|
SI1957539T1
(sl)
|
2005-12-08 |
2013-05-31 |
Medarex, Inc. |
Humana monoklonska protitelesa proti protein tirozin kinazi 7 (PTK7) in njihova uporaba
|
|
AR072999A1
(es)
|
2008-08-11 |
2010-10-06 |
Medarex Inc |
Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
|
|
TWI807362B
(zh)
|
2010-11-30 |
2023-07-01 |
日商中外製藥股份有限公司 |
細胞傷害誘導治療劑
|
|
US8440797B2
(en)
|
2010-12-06 |
2013-05-14 |
Dainippon Sumitomo Pharma Co., Ltd. |
Human monoclonal antibody
|
|
CN103249833B
(zh)
*
|
2010-12-06 |
2016-06-29 |
大日本住友制药株式会社 |
人单克隆抗体
|
|
JP6093712B2
(ja)
|
2010-12-22 |
2017-03-08 |
ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー |
インターロイキン２のスーパーアゴニストおよびアンタゴニスト
|
|
PT3357511T
(pt)
*
|
2011-06-30 |
2020-07-23 |
Genzyme Corp |
Inibidores da ativação de células t
|
|
HUE052198T2
(hu)
|
2011-07-21 |
2021-04-28 |
Sumitomo Dainippon Pharma Oncology Inc |
Heterociklusos protein kináz inhibitorok
|
|
UY34887A
(es)
*
|
2012-07-02 |
2013-12-31 |
Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware |
Optimización de anticuerpos que se fijan al gen de activación de linfocitos 3 (lag-3) y sus usos
|
|
EP2970909A4
(en)
|
2013-03-15 |
2017-02-15 |
The University of Chicago |
Methods and compositions related to t-cell activity
|
|
PL2970464T3
(pl)
*
|
2013-03-15 |
2020-10-05 |
Glaxosmithkline Intellectual Property Development Limited |
Wiążące białka anty-lag-3
|
|
TWI654206B
(zh)
|
2013-03-16 |
2019-03-21 |
諾華公司 |
使用人類化抗－ｃｄ１９嵌合抗原受體治療癌症
|
|
MX2015015037A
(es)
|
2013-05-02 |
2016-07-08 |
Anaptysbio Inc |
Anticuerpos dirigidos contra la proteina muerte programada-1 (pd-1).
|
|
EA036591B1
(ru)
|
2013-06-25 |
2020-11-26 |
Вэксинекс, Инк. |
Способ ингибирования, замедления или уменьшения роста раковой опухоли у субъекта
|
|
CN105682683A
(zh)
|
2013-08-02 |
2016-06-15 |
阿杜罗生物科技控股有限公司 |
结合cd27激动剂以及免疫检查点抑制以用于免疫刺激
|
|
EP3995507B1
(en)
|
2013-08-08 |
2023-10-04 |
Cytune Pharma |
Il-15 and il-15ralpha sushi domain based on modulokines
|
|
LT3030262T
(lt)
|
2013-08-08 |
2020-03-10 |
Cytune Pharma |
Kombinuota farmacinė kompozicija
|
|
FI3508502T3
(fi)
*
|
2013-09-20 |
2023-06-06 |
Bristol Myers Squibb Co |
Anti-lag-3-vasta-aineiden ja anti-pd-1-vasta-aineiden yhdistelmä kasvainten hoitamiseksi
|
|
US10781242B2
(en)
|
2013-09-24 |
2020-09-22 |
Medicenna Therapeutics Inc. |
Interleukin-2 fusion proteins and uses thereof
|
|
US10570204B2
(en)
|
2013-09-26 |
2020-02-25 |
The Medical College Of Wisconsin, Inc. |
Methods for treating hematologic cancers
|
|
WO2015066413A1
(en)
|
2013-11-01 |
2015-05-07 |
Novartis Ag |
Oxazolidinone hydroxamic acid compounds for the treatment of bacterial infections
|
|
EP3083686B2
(en)
*
|
2013-12-17 |
2023-03-22 |
F. Hoffmann-La Roche AG |
Methods of treating cancers using pd-1 axis binding antagonists and taxanes
|
|
EP3083690A1
(en)
*
|
2013-12-17 |
2016-10-26 |
F.Hoffmann-La Roche Ag |
Methods of treating cancer using pd-1 axis binding antagonists and an anti-cd20 antibody
|
|
GB201322626D0
(en)
|
2013-12-19 |
2014-02-05 |
Immutep S A |
Combined preparations for the treatment of cancer
|
|
JP6779785B2
(ja)
|
2013-12-19 |
2020-11-04 |
ノバルティス アーゲー |
ヒトメソテリンキメラ抗原受容体およびその使用
|
|
CN106029663B
(zh)
|
2013-12-24 |
2018-06-01 |
百时美施贵宝公司 |
作为抗癌剂的新颖三环化合物
|
|
JO3517B1
(ar)
|
2014-01-17 |
2020-07-05 |
Novartis Ag |
ان-ازاسبيرو الكان حلقي كبديل مركبات اريل-ان مغايرة وتركيبات لتثبيط نشاط shp2
|
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
|
WO2015116539A1
(en)
*
|
2014-01-28 |
2015-08-06 |
Bristol-Myers Squibb Company |
Anti-lag-3 antibodies to treat hematological malignancies
|
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
|
CN106687125B
(zh)
|
2014-03-12 |
2021-12-14 |
耶达研究与开发有限公司 |
降低系统性调节性t细胞水平或活性来治疗cns疾病和损伤
|
|
US10618963B2
(en)
|
2014-03-12 |
2020-04-14 |
Yeda Research And Development Co. Ltd |
Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS
|
|
US10519237B2
(en)
|
2014-03-12 |
2019-12-31 |
Yeda Research And Development Co. Ltd |
Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS
|
|
US9394365B1
(en)
|
2014-03-12 |
2016-07-19 |
Yeda Research And Development Co., Ltd |
Reducing systemic regulatory T cell levels or activity for treatment of alzheimer's disease
|
|
WO2015138920A1
(en)
*
|
2014-03-14 |
2015-09-17 |
Novartis Ag |
Antibody molecules to lag-3 and uses thereof
|
|
WO2015142675A2
(en)
|
2014-03-15 |
2015-09-24 |
Novartis Ag |
Treatment of cancer using chimeric antigen receptor
|
|
PL3122745T3
(pl)
|
2014-03-24 |
2019-08-30 |
Novartis Ag |
Monobaktamowe związki organiczne do leczenia zakażeń bakteryjnych
|
|
IL247715B
(en)
|
2014-04-07 |
2022-07-01 |
Chugai Pharmaceutical Co Ltd |
Immunoactivating antigen-binding molecule
|
|
WO2015157252A1
(en)
|
2014-04-07 |
2015-10-15 |
BROGDON, Jennifer |
Treatment of cancer using anti-cd19 chimeric antigen receptor
|
|
CN106659757B
(zh)
|
2014-04-24 |
2022-01-28 |
利兰斯坦福初级大学董事会 |
白介素2的超级激动剂、部分激动剂和拮抗剂
|
|
AU2015260230A1
(en)
|
2014-05-13 |
2016-11-17 |
Chugai Seiyaku Kabushiki Kaisha |
T cell-redirected antigen-binding molecule for cells having immunosuppression function
|
|
AU2015261536B2
(en)
*
|
2014-05-16 |
2020-05-07 |
Ablynx Nv |
Improved immunoglobulin variable domains
|
|
NZ764826A
(en)
|
2014-05-28 |
2024-09-27 |
Memorial Sloan Kettering Cancer Center |
Anti-gitr antibodies and methods of use thereof
|
|
PT3151921T
(pt)
|
2014-06-06 |
2019-11-21 |
Bristol Myers Squibb Co |
Anticorpos contra recetor do fator de necrose tumoral induzido por glicocorticoide e utilizações dos mesmos
|
|
WO2015188085A1
(en)
|
2014-06-06 |
2015-12-10 |
Flexus Biosciences, Inc. |
Immunoregulatory agents
|
|
TWI693232B
(zh)
*
|
2014-06-26 |
2020-05-11 |
美商宏觀基因股份有限公司 |
與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
|
|
US11542488B2
(en)
|
2014-07-21 |
2023-01-03 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
EP3722316A1
(en)
|
2014-07-21 |
2020-10-14 |
Novartis AG |
Treatment of cancer using a cd33 chimeric antigen receptor
|
|
JP2017528433A
(ja)
|
2014-07-21 |
2017-09-28 |
ノバルティス アーゲー |
低い免疫増強用量のｍＴＯＲ阻害剤とＣＡＲの組み合わせ
|
|
KR102612313B1
(ko)
|
2014-07-21 |
2023-12-12 |
노파르티스 아게 |
인간화 항-bcma 키메라 항원 수용체를 사용한 암의 치료
|
|
US20170209492A1
(en)
|
2014-07-31 |
2017-07-27 |
Novartis Ag |
Subset-optimized chimeric antigen receptor-containing t-cells
|
|
US10160726B2
(en)
|
2014-08-06 |
2018-12-25 |
Novartis Ag |
Quinolone derivatives as antibacterials
|
|
US20170224777A1
(en)
|
2014-08-12 |
2017-08-10 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with il-2, a therapeutic antibody, and a cancer vaccine
|
|
AU2015301753B2
(en)
|
2014-08-12 |
2021-04-08 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with IL-2 and integrin-binding-Fc-fusion protein
|
|
AU2015301460B2
(en)
|
2014-08-14 |
2021-04-08 |
Novartis Ag |
Treatment of cancer using GFR alpha-4 chimeric antigen receptor
|
|
JO3663B1
(ar)
*
|
2014-08-19 |
2020-08-27 |
Merck Sharp & Dohme |
الأجسام المضادة لمضاد lag3 وأجزاء ربط الأنتيجين
|
|
JP7084138B2
(ja)
|
2014-08-19 |
2022-06-14 |
ノバルティス アーゲー |
癌処置に使用するための抗ｃｄ１２３キメラ抗原受容体（ｃａｒ）
|
|
JP6681905B2
(ja)
|
2014-09-13 |
2020-04-15 |
ノバルティス アーゲー |
Ａｌｋ阻害剤の併用療法
|
|
PL3194443T3
(pl)
|
2014-09-17 |
2022-01-31 |
Novartis Ag |
Nakierowywanie komórek cytotoksycznych za pośrednictwem receptorów chimerycznych do immunoterapii adoptywnej
|
|
EP3662903A3
(en)
|
2014-10-03 |
2020-10-14 |
Novartis AG |
Combination therapies
|
|
EP3204777B1
(en)
|
2014-10-08 |
2024-06-12 |
Novartis AG |
Biomarkers predictive of therapeutic responsiveness to chimeric antigen receptor therapy and uses thereof
|
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
|
CA2964155A1
(en)
|
2014-10-10 |
2016-04-14 |
Idera Pharmaceuticals, Inc. |
Treatment of cancer using tlr9 agonist with checkpoint inhibitors
|
|
CR20170143A
(es)
|
2014-10-14 |
2017-06-19 |
Dana Farber Cancer Inst Inc |
Moléculas de anticuerpo que se unen a pd-l1 y usos de las mismas
|
|
UY36390A
(es)
|
2014-11-05 |
2016-06-01 |
Flexus Biosciences Inc |
Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido), sus métodos de síntesis y composiciones farmacéuticas que los contienen
|
|
EA201790806A1
(ru)
|
2014-11-05 |
2017-11-30 |
Флексус Байосайенсиз, Инк. |
Иммунорегулирующие средства
|
|
UY36391A
(es)
|
2014-11-05 |
2016-06-01 |
Flexus Biosciences Inc |
Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido1), sus métodos de síntesis y composiciones farmacèuticas que las contienen
|
|
CN107250157B
(zh)
|
2014-11-21 |
2021-06-29 |
百时美施贵宝公司 |
包含修饰的重链恒定区的抗体
|
|
ES2807182T3
(es)
|
2014-11-21 |
2021-02-22 |
Bristol Myers Squibb Co |
Anticuerpos frente a CD73 y sus usos
|
|
WO2016090034A2
(en)
|
2014-12-03 |
2016-06-09 |
Novartis Ag |
Methods for b cell preconditioning in car therapy
|
|
US9827308B2
(en)
|
2014-12-10 |
2017-11-28 |
Wisconsin Alumni Research Foundation |
Mini-intronic plasmid DNA vaccines in combination with LAG3 blockade
|
|
ME03546B
(me)
|
2014-12-16 |
2020-07-20 |
Novartis Ag |
Jedinjenja izoksazol hidroksamske kiseline kао inhibiтori lpxc
|
|
US20170340733A1
(en)
|
2014-12-19 |
2017-11-30 |
Novartis Ag |
Combination therapies
|
|
AR103232A1
(es)
|
2014-12-22 |
2017-04-26 |
Bristol Myers Squibb Co |
ANTAGONISTAS DE TGFbR
|
|
TN2017000267A1
(en)
|
2014-12-23 |
2018-10-19 |
Bristol Myers Squibb Co |
Antibodies to tigit
|
|
GB201500374D0
(en)
|
2015-01-09 |
2015-02-25 |
Immutep S A |
Combined preparations for the treatment of cancer
|
|
WO2016126608A1
(en)
|
2015-02-02 |
2016-08-11 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
|
MA41463A
(fr)
*
|
2015-02-03 |
2017-12-12 |
Anaptysbio Inc |
Anticorps dirigés contre le gène d'activation 3 des lymphocytes (lag-3)
|
|
US10983128B2
(en)
|
2015-02-05 |
2021-04-20 |
Bristol-Myers Squibb Company |
CXCL11 and SMICA as predictive biomarkers for efficacy of anti-CTLA4 immunotherapy
|
|
WO2016140884A1
(en)
|
2015-03-02 |
2016-09-09 |
Rigel Pharmaceuticals, Inc. |
TGF-β INHIBITORS
|
|
US10449211B2
(en)
|
2015-03-10 |
2019-10-22 |
Aduro Biotech, Inc. |
Compositions and methods for activating “stimulator of interferon gene”—dependent signalling
|
|
US20180133327A1
(en)
|
2015-03-16 |
2018-05-17 |
Amal Therapeutics Sa |
Cell Penetrating Peptides and Complexes Comprising the Same
|
|
AU2016243937A1
(en)
|
2015-04-03 |
2017-11-23 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase for the treatment of cancer
|
|
WO2016164580A1
(en)
|
2015-04-07 |
2016-10-13 |
Novartis Ag |
Combination of chimeric antigen receptor therapy and amino pyrimidine derivatives
|
|
TW201642897A
(zh)
|
2015-04-08 |
2016-12-16 |
Ｆ 星生物科技有限公司 |
Ｈｅｒ２結合劑治療
|
|
JP6961490B2
(ja)
|
2015-04-08 |
2021-11-05 |
ノバルティス アーゲー |
Ｃｄ２０療法、ｃｄ２２療法、およびｃｄ１９キメラ抗原受容体（ｃａｒ）発現細胞との併用療法
|
|
PT3283527T
(pt)
|
2015-04-13 |
2021-03-03 |
Five Prime Therapeutics Inc |
Terapêutica de combinação para o cancro
|
|
CN107743401B
(zh)
|
2015-04-17 |
2021-08-24 |
百时美施贵宝公司 |
包含抗pd-1抗体和另外的抗体的组合的组合物
|
|
EP4234685A3
(en)
|
2015-04-17 |
2023-09-06 |
Novartis AG |
Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
|
|
US12128069B2
(en)
|
2015-04-23 |
2024-10-29 |
The Trustees Of The University Of Pennsylvania |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
EP3563684A1
(en)
|
2015-05-06 |
2019-11-06 |
Snipr Technologies Limited |
Altering microbial populations & modifying microbiota
|
|
EP3294736B1
(en)
|
2015-05-11 |
2020-07-22 |
Bristol-Myers Squibb Company |
Tricyclic compounds as anticancer agents
|
|
US9725449B2
(en)
|
2015-05-12 |
2017-08-08 |
Bristol-Myers Squibb Company |
Tricyclic compounds as anticancer agents
|
|
EP3307740B1
(en)
|
2015-05-12 |
2019-12-18 |
Bristol-Myers Squibb Company |
5h-pyrido[3,2-b]indole compounds as anticancer agents
|
|
CN111234027A
(zh)
|
2015-05-21 |
2020-06-05 |
哈普恩治疗公司 |
三特异性结合蛋白质及使用方法
|
|
PE20180672A1
(es)
|
2015-05-29 |
2018-04-19 |
Agenus Inc |
Anticuerpos anti-ctla-4 y metodos de uso de los mismos
|
|
FI3303396T3
(fi)
|
2015-05-29 |
2023-02-22 |
|
Vasta-aineita ox40:ää vastaan ja niiden käyttöjä
|
|
EA039293B1
(ru)
*
|
2015-06-05 |
2021-12-30 |
Мерк Шарп И Доум Корп. |
Антитела против lag3 и антигенсвязывающие фрагменты
|
|
TWI773646B
(zh)
*
|
2015-06-08 |
2022-08-11 |
美商宏觀基因股份有限公司 |
結合lag-3的分子和其使用方法
|
|
AU2016281717B2
(en)
|
2015-06-24 |
2022-07-28 |
Janssen Biotech, Inc. |
Immune modulation and treatment of solid tumors with antibodies that specifically bind CD38
|
|
US10479838B2
(en)
|
2015-06-29 |
2019-11-19 |
Bristol-Myers Squibb Company |
Antibodies to CD40 with enhanced agonist activity
|
|
WO2017011666A1
(en)
|
2015-07-14 |
2017-01-19 |
Bristol-Myers Squibb Company |
Method of treating cancer using immune checkpoint inhibitor
|
|
EP3943098A3
(en)
|
2015-07-16 |
2022-05-11 |
Biokine Therapeutics Ltd. |
Compositions and methods for treating cancer
|
|
WO2017015427A1
(en)
|
2015-07-21 |
2017-01-26 |
Novartis Ag |
Methods for improving the efficacy and expansion of immune cells
|
|
AR105444A1
(es)
*
|
2015-07-22 |
2017-10-04 |
Sorrento Therapeutics Inc |
Anticuerpos terapéuticos que se unen a la proteína codificada por el gen de activación de linfocitos 3 (lag3)
|
|
KR20180034548A
(ko)
|
2015-07-28 |
2018-04-04 |
브리스톨-마이어스 스큅 컴퍼니 |
Tgf 베타 수용체 길항제
|
|
ES2878188T3
(es)
|
2015-07-29 |
2021-11-18 |
Novartis Ag |
Terapias de combinación que comprenden moléculas de anticuerpos contra LAG-3
|
|
US20180207273A1
(en)
|
2015-07-29 |
2018-07-26 |
Novartis Ag |
Combination therapies comprising antibody molecules to tim-3
|
|
US20180222982A1
(en)
|
2015-07-29 |
2018-08-09 |
Novartis Ag |
Combination therapies comprising antibody molecules to pd-1
|
|
PL3328419T3
(pl)
|
2015-07-30 |
2021-12-27 |
Macrogenics, Inc. |
Cząsteczki wiążące pd-1 i sposoby ich zastosowania
|
|
EP3331919A1
(en)
|
2015-08-07 |
2018-06-13 |
GlaxoSmithKline Intellectual Property Development Limited |
Combination therapy comprising anti ctla-4 antibodies
|
|
CN108349976A
(zh)
|
2015-08-25 |
2018-07-31 |
百时美施贵宝公司 |
TGFβ受体拮抗剂
|
|
PE20181322A1
(es)
|
2015-09-01 |
2018-08-14 |
Agenus Inc |
Anticuerpo anti-pd1 y sus metodos de uso
|
|
CN117510633A
(zh)
|
2015-09-02 |
2024-02-06 |
伊缪泰普有限公司 |
抗lag-3抗体
|
|
JP6905163B2
(ja)
|
2015-09-03 |
2021-07-21 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア |
サイトカイン放出症候群を予測するバイオマーカー
|
|
WO2017055404A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies specific for pd1 and tim3
|
|
TWI756187B
(zh)
|
2015-10-09 |
2022-03-01 |
美商再生元醫藥公司 |
抗ｌａｇ３抗體及其用途
|
|
US10149887B2
(en)
|
2015-10-23 |
2018-12-11 |
Canbas Co., Ltd. |
Peptides and peptidomimetics in combination with t cell activating and/or checkpoint inhibiting agents for cancer treatment
|
|
MA43163A
(fr)
|
2015-11-02 |
2018-09-12 |
Five Prime Therapeutics Inc |
Polypeptides à domaine extracellulaire cd80 et leur utilisation dans le traitement du cancer
|
|
LT3370768T
(lt)
|
2015-11-03 |
2022-05-25 |
Janssen Biotech, Inc. |
Antikūnai, specifiškai surišantys pd-1, ir jų panaudojimas
|
|
CN108884159A
(zh)
|
2015-11-07 |
2018-11-23 |
茂体外尔公司 |
用于癌症治疗的包含肿瘤抑制基因治疗和免疫检查点阻断的组合物
|
|
JP6945456B2
(ja)
*
|
2015-11-13 |
2021-10-06 |
マクロジェニクス，インコーポレーテッド |
Ｌａｇ‐３結合分子及びその使用方法
|
|
EP3378488A4
(en)
|
2015-11-18 |
2019-10-30 |
Chugai Seiyaku Kabushiki Kaisha |
METHOD FOR ENHANCING THE HUMORAL IMMUNE RESPONSE
|
|
JP6931329B2
(ja)
|
2015-11-18 |
2021-09-01 |
中外製薬株式会社 |
免疫抑制機能を有する細胞に対するｔ細胞リダイレクト抗原結合分子を用いた併用療法
|
|
EP3377531A2
(en)
|
2015-11-18 |
2018-09-26 |
Merck Sharp & Dohme Corp. |
Pd1 and/or lag3 binders
|
|
SG11201803817PA
(en)
|
2015-11-19 |
2018-06-28 |
Bristol Myers Squibb Co |
Antibodies against glucocorticoid-induced tumor necrosis factor receptor (gitr) and uses thereof
|
|
EP3377533A2
(en)
*
|
2015-11-19 |
2018-09-26 |
Sutro Biopharma, Inc. |
Anti-lag3 antibodies, compositions comprising anti-lag3 antibodies and methods of making and using anti-lag3 antibodies
|
|
LT3376857T
(lt)
|
2015-11-20 |
2021-06-25 |
Regeneron Pharmaceuticals, Inc. |
Gyvūnai, ne žmonės, turintys humanizuotą limfocitų aktyvavimo geną
|
|
EP3380523A1
(en)
|
2015-11-23 |
2018-10-03 |
Five Prime Therapeutics, Inc. |
Fgfr2 inhibitors alone or in combination with immune stimulating agents in cancer treatment
|
|
TWI717432B
(zh)
|
2015-12-02 |
2021-02-01 |
美商艾吉納斯公司 |
抗體和使用彼之方法
|
|
MA44082A
(fr)
|
2015-12-14 |
2018-10-24 |
Macrogenics Inc |
Molécules bispécifiques présentant une immunoréactivité par rapport à pd-1 et à ctla-4 et leurs procédés d'utilisation
|
|
EP3390406A1
(en)
|
2015-12-15 |
2018-10-24 |
Bristol-Myers Squibb Company |
Cxcr4 receptor antagonists
|
|
CA3008244A1
(en)
|
2015-12-16 |
2017-06-22 |
Merck Sharp & Dohme Corp. |
Anti-lag3 antibodies and antigen-binding fragments
|
|
BR112018012138A2
(pt)
|
2015-12-17 |
2018-12-04 |
Novartis Ag |
moléculas de anticorpo para pd-1 e usos das mesmas
|
|
US10392442B2
(en)
|
2015-12-17 |
2019-08-27 |
Bristol-Myers Squibb Company |
Use of anti-PD-1 antibody in combination with anti-CD27 antibody in cancer treatment
|
|
US11433136B2
(en)
|
2015-12-18 |
2022-09-06 |
The General Hospital Corporation |
Polyacetal polymers, conjugates, particles and uses thereof
|
|
CN109069623A
(zh)
|
2015-12-18 |
2018-12-21 |
诺华股份有限公司 |
靶向CD32b的抗体及其使用方法
|
|
MA44140A
(fr)
|
2015-12-22 |
2021-05-19 |
Dana Farber Cancer Inst Inc |
Récepteur d'antigène chimérique (car) contre la mésothéline et anticorps contre l'inhibiteur de pd-l1 pour une utilisation combinée dans une thérapie anticancéreuse
|
|
US10889643B2
(en)
|
2016-01-11 |
2021-01-12 |
Universität Zürich |
Immune-stimulating humanized monoclonal antibodies against human interleukin-2, and fusion proteins thereof
|
|
US20200270265A1
(en)
|
2016-02-19 |
2020-08-27 |
Novartis Ag |
Tetracyclic pyridone compounds as antivirals
|
|
JP2019513347A
(ja)
|
2016-03-04 |
2019-05-30 |
ノバルティス アーゲー |
複数のキメラ抗原受容体（ｃａｒ）分子を発現する細胞およびその使用
|
|
MX2018010473A
(es)
|
2016-03-04 |
2018-09-28 |
Squibb Bristol Myers Co |
Terapia de combinacion con anticuerpos anti cumulo de diferenciacion 73 (cd73).
|
|
SG10201601719RA
(en)
*
|
2016-03-04 |
2017-10-30 |
Agency Science Tech & Res |
Anti-LAG-3 Antibodies
|
|
BR112018068461A2
(pt)
|
2016-03-15 |
2019-01-22 |
Mersana Therapeutics Inc |
conjugado, composição farmacêutica, métodos para preparação de um conjugado e para alívio de um sintoma de um câncer.
|
|
JP7189021B2
(ja)
|
2016-03-16 |
2022-12-13 |
アマル セラピューティクス エスエー |
医療において使用するための、免疫チェックポイントモジュレータと、細胞透過性ペプチド、カーゴ、及びｔｌｒペプチドアゴニストを含む複合体との組合せ
|
|
EP3433257B1
(en)
|
2016-03-24 |
2023-10-11 |
Novartis AG |
Alkynyl nucleoside analogs as inhibitors of human rhinovirus
|
|
EP3445391A1
(en)
|
2016-04-13 |
2019-02-27 |
Vivia Biotech S.L. |
Ex vivo bite-activated t cells
|
|
US20200377606A1
(en)
|
2016-04-18 |
2020-12-03 |
Celldex Therapeutics, Inc. |
Agonistic antibodies that bind human cd40 and uses thereof
|
|
WO2017192844A1
(en)
|
2016-05-04 |
2017-11-09 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
KR20190003686A
(ko)
|
2016-05-04 |
2019-01-09 |
브리스톨-마이어스 스큅 컴퍼니 |
인돌아민 2,3-디옥시게나제의 억제제 및 그의 사용 방법
|
|
CN109311816A
(zh)
|
2016-05-04 |
2019-02-05 |
百时美施贵宝公司 |
吲哚胺2,3-双加氧酶的抑制剂及其使用方法
|
|
WO2017192815A1
(en)
|
2016-05-04 |
2017-11-09 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
KR20190003685A
(ko)
|
2016-05-04 |
2019-01-09 |
브리스톨-마이어스 스큅 컴퍼니 |
인돌아민 2,3-디옥시게나제의 억제제 및 그의 사용 방법
|
|
CA3020649A1
(en)
*
|
2016-05-18 |
2017-11-23 |
Boehringer Ingelheim International Gmbh |
Anti pd-1 and anti-lag3 antibodies for cancer treatment
|
|
US11623958B2
(en)
|
2016-05-20 |
2023-04-11 |
Harpoon Therapeutics, Inc. |
Single chain variable fragment CD3 binding proteins
|
|
SG11201809669RA
(en)
|
2016-05-20 |
2018-11-29 |
Biohaven Pharm Holding Co Ltd |
Use of glutamate modulating agents with immunotherapies to treat cancer
|
|
US11090344B2
(en)
|
2016-05-27 |
2021-08-17 |
Dnatrix, Inc. |
Adenovirus and immunomodulator combination therapy
|
|
SG11201810951RA
(en)
|
2016-06-10 |
2019-01-30 |
Io Therapeutics Inc |
Receptor selective retinoid and rexinoid compounds and immune modulators for cancer immunotherapy
|
|
JP7185530B2
(ja)
|
2016-06-13 |
2022-12-07 |
トルク セラピューティクス， インコーポレイテッド |
免疫細胞機能を促進するための方法および組成物
|
|
EA036243B1
(ru)
|
2016-06-14 |
2020-10-16 |
Новартис Аг |
Кристаллическая форма (r)-4-(5-(циклопропилэтинил)изоксазол-3-ил)-n-гидрокси-2-метил-2-(метилсульфонил)бутанамида как антибактериальное средство
|
|
WO2017216685A1
(en)
|
2016-06-16 |
2017-12-21 |
Novartis Ag |
Pentacyclic pyridone compounds as antivirals
|
|
WO2017216686A1
(en)
|
2016-06-16 |
2017-12-21 |
Novartis Ag |
8,9-fused 2-oxo-6,7-dihydropyrido-isoquinoline compounds as antivirals
|
|
MX2018016344A
(es)
|
2016-06-20 |
2019-05-30 |
F Star Beta Ltd |
Miembros de union lag-3.
|
|
TW201803906A
(zh)
*
|
2016-06-20 |
2018-02-01 |
Ｆ星德爾塔有限公司 |
結合物件(二)
|
|
JP7461741B2
(ja)
|
2016-06-20 |
2024-04-04 |
カイマブ・リミテッド |
抗ｐｄ－ｌ１およびｉｌ－２サイトカイン
|
|
MX2018015393A
(es)
*
|
2016-06-23 |
2019-04-29 |
Jiangsu Hengrui Medicine Co |
Anticuerpo lag-3, fragmento de union al antigeno del mismo y aplicacion farmaceutica del mismo.
|
|
CN109640999A
(zh)
|
2016-06-24 |
2019-04-16 |
无限药品股份有限公司 |
组合疗法
|
|
RU2758007C2
(ru)
|
2016-06-30 |
2021-10-25 |
Онкорус, Инк. |
Доставка терапевтических полипептидов посредством псевдотипированных онколитических вирусов
|
|
WO2018009466A1
(en)
|
2016-07-05 |
2018-01-11 |
Aduro Biotech, Inc. |
Locked nucleic acid cyclic dinucleotide compounds and uses thereof
|
|
CA3030765A1
(en)
|
2016-07-14 |
2018-01-18 |
Bristol-Myers Squibb Company |
Antibodies against tim3 and uses thereof
|
|
GB201612520D0
(en)
|
2016-07-19 |
2016-08-31 |
F-Star Beta Ltd |
Binding molecules
|
|
CA3031542A1
(en)
|
2016-07-20 |
2018-01-25 |
University Of Utah Research Foundation |
Cd229 car t cells and methods of use thereof
|
|
US20190292179A1
(en)
|
2016-07-21 |
2019-09-26 |
Bristol-Myers Squibb Company |
TGF Beta RECEPTOR ANTAGONISTS
|
|
EA039718B1
(ru)
*
|
2016-07-21 |
2022-03-03 |
Регенерон Фармасьютикалз, Инк. |
Антитела к lag3 и их применения
|
|
AU2017313496B2
(en)
|
2016-08-15 |
2023-09-21 |
Fuso Pharmaceutical Industries, Ltd. |
Anti-LAG-3 antibody
|
|
KR102585976B1
(ko)
|
2016-08-17 |
2023-10-05 |
컴퓨젠 엘티디. |
항-tigit 항체, 항-pvrig 항체 및 이들의 조합
|
|
US11351164B2
(en)
|
2016-08-26 |
2022-06-07 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
TW201811788A
(zh)
|
2016-09-09 |
2018-04-01 |
瑞士商諾華公司 |
作為抗病毒劑之多環吡啶酮化合物
|
|
MX2019003019A
(es)
|
2016-09-19 |
2019-09-19 |
I Mab |
Anticuerpos anti-gm-csf y usos de los mismos.
|
|
DK3515476T3
(da)
|
2016-09-21 |
2024-09-02 |
Amal Therapeutics Sa |
Fusion der omfatter et cellepenetrerende peptid, en multiepitop og en trl-peptidagnost til behandlingen af cancer
|
|
CA3036564A1
(en)
|
2016-09-23 |
2018-03-29 |
Elstar Therapeutics, Inc. |
Multispecific antibody molecules comprising lambda and kappa light chains
|
|
KR102708641B1
(ko)
|
2016-09-27 |
2024-09-24 |
더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 |
미생물유전체를 조정함으로써 면역 체크포인트 차단 요법을 증강시키는 방법
|
|
JOP20190061A1
(ar)
|
2016-09-28 |
2019-03-26 |
Novartis Ag |
مثبطات بيتا-لاكتاماز
|
|
EP3523331A1
(en)
|
2016-10-07 |
2019-08-14 |
Novartis AG |
Chimeric antigen receptors for the treatment of cancer
|
|
MA46529A
(fr)
*
|
2016-10-11 |
2019-08-21 |
Agenus Inc |
Anticorps anti-lag-3 et leurs procédés d'utilisation
|
|
AU2017342364B2
(en)
|
2016-10-12 |
2022-12-15 |
Board Of Regents, The University Of Texas System |
Methods and compositions for TUSC2 immunotherapy
|
|
CN110062766B
(zh)
*
|
2016-10-13 |
2023-12-15 |
正大天晴药业集团股份有限公司 |
抗lag-3抗体及组合物
|
|
TW201819380A
(zh)
|
2016-10-18 |
2018-06-01 |
瑞士商諾華公司 |
作為抗病毒劑之稠合四環吡啶酮化合物
|
|
WO2018081329A1
(en)
|
2016-10-28 |
2018-05-03 |
Merck Sharp & Dohme Corp. |
Purification process for removal of tyrosine sulfation antibody variants; purified compositions
|
|
JP2019533458A
(ja)
|
2016-11-01 |
2019-11-21 |
アナプティスバイオ インコーポレイティッド |
プログラム死１（ｐｄ−１）に対する抗体
|
|
UY37463A
(es)
|
2016-11-02 |
2018-05-31 |
Glaxosmithkline Ip No 2 Ltd |
Proteínas de unión
|
|
US10660909B2
(en)
|
2016-11-17 |
2020-05-26 |
Syntrix Biosystems Inc. |
Method for treating cancer using chemokine antagonists
|
|
US11279694B2
(en)
|
2016-11-18 |
2022-03-22 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Alvocidib prodrugs and their use as protein kinase inhibitors
|
|
US11135307B2
(en)
|
2016-11-23 |
2021-10-05 |
Mersana Therapeutics, Inc. |
Peptide-containing linkers for antibody-drug conjugates
|
|
WO2018099539A1
(en)
|
2016-11-29 |
2018-06-07 |
Horst Lindhofer |
Combination of t-cell redirecting multifunctional antibodies with immune checkpoint modulators and uses thereof
|
|
AU2017368332A1
(en)
|
2016-12-03 |
2019-06-13 |
Juno Therapeutics, Inc. |
Methods for modulation of CAR-T cells
|
|
WO2018106738A1
(en)
|
2016-12-05 |
2018-06-14 |
Massachusetts Institute Of Technology |
Brush-arm star polymers, conjugates and particles, and uses thereof
|
|
CN110300599B
(zh)
|
2016-12-07 |
2024-07-02 |
艾吉纳斯公司 |
抗体和其使用方法
|
|
IL266918B2
(en)
|
2016-12-07 |
2024-03-01 |
Agenus Inc |
Anti-ctla-4 antibodies and methods of use thereof
|
|
CN110381997A
(zh)
|
2016-12-12 |
2019-10-25 |
茂体外尔公司 |
用于治疗和预防癌症和感染性疾病的包含病毒基因治疗和免疫检查点抑制剂的方法和组合物
|
|
US20200095301A1
(en)
|
2016-12-14 |
2020-03-26 |
The Board Of Trustees Of The Leland Stanford Junior University |
Il-13 superkine: immune cell targeting constructs and methods of use thereof
|
|
CN108204958A
(zh)
*
|
2016-12-19 |
2018-06-26 |
伊缪泰普有限公司 |
结合测定
|
|
WO2018132279A1
(en)
|
2017-01-05 |
2018-07-19 |
Bristol-Myers Squibb Company |
Tgf beta receptor antagonists
|
|
TWI767976B
(zh)
|
2017-01-09 |
2022-06-21 |
美商提薩羅有限公司 |
用抗pd-1抗體治療癌症之方法
|
|
US10350266B2
(en)
|
2017-01-10 |
2019-07-16 |
Nodus Therapeutics, Inc. |
Method of treating cancer with a multiple integrin binding Fc fusion protein
|
|
CA3049656A1
(en)
|
2017-01-10 |
2018-07-19 |
Nodus Therapeutics |
Combination tumor treatment with an integrin-binding-fc fusion protein and immune modulator
|
|
CA3047600A1
(en)
|
2017-01-20 |
2018-07-26 |
Arcus Biosciences, Inc. |
Azolopyrimidine for the treatment of cancer-related disorders
|
|
MA46814B2
(fr)
|
2017-02-10 |
2022-09-30 |
Regeneron Pharma |
Anticorps anti-lag3 radiomarqués pour imagerie immuno-pet
|
|
US20200291089A1
(en)
|
2017-02-16 |
2020-09-17 |
Elstar Therapeutics, Inc. |
Multifunctional molecules comprising a trimeric ligand and uses thereof
|
|
WO2018151821A1
(en)
|
2017-02-17 |
2018-08-23 |
Bristol-Myers Squibb Company |
Antibodies to alpha-synuclein and uses thereof
|
|
NZ756678A
(en)
|
2017-02-22 |
2023-02-24 |
I Mab Biopharma Hangzhou Co Ltd |
Anti-lag-3 antibodies and uses thereof
|
|
WO2018152687A1
(en)
*
|
2017-02-22 |
2018-08-30 |
I-Mab |
Anti-lymphocyte activation gene-3 (lag-3) antibodies and uses thereof
|
|
WO2018160538A1
(en)
|
2017-02-28 |
2018-09-07 |
Mersana Therapeutics, Inc. |
Combination therapies of her2-targeted antibody-drug conjugates
|
|
IL269026B2
(en)
|
2017-03-31 |
2024-12-01 |
Bristol Myers Squibb Co |
Anti-pd-1 antibodies for treating tumors in high tumor mutational burden (tmb) patients
|
|
EP3601353A1
(en)
|
2017-03-31 |
2020-02-05 |
Five Prime Therapeutics, Inc. |
Combination therapy for cancer using anti-gitr antibodies
|
|
IL269395B2
(en)
|
2017-04-03 |
2025-01-01 |
Hoffmann La Roche |
Immunoconjugation of anti-PD-1 antibody with IL-2 or IL-15 mutation
|
|
PE20191741A1
(es)
|
2017-04-05 |
2019-12-12 |
Symphogen As |
Terapias combinadas dirigidas a pd-1, tim-3, y lag-3
|
|
PE20191463A1
(es)
|
2017-04-05 |
2019-10-16 |
Hoffmann La Roche |
Anticuerpos biespecificos de union especifica pd1 y lag3
|
|
AU2018247797B2
(en)
|
2017-04-05 |
2024-10-10 |
F. Hoffmann-La Roche Ag |
Anti-LAG3 antibodies
|
|
TWI788340B
(zh)
|
2017-04-07 |
2023-01-01 |
美商必治妥美雅史谷比公司 |
抗icos促效劑抗體及其用途
|
|
AU2018256406A1
(en)
|
2017-04-19 |
2019-10-17 |
Marengo Therapeutics, Inc. |
Multispecific molecules and uses thereof
|
|
ES2971065T3
(es)
|
2017-04-21 |
2024-06-03 |
Sillajen Inc |
Terapia de combinación de virus vaccinia oncolítica y un inhibidor de punto de control
|
|
EP3612030A4
(en)
|
2017-04-21 |
2021-04-28 |
Ikena Oncology, Inc. |
AHR INDOLE INHIBITORS AND THEIR USES
|
|
WO2018200430A1
(en)
|
2017-04-26 |
2018-11-01 |
Bristol-Myers Squibb Company |
Methods of antibody production that minimize disulfide bond reduction
|
|
AR111419A1
(es)
|
2017-04-27 |
2019-07-10 |
Novartis Ag |
Compuestos fusionados de indazol piridona como antivirales
|
|
CA3059468A1
(en)
*
|
2017-04-27 |
2018-11-01 |
Tesaro, Inc. |
Antibody agents directed against lymphocyte activation gene-3 (lag-3) and uses thereof
|
|
WO2018201047A1
(en)
|
2017-04-28 |
2018-11-01 |
Elstar Therapeutics, Inc. |
Multispecific molecules comprising a non-immunoglobulin heterodimerization domain and uses thereof
|
|
EP3615068A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
|
|
UY37695A
(es)
|
2017-04-28 |
2018-11-30 |
Novartis Ag |
Compuesto dinucleótido cíclico bis 2’-5’-rr-(3’f-a)(3’f-a) y usos del mismo
|
|
US20200055948A1
(en)
|
2017-04-28 |
2020-02-20 |
Novartis Ag |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
|
US11789010B2
(en)
|
2017-04-28 |
2023-10-17 |
Five Prime Therapeutics, Inc. |
Methods of treatment with CD80 extracellular domain polypeptides
|
|
AR111651A1
(es)
|
2017-04-28 |
2019-08-07 |
Novartis Ag |
Conjugados de anticuerpos que comprenden agonistas del receptor de tipo toll y terapias de combinación
|
|
AR111658A1
(es)
|
2017-05-05 |
2019-08-07 |
Novartis Ag |
2-quinolinonas tricíclicas como agentes antibacteriales
|
|
US11339218B2
(en)
|
2017-05-10 |
2022-05-24 |
Zhejiang Shimai Pharmaceutical Co., Ltd. |
Human monoclonal antibodies against LAG3 and uses thereof
|
|
US11066392B2
(en)
|
2017-05-12 |
2021-07-20 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
AU2018265856B2
(en)
|
2017-05-12 |
2023-04-27 |
Harpoon Therapeutics, Inc. |
Mesothelin binding proteins
|
|
JP7274426B2
(ja)
|
2017-05-16 |
2023-05-16 |
ブリストル－マイヤーズ スクイブ カンパニー |
抗ｇｉｔｒアゴニスト抗体での癌の処置
|
|
CN110636846B
(zh)
|
2017-05-17 |
2023-05-16 |
艾库斯生物科学有限公司 |
用于治疗癌症相关疾病的喹唑啉吡唑衍生物
|
|
US20200299400A1
(en)
|
2017-05-25 |
2020-09-24 |
Bristol-Myers Squibb Company |
Antibodies comprising modified heavy constant regions
|
|
US20200148777A1
(en)
|
2017-05-29 |
2020-05-14 |
Gamamabs Pharma |
Cancer-associated immunosuppression inhibitor
|
|
AU2018277559A1
(en)
|
2017-05-30 |
2019-10-17 |
Bristol-Myers Squibb Company |
Compositions comprising a combination of an anti-LAG-3 antibody, a PD-1 pathway inhibitor, and an immunotherapeutic agent
|
|
KR20240146108A
(ko)
|
2017-05-30 |
2024-10-07 |
브리스톨-마이어스 스큅 컴퍼니 |
Lag-3 양성 종양의 치료
|
|
AU2018275209A1
(en)
|
2017-05-30 |
2019-10-17 |
Bristol-Myers Squibb Company |
Compositions comprising an anti-LAG-3 antibody or an anti-LAG-3 antibody and an anti-PD-1 or anti-PD-L1 antibody
|
|
US20210246227A1
(en)
|
2017-05-31 |
2021-08-12 |
Elstar Therapeutics, Inc. |
Multispecific molecules that bind to myeloproliferative leukemia (mpl) protein and uses thereof
|
|
US20200181274A1
(en)
|
2017-06-01 |
2020-06-11 |
Novartis Ag |
Bispecific antibodies that bind cd 123 cd3
|
|
WO2018223004A1
(en)
|
2017-06-01 |
2018-12-06 |
Xencor, Inc. |
Bispecific antibodies that bind cd20 and cd3
|
|
KR20200054160A
(ko)
|
2017-06-02 |
2020-05-19 |
주노 쎄러퓨티크스 인코퍼레이티드 |
입양 세포 요법을 사용한 치료를 위한 물품 제조 및 방법
|
|
WO2018229715A1
(en)
|
2017-06-16 |
2018-12-20 |
Novartis Ag |
Compositions comprising anti-cd32b antibodies and methods of use thereof
|
|
CN111201035A
(zh)
|
2017-06-19 |
2020-05-26 |
梅迪塞纳医疗股份有限公司 |
Il-2超激动剂、激动剂及其融合体的用途和方法
|
|
WO2018235056A1
(en)
|
2017-06-22 |
2018-12-27 |
Novartis Ag |
Il-1beta binding antibodies for use in treating cancer
|
|
MX2019015885A
(es)
|
2017-06-22 |
2020-09-10 |
Novartis Ag |
Moleculas de anticuerpo que se unen a cd73 y usos de las mismas.
|
|
KR20200019865A
(ko)
|
2017-06-22 |
2020-02-25 |
노파르티스 아게 |
암 치료에 사용하기 위한 il-1베타 결합 항체
|
|
AU2018292618A1
(en)
|
2017-06-27 |
2019-12-19 |
Novartis Ag |
Dosage regimens for anti-TIM-3 antibodies and uses thereof
|
|
JP2020526194A
(ja)
|
2017-06-29 |
2020-08-31 |
ジュノー セラピューティクス インコーポレイテッド |
免疫療法薬と関連する毒性を評価するためのマウスモデル
|
|
US11236049B2
(en)
|
2017-06-30 |
2022-02-01 |
Bristol-Myers Squibb Company |
Amorphous and crystalline forms of IDO inhibitors
|
|
KR20200037250A
(ko)
|
2017-07-06 |
2020-04-08 |
메뤼스 엔.페. |
세포에 의해 발현되는 생물학적 활성을 조절하는 항체
|
|
CN116531502A
(zh)
*
|
2017-07-13 |
2023-08-04 |
南京维立志博生物科技有限公司 |
结合lag-3的抗体及其用途
|
|
MX2020000467A
(es)
|
2017-07-13 |
2020-08-03 |
Io Therapeutics Inc |
Compuestos retinoides y rexinoides inmunomoduladores en combinacion con inmunomoduladores para inmunoterapia contra cancer.
|
|
WO2019018730A1
(en)
|
2017-07-20 |
2019-01-24 |
Novartis Ag |
DOSAGE REGIMES FOR ANTI-LAG3 ANTIBODIES AND USES THEREOF
|
|
EP3658565B1
(en)
|
2017-07-28 |
2022-11-09 |
Bristol-Myers Squibb Company |
Cyclic dinucleotides as anticancer agents
|
|
CN118772242A
(zh)
|
2017-08-04 |
2024-10-15 |
拜斯科技术开发有限公司 |
Cd137特异性的双环肽配体
|
|
WO2019035938A1
(en)
|
2017-08-16 |
2019-02-21 |
Elstar Therapeutics, Inc. |
MULTISPECIFIC MOLECULES BINDING TO BCMA AND USES THEREOF
|
|
MX2020001793A
(es)
|
2017-08-17 |
2020-07-22 |
Ikena Oncology Inc |
Inhibidores del receptor de hidrocarburos de arilo (ahr) y usos de los mismos.
|
|
EP4364741A3
(en)
|
2017-08-18 |
2024-07-03 |
Cothera Bioscience, Inc. |
Polymorphic form of tg02
|
|
AU2018323955A1
(en)
*
|
2017-08-30 |
2020-03-19 |
Phanes Therapeutics, Inc. |
Anti-LAG-3 antibodies and uses thereof
|
|
KR102674630B1
(ko)
|
2017-08-31 |
2024-06-11 |
브리스톨-마이어스 스큅 컴퍼니 |
항암제로서의 시클릭 디뉴클레오티드
|
|
JP7316263B2
(ja)
|
2017-08-31 |
2023-07-27 |
ブリストル－マイヤーズ スクイブ カンパニー |
抗癌剤としての環状ジヌクレオチド
|
|
NZ761401A
(en)
|
2017-08-31 |
2022-11-25 |
Io Therapeutics Inc |
Rar selective agonists in combination with immune modulators for cancer immunotherapy
|
|
WO2019046498A1
(en)
|
2017-08-31 |
2019-03-07 |
Bristol-Myers Squibb Company |
CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS
|
|
US11497756B2
(en)
|
2017-09-12 |
2022-11-15 |
Sumitomo Pharma Oncology, Inc. |
Treatment regimen for cancers that are insensitive to BCL-2 inhibitors using the MCL-1 inhibitor alvocidib
|
|
IL273432B
(en)
|
2017-09-22 |
2022-09-01 |
Kymera Therapeutics Inc |
Protein degraders and uses thereof
|
|
EP3684366A4
(en)
|
2017-09-22 |
2021-09-08 |
Kymera Therapeutics, Inc. |
CRBN LIGANDS AND USES OF THE LATEST
|
|
BR112020006860A2
(pt)
|
2017-10-05 |
2020-10-20 |
Daiichi Sankyo Company, Limited |
composição para depleção de células t citotóxicas
|
|
US11649212B2
(en)
|
2017-10-09 |
2023-05-16 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
US11203592B2
(en)
|
2017-10-09 |
2021-12-21 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
US11660311B2
(en)
|
2017-10-10 |
2023-05-30 |
Bristol-Myers Squibb Company |
Cyclic dinucleotides as anticancer agents
|
|
US11230601B2
(en)
|
2017-10-10 |
2022-01-25 |
Tilos Therapeutics, Inc. |
Methods of using anti-lap antibodies
|
|
IL315737A
(en)
|
2017-10-13 |
2024-11-01 |
Harpoon Therapeutics Inc |
B-cell maturation antigen-binding proteins
|
|
US20200239577A1
(en)
|
2017-10-15 |
2020-07-30 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
EP3697801B1
(en)
|
2017-10-16 |
2024-11-20 |
Bristol-Myers Squibb Company |
Cyclic dinucleotides as anticancer agents
|
|
TW201916890A
(zh)
*
|
2017-10-17 |
2019-05-01 |
大陸商江蘇恆瑞醫藥股份有限公司 |
抗ｐｄ－１抗體和抗ｌａｇ－３抗體聯合在製備治療腫瘤的藥物中的用途
|
|
CA3079310A1
(en)
|
2017-10-18 |
2019-04-25 |
Vivia Biotech, S.L. |
Bite-activated car-t cells
|
|
WO2019081983A1
(en)
|
2017-10-25 |
2019-05-02 |
Novartis Ag |
CD32B TARGETING ANTIBODIES AND METHODS OF USE
|
|
US12031975B2
(en)
|
2017-11-01 |
2024-07-09 |
Juno Therapeutics, Inc. |
Methods of assessing or monitoring a response to a cell therapy
|
|
MX2020004243A
(es)
|
2017-11-01 |
2020-09-25 |
Juno Therapeutics Inc |
Receptores de anticuerpos y de antigenos quimericos especificos para el antigeno de maduracion de celulas b.
|
|
EP3704159A1
(en)
|
2017-11-01 |
2020-09-09 |
Bristol-Myers Squibb Company |
Immunostimulatory agonistic antibodies for use in treating cancer
|
|
WO2019090003A1
(en)
|
2017-11-01 |
2019-05-09 |
Juno Therapeutics, Inc. |
Chimeric antigen receptors specific for b-cell maturation antigen (bcma)
|
|
KR20200085303A
(ko)
|
2017-11-06 |
2020-07-14 |
브리스톨-마이어스 스큅 컴퍼니 |
Hpk1 억제제로서 유용한 이소푸라논 화합물
|
|
AU2018368731A1
(en)
|
2017-11-16 |
2020-05-14 |
Novartis Ag |
Combination therapies
|
|
EP3710455A1
(en)
|
2017-11-17 |
2020-09-23 |
Novartis AG |
Novel dihydroisoxazole compounds and their use for the treatment of hepatitis b
|
|
EP3717021A1
(en)
|
2017-11-27 |
2020-10-07 |
Mersana Therapeutics, Inc. |
Pyrrolobenzodiazepine antibody conjugates
|
|
JP2021509009A
(ja)
|
2017-11-30 |
2021-03-18 |
ノバルティス アーゲー |
Ｂｃｍａターゲティングキメラ抗原受容体及びその使用
|
|
JP7348899B2
(ja)
|
2017-12-08 |
2023-09-21 |
マレンゴ・セラピューティクス，インコーポレーテッド |
多重特異性分子及びその使用
|
|
JP2021506260A
(ja)
|
2017-12-15 |
2021-02-22 |
ジュノー セラピューティクス インコーポレイテッド |
抗ｃｃｔ５結合分子およびその使用方法
|
|
US11548948B2
(en)
|
2017-12-19 |
2023-01-10 |
F-Star Therapeutics Limited |
FC binding fragments comprising a PD-L1 antigen-binding site
|
|
WO2019123285A1
(en)
|
2017-12-20 |
2019-06-27 |
Novartis Ag |
Fused tricyclic pyrazolo-dihydropyrazinyl-pyridone compounds as antivirals
|
|
WO2019126691A1
(en)
|
2017-12-21 |
2019-06-27 |
Mersana Therapeutics, Inc. |
Pyrrolobenzodiazepine antibody conjugates
|
|
WO2019120269A1
(zh)
*
|
2017-12-22 |
2019-06-27 |
江苏恒瑞医药股份有限公司 |
Lag-3抗体药物组合物及其用途
|
|
IL315310A
(en)
|
2017-12-26 |
2024-10-01 |
Kymera Therapeutics Inc |
Irak degraders and uses thereof
|
|
CN115925943A
(zh)
*
|
2017-12-27 |
2023-04-07 |
信达生物制药(苏州)有限公司 |
抗pd-l1抗体及其用途
|
|
WO2019133747A1
(en)
|
2017-12-27 |
2019-07-04 |
Bristol-Myers Squibb Company |
Anti-cd40 antibodies and uses thereof
|
|
WO2019129137A1
(zh)
*
|
2017-12-27 |
2019-07-04 |
信达生物制药(苏州)有限公司 |
抗lag-3抗体及其用途
|
|
CN109970856B
(zh)
|
2017-12-27 |
2022-08-23 |
信达生物制药(苏州)有限公司 |
抗lag-3抗体及其用途
|
|
US11865081B2
(en)
|
2017-12-29 |
2024-01-09 |
Virogin Biotech Canada Ltd. |
Oncolytic viral delivery of therapeutic polypeptides
|
|
WO2019136112A1
(en)
|
2018-01-05 |
2019-07-11 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
US20200368268A1
(en)
|
2018-01-08 |
2020-11-26 |
Novartis Ag |
Immune-enhancing rnas for combination with chimeric antigen receptor therapy
|
|
WO2019140380A1
(en)
|
2018-01-12 |
2019-07-18 |
Kymera Therapeutics, Inc. |
Protein degraders and uses thereof
|
|
EP3737675A4
(en)
|
2018-01-12 |
2022-01-05 |
Kymera Therapeutics, Inc. |
Crbn ligands and uses thereof
|
|
KR20200108870A
(ko)
|
2018-01-12 |
2020-09-21 |
브리스톨-마이어스 스큅 컴퍼니 |
Tim3에 대한 항체 및 그의 용도
|
|
CN111542546B
(zh)
*
|
2018-01-18 |
2022-08-16 |
四川科伦博泰生物医药股份有限公司 |
抗lag-3抗体及其用途
|
|
CN118005640A
(zh)
|
2018-01-29 |
2024-05-10 |
默克专利股份有限公司 |
Gcn2抑制剂及其用途
|
|
IL312674A
(en)
|
2018-01-29 |
2024-07-01 |
Merck Patent Gmbh |
GCN2 inhibitors and uses thereof
|
|
JP2021511782A
(ja)
|
2018-01-31 |
2021-05-13 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
安定化された免疫グロブリンドメイン
|
|
US20210038659A1
(en)
|
2018-01-31 |
2021-02-11 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
|
JP2021511793A
(ja)
|
2018-01-31 |
2021-05-13 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
Ｌａｇ３に結合する抗原結合部位を含む二重特異性抗体
|
|
EP3746117A1
(en)
|
2018-01-31 |
2020-12-09 |
Celgene Corporation |
Combination therapy using adoptive cell therapy and checkpoint inhibitor
|
|
US10519187B2
(en)
|
2018-02-13 |
2019-12-31 |
Bristol-Myers Squibb Company |
Cyclic dinucleotides as anticancer agents
|
|
US20200399383A1
(en)
|
2018-02-13 |
2020-12-24 |
Novartis Ag |
Chimeric antigen receptor therapy in combination with il-15r and il15
|
|
US12090142B2
(en)
|
2018-02-22 |
2024-09-17 |
Board Of Regents, The University Of Texas System |
Combination therapy for the treatment of cancer
|
|
WO2019165315A1
(en)
|
2018-02-23 |
2019-08-29 |
Syntrix Biosystems Inc. |
Method for treating cancer using chemokine antagonists alone or in combination
|
|
WO2019165982A1
(en)
|
2018-02-28 |
2019-09-06 |
WuXi Biologics Ireland Limited |
Monoclonal antibody against human lag-3, method for preparing same, and use thereof
|
|
CN110204614B
(zh)
*
|
2018-02-28 |
2022-07-12 |
广州誉衡生物科技有限公司 |
抗人lag-3单克隆抗体及其制备方法和用途
|
|
CN111801331A
(zh)
|
2018-02-28 |
2020-10-20 |
诺华股份有限公司 |
吲哚-2-羰基化合物及其用于治疗乙型肝炎的用途
|
|
JP7250808B2
(ja)
|
2018-03-08 |
2023-04-03 |
ブリストル－マイヤーズ スクイブ カンパニー |
抗がん剤としての環状ジヌクレオチド
|
|
EP3765517A1
(en)
|
2018-03-14 |
2021-01-20 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
US20210009711A1
(en)
|
2018-03-14 |
2021-01-14 |
Elstar Therapeutics, Inc. |
Multifunctional molecules and uses thereof
|
|
JP2021518408A
(ja)
|
2018-03-19 |
2021-08-02 |
マルチビア インコーポレイテッド |
癌治療のための、癌抑制遺伝子治療法及びｃｄ１２２／ｃｄ１３２アゴニストを含む、方法及び組成物
|
|
JP7438180B2
(ja)
|
2018-03-20 |
2024-02-26 |
ウーシー バイオロジクス アイルランド リミテッド |
新規抗ｌａｇ－３抗体ポリペプチド
|
|
SG11202008593PA
(en)
|
2018-03-21 |
2020-10-29 |
Five Prime Therapeutics Inc |
ANTIBODIES BINDING TO VISTA AT ACIDIC pH
|
|
RU2020131241A
(ru)
|
2018-03-22 |
2022-04-22 |
Кейрес Аг (Keires Ag) |
Антагонистические антигенсвязывающие белки
|
|
AU2019236865A1
(en)
|
2018-03-23 |
2020-10-01 |
Bristol-Myers Squibb Company |
Antibodies against MICA and/or MICB and uses thereof
|
|
US10760075B2
(en)
|
2018-04-30 |
2020-09-01 |
Snipr Biome Aps |
Treating and preventing microbial infections
|
|
GB2587521B
(en)
|
2018-03-25 |
2023-06-21 |
Snipr Biome Aps |
Treating & preventing microbial infections
|
|
CN111971306A
(zh)
|
2018-03-30 |
2020-11-20 |
百时美施贵宝公司 |
治疗肿瘤的方法
|
|
JP7104458B2
(ja)
|
2018-04-02 |
2022-07-21 |
上海博威生物医薬有限公司 |
リンパ球活性化遺伝子－３（ｌａｇ－３）結合抗体およびその使用
|
|
CN110343178B
(zh)
*
|
2018-04-03 |
2022-07-22 |
上海开拓者生物医药有限公司 |
抗人lag-3单克隆抗体及其应用
|
|
US20210147547A1
(en)
|
2018-04-13 |
2021-05-20 |
Novartis Ag |
Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
|
|
EP3781162A1
(en)
|
2018-04-16 |
2021-02-24 |
Arrys Therapeutics, Inc. |
Ep4 inhibitors and use thereof
|
|
WO2019204665A1
(en)
|
2018-04-18 |
2019-10-24 |
Xencor, Inc. |
Pd-1 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and pd-1 antigen binding domains and uses thereof
|
|
SG11202010159RA
(en)
|
2018-04-18 |
2020-11-27 |
Xencor Inc |
Il-15/il-15ra heterodimeric fc fusion proteins and uses thereof
|
|
US20210047405A1
(en)
|
2018-04-27 |
2021-02-18 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
|
EP3788369A1
(en)
|
2018-05-01 |
2021-03-10 |
Novartis Ag |
Biomarkers for evaluating car-t cells to predict clinical outcome
|
|
WO2019213340A1
(en)
|
2018-05-03 |
2019-11-07 |
Bristol-Myers Squibb Company |
Uracil derivatives as mer-axl inhibitors
|
|
AR126019A1
(es)
|
2018-05-30 |
2023-09-06 |
Novartis Ag |
Anticuerpos frente a entpd2, terapias de combinación y métodos de uso de los anticuerpos y las terapias de combinación
|
|
WO2019232244A2
(en)
|
2018-05-31 |
2019-12-05 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
MA52785A
(fr)
|
2018-06-01 |
2021-04-14 |
Novartis Ag |
Molécules de liaison dirigées contre bcma et leurs utilisations
|
|
CA3102256A1
(en)
|
2018-06-01 |
2019-12-05 |
Novartis Ag |
Dosing of a bispecific antibody that bind cd123 and cd3
|
|
JP2021527082A
(ja)
*
|
2018-06-11 |
2021-10-11 |
イェール ユニバーシティーＹａｌｅ Ｕｎｉｖｅｒｓｉｔｙ |
新規な免疫チェックポイント阻害剤
|
|
SG11202011830SA
(en)
|
2018-06-13 |
2020-12-30 |
Novartis Ag |
Bcma chimeric antigen receptors and uses thereof
|
|
CN110606892B
(zh)
*
|
2018-06-14 |
2023-09-26 |
华博生物医药技术（上海）有限公司 |
一种高亲和力高生物活性的lag-3抗体及其应用
|
|
CN110615840A
(zh)
*
|
2018-06-19 |
2019-12-27 |
信达生物制药(苏州)有限公司 |
全人源的抗lag-3抗体及其应用
|
|
US11180531B2
(en)
|
2018-06-22 |
2021-11-23 |
Bicycletx Limited |
Bicyclic peptide ligands specific for Nectin-4
|
|
AU2019291792B2
(en)
|
2018-06-27 |
2022-09-29 |
Bristol-Myers Squibb Company |
Naphthyridinone compounds useful as T cell activators
|
|
CA3104654A1
(en)
|
2018-06-27 |
2020-01-02 |
Bristol-Myers Squibb Company |
Substituted naphthyridinone compounds useful as t cell activators
|
|
WO2020005003A1
(ko)
*
|
2018-06-29 |
2020-01-02 |
주식회사 와이바이오로직스 |
Lag-3에 특이적으로 결합하는 단클론항체 및 이의 용도
|
|
AU2019297451A1
(en)
|
2018-07-03 |
2021-01-28 |
Marengo Therapeutics, Inc. |
Anti-TCR antibody molecules and uses thereof
|
|
US11292792B2
(en)
|
2018-07-06 |
2022-04-05 |
Kymera Therapeutics, Inc. |
Tricyclic CRBN ligands and uses thereof
|
|
TW202428604A
(zh)
|
2018-07-09 |
2024-07-16 |
美商戊瑞治療有限公司 |
結合至ilt4的抗體
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
CN119241499A
(zh)
|
2018-07-10 |
2025-01-03 |
诺华股份有限公司 |
3-(5-羟基-1-氧代异吲哚啉-2-基)哌啶-2,6-二酮衍生物及其用途
|
|
CN112638948A
(zh)
|
2018-07-11 |
2021-04-09 |
戊瑞治疗有限公司 |
在酸性pH下结合至VISTA的抗体
|
|
GB201811408D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
CD137 Binding Molecules
|
|
KR20210032401A
(ko)
*
|
2018-07-16 |
2021-03-24 |
리제너론 파마슈티칼스 인코포레이티드 |
항-il36r 항체
|
|
WO2020018680A1
(en)
|
2018-07-18 |
2020-01-23 |
Arcus Biosciences, Inc. |
Solid forms of an azolopyrimidine compound
|
|
SG11202100373VA
(en)
|
2018-07-20 |
2021-02-25 |
Surface Oncology Inc |
Anti-cd112r compositions and methods
|
|
WO2020023355A1
(en)
|
2018-07-23 |
2020-01-30 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
US12145927B2
(en)
|
2018-07-23 |
2024-11-19 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
WO2020021465A1
(en)
|
2018-07-25 |
2020-01-30 |
Advanced Accelerator Applications (Italy) S.R.L. |
Method of treatment of neuroendocrine tumors
|
|
CN112739371A
(zh)
|
2018-07-26 |
2021-04-30 |
百时美施贵宝公司 |
用于治疗癌症的lag-3组合疗法
|
|
KR102666754B1
(ko)
*
|
2018-08-21 |
2024-05-17 |
에이비엘바이오 주식회사 |
항-pd-l1/항-lag3 이중 특이 항체 및 이의 용도
|
|
US10959986B2
(en)
|
2018-08-29 |
2021-03-30 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
US11253525B2
(en)
|
2018-08-29 |
2022-02-22 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
JP2022500499A
(ja)
|
2018-09-07 |
2022-01-04 |
ピク セラピューティクス， インコーポレイテッド |
Ｅｉｆ４ｅ阻害剤およびその使用
|
|
AU2019339777B2
(en)
|
2018-09-12 |
2022-09-01 |
Novartis Ag |
Antiviral pyridopyrazinedione compounds
|
|
EP3854805A4
(en)
|
2018-09-21 |
2022-08-24 |
Innovent Biologics (Suzhou) Co., Ltd. |
NOVEL INTERLEUKIN 2 AND ITS USE
|
|
WO2020061482A1
(en)
|
2018-09-21 |
2020-03-26 |
Harpoon Therapeutics, Inc. |
Egfr binding proteins and methods of use
|
|
US20210221863A1
(en)
|
2018-09-21 |
2021-07-22 |
Innovent Biologics (Suzhou) Co., Ltd. |
Novel interleukin-2 and use thereof
|
|
BR112021005769A2
(pt)
|
2018-09-25 |
2021-07-06 |
Harpoon Therapeutics Inc |
proteínas de ligação a dll3 e métodos de uso
|
|
JP7465272B2
(ja)
|
2018-09-27 |
2024-04-10 |
マレンゴ・セラピューティクス，インコーポレーテッド |
Ｃｓｆ１ｒ／ｃｃｒ２多特異性抗体
|
|
US20210347851A1
(en)
|
2018-09-28 |
2021-11-11 |
Novartis Ag |
Cd19 chimeric antigen receptor (car) and cd22 car combination therapies
|
|
EP3856779A1
(en)
|
2018-09-28 |
2021-08-04 |
Novartis AG |
Cd22 chimeric antigen receptor (car) therapies
|
|
MX2021003459A
(es)
|
2018-09-29 |
2021-06-18 |
Novartis Ag |
Proceso de fabricacion de un compuesto para la inhibicion de la actividad de shp2.
|
|
KR20210069641A
(ko)
|
2018-10-03 |
2021-06-11 |
젠코어 인코포레이티드 |
IL-12 이종이량체 Fc-융합 단백질
|
|
US11130802B2
(en)
|
2018-10-10 |
2021-09-28 |
Tilos Therapeutics, Inc. |
Anti-lap antibody variants
|
|
KR20210091710A
(ko)
|
2018-10-12 |
2021-07-22 |
젠코어 인코포레이티드 |
PD-1 표적화 IL-15/IL-15Rα Fc 융합 단백질 및 병용요법에서의 이의 용도
|
|
MX2021003903A
(es)
|
2018-10-19 |
2021-06-04 |
Bristol Myers Squibb Co |
Terapia combinada para el melanoma.
|
|
BR112021008012A2
(pt)
|
2018-10-29 |
2021-11-03 |
Mersana Therapeutics Inc |
Conjugados de anticorpo de cisteína engenheirada-fármaco com ligantes contendo peptídeo
|
|
US20230053449A1
(en)
|
2018-10-31 |
2023-02-23 |
Novartis Ag |
Dc-sign antibody drug conjugates
|
|
MX2021005024A
(es)
|
2018-11-01 |
2021-07-21 |
Juno Therapeutics Inc |
Metodos de tratamiento que utilizan receptores de antigenos quimericos especificos para antigeno de maduracion de celulas b.
|
|
MX2021005022A
(es)
|
2018-11-01 |
2021-09-08 |
Juno Therapeutics Inc |
Receptores de antigenos quimericos especificos para el miembro d del grupo 5 de la clase c del receptor acoplado a proteina g (gprc5d).
|
|
US11274150B2
(en)
|
2018-11-16 |
2022-03-15 |
Bristol-Myers Squibb Company |
Anti-human natural killer cell inhibitory receptor group 2A protein (NKG2A) antibodies
|
|
KR20210104713A
(ko)
|
2018-11-16 |
2021-08-25 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Ｂ 세포 악성 종양 치료를 위한 조작된 ｔ 세포 투약 방법
|
|
UY38476A
(es)
|
2018-11-16 |
2020-06-30 |
Arcus Biosciences Inc |
Inhibidores de arg1 y/o arg2
|
|
US20220088070A1
(en)
|
2018-11-30 |
2022-03-24 |
Juno Therapeutics, Inc. |
Methods for treatment using adoptive cell therapy
|
|
JP7623943B2
(ja)
|
2018-11-30 |
2025-01-29 |
カイメラ セラピューティクス， インコーポレイテッド |
Ｉｒａｋ分解剤およびそれらの使用
|
|
WO2020117988A1
(en)
|
2018-12-04 |
2020-06-11 |
Tolero Pharmaceuticals, Inc. |
Cdk9 inhibitors and polymorphs thereof for use as agents for treatment of cancer
|
|
FI3893924T3
(fi)
*
|
2018-12-13 |
2024-10-04 |
argenx BV |
Ihmisen komplementtitekijän C2B vasta-aineita sekä niiden käyttötapoja
|
|
EP3897853A1
(en)
|
2018-12-20 |
2021-10-27 |
Xencor, Inc. |
Targeted heterodimeric fc fusion proteins containing il-15/il-15ra and nkg2d antigen binding domains
|
|
JP2022514315A
(ja)
|
2018-12-20 |
2022-02-10 |
ノバルティス アーゲー |
３－（１－オキソイソインドリン－２－イル）ピペリジン－２，６－ジオン誘導体を含む投与計画及び薬剤組み合わせ
|
|
EP3670659A1
(en)
|
2018-12-20 |
2020-06-24 |
Abivax |
Biomarkers, and uses in treatment of viral infections, inflammations, or cancer
|
|
EP3898674A1
(en)
|
2018-12-21 |
2021-10-27 |
Novartis AG |
Use of il-1beta binding antibodies
|
|
US20220025036A1
(en)
|
2018-12-21 |
2022-01-27 |
Novartis Ag |
Use of il-1beta binding antibodies
|
|
WO2020128637A1
(en)
|
2018-12-21 |
2020-06-25 |
Novartis Ag |
Use of il-1 binding antibodies in the treatment of a msi-h cancer
|
|
EP3898677A1
(en)
|
2018-12-21 |
2021-10-27 |
OSE Immunotherapeutics |
Bifunctional anti-pd-1/il-7 molecule
|
|
US20200369762A1
(en)
|
2018-12-21 |
2020-11-26 |
Novartis Ag |
Use of il-1beta binding antibodies
|
|
CA3118182A1
(en)
|
2018-12-21 |
2020-06-25 |
Onxeo |
New conjugated nucleic acid molecules and their uses
|
|
WO2020154032A1
(en)
|
2019-01-23 |
2020-07-30 |
Massachusetts Institute Of Technology |
Combination immunotherapy dosing regimen for immune checkpoint blockade
|
|
US20220096651A1
(en)
|
2019-01-29 |
2022-03-31 |
Juno Therapeutics, Inc. |
Antibodies and chimeric antigen receptors specific for receptor tyrosine kinase like orphan receptor 1 (ror1)
|
|
MX2021009371A
(es)
|
2019-02-12 |
2021-09-10 |
Sumitomo Pharma Oncology Inc |
Formulaciones que comprenden inhibidores de proteina cinasa heterociclicos.
|
|
WO2020165374A1
(en)
|
2019-02-14 |
2020-08-20 |
Ose Immunotherapeutics |
Bifunctional molecule comprising il-15ra
|
|
AU2020222346B2
(en)
|
2019-02-15 |
2021-12-09 |
Novartis Ag |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
WO2020165833A1
(en)
|
2019-02-15 |
2020-08-20 |
Novartis Ag |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
CN111620949A
(zh)
*
|
2019-02-28 |
2020-09-04 |
三生国健药业（上海）股份有限公司 |
结合人lag-3的抗体、其制备方法和用途
|
|
EA202192555A1
(ru)
|
2019-03-19 |
2021-11-25 |
Фундасио Привада Институт Д'Инвестигасио Онколохика Де Валь Эброн |
Комбинированная терапия для лечения рака
|
|
JP2022525149A
(ja)
|
2019-03-20 |
2022-05-11 |
スミトモ ダイニッポン ファーマ オンコロジー， インコーポレイテッド |
ベネトクラクスが失敗した急性骨髄性白血病（ａｍｌ）の処置
|
|
EP3941463A1
(en)
|
2019-03-22 |
2022-01-26 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Compositions comprising pkm2 modulators and methods of treatment using the same
|
|
SG11202110449YA
(en)
|
2019-03-26 |
2021-10-28 |
Univ Michigan Regents |
Small molecule degraders of stat3
|
|
US20220185831A1
(en)
|
2019-03-29 |
2022-06-16 |
The Regents Of The University Of Michigan |
Stat3 protein degraders
|
|
JP2022527476A
(ja)
|
2019-03-29 |
2022-06-02 |
アーカス バイオサイエンシーズ，インコーポレーテッド |
同定されたアデノシンフィンガープリントを利用したがんの処置
|
|
WO2020201753A1
(en)
|
2019-04-02 |
2020-10-08 |
Bicycletx Limited |
Bicycle toxin conjugates and uses thereof
|
|
AU2020253633A1
(en)
|
2019-04-05 |
2021-11-04 |
Kymera Therapeutics, Inc. |
STAT degraders and uses thereof
|
|
EP3725370A1
(en)
|
2019-04-19 |
2020-10-21 |
ImmunoBrain Checkpoint, Inc. |
Modified anti-pd-l1 antibodies and methods and uses for treating a neurodegenerative disease
|
|
EP3962529A4
(en)
|
2019-04-30 |
2023-11-01 |
Dana-Farber Cancer Institute, Inc. |
METHOD FOR CANCER TREATMENT USING ANTI-CX3CR1 AND IMMUNE CHECKPOINT BLOCKING REAGENTS COMBINATIONS
|
|
GB201906118D0
(en)
|
2019-05-01 |
2019-06-12 |
Immutep S A |
Anti-LAG-3 binding molecules
|
|
SG11202111262XA
(en)
|
2019-05-13 |
2021-11-29 |
Regeneron Pharma |
Combination of pd-1 inhibitors and lag-3 inhibitors for enhanced efficacy in treating cancer
|
|
WO2020231713A1
(en)
|
2019-05-13 |
2020-11-19 |
Bristol-Myers Squibb Company |
AGONISTS OF ROR GAMMAt
|
|
WO2020231766A1
(en)
|
2019-05-13 |
2020-11-19 |
Bristol-Myers Squibb Company |
AGONISTS OF ROR GAMMAt
|
|
KR20220016155A
(ko)
|
2019-05-30 |
2022-02-08 |
브리스톨-마이어스 스큅 컴퍼니 |
면역-종양학 (i-o) 요법에 적합한 대상체를 확인하는 방법
|
|
JP2022534981A
(ja)
|
2019-05-30 |
2022-08-04 |
ブリストル－マイヤーズ スクイブ カンパニー |
細胞局在化シグネチャーおよび組み合わせ治療
|
|
CN114174538A
(zh)
|
2019-05-30 |
2022-03-11 |
百时美施贵宝公司 |
适合于免疫肿瘤学疗法的多肿瘤基因特征
|
|
CN110320367A
(zh)
*
|
2019-05-30 |
2019-10-11 |
广州医科大学附属第一医院（广州呼吸中心） |
基于lag-3的诊断试剂盒及其在帕金森病诊断产品上的应用
|
|
BR112021024224A2
(pt)
|
2019-05-31 |
2022-04-26 |
Ikena Oncology Inc |
Inibidores de tead e usos dos mesmos
|
|
CA3141414A1
(en)
|
2019-06-12 |
2020-12-17 |
Vanderbilt University |
Dibenzylamines as amino acid transport inhibitors
|
|
WO2020252264A1
(en)
|
2019-06-12 |
2020-12-17 |
AskGene Pharma, Inc. |
Novel il-15 prodrugs and methods of use thereof
|
|
WO2020252353A1
(en)
|
2019-06-12 |
2020-12-17 |
Vanderbilt University |
Amino acid transport inhibitors and the uses thereof
|
|
CN112079925A
(zh)
*
|
2019-06-13 |
2020-12-15 |
上海健信生物医药科技有限公司 |
靶向lag-3的抗体和双特异性抗体及其用途
|
|
JP2022538974A
(ja)
|
2019-06-26 |
2022-09-07 |
マサチューセッツ インスチテュート オブ テクノロジー |
免疫調節融合タンパク質－金属水酸化物錯体およびその方法
|
|
AU2020300619A1
(en)
|
2019-07-03 |
2022-01-27 |
Sumitomo Pharma Oncology, Inc. |
Tyrosine kinase non-receptor 1 (TNK1) inhibitors and uses thereof
|
|
IT201900011676A1
(it)
|
2019-07-12 |
2021-01-12 |
St Superiore Di Sanita |
Anticorpo ricombinante umano contro il recettore di membrana LAG3, suoi usi medici e diagnostici.
|
|
PH12021553233A1
(en)
|
2019-07-16 |
2022-09-19 |
Univ Michigan Regents |
Imidazopyrimidines as eed inhibitors and the use thereof
|
|
US20220306630A1
(en)
|
2019-08-06 |
2022-09-29 |
Bristol-Myers Squibb Company |
AGONISTS OF ROR GAMMAt
|
|
WO2021024020A1
(en)
|
2019-08-06 |
2021-02-11 |
Astellas Pharma Inc. |
Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer
|
|
WO2021041664A1
(en)
|
2019-08-27 |
2021-03-04 |
The Regents Of The University Of Michigan |
Cereblon e3 ligase inhibitors
|
|
AR119821A1
(es)
|
2019-08-28 |
2022-01-12 |
Bristol Myers Squibb Co |
Compuestos de piridopirimidinonilo sustituidos útiles como activadores de células t
|
|
PH12022550605A1
(en)
|
2019-09-13 |
2023-09-25 |
Nimbus Saturn Inc |
Hpk1 antagonists and uses thereof
|
|
JP2022548881A
(ja)
|
2019-09-18 |
2022-11-22 |
ノバルティス アーゲー |
Ｅｎｔｐｄ２抗体、組合せ療法並びに抗体及び組合せ療法を使用する方法
|
|
WO2021055698A1
(en)
|
2019-09-19 |
2021-03-25 |
Bristol-Myers Squibb Company |
Antibodies binding to vista at acidic ph
|
|
JP2022548775A
(ja)
|
2019-09-19 |
2022-11-21 |
ザ リージェンツ オブ ザ ユニヴァシティ オブ ミシガン |
スピロ環式アンドロゲン受容体タンパク質分解剤
|
|
KR20220066334A
(ko)
|
2019-09-22 |
2022-05-24 |
브리스톨-마이어스 스큅 컴퍼니 |
Lag-3 길항제 요법에 대한 정량적 공간 프로파일링
|
|
CN114667285A
(zh)
|
2019-09-26 |
2022-06-24 |
诺华股份有限公司 |
抗病毒吡唑并吡啶酮化合物
|
|
WO2021067863A2
(en)
|
2019-10-03 |
2021-04-08 |
Xencor, Inc. |
Targeted il-12 heterodimeric fc-fusion proteins
|
|
TW202128757A
(zh)
|
2019-10-11 |
2021-08-01 |
美商建南德克公司 |
具有改善之特性的 PD-1 標靶 IL-15/IL-15Rα FC 融合蛋白
|
|
WO2021079188A1
(en)
|
2019-10-21 |
2021-04-29 |
Novartis Ag |
Combination therapies with venetoclax and tim-3 inhibitors
|
|
CN114786680A
(zh)
|
2019-10-21 |
2022-07-22 |
诺华股份有限公司 |
Tim-3抑制剂及其用途
|
|
WO2021080682A1
(en)
|
2019-10-24 |
2021-04-29 |
Massachusetts Institute Of Technology |
Monoclonal antibodies that bind human cd161 and uses thereof
|
|
BR112022007632A2
(pt)
*
|
2019-10-25 |
2022-07-12 |
Daiichi Sankyo Co Ltd |
Composição farmacêutica e preparação de kit para tratamento de câncer, e, métodos para tratamento de câncer e de um paciente com câncer
|
|
JP2023500506A
(ja)
|
2019-11-04 |
2023-01-06 |
アストラゼネカ・アクチエボラーグ |
癌を治療するための組み合わせ療法
|
|
WO2021092221A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
WO2021092220A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
US20220411499A1
(en)
|
2019-11-08 |
2022-12-29 |
Bristol-Myers Squibb Company |
LAG-3 Antagonist Therapy for Melanoma
|
|
TWI836159B
(zh)
|
2019-11-19 |
2024-03-21 |
美商必治妥美雅史谷比公司 |
可作為helios蛋白質抑制劑之化合物
|
|
IL293326A
(en)
|
2019-11-26 |
2022-07-01 |
Ikena Oncology Inc |
Polymorphic carbazole derivatives and uses thereof
|
|
AU2020394441A1
(en)
|
2019-11-26 |
2022-06-02 |
Novartis Ag |
CD19 and CD22 chimeric antigen receptors and uses thereof
|
|
KR20220104794A
(ko)
|
2019-11-26 |
2022-07-26 |
브리스톨-마이어스 스큅 컴퍼니 |
(r)-n-(4-클로로페닐)-2-((1s,4s)-4-(6-플루오로퀴놀린-4-일)시클로헥실)프로판아미드의 염/공결정
|
|
WO2021113644A1
(en)
|
2019-12-05 |
2021-06-10 |
Multivir Inc. |
Combinations comprising a cd8+ t cell enhancer, an immune checkpoint inhibitor and radiotherapy for targeted and abscopal effects for the treatment of cancer
|
|
KR20220114063A
(ko)
|
2019-12-13 |
2022-08-17 |
큐진 인크. |
신규한 인터루킨-15 (ｉｌ-15) 융합 단백질 및 이의 용도
|
|
TW202136287A
(zh)
|
2019-12-17 |
2021-10-01 |
法商Ｏｓｅ免疫治療公司 |
包含il-7變體之雙官能分子
|
|
EP4076524A4
(en)
|
2019-12-17 |
2023-11-29 |
Kymera Therapeutics, Inc. |
IRAQ DEGRADERS AND USES THEREOF
|
|
KR20220145325A
(ko)
|
2019-12-17 |
2022-10-28 |
카이메라 쎄라퓨틱스 인코포레이티드 |
Irak 분해제 및 이의 용도
|
|
KR20220116257A
(ko)
|
2019-12-20 |
2022-08-22 |
노파르티스 아게 |
골수섬유증 및 골수이형성 증후군을 치료하기 위한, 데시타빈 또는 항 pd-1 항체 스파르탈리주맙을 포함하거나 또는 포함하지 않는, 항 tim-3 항체 mbg453 및 항 tgf-베타 항체 nis793의 조합물
|
|
WO2021126967A1
(en)
*
|
2019-12-20 |
2021-06-24 |
Merck Sharp & Dohme Corp. |
Lag3 antagonist cell based potency assay
|
|
IL294148A
(en)
|
2019-12-23 |
2022-08-01 |
Bristol Myers Squibb Co |
Substituted quinazolinyl compounds useful as t cell activators
|
|
CN115297931A
(zh)
|
2019-12-23 |
2022-11-04 |
凯麦拉医疗公司 |
Smarca降解剂和其用途
|
|
AR120823A1
(es)
|
2019-12-23 |
2022-03-23 |
Bristol Myers Squibb Co |
Compuestos bicíclicos sustituidos útiles como activadores de células t
|
|
MX2022007130A
(es)
|
2019-12-23 |
2022-07-11 |
Bristol Myers Squibb Co |
Derivados de piperazina sustituidos utiles como activadores de celulas t.
|
|
BR112022012204A2
(pt)
|
2019-12-23 |
2022-09-13 |
Bristol Myers Squibb Co |
Compostos de heteroarila substituída úteis como ativadores de célula t
|
|
CN115103841B
(zh)
|
2019-12-23 |
2024-12-27 |
百时美施贵宝公司 |
可用作t细胞激活剂的经取代的喹啉酮基哌嗪化合物
|
|
WO2021138407A2
(en)
|
2020-01-03 |
2021-07-08 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to cd33 and uses thereof
|
|
CN115996950A
(zh)
|
2020-01-06 |
2023-04-21 |
高诚生物医药(香港)有限公司 |
抗tnfr2抗体和其用途
|
|
CN115279771A
(zh)
|
2020-01-15 |
2022-11-01 |
缆图药品公司 |
Map4k1抑制剂
|
|
CN114980902A
(zh)
|
2020-01-17 |
2022-08-30 |
诺华股份有限公司 |
用于治疗骨髓增生异常综合征或慢性粒单核细胞白血病的包含tim-3抑制剂和低甲基化药物的组合
|
|
EP4100426A1
(en)
|
2020-02-06 |
2022-12-14 |
Bristol-Myers Squibb Company |
Il-10 and uses thereof
|
|
WO2021171264A1
(en)
|
2020-02-28 |
2021-09-02 |
Novartis Ag |
Dosing of a bispecific antibody that binds cd123 and cd3
|
|
MX2022010944A
(es)
|
2020-03-03 |
2022-11-09 |
Pic Therapeutics Inc |
Inhibidores del factor de iniciacion de traduccion eucariotica 4e (eif4e) y sus usos.
|
|
CN115485302A
(zh)
|
2020-03-09 |
2022-12-16 |
百时美施贵宝公司 |
具有增强的激动剂活性的针对cd40的抗体
|
|
PE20230673A1
(es)
|
2020-03-19 |
2023-04-20 |
Arcus Biosciences Inc |
Compuestos de tetralina y tetrahidroquinolina como inhibidores de hif-2alfa
|
|
JP2023518423A
(ja)
|
2020-03-19 |
2023-05-01 |
カイメラ セラピューティクス， インコーポレイテッド |
Ｍｄｍ２分解剤およびそれらの使用
|
|
TW202140441A
(zh)
|
2020-03-23 |
2021-11-01 |
美商必治妥美雅史谷比公司 |
經取代之側氧基異吲哚啉化合物
|
|
US20230159573A1
(en)
|
2020-03-26 |
2023-05-25 |
The Regents Of The University Of Michigan |
Small molecule stat protein degraders
|
|
EP4132971A1
(en)
|
2020-04-09 |
2023-02-15 |
Merck Sharp & Dohme LLC |
Affinity matured anti-lap antibodies and uses thereof
|
|
MX2022012533A
(es)
|
2020-04-10 |
2022-12-13 |
Juno Therapeutics Inc |
Metodos y usos relacionados con terapia celular dise?ada con un receptor de antigeno quimerico dirigido al antigeno de maduracion de celulas b.
|
|
US20230192867A1
(en)
|
2020-05-15 |
2023-06-22 |
Bristol-Myers Squibb Company |
Antibodies to garp
|
|
CA3176564A1
(en)
*
|
2020-05-27 |
2021-12-02 |
Agilent Technologies, Inc. |
Anti-human lag-3 antibodies and their use in immunohistochemistry (ihc)
|
|
CR20220611A
(es)
|
2020-06-02 |
2023-06-07 |
Arcus Biosciences Inc |
Anticuerpos anti-tigit
|
|
EP4161521A4
(en)
|
2020-06-03 |
2024-07-10 |
Kymera Therapeutics, Inc. |
DEUTERED IRAQ DEGRADERS AND USES THEREOF
|
|
TW202210483A
(zh)
|
2020-06-03 |
2022-03-16 |
美商凱麥拉醫療公司 |
Irak降解劑之結晶型
|
|
WO2021245071A1
(en)
|
2020-06-03 |
2021-12-09 |
Mv Biotherapeutics Sa |
Combination of an atp-hydrolyzing enzyme and an immune checkpoint modulator and uses thereof
|
|
CN111808192B
(zh)
*
|
2020-06-05 |
2022-02-15 |
北京天广实生物技术股份有限公司 |
结合lag3的抗体及其用途
|
|
WO2021258010A1
(en)
|
2020-06-19 |
2021-12-23 |
Gossamer Bio Services, Inc. |
Oxime compounds useful as t cell activators
|
|
TW202214857A
(zh)
|
2020-06-19 |
2022-04-16 |
法商昂席歐公司 |
新型結合核酸分子及其用途
|
|
EP4168007A1
(en)
|
2020-06-23 |
2023-04-26 |
Novartis AG |
Dosing regimen comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
AU2021306613A1
(en)
|
2020-07-07 |
2023-02-02 |
BioNTech SE |
Therapeutic RNA for HPV-positive cancer
|
|
US20230233690A1
(en)
|
2020-07-10 |
2023-07-27 |
The Regents Of The University Of Michigan |
Androgen receptor protein degraders
|
|
US20230257365A1
(en)
|
2020-07-10 |
2023-08-17 |
The Regents Of The University Of Michigan |
Small molecule androgen receptor protein degraders
|
|
TW202220653A
(zh)
|
2020-07-30 |
2022-06-01 |
美商凱麥拉醫療公司 |
治療突變淋巴瘤之方法
|
|
WO2022029573A1
(en)
|
2020-08-03 |
2022-02-10 |
Novartis Ag |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
IL300537A
(en)
|
2020-08-10 |
2023-04-01 |
Gv20 Therapeutics Llc |
Compositions and methods for treating autoimmune diseases and cancer by targeting IGSF8
|
|
JP2023537412A
(ja)
|
2020-08-13 |
2023-08-31 |
ブリストル－マイヤーズ スクイブ カンパニー |
目的の細胞を標的とするためのｉｌ－２の向け直し方法
|
|
JP2023538906A
(ja)
|
2020-08-17 |
2023-09-12 |
バイシクルティーエクス・リミテッド |
ネクチン－４に特異的な二環コンジュゲート及びその使用
|
|
EP4204458A4
(en)
|
2020-08-26 |
2024-10-09 |
Marengo Therapeutics, Inc. |
METHODS FOR DETECTION OF TRBC1 OR TRBC2
|
|
EP4204095A1
(en)
|
2020-08-28 |
2023-07-05 |
Bristol-Myers Squibb Company |
Lag-3 antagonist therapy for hepatocellular carcinoma
|
|
WO2022043557A1
(en)
|
2020-08-31 |
2022-03-03 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
|
EP4204020A1
(en)
|
2020-08-31 |
2023-07-05 |
Advanced Accelerator Applications International S.A. |
Method of treating psma-expressing cancers
|
|
CA3190660A1
(en)
|
2020-08-31 |
2022-03-03 |
George C. Lee |
Cell localization signature and immunotherapy
|
|
IL300060A
(en)
|
2020-09-14 |
2023-03-01 |
Boehringer Ingelheim Int |
Heterologous primary boost vaccine
|
|
CA3187272A1
(en)
|
2020-10-08 |
2022-04-14 |
Thorsten Ross |
Trispecific binders
|
|
EP4228764A1
(en)
|
2020-10-14 |
2023-08-23 |
Five Prime Therapeutics, Inc. |
Anti-c-c chemokine receptor 8 (ccr8) antibodies and methods of use thereof
|
|
JP2023548051A
(ja)
|
2020-10-23 |
2023-11-15 |
ブリストル－マイヤーズ スクイブ カンパニー |
肺がんのためのｌａｇ－３アンタゴニスト療法
|
|
WO2022097060A1
(en)
|
2020-11-06 |
2022-05-12 |
Novartis Ag |
Cd19 binding molecules and uses thereof
|
|
WO2022112198A1
(en)
|
2020-11-24 |
2022-06-02 |
Worldwide Innovative Network |
Method to select the optimal immune checkpoint therapies
|
|
EP4255895A1
(en)
|
2020-12-02 |
2023-10-11 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
|
WO2022120353A1
(en)
|
2020-12-02 |
2022-06-09 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
|
EP4255929A2
(en)
|
2020-12-02 |
2023-10-11 |
Vib Vzw |
An ltbr agonist in combination therapy against cancer
|
|
WO2022120179A1
(en)
|
2020-12-03 |
2022-06-09 |
Bristol-Myers Squibb Company |
Multi-tumor gene signatures and uses thereof
|
|
CA3204091A1
(en)
|
2020-12-08 |
2022-06-16 |
Infinity Pharmaceuticals, Inc. |
Eganelisib for use in the treatment of pd-l1 negative cancer
|
|
CN114621344B
(zh)
*
|
2020-12-10 |
2022-08-30 |
北京东方百泰生物科技股份有限公司 |
一种抗lag-3单克隆抗体的纯化方法
|
|
TW202237119A
(zh)
|
2020-12-10 |
2022-10-01 |
美商住友製藥腫瘤公司 |
Ａｌｋ﹘５抑制劑和彼之用途
|
|
JP2024501207A
(ja)
|
2020-12-16 |
2024-01-11 |
ゴッサマー バイオ サービシズ、インコーポレイテッド |
Ｔ細胞活性化剤として有用な化合物
|
|
WO2022135667A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Therapeutic rna for treating cancer
|
|
TW202245808A
(zh)
|
2020-12-21 |
2022-12-01 |
德商拜恩迪克公司 |
用於治療癌症之治療性ｒｎａ
|
|
WO2022135666A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Treatment schedule for cytokine proteins
|
|
CA3196999A1
(en)
|
2020-12-28 |
2022-07-07 |
Masano HUANG |
Methods of treating tumors
|
|
AU2021411486A1
(en)
|
2020-12-28 |
2023-06-29 |
Bristol-Myers Squibb Company |
Antibody compositions and methods of use thereof
|
|
CN116867758A
(zh)
|
2020-12-30 |
2023-10-10 |
凯麦拉医疗公司 |
Irak降解剂和其用途
|
|
WO2022148781A1
(en)
|
2021-01-05 |
2022-07-14 |
Institut Curie |
Combination of mcoln activators and immune checkpoint inhibitors
|
|
US20240325554A1
(en)
|
2021-01-11 |
2024-10-03 |
Bicycle TX Limited |
Methods for treating cancer
|
|
EP4288430A1
(en)
|
2021-02-02 |
2023-12-13 |
Liminal Biosciences Limited |
Gpr84 antagonists and uses thereof
|
|
CN117098757A
(zh)
|
2021-02-02 |
2023-11-21 |
里米诺生物科学有限公司 |
Gpr84拮抗剂和其用途
|
|
MX2023009100A
(es)
|
2021-02-03 |
2023-09-25 |
Mozart Therapeutics Inc |
Agentes aglutinantes y métodos para usar los mismos.
|
|
WO2022169921A1
(en)
|
2021-02-04 |
2022-08-11 |
Bristol-Myers Squibb Company |
Benzofuran compounds as sting agonists
|
|
PE20231505A1
(es)
|
2021-02-12 |
2023-09-26 |
Hoffmann La Roche |
Derivados de tetrahidroazepina biciclicos para el tratamiento del cancer
|
|
US12171768B2
(en)
|
2021-02-15 |
2024-12-24 |
Kymera Therapeutics, Inc. |
IRAK4 degraders and uses thereof
|
|
WO2022174269A1
(en)
|
2021-02-15 |
2022-08-18 |
Kymera Therapeutics, Inc. |
Irak4 degraders and uses thereof
|
|
US20220275090A1
(en)
|
2021-02-22 |
2022-09-01 |
Janssen Biotech, Inc. |
Combination Therapies with Anti-CD38 Antibodies and PARP or Adenosine Receptor Inhibitors
|
|
WO2022187423A1
(en)
|
2021-03-03 |
2022-09-09 |
The Regents Of The University Of Michigan |
Cereblon ligands
|
|
US20240190874A1
(en)
|
2021-03-03 |
2024-06-13 |
The Regents Of The University Of Michigan |
Small molecule degraders of androgen receptor
|
|
US11926625B2
(en)
|
2021-03-05 |
2024-03-12 |
Nimbus Saturn, Inc. |
HPK1 antagonists and uses thereof
|
|
JP2024510176A
(ja)
|
2021-03-08 |
2024-03-06 |
ブループリント メディシンズ コーポレイション |
Ｍａｐ４ｋ１阻害剤
|
|
US11918582B2
(en)
|
2021-03-15 |
2024-03-05 |
Rapt Therapeutics, Inc. |
Pyrazole pyrimidine compounds and uses thereof
|
|
KR20240005700A
(ko)
|
2021-03-29 |
2024-01-12 |
주노 쎄러퓨티크스 인코퍼레이티드 |
체크포인트 억제제 요법 및 car t 세포 요법의 조합을 사용한 투여 및 치료 방법
|
|
JP2024513011A
(ja)
|
2021-03-29 |
2024-03-21 |
ニンバス サターン， インコーポレイテッド |
Ｈｐｋ１アンタゴニスト及びその使用
|
|
EP4314068A1
(en)
|
2021-04-02 |
2024-02-07 |
The Regents Of The University Of California |
Antibodies against cleaved cdcp1 and uses thereof
|
|
EP4320125A1
(en)
|
2021-04-05 |
2024-02-14 |
Bristol-Myers Squibb Company |
Pyridinyl substituted oxoisoindoline compounds for the treatment of cancer
|
|
EP4320112A1
(en)
|
2021-04-06 |
2024-02-14 |
Bristol-Myers Squibb Company |
Pyridinyl substituted oxoisoindoline compounds
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗ＴＧＦβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
WO2022216993A2
(en)
|
2021-04-08 |
2022-10-13 |
Marengo Therapeutics, Inc. |
Multifuntional molecules binding to tcr and uses thereof
|
|
EP4320155A1
(en)
|
2021-04-09 |
2024-02-14 |
Ose Immunotherapeutics |
New scaffold for bifunctional molecules with improved properties
|
|
US20240182572A1
(en)
|
2021-04-09 |
2024-06-06 |
Ose Immunotherapeutics |
Scaffold for bifunctional molecules comprising pd-1 or cd28 and sirp binding domains
|
|
MX2023012060A
(es)
|
2021-04-13 |
2024-01-22 |
Nuvalent Inc |
Heterociclos con sustitucion amino para tratar canceres con mutaciones de egfr.
|
|
WO2022221866A1
(en)
|
2021-04-16 |
2022-10-20 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
|
BR112023023223A2
(pt)
|
2021-05-07 |
2024-01-30 |
Kymera Therapeutics Inc |
Degradadores de cdk2 e usos dos mesmos
|
|
US20240285740A1
(en)
|
2021-05-12 |
2024-08-29 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for treating cancer
|
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
|
US20240246967A1
(en)
|
2021-05-21 |
2024-07-25 |
Arcus Biosciences, Inc. |
Axl compounds
|
|
EP4341262A1
(en)
|
2021-05-21 |
2024-03-27 |
Arcus Biosciences, Inc. |
Axl inhibitor compounds
|
|
WO2022251853A1
(en)
|
2021-05-25 |
2022-12-01 |
Edelweiss Immune Inc |
C-x-c motif chemokine receptor 6 (cxcr6) binding molecules, and methods of using the same
|
|
TW202307210A
(zh)
|
2021-06-01 |
2023-02-16 |
瑞士商諾華公司 |
Ｃｄ１９和ｃｄ２２嵌合抗原受體及其用途
|
|
US20240327544A1
(en)
|
2021-07-13 |
2024-10-03 |
BioNTech SE |
Multispecific binding agents against cd40 and cd137 in combination therapy for cancer
|
|
US12202844B2
(en)
|
2021-07-14 |
2025-01-21 |
Blueprint Medicines Corporation |
MAP4K1 inhibitors
|
|
AR126453A1
(es)
|
2021-07-15 |
2023-10-11 |
Blueprint Medicines Corp |
Inhibidores de map4k1
|
|
IL308154A
(en)
|
2021-07-30 |
2023-12-01 |
Affimed Gmbh |
Double structure antibodies
|
|
CN118019739A
(zh)
|
2021-08-25 |
2024-05-10 |
皮克医疗公司 |
Eif4e抑制剂及其用途
|
|
TW202315621A
(zh)
|
2021-08-25 |
2023-04-16 |
美商皮克醫療公司 |
Ｅｉｆ４ｅ抑制劑及其用途
|
|
CN118201914A
(zh)
|
2021-09-08 |
2024-06-14 |
雷多纳治疗公司 |
Papd5和/或papd7抑制剂4-氧代-1,4-二氢喹啉-3-甲酸衍生物
|
|
TW202333802A
(zh)
|
2021-10-11 |
2023-09-01 |
德商拜恩迪克公司 |
用於肺癌之治療性rna(二)
|
|
WO2023076876A1
(en)
|
2021-10-26 |
2023-05-04 |
Mozart Therapeutics, Inc. |
Modulation of immune responses to viral vectors
|
|
IL312348A
(en)
|
2021-10-29 |
2024-06-01 |
Arcus Biosciences Inc |
HIF-2ALPHA inhibitors and methods of using it
|
|
CA3224890A1
(en)
|
2021-10-29 |
2023-05-04 |
Bristol-Myers Squibb Company |
Lag-3 antagonist therapy for hematological cancer
|
|
CN118302168A
(zh)
|
2021-10-29 |
2024-07-05 |
凯麦拉医疗公司 |
Irak4降解剂和其制备
|
|
US20230136301A1
(en)
|
2021-11-03 |
2023-05-04 |
Janssen Biotech, Inc. |
Corticosteriod Reduction in Treatment with Anti-CD38 Antibody
|
|
CN118660964A
(zh)
|
2021-12-16 |
2024-09-17 |
瓦莱里奥治疗公司 |
新型缀合核酸分子及其用途
|
|
WO2023114984A1
(en)
|
2021-12-17 |
2023-06-22 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
|
WO2023122778A1
(en)
|
2021-12-22 |
2023-06-29 |
Gossamer Bio Services, Inc. |
Pyridazinone derivatives useful as t cell activators
|
|
WO2023122777A1
(en)
|
2021-12-22 |
2023-06-29 |
Gossamer Bio Services, Inc. |
Oxime derivatives useful as t cell activators
|
|
WO2023122772A1
(en)
|
2021-12-22 |
2023-06-29 |
Gossamer Bio Services, Inc. |
Oxime derivatives useful as t cell activators
|
|
MX2024008831A
(es)
|
2022-01-26 |
2024-07-25 |
Bristol Myers Squibb Co |
Terapia combinada para carcinoma hepatocelular.
|
|
JP2025504059A
(ja)
|
2022-01-31 |
2025-02-06 |
カイメラ セラピューティクス， インコーポレイテッド |
Ｉｒａｋデグレーダー及びその使用
|
|
WO2023150186A1
(en)
|
2022-02-01 |
2023-08-10 |
Arvinas Operations, Inc. |
Dgk targeting compounds and uses thereof
|
|
EP4479388A1
(en)
|
2022-02-14 |
2024-12-25 |
Gilead Sciences, Inc. |
Antiviral naphthyridinone compounds
|
|
WO2023164638A1
(en)
|
2022-02-25 |
2023-08-31 |
Bristol-Myers Squibb Company |
Combination therapy for colorectal carcinoma
|
|
WO2023168404A1
(en)
|
2022-03-04 |
2023-09-07 |
Bristol-Myers Squibb Company |
Methods of treating a tumor
|
|
CN119156403A
(zh)
|
2022-03-08 |
2024-12-17 |
阿伦蒂斯治疗股份公司 |
抗紧密连接蛋白-1抗体增加t细胞可用性的用途
|
|
WO2023173053A1
(en)
|
2022-03-10 |
2023-09-14 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
|
WO2023173057A1
(en)
|
2022-03-10 |
2023-09-14 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
|
WO2023178201A2
(en)
*
|
2022-03-15 |
2023-09-21 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods of identifying anti-lag-3 agents
|
|
EP4493195A1
(en)
|
2022-03-15 |
2025-01-22 |
Compugen Ltd. |
Il-18bp antagonist antibodies and their use in monotherapy and combination therapy in the treatment of cancer
|
|
KR20240159621A
(ko)
|
2022-03-18 |
2024-11-05 |
브리스톨-마이어스 스큅 컴퍼니 |
폴리펩티드를 단리하는 방법
|
|
WO2023211889A1
(en)
|
2022-04-25 |
2023-11-02 |
Ikena Oncology, Inc. |
Polymorphic compounds and uses thereof
|
|
WO2023214325A1
(en)
|
2022-05-05 |
2023-11-09 |
Novartis Ag |
Pyrazolopyrimidine derivatives and uses thereof as tet2 inhibitors
|
|
AU2023276599A1
(en)
|
2022-05-25 |
2024-12-05 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
|
AU2023281061A1
(en)
|
2022-06-02 |
2024-12-05 |
Bristol-Myers Squibb Company |
Antibody compositions and methods of use thereof
|
|
WO2023250400A1
(en)
|
2022-06-22 |
2023-12-28 |
Juno Therapeutics, Inc. |
Treatment methods for second line therapy of cd19-targeted car t cells
|
|
GB202209518D0
(en)
|
2022-06-29 |
2022-08-10 |
Snipr Biome Aps |
Treating & preventing E coli infections
|
|
WO2024003360A1
(en)
|
2022-07-01 |
2024-01-04 |
Institut Curie |
Biomarkers and uses thereof for the treatment of neuroblastoma
|
|
WO2024015251A1
(en)
|
2022-07-15 |
2024-01-18 |
Arcus Biosciences, Inc. |
Inhibitors of hpk1 and methods of use thereof
|
|
WO2024020034A1
(en)
|
2022-07-20 |
2024-01-25 |
Arcus Biosciences, Inc. |
Cbl-b inhibitors and methods of use thereof
|
|
WO2024028363A1
(en)
|
2022-08-02 |
2024-02-08 |
Liminal Biosciences Limited |
Heteroaryl carboxamide and related gpr84 antagonists and uses thereof
|
|
WO2024028386A1
(en)
|
2022-08-02 |
2024-02-08 |
Ose Immunotherapeutics |
Multifunctional molecule directed against cd28
|
|
TW202415650A
(zh)
|
2022-08-02 |
2024-04-16 |
英商利米那生物科技有限公司 |
芳基-三唑基及相關gpr84拮抗劑及其用途
|
|
TW202416972A
(zh)
|
2022-08-02 |
2024-05-01 |
英商利米那生物科技有限公司 |
經取代之吡啶酮gpr84拮抗劑及其用途
|
|
AU2023320568A1
(en)
|
2022-08-05 |
2025-02-06 |
Juno Therapeutics, Inc. |
Chimeric antigen receptors specific for gprc5d and bcma
|
|
WO2024036100A1
(en)
|
2022-08-08 |
2024-02-15 |
Bristol-Myers Squibb Company |
Substituted tetrazolyl compounds useful as t cell activators
|
|
WO2024036101A1
(en)
|
2022-08-09 |
2024-02-15 |
Bristol-Myers Squibb Company |
Tertiary amine substituted bicyclic compounds useful as t cell activators
|
|
WO2024033458A1
(en)
|
2022-08-11 |
2024-02-15 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydroazepine derivatives
|
|
WO2024033457A1
(en)
|
2022-08-11 |
2024-02-15 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydrothiazepine derivatives
|
|
AU2023322637A1
(en)
|
2022-08-11 |
2024-11-14 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydrothiazepine derivatives
|
|
AU2023322638A1
(en)
|
2022-08-11 |
2024-11-28 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydrothiazepine derivatives
|
|
WO2024040195A1
(en)
|
2022-08-17 |
2024-02-22 |
Capstan Therapeutics, Inc. |
Conditioning for in vivo immune cell engineering
|
|
TW202421150A
(zh)
|
2022-09-14 |
2024-06-01 |
美商阿克思生物科學有限公司 |
艾魯美冷之分散體
|
|
WO2024081385A1
(en)
|
2022-10-14 |
2024-04-18 |
Arcus Biosciences, Inc. |
Hpk1 inhibitors and methods of use thereof
|
|
WO2024086718A1
(en)
|
2022-10-20 |
2024-04-25 |
Arcus Biosciences, Inc. |
Lyophilized formulations of cd73 compounds
|
|
WO2024089418A1
(en)
|
2022-10-24 |
2024-05-02 |
Cancer Research Technology Limited |
Tumour sensitisation to checkpoint inhibitors with redox status modifier
|
|
WO2024089417A1
(en)
|
2022-10-24 |
2024-05-02 |
Memorial Sloan-Kettering Cancer Center |
Tumour stratification for responsiveness to an immune checkpoint inhibitor
|
|
TW202430148A
(zh)
|
2022-11-22 |
2024-08-01 |
美商皮克醫療公司 |
ｅＩＦ４Ｅ抑制劑及其用途
|
|
WO2024116140A1
(en)
|
2022-12-01 |
2024-06-06 |
Medimmune Limited |
Combination therapy for treatment of cancer comprising anti-pd-l1 and anti-cd73 antibodies
|
|
WO2024129778A2
(en)
|
2022-12-13 |
2024-06-20 |
Juno Therapeutics, Inc. |
Chimeric antigen receptors specific for baff-r and cd19 and methods and uses thereof
|
|
WO2024126457A1
(en)
|
2022-12-14 |
2024-06-20 |
Astellas Pharma Europe Bv |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and immune checkpoint inhibitors
|
|
WO2024137776A1
(en)
|
2022-12-21 |
2024-06-27 |
Bristol-Myers Squibb Company |
Combination therapy for lung cancer
|
|
WO2024137865A1
(en)
|
2022-12-22 |
2024-06-27 |
Gossamer Bio Services, Inc. |
Compounds useful as t cell activators
|
|
WO2024150017A1
(en)
|
2023-01-13 |
2024-07-18 |
Akrivia Biomedics Limited |
Method of profiling diseases
|
|
WO2024163477A1
(en)
|
2023-01-31 |
2024-08-08 |
University Of Rochester |
Immune checkpoint blockade therapy for treating staphylococcus aureus infections
|
|
US20240299601A1
(en)
|
2023-02-17 |
2024-09-12 |
Regeneron Pharmaceuticals, Inc. |
Radiolabeled anti-lag3 antibodies for immuno-pet imaging
|
|
WO2024192033A1
(en)
|
2023-03-13 |
2024-09-19 |
Regeneron Pharmaceuticals, Inc. |
Combination of pd-1 inhibitors and lag-3 inhibitors for enhanced efficacy in treating melanoma
|
|
WO2024196952A1
(en)
|
2023-03-20 |
2024-09-26 |
Bristol-Myers Squibb Company |
Tumor subtype assessment for cancer therapy
|
|
WO2024200823A1
(en)
|
2023-03-30 |
2024-10-03 |
Ose Immunotherapeutics |
Lipid-based nanoparticle targeted at activated immune cells for the expression of immune cell enhancing molecule and use thereof
|
|
WO2024200826A1
(en)
|
2023-03-30 |
2024-10-03 |
Ose Immunotherapeutics |
Lipid-based nanoparticle targeted at activated immune cells for the expression of immune cell inhibiting molecule and use thereof
|
|
US20240425497A1
(en)
|
2023-05-05 |
2024-12-26 |
Arcus Biosciences, Inc. |
Cbl-b Inhibitors and Methods of Use Thereof
|
|
WO2024233514A1
(en)
|
2023-05-08 |
2024-11-14 |
Bristol-Myers Squibb Company |
Substituted phenyl oxazolone compounds
|
|
WO2024233900A1
(en)
|
2023-05-10 |
2024-11-14 |
Blueprint Medicines Corporation |
Gsk3a inhibitors and methods of use thereof
|
|
WO2024243502A1
(en)
|
2023-05-25 |
2024-11-28 |
Arcus Biosciences, Inc. |
Cbl-b inhibitors and methods of use thereof
|
|
WO2024249894A2
(en)
|
2023-06-02 |
2024-12-05 |
Arcus Biosciences, Inc. |
Biomarkers for predicting cancer treatment efficacy
|
|
WO2024254227A1
(en)
|
2023-06-07 |
2024-12-12 |
Bristol-Myers Squibb Company |
Spirocyclic substituted oxoisoindolinyl piperidine-2,6-dione compound
|
|
WO2024263853A1
(en)
|
2023-06-23 |
2024-12-26 |
Bristol-Myers Squibb Company |
Substituted oxoisoindolinyl piperidine-2,6-dione compound as anticancer agent
|
|
US20240425607A1
(en)
|
2023-06-26 |
2024-12-26 |
Compugen Ltd. |
Il-18bp antagonist antibodies and their use in monotherapy and combination therapy in the treatment of cancer
|
|
WO2025006799A1
(en)
|
2023-06-27 |
2025-01-02 |
Capstan Therapeutics, Inc. |
Extracorporeal and ex vivo engineering of select cell populations from peripheral blood
|
|
WO2025030002A2
(en)
|
2023-08-02 |
2025-02-06 |
Arvinas Operations, Inc. |
Dgk targeting compounds and uses thereof
|