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PE20160999A1 - Metodos para administrar anticuerpos anti-tnf-alfa - Google Patents

Metodos para administrar anticuerpos anti-tnf-alfa

Info

Publication number
PE20160999A1
PE20160999A1 PE2016001292A PE2016001292A PE20160999A1 PE 20160999 A1 PE20160999 A1 PE 20160999A1 PE 2016001292 A PE2016001292 A PE 2016001292A PE 2016001292 A PE2016001292 A PE 2016001292A PE 20160999 A1 PE20160999 A1 PE 20160999A1
Authority
PE
Peru
Prior art keywords
seq
tnf
dosage forms
alpha antibody
methods
Prior art date
Application number
PE2016001292A
Other languages
English (en)
Inventor
Joachim Kempeni
Roberta Weiss
Steven Fischkoff
Original Assignee
Abbvie Biotechnology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23144283&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20160999(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbvie Biotechnology Ltd filed Critical Abbvie Biotechnology Ltd
Publication of PE20160999A1 publication Critical patent/PE20160999A1/es

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Abstract

Se refiere a formas de dosificacion subcutanea que comprenden 40 mg de un anticuerpo anti–TNF–alfa humano, dicho anticuerpo se caracteriza porque comprende: a) una region variable de cadena liviana (LCVR) cuyos dominios CDR3, CDR2 y CDR1 comprenden secuencias de aminoacidos de SEQ ID NO: 3, SEQ ID NO: 5 y SEQ ID NO: 7, respectivamente; b) una region variable de cadena pesada (HCVR) cuyos dominios CDR3, CDR2 y CDR1 comprenden secuencias de aminoacidos de SEQ ID NO: 4, SEQ ID NO: 6 y SEQ ID NO: 8, respectivamente; y al menos un vehiculo farmaceuticamente aceptable. En un aspecto, la forma de dosificacion subcutanea es una jeringa precargada que comprende dicho anticuerpo anti–TNF–alfa. En un aspecto preferido, el anticuerpo anti–TNF–alfa es D2E7. Opcionalmente, dichas formas de dosificacion comprenden un agente terapeutico adicional, preferentemente metotrexato. Tambien se refiere a kits que comprenden dichas formas de dosificacion subcutanea
PE2016001292A 2001-06-08 2002-06-07 Metodos para administrar anticuerpos anti-tnf-alfa PE20160999A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29696101P 2001-06-08 2001-06-08

Publications (1)

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PE20160999A1 true PE20160999A1 (es) 2016-10-08

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ID=23144283

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