SG10201601719RA - Anti-LAG-3 Antibodies - Google Patents
Anti-LAG-3 AntibodiesInfo
- Publication number
- SG10201601719RA SG10201601719RA SG10201601719RA SG10201601719RA SG10201601719RA SG 10201601719R A SG10201601719R A SG 10201601719RA SG 10201601719R A SG10201601719R A SG 10201601719RA SG 10201601719R A SG10201601719R A SG 10201601719RA SG 10201601719R A SG10201601719R A SG 10201601719RA
- Authority
- SG
- Singapore
- Prior art keywords
- lag
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2812—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SG10201601719RA SG10201601719RA (en) | 2016-03-04 | 2016-03-04 | Anti-LAG-3 Antibodies |
| EP17710682.0A EP3423492A1 (en) | 2016-03-04 | 2017-03-03 | Anti-lag-3 antibodies |
| AU2017226965A AU2017226965A1 (en) | 2016-03-04 | 2017-03-03 | Anti-LAG-3antibodies |
| US16/079,947 US20190040136A1 (en) | 2016-03-04 | 2017-03-03 | Anti-lag-3 antibodies |
| SG11201807252QA SG11201807252QA (en) | 2016-03-04 | 2017-03-03 | Anti-lag-3 antibodies |
| KR1020187028534A KR20180114218A (en) | 2016-03-04 | 2017-03-03 | Anti-LAG-3 antibody |
| TW106107003A TW201734042A (en) | 2016-03-04 | 2017-03-03 | Anti-LAG-3 antibodies |
| JP2018546454A JP2019517773A (en) | 2016-03-04 | 2017-03-03 | Anti-LAG-3 antibody |
| CN201780015245.3A CN109219619A (en) | 2016-03-04 | 2017-03-03 | anti-LAG-3 antibody |
| PCT/EP2017/055060 WO2017149143A1 (en) | 2016-03-04 | 2017-03-03 | Anti-lag-3 antibodies |
| CA3015938A CA3015938A1 (en) | 2016-03-04 | 2017-03-03 | Anti-lag-3 antibodies |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SG10201601719RA SG10201601719RA (en) | 2016-03-04 | 2016-03-04 | Anti-LAG-3 Antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201601719RA true SG10201601719RA (en) | 2017-10-30 |
Family
ID=58277259
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201601719RA SG10201601719RA (en) | 2016-03-04 | 2016-03-04 | Anti-LAG-3 Antibodies |
| SG11201807252QA SG11201807252QA (en) | 2016-03-04 | 2017-03-03 | Anti-lag-3 antibodies |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201807252QA SG11201807252QA (en) | 2016-03-04 | 2017-03-03 | Anti-lag-3 antibodies |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20190040136A1 (en) |
| EP (1) | EP3423492A1 (en) |
| JP (1) | JP2019517773A (en) |
| KR (1) | KR20180114218A (en) |
| CN (1) | CN109219619A (en) |
| AU (1) | AU2017226965A1 (en) |
| CA (1) | CA3015938A1 (en) |
| SG (2) | SG10201601719RA (en) |
| TW (1) | TW201734042A (en) |
| WO (1) | WO2017149143A1 (en) |
Families Citing this family (67)
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| TWI756187B (en) | 2015-10-09 | 2022-03-01 | 美商再生元醫藥公司 | Anti-lag3 antibodies and uses thereof |
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| MA47456A (en) | 2017-02-10 | 2019-12-18 | Regeneron Pharma | RADIO-LABELED ANTI-LAG3 ANTIBODIES FOR IMMUNO-PET IMAGING |
| IL322104A (en) | 2017-05-30 | 2025-09-01 | Bristol Myers Squibb Co | Treatment of tumors that express LAG–3 |
| MX2019012038A (en) | 2017-05-30 | 2019-11-18 | Bristol Myers Squibb Co | Compositions comprising a combination of an anti-lag-3 antibody, a pd-1 pathway inhibitor, and an immunotherapeutic agent. |
| AU2018275209A1 (en) | 2017-05-30 | 2019-10-17 | Bristol-Myers Squibb Company | Compositions comprising an anti-LAG-3 antibody or an anti-LAG-3 antibody and an anti-PD-1 or anti-PD-L1 antibody |
| CN118373912A (en) | 2017-11-10 | 2024-07-23 | 新加坡科技研究局 | IL2 Rbeta/common gamma chain antibodies |
| WO2019179365A1 (en) * | 2018-03-20 | 2019-09-26 | WuXi Biologics Ireland Limited | Novel anti-lag-3 antibody polypeptide |
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| EP2958942B1 (en) | 2013-02-20 | 2020-06-03 | Novartis AG | Effective targeting of primary human leukemia using anti-cd123 chimeric antigen receptor engineered t cells |
| ES2808654T3 (en) * | 2013-03-15 | 2021-03-01 | Glaxosmithkline Ip Dev Ltd | Anti-LAG-3 binding proteins |
| US9790282B2 (en) | 2013-03-25 | 2017-10-17 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anti-CD276 polypeptides, proteins, and chimeric antigen receptors |
| PT3508502T (en) | 2013-09-20 | 2023-06-22 | Bristol Myers Squibb Co | Combination of anti-lag-3 antibodies and anti-pd-1 antibodies to treat tumors |
| SI3712174T1 (en) | 2013-12-24 | 2022-06-30 | Janssen Pharmaceutica Nv | VISTA antibodies and particles |
-
2016
- 2016-03-04 SG SG10201601719RA patent/SG10201601719RA/en unknown
-
2017
- 2017-03-03 TW TW106107003A patent/TW201734042A/en unknown
- 2017-03-03 US US16/079,947 patent/US20190040136A1/en not_active Abandoned
- 2017-03-03 EP EP17710682.0A patent/EP3423492A1/en not_active Withdrawn
- 2017-03-03 KR KR1020187028534A patent/KR20180114218A/en not_active Withdrawn
- 2017-03-03 JP JP2018546454A patent/JP2019517773A/en active Pending
- 2017-03-03 CA CA3015938A patent/CA3015938A1/en not_active Abandoned
- 2017-03-03 CN CN201780015245.3A patent/CN109219619A/en active Pending
- 2017-03-03 AU AU2017226965A patent/AU2017226965A1/en not_active Abandoned
- 2017-03-03 SG SG11201807252QA patent/SG11201807252QA/en unknown
- 2017-03-03 WO PCT/EP2017/055060 patent/WO2017149143A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| TW201734042A (en) | 2017-10-01 |
| KR20180114218A (en) | 2018-10-17 |
| EP3423492A1 (en) | 2019-01-09 |
| US20190040136A1 (en) | 2019-02-07 |
| JP2019517773A (en) | 2019-06-27 |
| CA3015938A1 (en) | 2017-09-08 |
| SG11201807252QA (en) | 2018-09-27 |
| WO2017149143A1 (en) | 2017-09-08 |
| AU2017226965A1 (en) | 2018-10-11 |
| CN109219619A (en) | 2019-01-15 |
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