21 |
Inex Pharmaceuticals Corporation |
Liposomal compositions for enhanced retention of bioactive agents
|
US5464924A
(en)
|
1994-01-07 |
1995-11-07 |
The Dow Chemical Company |
Flexible poly(amino ethers) for barrier packaging
|
EP0743950B1
(de)
|
1994-02-11 |
2001-12-12 |
QIAGEN GmbH |
Verfahren zur trennung von doppelstrang/einzelstrangnukleinsäurestrukturen
|
US5844107A
(en)
|
1994-03-23 |
1998-12-01 |
Case Western Reserve University |
Compacted nucleic acids and their delivery to cells
|
ATE234605T1
(de)
|
1994-04-12 |
2003-04-15 |
Liposome Co Inc |
Fusogene liposomen und verfahren zu deren herstellung und verwendung
|
US5840576A
(en)
|
1994-07-20 |
1998-11-24 |
Cytotherapeutics, Inc. |
Methods and compositions of growth control for cells encapsulated within bioartificial organs
|
US5885613A
(en)
|
1994-09-30 |
1999-03-23 |
The University Of British Columbia |
Bilayer stabilizing components and their use in forming programmable fusogenic liposomes
|
US5820873A
(en)
|
1994-09-30 |
1998-10-13 |
The University Of British Columbia |
Polyethylene glycol modified ceramide lipids and liposome uses thereof
|
US5641665A
(en)
|
1994-11-28 |
1997-06-24 |
Vical Incorporated |
Plasmids suitable for IL-2 expression
|
US6071890A
(en)
|
1994-12-09 |
2000-06-06 |
Genzyme Corporation |
Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy
|
US5965434A
(en)
|
1994-12-29 |
1999-10-12 |
Wolff; Jon A. |
Amphipathic PH sensitive compounds and delivery systems for delivering biologically active compounds
|
US6485726B1
(en)
|
1995-01-17 |
2002-11-26 |
The Brigham And Women's Hospital, Inc. |
Receptor specific transepithelial transport of therapeutics
|
US5830430A
(en)
|
1995-02-21 |
1998-11-03 |
Imarx Pharmaceutical Corp. |
Cationic lipids and the use thereof
|
JP2001523215A
(ja)
|
1995-04-17 |
2001-11-20 |
イマークス ファーマシューティカル コーポレーション |
ハイブリッド磁気共鳴造影剤
|
US20010047091A1
(en)
|
1998-09-09 |
2001-11-29 |
Brian Miki |
Cryptic regulatory elements obtained from plants
|
US5772694A
(en)
|
1995-05-16 |
1998-06-30 |
Medical Carbon Research Institute L.L.C. |
Prosthetic heart valve with improved blood flow
|
US5700642A
(en)
|
1995-05-22 |
1997-12-23 |
Sri International |
Oligonucleotide sizing using immobilized cleavable primers
|
US5783383A
(en)
|
1995-05-23 |
1998-07-21 |
The Board Of Trustees Of The Leland Stanford Junior University |
Method of detecting cytomegalovirus (CMV)
|
US7422902B1
(en)
|
1995-06-07 |
2008-09-09 |
The University Of British Columbia |
Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer
|
US5609629A
(en)
|
1995-06-07 |
1997-03-11 |
Med Institute, Inc. |
Coated implantable medical device
|
US5705385A
(en)
|
1995-06-07 |
1998-01-06 |
Inex Pharmaceuticals Corporation |
Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer
|
EP0832271B8
(en)
|
1995-06-07 |
2005-03-02 |
INEX Pharmaceuticals Corp. |
Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer
|
US5981501A
(en)
|
1995-06-07 |
1999-11-09 |
Inex Pharmaceuticals Corp. |
Methods for encapsulating plasmids in lipid bilayers
|
US5607385A
(en)
|
1995-08-17 |
1997-03-04 |
Medtronic, Inc. |
Device and algorithm for a combined cardiomyostimulator and a cardiac pacer-carioverter-defibrillator
|
US5744335A
(en)
|
1995-09-19 |
1998-04-28 |
Mirus Corporation |
Process of transfecting a cell with a polynucleotide mixed with an amphipathic compound and a DNA-binding protein
|
FR2740978B1
(fr)
|
1995-11-10 |
1998-01-02 |
Ela Medical Sa |
Dispositif medical actif du type defibrillateur/cardioverteur implantable
|
US5874105A
(en)
|
1996-01-31 |
1999-02-23 |
Collaborative Laboratories, Inc. |
Lipid vesicles formed with alkylammonium fatty acid salts
|
EP0910576B1
(en)
|
1996-04-11 |
2004-08-11 |
University Of British Columbia |
Fusogenic liposomes
|
US5935936A
(en)
|
1996-06-03 |
1999-08-10 |
Genzyme Corporation |
Compositions comprising cationic amphiphiles and co-lipids for intracellular delivery of therapeutic molecules
|
US5913848A
(en)
|
1996-06-06 |
1999-06-22 |
Luther Medical Products, Inc. |
Hard tip over-the-needle catheter and method of manufacturing the same
|
US5677124A
(en)
|
1996-07-03 |
1997-10-14 |
Ambion, Inc. |
Ribonuclease resistant viral RNA standards
|
US5736573A
(en)
|
1996-07-31 |
1998-04-07 |
Galat; Alexander |
Lipid and water soluble derivatives of drugs
|
US6011148A
(en)
*
|
1996-08-01 |
2000-01-04 |
Megabios Corporation |
Methods for purifying nucleic acids
|
US7288266B2
(en)
|
1996-08-19 |
2007-10-30 |
United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Liposome complexes for increased systemic delivery
|
DE69725877T2
(de)
|
1996-08-26 |
2004-07-22 |
Transgene S.A. |
Kationische lipid-nukleinsäure komplexe
|
ATE395904T1
(de)
|
1996-09-13 |
2008-06-15 |
Lipoxen Technologies Ltd |
Liposome
|
US5874268A
(en)
|
1996-09-23 |
1999-02-23 |
Duke University |
Method of introducing exogenous compounds into cells by electroporation and apparatus for same
|
TW520297B
(en)
|
1996-10-11 |
2003-02-11 |
Sequus Pharm Inc |
Fusogenic liposome composition and method
|
EP1003556B1
(en)
|
1996-11-04 |
2006-03-01 |
Qiagen GmbH |
Cationic reagents for transfection
|
US6887665B2
(en)
|
1996-11-14 |
2005-05-03 |
Affymetrix, Inc. |
Methods of array synthesis
|
US5985930A
(en)
|
1996-11-21 |
1999-11-16 |
Pasinetti; Giulio M. |
Treatment of neurodegenerative conditions with nimesulide
|
US6204297B1
(en)
|
1996-11-26 |
2001-03-20 |
Rhodia Inc. |
Nonionic gemini surfactants
|
JPH10197978A
(ja)
|
1997-01-09 |
1998-07-31 |
Mitsubishi Paper Mills Ltd |
ハロゲン化銀写真感光材料
|
EP0853123A1
(de)
*
|
1997-01-10 |
1998-07-15 |
Roche Diagnostics GmbH |
Reinigung von DNA durch Cross-Flow-Filtration
|
FR2760193B1
(fr)
|
1997-02-28 |
1999-05-28 |
Transgene Sa |
Lipides et complexes de lipides cationiques et de substances actives, notamment pour la transfection de cellules
|
US5837283A
(en)
|
1997-03-12 |
1998-11-17 |
The Regents Of The University Of California |
Cationic lipid compositions targeting angiogenic endothelial cells
|
US5945326A
(en)
|
1997-03-20 |
1999-08-31 |
New England Biolabs, Inc. |
Method for cloning and producing the Spel restriction endonuclease
|
US6835395B1
(en)
|
1997-05-14 |
2004-12-28 |
The University Of British Columbia |
Composition containing small multilamellar oligodeoxynucleotide-containing lipid vesicles
|
WO1998051278A2
(en)
|
1997-05-14 |
1998-11-19 |
Inex Pharmaceuticals Corporation |
High efficiency encapsulation of charged therapeutic agents in lipid vesicles
|
US20030104044A1
(en)
|
1997-05-14 |
2003-06-05 |
Semple Sean C. |
Compositions for stimulating cytokine secretion and inducing an immune response
|
AU8623798A
(en)
|
1997-06-02 |
1998-12-21 |
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw |
Smad-interacting polypeptides and their use
|
JPH115786A
(ja)
|
1997-06-13 |
1999-01-12 |
Pola Chem Ind Inc |
新規アミノヒドロキシプロピルピペラジン誘導体
|
US6067471A
(en)
|
1998-08-07 |
2000-05-23 |
Cardiac Pacemakers, Inc. |
Atrial and ventricular implantable cardioverter-defibrillator and lead system
|
JPH1180142A
(ja)
|
1997-09-05 |
1999-03-26 |
Pola Chem Ind Inc |
ジフェニルアルキル化合物の製造法
|
US20030083272A1
(en)
|
1997-09-19 |
2003-05-01 |
Lahive & Cockfield, Llp |
Sense mrna therapy
|
US6165763A
(en)
|
1997-10-30 |
2000-12-26 |
Smithkline Beecham Corporation |
Ornithine carbamoyltransferase
|
US6096075A
(en)
|
1998-01-22 |
2000-08-01 |
Medical Carbon Research Institute, Llc |
Prosthetic heart valve
|
US6617171B2
(en)
|
1998-02-27 |
2003-09-09 |
The General Hospital Corporation |
Methods for diagnosing and treating autoimmune disease
|
US6271209B1
(en)
|
1998-04-03 |
2001-08-07 |
Valentis, Inc. |
Cationic lipid formulation delivering nucleic acid to peritoneal tumors
|
US6176877B1
(en)
|
1998-04-20 |
2001-01-23 |
St. Jude Medical, Inc. |
Two piece prosthetic heart valve
|
US6986902B1
(en)
|
1998-04-28 |
2006-01-17 |
Inex Pharmaceuticals Corporation |
Polyanionic polymers which enhance fusogenicity
|
DE19822602A1
(de)
|
1998-05-20 |
1999-11-25 |
Goldschmidt Ag Th |
Verfahren zur Herstellung von Polyaminosäureestern durch Veresterung von sauren Polyaminosäuren oder Umesterung von Polyaminosäureestern
|
NO313244B1
(no)
|
1998-07-08 |
2002-09-02 |
Crew Dev Corp |
Fremgangsmåte for isolering og produksjon av magnesitt eller magnesiumklorid
|
US6055454A
(en)
|
1998-07-27 |
2000-04-25 |
Cardiac Pacemakers, Inc. |
Cardiac pacemaker with automatic response optimization of a physiologic sensor based on a second sensor
|
WO2000010622A1
(en)
|
1998-08-20 |
2000-03-02 |
Cook Incorporated |
Coated implantable medical device
|
US6210892B1
(en)
|
1998-10-07 |
2001-04-03 |
Isis Pharmaceuticals, Inc. |
Alteration of cellular behavior by antisense modulation of mRNA processing
|
AU1830200A
(en)
|
1998-11-25 |
2000-06-13 |
Vanderbilt University |
Cationic liposomes for gene transfer
|
US6740643B2
(en)
|
1999-01-21 |
2004-05-25 |
Mirus Corporation |
Compositions and methods for drug delivery using amphiphile binding molecules
|
US6248725B1
(en)
|
1999-02-23 |
2001-06-19 |
Amgen, Inc. |
Combinations and methods for promoting in vivo liver cell proliferation and enhancing in vivo liver-directed gene transduction
|
US6379698B1
(en)
|
1999-04-06 |
2002-04-30 |
Isis Pharmaceuticals, Inc. |
Fusogenic lipids and vesicles
|
WO2000062813A2
(en)
|
1999-04-20 |
2000-10-26 |
The University Of British Columbia |
Cationic peg-lipids and methods of use
|
US6169923B1
(en)
|
1999-04-23 |
2001-01-02 |
Pacesetter, Inc. |
Implantable cardioverter-defibrillator with automatic arrhythmia detection criteria adjustment
|
HUP0200797A3
(en)
|
1999-04-23 |
2010-01-28 |
Alza Corp |
Releasable linkage and compositions containing same
|
CZ20014123A3
(cs)
|
1999-05-19 |
2002-06-12 |
Lexigen Pharmaceuticals Corp. |
Exprese a export interferonů-alfa jako Fc fúzních proteinů
|
US6696424B1
(en)
|
1999-05-28 |
2004-02-24 |
Vical Incorporated |
Cytofectin dimers and methods of use thereof
|
US6346382B1
(en)
|
1999-06-01 |
2002-02-12 |
Vanderbilt University |
Human carbamyl phosphate synthetase I polymorphism and diagnostic methods related thereto
|
WO2001005375A1
(en)
|
1999-07-16 |
2001-01-25 |
Purdue Research Foundation |
Vinyl ether lipids with cleavable hydrophilic headgroups
|
HUP0202295A3
(en)
|
1999-07-23 |
2005-01-28 |
Genentech Inc |
Method for rnase- and organic solvent-free plasmid dna purification using tangential flow filtration
|
US6358278B1
(en)
|
1999-09-24 |
2002-03-19 |
St. Jude Medical, Inc. |
Heart valve prosthesis with rotatable cuff
|
US6371983B1
(en)
|
1999-10-04 |
2002-04-16 |
Ernest Lane |
Bioprosthetic heart valve
|
US7060291B1
(en)
|
1999-11-24 |
2006-06-13 |
Transave, Inc. |
Modular targeted liposomal delivery system
|
AU3366901A
(en)
|
1999-12-30 |
2001-07-16 |
Novartis Ag |
Novel colloid synthetic vectors for gene therapy
|
JP2003533437A
(ja)
|
2000-02-17 |
2003-11-11 |
ジェンザイム・コーポレイション |
遺伝子デリバリーのための門戸としての肺の遺伝的修飾
|
US6370434B1
(en)
|
2000-02-28 |
2002-04-09 |
Cardiac Pacemakers, Inc. |
Cardiac lead and method for lead implantation
|
WO2001085974A2
(en)
|
2000-05-12 |
2001-11-15 |
University Of Southern California |
Retroviral vectors comprising an enhanced 3' transcription termination structure
|
US6565960B2
(en)
|
2000-06-01 |
2003-05-20 |
Shriners Hospital Of Children |
Polymer composite compositions
|
IL138474A0
(en)
|
2000-09-14 |
2001-10-31 |
Epox Ltd |
Highly branched water-soluble polyamine oligomers, process for their preparation and applications thereof
|
USRE43612E1
(en)
|
2000-10-10 |
2012-08-28 |
Massachusetts Institute Of Technology |
Biodegradable poly(β-amino esters) and uses thereof
|
US6998115B2
(en)
|
2000-10-10 |
2006-02-14 |
Massachusetts Institute Of Technology |
Biodegradable poly(β-amino esters) and uses thereof
|
US7427394B2
(en)
|
2000-10-10 |
2008-09-23 |
Massachusetts Institute Of Technology |
Biodegradable poly(β-amino esters) and uses thereof
|
US7202226B2
(en)
|
2000-10-23 |
2007-04-10 |
Detroit R & D |
Augmentation of wound healing by elF-4E mRNA and EGF mRNA
|
CA2426244A1
(en)
|
2000-10-25 |
2002-05-02 |
The University Of British Columbia |
Lipid formulations for target delivery
|
GB0028361D0
(en)
*
|
2000-11-21 |
2001-01-03 |
Glaxo Group Ltd |
Method of separating extra chromosomal dna from other cellular components
|
US20020094528A1
(en)
|
2000-11-29 |
2002-07-18 |
Salafsky Joshua S. |
Method and apparatus using a surface-selective nonlinear optical technique for detection of probe-target interations
|
JP2002167368A
(ja)
|
2000-12-01 |
2002-06-11 |
Nitto Denko Corp |
アルキル置換デンドリマーおよびその製造法
|
US20050004058A1
(en)
|
2000-12-07 |
2005-01-06 |
Patrick Benoit |
Sequences upstream of the carp gene, vectors containing them and uses thereof
|
JP4061043B2
(ja)
|
2000-12-28 |
2008-03-12 |
株式会社ポストゲノム研究所 |
invitro転写/翻訳系によるペプチド等の製造方法
|
CA2437737A1
(en)
|
2001-02-14 |
2002-08-22 |
Stephen D. Ginsberg |
Methods and compositions of amplifying rna
|
DE10109897A1
(de)
|
2001-02-21 |
2002-11-07 |
Novosom Ag |
Fakultativ kationische Liposomen und Verwendung dieser
|
US20020192721A1
(en)
|
2001-03-28 |
2002-12-19 |
Engeneos, Inc. |
Modular molecular clasps and uses thereof
|
KR100823815B1
(ko)
|
2001-04-23 |
2008-04-21 |
신에쓰 가가꾸 고교 가부시끼가이샤 |
에스테르 구조를 갖는 신규 3급 아민 화합물 및 그 제조방법
|
US6585410B1
(en)
|
2001-05-03 |
2003-07-01 |
The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration |
Radiant temperature nulling radiometer
|
ES2340499T3
(es)
|
2001-06-05 |
2010-06-04 |
Curevac Gmbh |
Arnm de antigeno tumoral estabilizado con un contenido de g/c aumentado.
|
IL161100A0
(en)
|
2001-09-28 |
2004-08-31 |
Max Planck Gesellschaft |
Identification of novel genes coding for small temporal rnas
|
EP1438426A1
(en)
|
2001-10-12 |
2004-07-21 |
Gentra Systems Inc. |
Compositions and methods for using a solid support to purify rna
|
US7132295B2
(en)
|
2001-11-09 |
2006-11-07 |
Bayer Aktiengesellschaft |
Isotopically coded affinity markers 3
|
DE10162480A1
(de)
|
2001-12-19 |
2003-08-07 |
Ingmar Hoerr |
Die Applikation von mRNA für den Einsatz als Therapeutikum gegen Tumorerkrankungen
|
DE10207178A1
(de)
|
2002-02-19 |
2003-09-04 |
Novosom Ag |
Komponenten für die Herstellung amphoterer Liposomen
|
AU2003220249A1
(en)
*
|
2002-03-15 |
2003-09-29 |
Arcturus Bioscience, Inc. |
Improved nucleic acid amplification
|
DE10214983A1
(de)
|
2002-04-04 |
2004-04-08 |
TransMIT Gesellschaft für Technologietransfer mbH |
Vernebelbare Liposomen und ihre Verwendung zur pulmonalen Applikation von Wirkstoffen
|
GB0208390D0
(en)
|
2002-04-11 |
2002-05-22 |
Univ London |
Adeno-associated virus producer system
|
US20030215395A1
(en)
|
2002-05-14 |
2003-11-20 |
Lei Yu |
Controllably degradable polymeric biomolecule or drug carrier and method of synthesizing said carrier
|
US7601367B2
(en)
|
2002-05-28 |
2009-10-13 |
Mirus Bio Llc |
Compositions and processes using siRNA, amphipathic compounds and polycations
|
DK1519714T3
(da)
|
2002-06-28 |
2011-01-31 |
Protiva Biotherapeutics Inc |
Fremgangsmåde og apparat til fremstilling af liposomer
|
DE10229872A1
(de)
|
2002-07-03 |
2004-01-29 |
Curevac Gmbh |
Immunstimulation durch chemisch modifizierte RNA
|
US20040028804A1
(en)
|
2002-08-07 |
2004-02-12 |
Anderson Daniel G. |
Production of polymeric microarrays
|
AU2003260724A1
(en)
|
2002-08-22 |
2004-03-11 |
Celltran Limited |
Cell culture surface
|
US20060160759A1
(en)
|
2002-09-28 |
2006-07-20 |
Jianzhu Chen |
Influenza therapeutic
|
EP1565512B1
(de)
|
2002-11-04 |
2018-07-04 |
Momentive Performance Materials GmbH |
Lineare polyamino- und/oder polyammonium-polysiloxancopolymere i
|
EP1572669A2
(en)
|
2002-11-22 |
2005-09-14 |
Novo Nordisk A/S |
2,5-diketopiperazines for the treatment of obesity
|
US7169892B2
(en)
|
2003-01-10 |
2007-01-30 |
Astellas Pharma Inc. |
Lipid-peptide-polymer conjugates for long blood circulation and tumor specific drug delivery systems
|
WO2004066138A1
(ja)
|
2003-01-20 |
2004-08-05 |
Asahi Kasei Emd Corporation |
ポインティングデバイス
|
EP1601788A4
(en)
|
2003-02-24 |
2006-11-15 |
Gtc Biotherapeutics Inc |
METHOD OF TANGENTIAL ELECTRIC FILTRATION AND DEVICE THEREFOR
|
CA2517974A1
(en)
|
2003-03-05 |
2004-09-16 |
Senesco Technologies, Inc. |
Use of antisense oligonucleotides or sirna to suppress expression of eif-5a1
|
US20040224912A1
(en)
|
2003-05-07 |
2004-11-11 |
Isis Pharmaceuticals Inc. |
Modulation of PAI-1 mRNA-binding protein expression
|
US7619017B2
(en)
|
2003-05-19 |
2009-11-17 |
Wacker Chemical Corporation |
Polymer emulsions resistant to biodeterioration
|
WO2005007810A2
(en)
|
2003-06-16 |
2005-01-27 |
Grinstaff Mark W |
Functional synthetic molecules and macromolecules for gene delivery
|
US20050059024A1
(en)
|
2003-07-25 |
2005-03-17 |
Ambion, Inc. |
Methods and compositions for isolating small RNA molecules
|
EP1664316B1
(en)
|
2003-09-15 |
2012-08-29 |
Protiva Biotherapeutics Inc. |
Polyethyleneglycol-modified lipid compounds and uses thereof
|
WO2005028619A2
(en)
|
2003-09-15 |
2005-03-31 |
Massachusetts Institute Of Technology |
Nanoliter-scale synthesis of arrayed biomaterials and screening thereof
|
US20050069590A1
(en)
|
2003-09-30 |
2005-03-31 |
Buehler Gail K. |
Stable suspensions for medicinal dosages
|
MXPA06003978A
(es)
|
2003-10-10 |
2006-06-27 |
Powderject Vaccines Inc |
Constructos de acidos nucleicos.
|
WO2005037226A2
(en)
|
2003-10-17 |
2005-04-28 |
Georgia Tech Research Corporation |
Genetically engineered enteroendocrine cells for treating glucose-related metabolic disorders
|
EP1683784A4
(en)
|
2003-11-10 |
2007-08-22 |
Nippon Kayaku Kk |
DIIMONIUM SALT CONNECTION AND ITS USE
|
US8075780B2
(en)
*
|
2003-11-24 |
2011-12-13 |
Millipore Corporation |
Purification and concentration of synthetic biological molecules
|
ATE466080T1
(de)
*
|
2003-12-16 |
2010-05-15 |
Qiagen North American Holdings |
Formulierungen und verfahren zum denaturieren von proteinen
|
US7022214B2
(en)
|
2004-01-21 |
2006-04-04 |
Bio-Rad Laboratories, Inc. |
Carrier ampholytes of high pH range
|
US7556684B2
(en)
|
2004-02-26 |
2009-07-07 |
Construction Research & Technology Gmbh |
Amine containing strength improvement admixture
|
US20060228404A1
(en)
|
2004-03-04 |
2006-10-12 |
Anderson Daniel G |
Compositions and methods for treatment of hypertrophic tissues
|
JP2006271201A
(ja)
*
|
2004-03-26 |
2006-10-12 |
Fuji Photo Film Co Ltd |
Rnaの選択的分離精製方法
|
US7824855B2
(en)
|
2004-03-26 |
2010-11-02 |
Fujifilm Corporation |
Method for selectively separating and purifying RNA and method for separating and purifying nucleic acid
|
EP1766035B1
(en)
|
2004-06-07 |
2011-12-07 |
Protiva Biotherapeutics Inc. |
Lipid encapsulated interfering rna
|
ATE537263T1
(de)
|
2004-06-07 |
2011-12-15 |
Protiva Biotherapeutics Inc |
Kationische lipide und verwendungsverfahren
|
US7670595B2
(en)
|
2004-06-28 |
2010-03-02 |
Merck Patent Gmbh |
Fc-interferon-beta fusion proteins
|
GB0418172D0
(en)
|
2004-08-13 |
2004-09-15 |
Ic Vec Ltd |
Vector
|
US7361465B2
(en)
|
2004-09-07 |
2008-04-22 |
Applera Corporation |
Methods and compositions for tailing and amplifying RNA
|
DE102004043342A1
(de)
|
2004-09-08 |
2006-03-09 |
Bayer Materialscience Ag |
Blockierte Polyurethan-Prepolymere als Klebstoffe
|
AU2005300638A1
(en)
|
2004-11-05 |
2006-05-11 |
Novosom Ag |
Improvements in or relating to pharmaceutical compositions comprising an oligonucleotide as an active agent
|
CN101310022B
(zh)
*
|
2005-01-31 |
2013-01-16 |
默沙东公司 |
大规模生产质粒dna的上游和下游纯化方法
|
GB0502482D0
(en)
|
2005-02-07 |
2005-03-16 |
Glaxo Group Ltd |
Novel compounds
|
WO2007086881A2
(en)
|
2005-02-14 |
2007-08-02 |
Sirna Therapeutics, Inc. |
Cationic lipids and formulated molecular compositions containing them
|
EP1869106B1
(en)
|
2005-03-28 |
2014-06-25 |
Dendritic Nanotechnologies, Inc. |
Janus dendrimers and dendrons
|
JP5777846B2
(ja)
|
2005-06-15 |
2015-09-09 |
マサチューセッツ インスティテュート オブ テクノロジー |
アミン含有脂質およびその使用
|
CA2617981A1
(en)
|
2005-08-05 |
2007-02-15 |
Pfizer Products Inc. |
Automated batch manufacturing
|
US9012219B2
(en)
|
2005-08-23 |
2015-04-21 |
The Trustees Of The University Of Pennsylvania |
RNA preparations comprising purified modified RNA for reprogramming cells
|
PL2578685T3
(pl)
|
2005-08-23 |
2020-01-31 |
The Trustees Of The University Of Pennsylvania |
Rna zawierający zmodyfikowane nukleozydy i sposoby jego zastosowania
|
WO2007031091A2
(en)
|
2005-09-15 |
2007-03-22 |
Santaris Pharma A/S |
Rna antagonist compounds for the modulation of p21 ras expression
|
EP2395012B8
(en)
|
2005-11-02 |
2018-06-06 |
Arbutus Biopharma Corporation |
Modified siRNA molecules and uses thereof
|
US7238791B1
(en)
|
2005-12-16 |
2007-07-03 |
Roche Diagnostics Operations, Inc. |
6-monoacetylmorphine derivatives useful in immunoassay
|
WO2007073489A2
(en)
|
2005-12-22 |
2007-06-28 |
Trustees Of Boston University |
Molecules for gene delivery and gene therapy, and methods of use thereof
|
CN100569877C
(zh)
|
2005-12-30 |
2009-12-16 |
财团法人工业技术研究院 |
含多uv交联反应基的分枝状结构化合物及其应用
|
US20070281336A1
(en)
|
2006-04-14 |
2007-12-06 |
Epicentre Technologies |
Kits and methods for generating 5' capped RNA
|
US9085778B2
(en)
|
2006-05-03 |
2015-07-21 |
VL27, Inc. |
Exosome transfer of nucleic acids to cells
|
US20070275923A1
(en)
|
2006-05-25 |
2007-11-29 |
Nastech Pharmaceutical Company Inc. |
CATIONIC PEPTIDES FOR siRNA INTRACELLULAR DELIVERY
|
US8808681B2
(en)
|
2006-06-05 |
2014-08-19 |
Massachusetts Institute Of Technology |
Crosslinked, degradable polymers and uses thereof
|
US20080102493A1
(en)
|
2006-06-29 |
2008-05-01 |
Millipore Corporation |
Isolation of RNA and DNA from a biological sample
|
US20090186805A1
(en)
|
2006-07-06 |
2009-07-23 |
Aaron Thomas Tabor |
Compositions and Methods for Genetic Modification of Cells Having Cosmetic Function to Enhance Cosmetic Appearance
|
ES2293834B1
(es)
|
2006-07-20 |
2009-02-16 |
Consejo Superior Investig. Cientificas |
Compuesto con actividad inhibidora de las interacciones ubc13-uev, composiciones farmaceuticas que lo comprenden y sus aplicaciones terapeuticas.
|
CA2658768C
(en)
|
2006-07-21 |
2016-05-17 |
Massachusetts Institute Of Technology |
End-modified poly(beta-amino esters) and uses thereof
|
KR101129509B1
(ko)
|
2006-10-03 |
2012-04-13 |
알닐람 파마슈티칼스 인코포레이티드 |
지질 함유 조성물
|
DE102006051516A1
(de)
|
2006-10-31 |
2008-05-08 |
Curevac Gmbh |
(Basen-)modifizierte RNA zur Expressionssteigerung eines Proteins
|
EP2104739B1
(en)
|
2006-12-21 |
2013-06-19 |
Novozymes Inc. |
Modified messenger rna stabilizing sequences for expressing genes in bacterial cells
|
DE102007001370A1
(de)
|
2007-01-09 |
2008-07-10 |
Curevac Gmbh |
RNA-kodierte Antikörper
|
EP2125030A2
(en)
|
2007-01-29 |
2009-12-02 |
Medipol S.A. |
Chitosan-based colloidal particles for rna delivery
|
US8859229B2
(en)
|
2007-02-02 |
2014-10-14 |
Yale University |
Transient transfection with RNA
|
EP2139461A2
(en)
|
2007-03-20 |
2010-01-06 |
Recepticon Aps |
Amino derivatives to prevent nephrotoxicity and cancer
|
JP5186126B2
(ja)
|
2007-03-29 |
2013-04-17 |
公益財団法人地球環境産業技術研究機構 |
新規トリアジン誘導体ならびにその製法およびそのガス分離膜としての用途
|
WO2008131114A2
(en)
|
2007-04-18 |
2008-10-30 |
Cornerstone Pharmaceuticals, Inc. |
Pharmaceutical formulations containing lipoic acid derivatives
|
US8678686B2
(en)
|
2007-05-01 |
2014-03-25 |
Pgr-Solutions |
Multi-chain lipophilic polyamines
|
US20090163705A1
(en)
|
2007-05-21 |
2009-06-25 |
Alnylam Pharmaceuticals, Inc. |
Cationic lipids
|
JP5697450B2
(ja)
|
2007-10-02 |
2015-04-08 |
マリーナ バイオテック,インコーポレイテッド |
核酸の送達のためのリポペプチド
|
US20090247608A1
(en)
|
2007-12-04 |
2009-10-01 |
Alnylam Pharmaceuticals, Inc. |
Targeting Lipids
|
ES2535419T3
(es)
|
2007-12-27 |
2015-05-11 |
Protiva Biotherapeutics Inc. |
Silenciamiento de expresión de quinasa tipo polo usando ARN interferente
|
WO2009120247A2
(en)
|
2007-12-27 |
2009-10-01 |
The Ohio State University Research Foundation |
Lipid nanoparticle compositions and methods of making and using the same
|
US20110097720A1
(en)
|
2008-01-02 |
2011-04-28 |
Alnylam Pharmaceuticals, Inc. |
Screening method for selected amino lipid-containing compositions
|
FR2926560A1
(fr)
|
2008-01-21 |
2009-07-24 |
Millipore Corp |
Procede d'extraction et de purification d'acides nucleiques sur membrane
|
JP5788312B2
(ja)
|
2008-04-11 |
2015-09-30 |
アルニラム ファーマスーティカルズ インコーポレイテッドAlnylam Pharmaceuticals, Inc. |
標的リガンドをエンドソーム分解性成分と組み合わせることによる核酸の部位特異的送達
|
PL2279254T3
(pl)
|
2008-04-15 |
2017-11-30 |
Protiva Biotherapeutics Inc. |
Nowe preparaty lipidowe do dostarczania kwasów nukleinowych
|
US20090263407A1
(en)
|
2008-04-16 |
2009-10-22 |
Abbott Laboratories |
Cationic Lipids and Uses Thereof
|
WO2009127230A1
(en)
|
2008-04-16 |
2009-10-22 |
Curevac Gmbh |
MODIFIED (m)RNA FOR SUPPRESSING OR AVOIDING AN IMMUNOSTIMULATORY RESPONSE AND IMMUNOSUPPRESSIVE COMPOSITION
|
AU2009256243A1
(en)
|
2008-06-04 |
2009-12-10 |
The Board Of Regents Of The University Of Texas System |
Modulation of gene expression through endogenous small RNA targeting of gene promoters
|
US20100012012A1
(en)
|
2008-07-19 |
2010-01-21 |
Mark Schaefbauer |
Positioning apparatus
|
JP5024216B2
(ja)
|
2008-07-23 |
2012-09-12 |
トヨタ自動車株式会社 |
内燃機関の点火時期制御装置及び点火時期制御方法
|
US20100035249A1
(en)
|
2008-08-05 |
2010-02-11 |
Kabushiki Kaisha Dnaform |
Rna sequencing and analysis using solid support
|
WO2010025302A2
(en)
|
2008-08-27 |
2010-03-04 |
Life Technologies Corporation |
Apparatus for and method of processing biological samples
|
JP2010053108A
(ja)
*
|
2008-08-29 |
2010-03-11 |
Asahi Kasei Corp |
荷電を有する限外濾過膜を用いた生体成分の分離方法およびモジュール、装置
|
WO2010037408A1
(en)
|
2008-09-30 |
2010-04-08 |
Curevac Gmbh |
Composition comprising a complexed (m)rna and a naked mrna for providing or enhancing an immunostimulatory response in a mammal and uses thereof
|
CA2984026C
(en)
|
2008-10-09 |
2020-02-11 |
Arbutus Biopharma Corporation |
Improved amino lipids and methods for the delivery of nucleic acids
|
EP2349210B1
(en)
|
2008-10-16 |
2015-03-18 |
Marina Biotech, Inc. |
Processes and compositions for liposomal and efficient delivery of gene silencing therapeutics
|
US9080211B2
(en)
|
2008-10-24 |
2015-07-14 |
Epicentre Technologies Corporation |
Transposon end compositions and methods for modifying nucleic acids
|
WO2010062322A2
(en)
|
2008-10-27 |
2010-06-03 |
Massachusetts Institute Of Technology |
Modulation of the immune response
|
US8588371B2
(en)
|
2008-11-05 |
2013-11-19 |
Hitachi Medical Corporation |
Phase shift inverter, X-ray high-voltage device using same, X-ray CT device, and X-ray imaging device
|
US8969353B2
(en)
|
2008-11-07 |
2015-03-03 |
Massachusetts Institute Of Technology |
Aminoalcohol lipidoids and uses thereof
|
JP5774486B2
(ja)
|
2008-11-10 |
2015-09-09 |
テクミラ ファーマシューティカルズ コーポレイションTekmira Pharmaceuticals Corporation |
治療薬を送達するための新規な脂質及び組成物
|
CN102216462A
(zh)
|
2008-11-17 |
2011-10-12 |
安龙制药公司 |
用于核酸递送系统的支化阳离子脂质
|
US20110236391A1
(en)
|
2008-12-09 |
2011-09-29 |
Hanns-Christian Mahler |
Method for obtaining an excipient-free antibody solution
|
US9023820B2
(en)
|
2009-01-26 |
2015-05-05 |
Protiva Biotherapeutics, Inc. |
Compositions and methods for silencing apolipoprotein C-III expression
|
US20100222489A1
(en)
|
2009-02-27 |
2010-09-02 |
Jiang Dayue D |
Copolymer composition, membrane article, and methods thereof
|
EP2406376A1
(en)
|
2009-03-12 |
2012-01-18 |
Alnylam Pharmaceuticals, Inc. |
LIPID FORMULATED COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF Eg5 AND VEGF GENES
|
EP2415124B1
(en)
|
2009-04-02 |
2017-02-15 |
The Siemon Company |
Telecommunications patch panel
|
ES2749393T3
(es)
|
2009-04-17 |
2020-03-20 |
Univ Oxford Innovation Ltd |
Composición para entrega de material genético
|
EP2421563B1
(en)
|
2009-04-22 |
2017-04-12 |
Massachusetts Institute of Technology |
Innate immune suppression enables repeated delivery of long rna molecules
|
KR20240015723A
(ko)
|
2009-05-05 |
2024-02-05 |
알닐람 파마슈티칼스 인코포레이티드 |
지질 조성물
|
CN102625696B
(zh)
|
2009-06-10 |
2015-06-03 |
阿尔尼拉姆医药品有限公司 |
改进的脂质制剂
|
WO2010147992A1
(en)
|
2009-06-15 |
2010-12-23 |
Alnylam Pharmaceuticals, Inc. |
Methods for increasing efficacy of lipid formulated sirna
|
EP2442792A4
(en)
|
2009-06-15 |
2015-12-23 |
Alnylam Pharmaceuticals Inc |
DOUBLE STRANDED RNA IN LIPID FORMULATION TARGETING THE PCSK9 GENE
|
US9018187B2
(en)
|
2009-07-01 |
2015-04-28 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods for the delivery of therapeutic agents
|
WO2011000106A1
(en)
|
2009-07-01 |
2011-01-06 |
Protiva Biotherapeutics, Inc. |
Improved cationic lipids and methods for the delivery of therapeutic agents
|
WO2011000108A1
(en)
|
2009-07-01 |
2011-01-06 |
Protiva Biotherapeutics, Inc. |
Compositions and methods for silencing apolipoprotein b
|
WO2011011447A1
(en)
|
2009-07-20 |
2011-01-27 |
Protiva Biotherapeutics, Inc. |
Compositions and methods for silencing ebola virus gene expression
|
IN2012DN01378A
(ru)
|
2009-07-30 |
2015-06-05 |
Salvat Lab Sa |
|
DK2459231T3
(en)
|
2009-07-31 |
2016-09-05 |
Ethris Gmbh |
RNA with a combination of unmodified and modified nucleotides for protein expression
|
CA2771597C
(en)
|
2009-08-19 |
2018-01-09 |
National University Corporation NARA Institute of Science and Technology |
Recombinant dna molecule encoding 5'utr capable of preventing inhibition of translation under environmental stresses
|
DE102009043342A1
(de)
|
2009-09-29 |
2011-03-31 |
Bayer Technology Services Gmbh |
Stoffe für selbstorganisierte Träger zur kontrollierten Freisetzung eines Wirkstoffs
|
EA028875B1
(ru)
*
|
2009-10-15 |
2018-01-31 |
Янссен Вэксинс Энд Превеншн Б.В. |
Способ очистки аденовирусных частиц из клеточной суспензии
|
ES2666559T3
(es)
|
2009-12-01 |
2018-05-07 |
Translate Bio, Inc. |
Entrega del mrna para la aumentación de proteínas y enzimas en enfermedades genéticas humanas
|
PT3112467T
(pt)
|
2009-12-07 |
2018-04-16 |
Univ Pennsylvania |
Preparações de arn compreendendo arn modificado purificado para a reprogramação de células
|
US20130017223A1
(en)
|
2009-12-18 |
2013-01-17 |
The University Of British Columbia |
Methods and compositions for delivery of nucleic acids
|
EP2516010A2
(en)
|
2009-12-23 |
2012-10-31 |
Novartis AG |
Lipids, lipid compositions, and methods of using them
|
US9315802B2
(en)
|
2009-12-30 |
2016-04-19 |
Quest Diagnostics Investments Incorporated |
RNA isolation from soluble urine fractions
|
CA2799091A1
(en)
|
2010-05-12 |
2011-11-17 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods of use thereof
|
EP4481047A2
(en)
|
2010-06-03 |
2024-12-25 |
Alnylam Pharmaceuticals, Inc. |
Biodegradable lipids for the delivery of active agents
|
CN101863544B
(zh)
|
2010-06-29 |
2011-09-28 |
湖南科技大学 |
一种氰尿酸基重金属螯合絮凝剂及其制备方法
|
US9006417B2
(en)
|
2010-06-30 |
2015-04-14 |
Protiva Biotherapeutics, Inc. |
Non-liposomal systems for nucleic acid delivery
|
WO2012016184A2
(en)
|
2010-07-30 |
2012-02-02 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for delivery of active agents
|
CA2807552A1
(en)
|
2010-08-06 |
2012-02-09 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
WO2012019630A1
(en)
|
2010-08-13 |
2012-02-16 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded protein
|
EP2609135A4
(en)
|
2010-08-26 |
2015-05-20 |
Massachusetts Inst Technology |
POLY (BETA AMINO ALCOHOLS), THEIR PREPARATION AND USES THEREOF
|
WO2012026493A1
(ja)
|
2010-08-26 |
2012-03-01 |
アイシン精機株式会社 |
酵素結晶固定化電極及び酵素結晶固定化電極の製造方法、並びに酵素結晶固定化電極を備えるバイオ電池及びバイオセンサー
|
US20130337579A1
(en)
|
2010-09-03 |
2013-12-19 |
University Of Maryland, College Park |
Methods for Determining Protein Ligand Binding
|
TWI441591B
(zh)
*
|
2010-09-07 |
2014-06-21 |
Univ Nat Central |
使植物表現後天性高溫逆境耐受性狀的方法及其應用
|
PT3590949T
(pt)
|
2010-10-01 |
2022-08-02 |
Modernatx Inc |
Ácidos ribonucleicos contendo n1-metilpseudouracilos e suas utilizações
|
US8853377B2
(en)
|
2010-11-30 |
2014-10-07 |
Shire Human Genetic Therapies, Inc. |
mRNA for use in treatment of human genetic diseases
|
WO2012077080A1
(en)
*
|
2010-12-10 |
2012-06-14 |
Tracy Thompson |
Compositions for separation methods
|
US9238716B2
(en)
|
2011-03-28 |
2016-01-19 |
Massachusetts Institute Of Technology |
Conjugated lipomers and uses thereof
|
WO2012133737A1
(ja)
|
2011-03-31 |
2012-10-04 |
公益財団法人地球環境産業技術研究機構 |
架橋性アミン化合物、該化合物を用いた高分子膜及びその製造方法
|
JP2014511687A
(ja)
|
2011-03-31 |
2014-05-19 |
モデルナ セラピューティクス インコーポレイテッド |
工学操作された核酸の送達および製剤
|
EP2705152B1
(en)
|
2011-05-04 |
2017-10-25 |
The Broad Institute, Inc. |
Multiplexed genetic reporter assays and compositions
|
BR112013029490A2
(pt)
|
2011-05-17 |
2019-09-24 |
Moderna Therapeutics Inc |
ácidos nucleicos projetados e métodos de uso dos mesmos para vertebrados não humanos
|
EP2532649B1
(en)
|
2011-06-07 |
2015-04-08 |
Incella GmbH |
Amino lipids, their synthesis and uses thereof
|
ES2795110T3
(es)
|
2011-06-08 |
2020-11-20 |
Translate Bio Inc |
Lípidos escindibles
|
DK3586861T3
(da)
|
2011-06-08 |
2022-04-25 |
Translate Bio Inc |
Lipidnanopartikelsammensætninger og fremgangsmåder til mrna-indgivelse
|
WO2013003475A1
(en)
|
2011-06-27 |
2013-01-03 |
Cellscript, Inc. |
Inhibition of innate immune response
|
WO2013003767A2
(en)
*
|
2011-06-30 |
2013-01-03 |
Sigma-Aldrich Co. Llc |
Cells deficient in cmp-n-acetylneuraminic acid hydroxylase and/or glycoprotein alpha-1,3-galactosyltransferase
|
WO2013039857A1
(en)
|
2011-09-12 |
2013-03-21 |
modeRNA Therapeutics |
Engineered nucleic acids and methods of use thereof
|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
EP3384938A1
(en)
|
2011-09-12 |
2018-10-10 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
KR20190099538A
(ko)
|
2011-10-03 |
2019-08-27 |
모더나 세라퓨틱스, 인코포레이티드 |
변형된 뉴클레오사이드, 뉴클레오타이드, 및 핵산, 및 이들의 용도
|
RU2014117690A
(ru)
|
2011-10-05 |
2015-11-10 |
Протива Байотерапьютикс Инк. |
Композиции и способы для сайленсинга альдегид-дегидрогеназы
|
EA032088B1
(ru)
|
2011-10-27 |
2019-04-30 |
Массачусетс Инститьют Оф Текнолоджи |
Аминокислотные производные, функционализованные на n-конце, способные образовывать микросферы, инкапсулирующие лекарственное средство
|
US20140343129A1
(en)
|
2011-12-14 |
2014-11-20 |
Moderna Therapeutics, Inc. |
Modified nucleic acids, and acute care uses thereof
|
US20140378538A1
(en)
|
2011-12-14 |
2014-12-25 |
Moderma Therapeutics, Inc. |
Methods of responding to a biothreat
|
SG11201402666WA
(en)
|
2011-12-16 |
2014-10-30 |
Moderna Therapeutics Inc |
Modified nucleoside, nucleotide, and nucleic acid compositions
|
CA2859691A1
(en)
|
2011-12-21 |
2013-06-27 |
Moderna Therapeutics, Inc. |
Methods of increasing the viability or longevity of an organ or organ explant
|
US20140371302A1
(en)
|
2011-12-29 |
2014-12-18 |
Modema Therapeutics, Inc. |
Modified mrnas encoding cell-penetrating polypeptides
|
PL3421601T3
(pl)
|
2011-12-30 |
2020-06-01 |
Cellscript, Llc |
Wytwarzanie i stosowanie zsyntetyzowanego in vitro ssRNA do wprowadzania do ssaczych komórek w celu indukcji efektu biologicznego lub biochemicznego
|
ES2898912T3
(es)
|
2012-02-24 |
2022-03-09 |
Arbutus Biopharma Corp |
Lípidos catiónicos de trialquilo y métodos para su uso
|
JP6211054B2
(ja)
|
2012-03-29 |
2017-10-11 |
シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド |
脂質誘導される中性ナノ粒子
|
US9546128B2
(en)
|
2012-03-29 |
2017-01-17 |
Shire Human Genetic Therapies, Inc. |
Ionizable cationic lipids
|
CN104411338A
(zh)
|
2012-04-02 |
2015-03-11 |
现代治疗公司 |
用于产生与人类疾病相关的生物制剂和蛋白质的修饰多核苷酸
|
US9283287B2
(en)
|
2012-04-02 |
2016-03-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
US9878056B2
(en)
|
2012-04-02 |
2018-01-30 |
Modernatx, Inc. |
Modified polynucleotides for the production of cosmetic proteins and peptides
|
US20140275229A1
(en)
|
2012-04-02 |
2014-09-18 |
Moderna Therapeutics, Inc. |
Modified polynucleotides encoding udp glucuronosyltransferase 1 family, polypeptide a1
|
EP2847329A4
(en)
|
2012-04-02 |
2016-08-10 |
Moderna Therapeutics Inc |
MODIFIED POLYNUCLEOTIDES FOR THE PREPARATION OF CYTOPLASMA AND CYTOSCELETTE PROTEINS
|
US9572897B2
(en)
|
2012-04-02 |
2017-02-21 |
Modernatx, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
US20150050354A1
(en)
|
2012-04-02 |
2015-02-19 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the treatment of otic diseases and conditions
|
EP2859102A4
(en)
|
2012-06-08 |
2016-05-11 |
Shire Human Genetic Therapies |
NUCLEASE RESISTANT POLYNUCLEOTIDES AND USES THEREOF
|
EP3884949A1
(en)
|
2012-06-08 |
2021-09-29 |
Translate Bio, Inc. |
Pulmonary delivery of mrna to non-lung target cells
|
EP2674167A1
(en)
|
2012-06-14 |
2013-12-18 |
PLS-Design GmbH |
Controlled activation of complement components for use as endogenous adjuvant
|
CA2884870C
(en)
|
2012-08-13 |
2022-03-29 |
Massachusetts Institute Of Technology |
Amine-containing lipidoids and uses thereof
|
US20140093952A1
(en)
|
2012-10-02 |
2014-04-03 |
David Serway |
Bioreactor Tangential Flow Perfusion Filter System
|
MX364644B
(es)
*
|
2012-11-21 |
2019-05-03 |
Serum Inst India Ltd |
Produccion de altos rendimientos de polisacaridos bacteriales.
|
RS63237B1
(sr)
|
2012-11-26 |
2022-06-30 |
Modernatx Inc |
Terminalno modifikovana rnk
|
ES2968649T3
(es)
|
2012-12-07 |
2024-05-13 |
Translate Bio Inc |
Nanopartículas lipídicas para la administración de ARNm en los pulmones
|
US20150315541A1
(en)
|
2012-12-13 |
2015-11-05 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for altering cell phenotype
|
EP2931319B1
(en)
|
2012-12-13 |
2019-08-21 |
ModernaTX, Inc. |
Modified nucleic acid molecules and uses thereof
|
CN110106229B
(zh)
*
|
2013-01-03 |
2023-03-28 |
外来体诊断公司 |
用于分离微囊泡的方法
|
JP2016504050A
(ja)
|
2013-01-17 |
2016-02-12 |
モデルナ セラピューティクス インコーポレイテッドModerna Therapeutics,Inc. |
細胞表現型の改変のためのシグナルセンサーポリヌクレオチド
|
US20160022774A1
(en)
|
2013-03-12 |
2016-01-28 |
Moderna Therapeutics, Inc. |
Diagnosis and treatment of fibrosis
|
US20160024181A1
(en)
|
2013-03-13 |
2016-01-28 |
Moderna Therapeutics, Inc. |
Long-lived polynucleotide molecules
|
JP6399560B2
(ja)
|
2013-03-14 |
2018-10-03 |
トランスレイト バイオ, インコーポレイテッド |
mRNAによってコードされる抗体を送達するための方法及び組成物
|
EP3431592A1
(en)
|
2013-03-14 |
2019-01-23 |
Translate Bio, Inc. |
Mrna therapeutic compositions and use to treat diseases and disorders
|
BR112015022507A2
(pt)
|
2013-03-14 |
2017-10-24 |
Shire Human Genetic Therapies |
ácidos ribonucleicos com nucleotídeos 4'-tio-modificados, composição compreendendo o mesmo e usos relacionados
|
EP2971098B1
(en)
|
2013-03-14 |
2018-11-21 |
Translate Bio, Inc. |
Quantitative assessment for cap efficiency of messenger rna
|
NZ751462A
(en)
|
2013-03-14 |
2021-07-30 |
Shire Human Genetic Therapies |
Cftr mrna compositions and related methods and uses
|
WO2014152211A1
(en)
|
2013-03-14 |
2014-09-25 |
Moderna Therapeutics, Inc. |
Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions
|
EP2970955B1
(en)
*
|
2013-03-14 |
2018-11-14 |
Translate Bio, Inc. |
Methods for purification of messenger rna
|
MX2015011944A
(es)
|
2013-03-14 |
2015-12-01 |
Shire Human Genetic Therapies |
Evaluacion cuantitativa para la eficacia de los casquetes de arn mensajero.
|
EP2971165A4
(en)
|
2013-03-15 |
2016-11-23 |
Moderna Therapeutics Inc |
DISSOLUTION OF DNA FRAGMENTS IN MRNA MANUFACTURING METHODS
|
EP2983804A4
(en)
|
2013-03-15 |
2017-03-01 |
Moderna Therapeutics, Inc. |
Ion exchange purification of mrna
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
EP3578663A1
(en)
*
|
2013-03-15 |
2019-12-11 |
ModernaTX, Inc. |
Manufacturing methods for production of rna transcripts
|
EP4279610A3
(en)
|
2013-03-15 |
2024-01-03 |
ModernaTX, Inc. |
Ribonucleic acid purification
|
WO2014144711A1
(en)
|
2013-03-15 |
2014-09-18 |
Moderna Therapeutics, Inc. |
Analysis of mrna heterogeneity and stability
|
WO2014144039A1
(en)
|
2013-03-15 |
2014-09-18 |
Moderna Therapeutics, Inc. |
Characterization of mrna molecules
|
PT2970948T
(pt)
*
|
2013-03-15 |
2019-03-20 |
Glaxosmithkline Biologicals Sa |
Métodos de purificação de arn
|
LT2972360T
(lt)
|
2013-03-15 |
2018-09-10 |
Translate Bio, Inc. |
Sinergistinis nukleorūgščių pristatymo padidinimas sumaišytų kompozicijų pagalba
|
WO2014179562A1
(en)
|
2013-05-01 |
2014-11-06 |
Massachusetts Institute Of Technology |
1,3,5-triazinane-2,4,6-trione derivatives and uses thereof
|
WO2014210356A1
(en)
|
2013-06-26 |
2014-12-31 |
Massachusetts Institute Of Technology |
Multi-tailed lipids and uses thereof
|
CA2917348A1
(en)
|
2013-07-11 |
2015-01-15 |
Moderna Therapeutics, Inc. |
Compositions comprising synthetic polynucleotides encoding crispr related proteins and synthetic sgrnas and methods of use
|
JP6620093B2
(ja)
|
2013-07-23 |
2019-12-11 |
アービュートゥス バイオファーマ コーポレイションArbutus Biopharma Corporation |
メッセンジャーrnaを送達するための組成物及び方法
|
EP3041934A1
(en)
|
2013-09-03 |
2016-07-13 |
Moderna Therapeutics, Inc. |
Chimeric polynucleotides
|
WO2015034925A1
(en)
|
2013-09-03 |
2015-03-12 |
Moderna Therapeutics, Inc. |
Circular polynucleotides
|
EP3052106A4
(en)
|
2013-09-30 |
2017-07-19 |
ModernaTX, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
EP3052479A4
(en)
|
2013-10-02 |
2017-10-25 |
Moderna Therapeutics, Inc. |
Polynucleotide molecules and uses thereof
|
US10385088B2
(en)
|
2013-10-02 |
2019-08-20 |
Modernatx, Inc. |
Polynucleotide molecules and uses thereof
|
EP3058082A4
(en)
|
2013-10-18 |
2017-04-26 |
ModernaTX, Inc. |
Compositions and methods for tolerizing cellular systems
|
EP3574923A1
(en)
|
2013-10-22 |
2019-12-04 |
Translate Bio, Inc. |
Mrna therapy for phenylketonuria
|
AU2014340092B2
(en)
|
2013-10-22 |
2019-09-19 |
Translate Bio, Inc. |
mRNA therapy for Argininosuccinate Synthetase Deficiency
|
EP4036241A1
(en)
|
2013-10-22 |
2022-08-03 |
Translate Bio, Inc. |
Cns delivery of mrna and uses thereof
|
US20170173128A1
(en)
|
2013-12-06 |
2017-06-22 |
Moderna TX, Inc. |
Targeted adaptive vaccines
|
EP2918275B1
(en)
|
2013-12-13 |
2016-05-18 |
Moderna Therapeutics, Inc. |
Alternative nucleic acid molecules and uses thereof
|
US20170002060A1
(en)
|
2014-01-08 |
2017-01-05 |
Moderna Therapeutics, Inc. |
Polynucleotides for the in vivo production of antibodies
|
EP4501318A2
(en)
|
2014-04-23 |
2025-02-05 |
ModernaTX, Inc. |
Nucleic acid vaccines
|
EP3636742A1
(en)
|
2014-04-25 |
2020-04-15 |
Translate Bio, Inc. |
Methods for purification of messenger rna
|
JP6347163B2
(ja)
|
2014-07-10 |
2018-06-27 |
株式会社リコー |
定着装置及び画像形成装置
|
WO2016054421A1
(en)
|
2014-10-02 |
2016-04-07 |
Protiva Biotherapeutics, Inc |
Compositions and methods for silencing hepatitis b virus gene expression
|
WO2016071857A1
(en)
|
2014-11-07 |
2016-05-12 |
Protiva Biotherapeutics, Inc. |
Compositions and methods for silencing ebola virus expression
|
EP3041948B1
(en)
|
2014-11-10 |
2019-01-09 |
Modernatx, Inc. |
Alternative nucleic acid molecules containing reduced uracil content and uses thereof
|
EP3218508A4
(en)
|
2014-11-10 |
2018-04-18 |
Modernatx, Inc. |
Multiparametric nucleic acid optimization
|
WO2016118724A1
(en)
|
2015-01-21 |
2016-07-28 |
Moderna Therapeutics, Inc. |
Lipid nanoparticle compositions
|
EP3247398A4
(en)
|
2015-01-23 |
2018-09-26 |
Moderna Therapeutics, Inc. |
Lipid nanoparticle compositions
|
CA2979998A1
(en)
|
2015-03-20 |
2016-09-29 |
Protiva Biotherapeutics, Inc. |
Compositions and methods for treating hypertriglyceridemia
|
WO2016164762A1
(en)
|
2015-04-08 |
2016-10-13 |
Moderna Therapeutics, Inc. |
Polynucleotides encoding low density lipoprotein receptor egf-a and intracellular domain mutants and methods of using the same
|
WO2016183366A2
(en)
|
2015-05-12 |
2016-11-17 |
Protiva Biotherapeutics, Inc. |
Compositions and methods for silencing expression of hepatitis d virus rna
|
DE202016009003U1
(de)
*
|
2015-05-29 |
2021-05-28 |
Curevac Real Estate Gmbh |
Zusammensetzung umfassend in vitro transkribierte RNA erhältlich durch ein Verfahren zur Herstellung und Reinigung von RNA mit mindestens einem Schritt mit einer tangentialen Flussfiltration
|
WO2016197132A1
(en)
|
2015-06-04 |
2016-12-08 |
Protiva Biotherapeutics Inc. |
Treating hepatitis b virus infection using crispr
|
US10626393B2
(en)
|
2015-06-04 |
2020-04-21 |
Arbutus Biopharma Corporation |
Delivering CRISPR therapeutics with lipid nanoparticles
|
EP3307305A4
(en)
|
2015-06-10 |
2019-05-22 |
Modernatx, Inc. |
TARGETED ADAPTIVE VACCINES
|
WO2017149139A1
(en)
|
2016-03-03 |
2017-09-08 |
Curevac Ag |
Rna analysis by total hydrolysis
|
CA3054321A1
(en)
|
2017-02-27 |
2018-08-30 |
Translate Bio, Inc. |
Methods for purification of messenger rna
|
MX2021009169A
(es)
|
2019-02-11 |
2021-10-13 |
Ethris Gmbh |
Purificacion de arnm por filtracion de flujo tangencial.
|