[go: up one dir, main page]

NO20050923L - Mikronalanordninger og mikronalleveringsnordning - Google Patents

Mikronalanordninger og mikronalleveringsnordning

Info

Publication number
NO20050923L
NO20050923L NO20050923A NO20050923A NO20050923L NO 20050923 L NO20050923 L NO 20050923L NO 20050923 A NO20050923 A NO 20050923A NO 20050923 A NO20050923 A NO 20050923A NO 20050923 L NO20050923 L NO 20050923L
Authority
NO
Norway
Prior art keywords
micronal
devices
microneedles
supply
feeling
Prior art date
Application number
NO20050923A
Other languages
English (en)
Inventor
Michael D Delmore
Michael K Domroese
Richard H Ferber
Jay D Jacobs
Graham M Clarke
Jamieson C Keister
Frank Frederickson
Original Assignee
3M Innovative Properties Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Innovative Properties Co filed Critical 3M Innovative Properties Co
Publication of NO20050923L publication Critical patent/NO20050923L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0244—Micromachined materials, e.g. made from silicon wafers, microelectromechanical systems [MEMS] or comprising nanotechnology

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Mikronålanordninger (10) og mikronåler (30) som har en avkortet konisk form er beskrevet. Mikronålene av mikronålanordningene kan også ha et styrt aspekt- forhold. Mikronålleveranseanordning er beskrevet som inkluderer drivere designet til å levere mikronåler ved hastigheter som kan forbedre perforering av sfratum comeum mens de samtidig begrenser følelsen av smerte opplevd på leveringsstedet.
NO20050923A 2002-07-19 2005-02-21 Mikronalanordninger og mikronalleveringsnordning NO20050923L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39737202P 2002-07-19 2002-07-19
US42477402P 2002-11-08 2002-11-08
PCT/US2003/021538 WO2004009172A1 (en) 2002-07-19 2003-07-10 Microneedle devices and microneedle delivery apparatus

Publications (1)

Publication Number Publication Date
NO20050923L true NO20050923L (no) 2005-02-21

Family

ID=30773016

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20050923A NO20050923L (no) 2002-07-19 2005-02-21 Mikronalanordninger og mikronalleveringsnordning

Country Status (13)

Country Link
US (1) US8900194B2 (no)
EP (1) EP1523367A1 (no)
JP (2) JP2005533625A (no)
KR (2) KR101323980B1 (no)
CN (2) CN102872526A (no)
AU (1) AU2003251831B2 (no)
BR (1) BR0312671A (no)
CA (1) CA2492867C (no)
IL (1) IL166134A0 (no)
MX (1) MXPA05000597A (no)
NO (1) NO20050923L (no)
NZ (1) NZ537546A (no)
WO (1) WO2004009172A1 (no)

Families Citing this family (162)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7419481B2 (en) * 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
AU2003209645A1 (en) * 2002-03-04 2003-09-16 Nano Pass Technologies Ltd. Devices and methods for transporting fluid across a biological barrier
CN102872526A (zh) 2002-07-19 2013-01-16 3M创新有限公司 微针装置和微针施用设备
JP2007503268A (ja) 2003-08-25 2007-02-22 スリーエム イノベイティブ プロパティズ カンパニー 免疫応答修飾化合物の送達
EP1680154B1 (en) * 2003-10-31 2012-01-04 ALZA Corporation Self-actuating applicator for microprojection array
EP1706171A1 (en) * 2003-12-29 2006-10-04 3M Innovative Properties Company Medical devices and kits including same
EP1718452A1 (en) * 2004-02-23 2006-11-08 3M Innovative Properties Company Method of molding for microneedle arrays
WO2006018642A1 (en) 2004-08-16 2006-02-23 Functional Microstructures Limited Method of producing a microneedle or microimplant
US8057842B2 (en) 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
CN101060883B (zh) * 2004-11-18 2010-06-23 3M创新有限公司 低轮廓微针阵列施放器
JP5015787B2 (ja) 2004-11-18 2012-08-29 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイの接触コーティング法
US9174035B2 (en) 2004-11-18 2015-11-03 3M Innovative Properties Company Microneedle array applicator and retainer
CN101102809B (zh) * 2004-11-18 2010-05-26 3M创新有限公司 涂敷微针阵列的遮蔽方法
AU2012201016B2 (en) * 2004-11-18 2012-10-11 3M Innovative Properties Company Low-profile microneedle array applicator
CN102358015A (zh) * 2004-12-07 2012-02-22 3M创新有限公司 模制微型针的方法
WO2006062848A1 (en) * 2004-12-10 2006-06-15 3M Innovative Properties Company Medical device
WO2006101459A1 (en) * 2005-03-23 2006-09-28 Agency For Science, Technology And Research Microneedles
US8280476B2 (en) 2005-03-29 2012-10-02 Arkal Medical, Inc. Devices, systems, methods and tools for continuous glucose monitoring
WO2006108185A1 (en) 2005-04-07 2006-10-12 3M Innovative Properties Company System and method for tool feedback sensing
WO2007002523A2 (en) 2005-06-24 2007-01-04 3M Innovative Properties Company Collapsible patch with microneedle array
CN101208129B (zh) * 2005-06-27 2011-03-30 3M创新有限公司 微针药筒组件及其施放方法
EP2474338B1 (en) * 2005-06-27 2013-07-24 3M Innovative Properties Company Microneedle array applicator device
CA2614927A1 (en) * 2005-07-25 2007-02-01 Nanotechnology Victoria Pty Ltd Microarray device
JP5000866B2 (ja) * 2005-08-01 2012-08-15 久光製薬株式会社 生体無毒性医薬物運搬用器具
CN101912288A (zh) * 2005-09-02 2010-12-15 因特赛尔美国公司 经皮递送疫苗和透皮递送药物的装置及其应用
JP2007089792A (ja) * 2005-09-28 2007-04-12 Nano Device & System Research Inc 経皮投与装置
JP2007130417A (ja) * 2005-11-08 2007-05-31 Nano Device & System Research Inc 経皮投与装置
WO2007061781A1 (en) 2005-11-18 2007-05-31 3M Innovative Properties Company Coatable compositions, coatings derived therefrom and microarrays having such coatings
US20080262416A1 (en) * 2005-11-18 2008-10-23 Duan Daniel C Microneedle Arrays and Methods of Preparing Same
US8554317B2 (en) * 2005-11-30 2013-10-08 3M Innovative Properties Company Microneedle arrays and methods of use thereof
EP1800622A1 (en) * 2005-12-23 2007-06-27 SDI Surgical Device International GmbH Spring-biased injector for an intraocular lens
US7658728B2 (en) * 2006-01-10 2010-02-09 Yuzhakov Vadim V Microneedle array, patch, and applicator for transdermal drug delivery
US7699819B2 (en) 2006-02-21 2010-04-20 The Hong Kong University Of Science And Technology Molecular sieve and zeolite microneedles and preparation thereof
EP1998844A4 (en) * 2006-03-24 2017-03-01 3M Innovative Properties Company Process for making microneedles, microneedle arrays, masters, and replication tools
US9119945B2 (en) 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
US20070276330A1 (en) * 2006-05-28 2007-11-29 Beck Patricia A Microneedles and methods of fabricating thereof
EP2041214A4 (en) 2006-07-10 2009-07-08 Medipacs Inc SUPERELASTIC EPOXY HYDROGEL
US20080058726A1 (en) * 2006-08-30 2008-03-06 Arvind Jina Methods and Apparatus Incorporating a Surface Penetration Device
US7785301B2 (en) * 2006-11-28 2010-08-31 Vadim V Yuzhakov Tissue conforming microneedle array and patch for transdermal drug delivery or biological fluid collection
US20080214987A1 (en) * 2006-12-22 2008-09-04 Nanomed Devices, Inc. Microdevice And Method For Transdermal Delivery And Sampling Of Active Substances
US8911749B2 (en) 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
EP2146689B1 (en) 2007-04-16 2020-08-12 Corium, Inc. Solvent-cast microneedle arrays containing active
JP5173332B2 (ja) * 2007-09-10 2013-04-03 凸版印刷株式会社 マイクロニードルおよびマイクロニードル製造方法
ES2612061T3 (es) * 2007-09-28 2017-05-11 The Queen's University Of Belfast Dispositivo y método de suministro
WO2009073734A2 (en) 2007-12-03 2009-06-11 Medipacs, Inc. Fluid metering device
EP2280645B1 (en) 2008-05-02 2015-03-18 Covidien LP Skin preparation device and biopotential sensor
EP2296731A2 (en) * 2008-06-06 2011-03-23 Wockhardt Research Centre A device and a system for delivery of biological material
WO2010022326A2 (en) * 2008-08-22 2010-02-25 Us Worldmeds Llc Transdermal delivery of apomorphine using microneedles
CN101342404B (zh) * 2008-08-28 2010-04-14 上海交通大学 用于透皮给药的异平面金属空心微针制作方法
ES2643606T3 (es) * 2008-11-18 2017-11-23 3M Innovative Properties Company Matriz de microagujas huecas
CN101829396B (zh) * 2009-03-27 2013-01-30 清华大学 微针阵列芯片及利用其的经皮给药贴剂及其制备方法
US20110009782A1 (en) * 2009-07-07 2011-01-13 Naya Touch, Inc. Dermal roller with therapeutic microstructures
CN101618250B (zh) * 2009-07-31 2013-06-05 清华大学 基于微针阵列柔性芯片的经皮给药贴片及其制备方法
US9238102B2 (en) 2009-09-10 2016-01-19 Medipacs, Inc. Low profile actuator and improved method of caregiver controlled administration of therapeutics
CN101670611B (zh) * 2009-10-15 2012-06-13 上海交通大学 用于制备透皮微针阵列的石膏模具的制备方法
US9500186B2 (en) 2010-02-01 2016-11-22 Medipacs, Inc. High surface area polymer actuator with gas mitigating components
US8911422B2 (en) 2010-02-24 2014-12-16 Hisamitsu Pharmaceutical Co., Inc. Micro-needle device
US9687641B2 (en) 2010-05-04 2017-06-27 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
JP5797644B2 (ja) * 2010-05-28 2015-10-21 久光製薬株式会社 微小突起付きアレイ
US9693950B2 (en) 2010-05-28 2017-07-04 3M Innovative Properties Company Aqueous formulations for coating microneedle arrays
JP5885667B2 (ja) * 2010-10-07 2016-03-15 久光製薬株式会社 アプリケータ
US20120089118A1 (en) * 2010-10-08 2012-04-12 A Nevada Corporation Delivery of bisphosphonates by microinjection systems
WO2012061556A1 (en) 2010-11-03 2012-05-10 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
JP2012100783A (ja) * 2010-11-08 2012-05-31 Nanbu Plastics Co Ltd 薬液供給装置
EP2646218B1 (en) * 2010-12-02 2016-04-06 3M Innovative Properties Company Liquid crystalline polymer microneedles
WO2012075339A1 (en) * 2010-12-02 2012-06-07 Lanco Biosciences, Inc. Delivery of heparins by microinjection systems
WO2012074721A2 (en) * 2010-12-02 2012-06-07 Lanco Biosciences, Inc. Delivery of serotonin receptor antagonists by microinjection systems
IT1403293B1 (it) 2010-12-27 2013-10-17 Fond Don Carlo Gnocchi Onlus Apparecchiatura ad aghi per la somministrazione transdermica di farmaci.
US20140066842A1 (en) 2011-03-07 2014-03-06 3M Innovative Properties Company Microneedle devices and methods
WO2012122163A1 (en) 2011-03-07 2012-09-13 3M Innovative Properties Company Microneedle devices and methods
CN102805896A (zh) * 2011-05-30 2012-12-05 惠觅宙 经皮给药方法、制剂和系统
CN103687643B (zh) * 2011-07-27 2016-04-20 久光制药株式会社 施放器
WO2013038890A1 (ja) * 2011-09-16 2013-03-21 久光製薬株式会社 アプリケータ
EP2764887B1 (en) 2011-10-06 2020-12-02 Hisamitsu Pharmaceutical Co., Inc. Applicator
KR20140074383A (ko) * 2011-10-12 2014-06-17 쓰리엠 이노베이티브 프로퍼티즈 컴파니 통합형 마이크로니들 어레이 전달 시스템
EP2766066B8 (en) 2011-10-12 2021-01-20 Kindeva Drug Delivery L.P. Integrated microneedle array delivery system
JP2013090837A (ja) * 2011-10-26 2013-05-16 Toppan Printing Co Ltd 針状体の製造方法および針状体
CN104080441B (zh) 2011-11-30 2020-02-28 3M创新有限公司 包括肽治疗剂和氨基酸的微针装置、制备和使用其的方法
EP2790684B1 (en) 2011-12-16 2016-10-12 3M Innovative Properties Company Foldable adhesive composite dressing
EP2793869B1 (en) 2011-12-21 2015-09-23 3M Innovative Properties Company Transdermal adhesive patch assembly with removable microneedle array and method of using same
CA2906274A1 (en) 2012-03-14 2013-09-19 Medipacs, Inc. Smart polymer materials with excess reactive molecules
JP6226862B2 (ja) * 2012-04-05 2017-11-08 久光製薬株式会社 穿刺装置及びその製造方法
WO2014047429A1 (en) 2012-09-21 2014-03-27 3M Innovative Properties Company Incision protection
EP2906285B1 (en) 2012-10-10 2019-06-12 3M Innovative Properties Company Applicator for applying a microneedle device to skin
EP2906284B8 (en) 2012-10-10 2021-01-20 Kindeva Drug Delivery L.P. Force-controlled applicator for applying a microneedle device to skin
WO2014062538A1 (en) 2012-10-19 2014-04-24 3M Innovative Properties Company Polysaccharide-containing hydrogels, compositions, articles, and methods
KR102187985B1 (ko) * 2012-11-09 2020-12-07 도판 인사츠 가부시키가이샤 바늘 형상 구조체 및 그 제조 방법
US9789299B2 (en) 2012-11-16 2017-10-17 3M Innovative Properties Company Force-controlled applicator for applying a microneedle device to skin
MX375307B (es) 2012-12-21 2025-03-06 Corium Inc Microarreglo para la entrega de agente terapeutico y metodos de uso.
CN104884119B (zh) 2012-12-27 2018-04-20 3M创新有限公司 具有中空微针的制品及其制备方法
CN104902943B (zh) 2013-01-08 2017-10-31 3M创新有限公司 用于向皮肤施用微针装置的施用装置
WO2014132240A1 (en) * 2013-02-28 2014-09-04 Kimberly-Clark Worldwide, Inc. Transdermal drug delivery device
AU2014249471B2 (en) * 2013-03-12 2019-01-24 Corium Pharma Solutions, Inc. Microprojection applicators
ES2908339T3 (es) 2013-03-15 2022-04-28 Corium Inc Micromatriz para el suministro de un agente terapéutico y métodos de uso
AU2014237357B2 (en) 2013-03-15 2019-11-28 Corium Pharma Solutions, Inc. Multiple impact microprojection applicators and methods of use
US9962534B2 (en) 2013-03-15 2018-05-08 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
CA2903763C (en) 2013-03-15 2021-11-16 Corium International, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
US20160271380A1 (en) 2013-03-22 2016-09-22 3M Innovative Properties Company Microneedle applicator comprising a counter assembly
US9750533B2 (en) * 2013-04-12 2017-09-05 L'oreal Exfoliating head for a personal care appliance
JP6494602B2 (ja) 2013-05-31 2019-04-03 スリーエム イノベイティブ プロパティズ カンパニー 二重カバーを備えるマイクロニードル注射装置
KR102274902B1 (ko) 2013-05-31 2021-07-07 쓰리엠 이노베이티브 프로퍼티즈 컴파니 마이크로니들 주사 및 주입 장치 및 그의 사용 방법
PL3003459T3 (pl) * 2013-05-31 2018-11-30 3M Innovative Properties Company Mikroigłowy aparat iniekcyjny zawierający odwrócony element wykonawczy
EP3021929B1 (en) 2013-07-16 2020-02-26 3M Innovative Properties Company Hollow microneedle with bevel opening
WO2015009530A1 (en) 2013-07-16 2015-01-22 3M Innovative Properties Company Hollow microneedle array article
EP3021932B1 (en) 2013-07-16 2021-03-24 Kindeva Drug Delivery L.P. Article comprising a microneedle
US10232157B2 (en) 2013-07-16 2019-03-19 3M Innovative Properties Company Hollow microneedle with beveled tip
EP3047871B1 (en) * 2013-09-18 2018-05-02 Cosmed Pharmaceutical Co., Ltd. Microneedle patch application device and patch holder
JP6199702B2 (ja) * 2013-11-06 2017-09-20 久光製薬株式会社 アプリケータ
EP3117867B1 (en) * 2014-03-12 2019-07-24 Labo Juversa Co., Ltd. Micro-needle preparation administration member for intradermal placement of target substance and apparatus for rapid administration of micro-needle preparation
KR101736021B1 (ko) * 2014-04-30 2017-05-15 킴벌리-클라크 월드와이드, 인크. 경피적 약물 전달 장치 및 방법의 제어기 부분
US10624843B2 (en) 2014-09-04 2020-04-21 Corium, Inc. Microstructure array, methods of making, and methods of use
WO2016118459A1 (en) 2015-01-21 2016-07-28 3M Innovative Properties Company Microneedle array and method of use
WO2016122915A1 (en) 2015-01-27 2016-08-04 3M Innovative Properties Company Alum-containing coating formulations for microneedle vaccine patches
WO2016172554A1 (en) * 2015-04-23 2016-10-27 Carnegie Mellon University Biosensor tattoos and uses therefor for biomarker monitoring
CN108135177B (zh) 2015-04-29 2021-06-01 雷迪厄斯制药公司 用于治疗癌症的方法
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
KR102135518B1 (ko) 2015-09-02 2020-07-17 히사미쓰 세이야꾸 가부시키가이샤 어플리케이터
CA2999538A1 (en) * 2015-09-28 2017-04-06 Vaxxas Pty Limited Microprojection arrays with enhanced skin penetrating properties and methods thereof
JP7116680B2 (ja) 2015-10-09 2022-08-10 キンデーバ ドラッグ デリバリー リミティド パートナーシップ コーティングされたマイクロニードルアレイのための亜鉛組成物
WO2017151806A1 (en) 2016-03-01 2017-09-08 Kitotech Medical, Inc. Microstructure-based systems, apparatus, and methods for wound closure
ES2904891T3 (es) 2016-04-18 2022-04-06 Radius Health Inc Formulaciones de abaloparatida, parche transdérmico de la misma y usos de la misma
WO2017198872A1 (en) 2016-05-20 2017-11-23 Uprax System and method for applying microneedles
US9629991B1 (en) 2016-06-08 2017-04-25 Eclipse Aesthetics, LLC Disposable radio frequency needle cartridges having absorbing containment barriers
US10220195B2 (en) 2016-06-08 2019-03-05 Eclipse Medcorp, Llc Radio frequency needling device for use with disposable needle cartridges
US9636491B1 (en) 2016-06-08 2017-05-02 Eclipse Aesthetics, LLC Disposable needle cartridges having absorbing contaminant barriers
CN107569238A (zh) * 2016-07-04 2018-01-12 中山大学 一种粘贴式烟囱型微针阵列及其制造方法
WO2018056584A1 (ko) 2016-09-21 2018-03-29 삼성전자 주식회사 피부 상태 측정 방법 및 이를 위한 전자 장치
JP6644666B2 (ja) * 2016-10-18 2020-02-12 富士フイルム株式会社 マイクロニードルアレイ穿刺用デバイスおよびマイクロニードルアレイ穿刺用セット
EP3560545B1 (en) * 2016-12-20 2021-05-26 Hisamitsu Pharmaceutical Co., Inc. Applicator
JP6629713B2 (ja) * 2016-12-27 2020-01-15 久光製薬株式会社 アプリケータおよび穿刺キット
CN110191707A (zh) 2017-01-05 2019-08-30 雷迪厄斯制药公司 Rad1901-2hcl的多晶型形式
WO2018129499A1 (en) 2017-01-09 2018-07-12 Verily Life Sciences Llc Systems and methods for wearable emergency drug injection devices
CN106806986B (zh) * 2017-03-27 2023-12-29 深圳市纬安共创生物科技有限公司 一种可调档位的微针种植手具
JP6931217B2 (ja) 2017-03-28 2021-09-01 コスメディ製薬株式会社 水溶性シート状製剤のアプリケータ
CN115923337A (zh) 2017-03-31 2023-04-07 瓦克萨斯私人有限公司 用于涂覆表面的设备和方法
BR112019023985A2 (pt) * 2017-05-17 2020-06-09 Massachusetts Inst Technology sistema de autocorreção e componentes e métodos relacionados
US11541015B2 (en) 2017-05-17 2023-01-03 Massachusetts Institute Of Technology Self-righting systems, methods, and related components
IL273926B2 (en) 2017-10-17 2024-06-01 3M Innovative Properties Company Conductor for applying a micro-needle array to the skin
JP2019097656A (ja) * 2017-11-29 2019-06-24 Ａｓｔｉ株式会社 マイクロニードル穿刺装置
EP3744374A4 (en) 2018-01-24 2021-11-03 Cosmed Pharmaceutical Co., Ltd. FASTENING DEVICE FOR MICRON NEEDLE
CN112996550B (zh) * 2018-05-01 2023-02-28 Csp技术公司 药物输送设备及其使用和制造方法
EP3793440A1 (en) 2018-05-16 2021-03-24 Kindeva Drug Delivery L.P. Microneedle biosensor
WO2019222570A1 (en) 2018-05-17 2019-11-21 Massachusetts Institute Of Technology Systems for electrical stimulation
US11460411B2 (en) 2018-06-18 2022-10-04 Kindeva Drug Delivery L.P. Process and apparatus for inspecting microneedle arrays
SG11202013177WA (en) 2018-07-04 2021-01-28 Radius Pharmaceuticals Inc Polymorphic forms of rad 1901-2hcl
JP7491551B2 (ja) 2019-04-25 2024-05-28 コスメディ製薬株式会社 水溶性シート状製剤のアプリケータ２
CN110772376A (zh) * 2019-11-20 2020-02-11 韩熠 一种用于婴幼儿及儿童的医用眼贴及其制备方法
WO2021168345A1 (en) 2020-02-19 2021-08-26 Kitotech Medical, Inc. Microstructure systems and methods for pain treatment
AU2021265743A1 (en) 2020-04-28 2022-11-03 Ticona Llc Microneedle assembly
US12053284B2 (en) 2021-11-08 2024-08-06 Satio, Inc. Dermal patch for collecting a physiological sample
US12029562B2 (en) 2021-04-14 2024-07-09 Satio, Inc. Dermal patch system
US12214346B2 (en) 2021-10-13 2025-02-04 Satio, Inc. Dermal patch with a diagnostic test strip
US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample
US11964121B2 (en) 2021-10-13 2024-04-23 Satio, Inc. Mono dose dermal patch for pharmaceutical delivery
US12048543B2 (en) 2021-11-08 2024-07-30 Satio, Inc. Dermal patch for collecting a physiological sample with removable vial
US12023156B2 (en) 2021-10-13 2024-07-02 Satio, Inc. Dermal patch for collecting a physiological sample
US12178979B2 (en) 2021-10-13 2024-12-31 Satio, Inc. Dermal patch for delivering a pharmaceutical
DE102021130950A1 (de) * 2021-11-25 2023-05-25 Lts Lohmann Therapie-Systeme Ag. Applikationshilfe
WO2023159181A1 (en) 2022-02-18 2023-08-24 Kitotech Medical, Inc. Force modulating deep skin staples and instruments
WO2024097385A1 (en) 2022-11-05 2024-05-10 Kindeva Drug Delivery L.P. Microneedle array applicator and system
WO2024129424A1 (en) 2022-12-16 2024-06-20 Kindeva Drug Delivery L.P. Drug delivery device
KR102729228B1 (ko) * 2024-04-18 2024-11-13 주식회사에이치앤디테크 친환경적 마이크로 니들 어플리케이터

Family Cites Families (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3123212A (en) 1964-03-03 Multiple disposable intracutaneous injector package
US2619962A (en) 1948-02-19 1952-12-02 Res Foundation Vaccination appliance
US3072122A (en) 1959-01-15 1963-01-08 Rosenthal Sol Roy Package for transcutaneous injection
US3034507A (en) 1960-05-10 1962-05-15 American Cyanamid Co Intracutaneous injection device
US3074403A (en) 1960-05-17 1963-01-22 American Cyanamid Co Intracutaneous injector with capillary gap
US3136314A (en) 1960-08-01 1964-06-09 Kravitz Harvey Vaccinating devices
US3246647A (en) 1962-07-23 1966-04-19 American Cyanamid Co Disposable intracutaneous injector
US3221740A (en) 1962-08-31 1965-12-07 Rosenthal Sol Roy Injection device
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US3678150A (en) 1971-07-27 1972-07-18 American Cyanamid Co Process for improving the stability of ppd, qt and histoplasmin on tine applicators
DE2250293A1 (de) 1972-10-13 1974-04-25 Bayern Freistaat Impfstempel zur cutanen pockenimpfung mittels trockenimpfstoff
US4018938A (en) 1975-06-30 1977-04-19 International Business Machines Corporation Fabrication of high aspect ratio masks
US4165395A (en) 1977-06-30 1979-08-21 International Business Machines Corporation Process for forming a high aspect ratio structure by successive exposures with electron beam and actinic radiation
US4304241A (en) 1978-09-05 1981-12-08 Aller-Screen, Inc. Skin testing device
US4237906A (en) 1978-12-06 1980-12-09 Havstad Harold R Antigen injection assembly
JPS5590931A (en) 1978-12-29 1980-07-10 Canon Inc Production of micro structure element array
US4568632A (en) 1982-10-07 1986-02-04 International Business Machines Corporation Patterning of polyimide films with far ultraviolet light
US4508749A (en) 1983-12-27 1985-04-02 International Business Machines Corporation Patterning of polyimide films with ultraviolet light
US4822975A (en) 1984-01-30 1989-04-18 Canon Kabushiki Kaisha Method and apparatus for scanning exposure
DE3517729A1 (de) 1985-05-17 1986-11-20 Kernforschungszentrum Karlsruhe Gmbh, 7500 Karlsruhe Verfahren zum herstellen von spinnduesenplatten
US4768358A (en) * 1986-08-04 1988-09-06 Robert Viola Security handle lock
US4786358A (en) 1986-08-08 1988-11-22 Semiconductor Energy Laboratory Co., Ltd. Method for forming a pattern of a film on a substrate with a laser beam
JPH01245993A (ja) 1988-03-27 1989-10-02 Semiconductor Energy Lab Co Ltd 薄膜加工装置
GB2221394B (en) 1988-08-05 1992-03-04 Eilert Eilertsen An injection device
DE3842354A1 (de) 1988-12-16 1990-06-21 Kernforschungsz Karlsruhe Verfahren zur lithographischen herstellung von galvanisch abformbaren mikrostrukturen mit dreieckigem oder trapezfoermigem querschnitt
DE3842610C1 (no) 1988-12-17 1990-06-21 Kernforschungszentrum Karlsruhe Gmbh, 7500 Karlsruhe, De
CA2016900A1 (en) 1989-07-06 1991-01-06 Ronald J. Filipski Tines structure in clinical applicator
US5262128A (en) 1989-10-23 1993-11-16 The United States Of America As Represented By The Department Of Health And Human Services Array-type multiple cell injector
EP0429842B1 (en) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
US6090790A (en) 1989-12-14 2000-07-18 Eriksson; Elof Gene delivery by microneedle injection
DE4010669C1 (no) 1990-04-03 1991-04-11 Kernforschungszentrum Karlsruhe Gmbh, 7500 Karlsruhe, De
US5389954A (en) 1990-11-21 1995-02-14 Canon Kabushiki Kaisha Laser process apparatus for forming holes in a workpiece
US5279544A (en) 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
US5160823A (en) 1991-01-03 1992-11-03 Hutchinson Technology, Inc. Moving mask laser imaging
US5342737A (en) 1992-04-27 1994-08-30 The United States Of America As Represented By The Secretary Of The Navy High aspect ratio metal microstructures and method for preparing the same
DE4222856C1 (no) 1992-07-11 1993-05-27 Buerkert Gmbh
JP3211525B2 (ja) 1993-04-22 2001-09-25 オムロン株式会社 薄材メッシュ、その製造方法及びその製造装置
US5457041A (en) 1994-03-25 1995-10-10 Science Applications International Corporation Needle array and method of introducing biological substances into living cells using the needle array
FR2720003B1 (fr) 1994-05-23 1998-06-26 Samsung Electro Mech Dispositif servant à inciser la peau pour une médication transcutanée.
JPH10507844A (ja) 1994-09-09 1998-07-28 ボード オブ スーパーバイザーズ オブ ルイジアナ ステート ユニバーシティ アンド アグリカルチュラル アンド メカニカル カレッジ マイクロ構造体及びその製造方法
CA2201315A1 (en) * 1994-09-30 1996-04-11 Peter Ping Ling Direct introduction of foreign materials into cells
WO1996033839A1 (en) 1995-04-26 1996-10-31 Minnesota Mining And Manufacturing Company Method and apparatus for step and repeat exposures
AU5869796A (en) 1995-05-22 1996-12-11 Ned A. Godshall Micromechanical patch for enhancing the delivery of compound s through the skin
AU5740496A (en) 1995-05-22 1996-12-11 General Hospital Corporation, The Micromechanical device and method for enhancing delivery of compounds through the skin
DE19525607A1 (de) 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
US5658515A (en) 1995-09-25 1997-08-19 Lee; Abraham P. Polymer micromold and fabrication process
US5657516A (en) 1995-10-12 1997-08-19 Minnesota Mining And Manufacturing Company Dual structured fastener elements
AU3399197A (en) * 1996-06-18 1998-01-07 Alza Corporation Device for enhancing transdermal agent delivery or sampling
CA2259437C (en) 1996-07-03 2006-12-05 Altea Technologies, Inc. Multiple mechanical microporation of skin or mucosa
WO1998011937A1 (en) 1996-09-17 1998-03-26 Deka Products Limited Partnership System for delivery of drugs by transport
US6797276B1 (en) 1996-11-14 2004-09-28 The United States Of America As Represented By The Secretary Of The Army Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response
US6605332B2 (en) 1997-07-29 2003-08-12 3M Innovative Properties Company Unitary polymer substrate having napped surface of frayed end microfibers
ATE221400T1 (de) 1997-12-11 2002-08-15 Alza Corp Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
DE69839969D1 (de) 1997-12-11 2008-10-16 Alza Corp Vorrichtung zur verbesserung des transdermalen flusses von medikamenten
WO1999064580A1 (en) 1998-06-10 1999-12-16 Georgia Tech Research Corporation Microneedle devices and methods of manufacture and use thereof
US6503231B1 (en) 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
GB9815819D0 (en) 1998-07-22 1998-09-16 Secr Defence Transferring materials into cells and a microneedle array
GB9815820D0 (en) 1998-07-22 1998-09-16 Secr Defence Improvements relating to micro-machining
GB9817662D0 (en) * 1998-08-13 1998-10-07 Crocker Peter J Substance delivery
JP2002523195A (ja) 1998-08-31 2002-07-30 ジョンソン・アンド・ジョンソン・コンシューマー・カンパニーズ・インコーポレイテッド ブレードを備える電子輸送装置
US6713291B2 (en) 1999-01-28 2004-03-30 Alan D. King Electrodes coated with treating agent and uses thereof
WO2000044438A1 (en) 1999-01-28 2000-08-03 Cyto Pulse Sciences, Inc. Delivery of macromolecules into cells
US6743211B1 (en) 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
EP1187653B1 (en) 1999-06-04 2010-03-31 Georgia Tech Research Corporation Devices for enhanced microneedle penetration of biological barriers
US6312612B1 (en) 1999-06-09 2001-11-06 The Procter & Gamble Company Apparatus and method for manufacturing an intracutaneous microneedle array
US6379324B1 (en) 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
US6256533B1 (en) 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6623457B1 (en) 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance
US6835184B1 (en) * 1999-09-24 2004-12-28 Becton, Dickinson And Company Method and device for abrading skin
US6331266B1 (en) 1999-09-29 2001-12-18 Becton Dickinson And Company Process of making a molded device
US20020095134A1 (en) 1999-10-14 2002-07-18 Pettis Ronald J. Method for altering drug pharmacokinetics based on medical delivery platform
WO2001033614A1 (en) 1999-11-02 2001-05-10 University Of Hawaii Method for fabricating arrays of micro-needles
MXPA02004863A (es) 1999-11-15 2003-01-28 Velcro Ind Miembro de sujecion dermica.
US6595947B1 (en) 2000-05-22 2003-07-22 Becton, Dickinson And Company Topical delivery of vaccines
US6565532B1 (en) 2000-07-12 2003-05-20 The Procter & Gamble Company Microneedle apparatus used for marking skin and for dispensing semi-permanent subcutaneous makeup
AU2001265056A1 (en) * 2000-05-26 2001-12-11 The Procter And Gamble Company Microneedle apparatus used for marking skin and for dispensing semi-permanent subcutaneous makeup
US7473244B2 (en) 2000-06-02 2009-01-06 The University Of Utah Research Foundation Active needle devices with integrated functionality
GB0017999D0 (en) 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
US6759110B1 (en) * 2000-08-15 2004-07-06 3M Innovative Properties Company Structured release liners with improved adhesion to adhesive articles
US6533949B1 (en) 2000-08-28 2003-03-18 Nanopass Ltd. Microneedle structure and production method therefor
AU9682801A (en) * 2000-10-13 2002-04-22 Alza Corp Apparatus and method for piercing skin with microprotrusions
US7131987B2 (en) 2000-10-16 2006-11-07 Corium International, Inc. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation
US7108681B2 (en) * 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin
WO2002055128A2 (en) 2000-11-30 2002-07-18 Biovalve Technologies Inc Fluid delivery and measurement systems and methods
EP1345646A2 (en) 2000-12-14 2003-09-24 Georgia Tech Research Corporation Microneedle devices and production thereof
AU2002231207A1 (en) 2000-12-21 2002-07-01 Biovalve Technologies, Inc. Microneedle array systems
US6663820B2 (en) 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
US6591124B2 (en) 2001-05-11 2003-07-08 The Procter & Gamble Company Portable interstitial fluid monitoring system
WO2002100466A2 (en) 2001-06-08 2002-12-19 The Regents Of The University Of California Microfabricated surgical devices and methods of making the same
US6686299B2 (en) 2001-06-21 2004-02-03 Carlo D. Montemagno Nanosyringe array and method
CN1253220C (zh) 2001-06-29 2006-04-26 贝克顿迪肯森公司 通过微管在真皮内输入疫苗和基因治疗剂
US6881203B2 (en) 2001-09-05 2005-04-19 3M Innovative Properties Company Microneedle arrays and methods of manufacturing the same
AU2002327675A1 (en) * 2001-09-19 2003-04-01 Biovalve Technologies, Inc. Microneedles, microneedle arrays, and systems and methods relating to same
EP1469903A2 (en) * 2001-09-28 2004-10-27 BioValve Technologies, Inc. Microneedle with membrane
US20030093040A1 (en) 2001-10-29 2003-05-15 Mikszta John A. Method and device for the delivery of a substance
AU2002360361A1 (en) 2001-11-09 2003-06-10 Biomicroarrays, Inc. High surface area substrates for microarrays and methods to make same
EP1485317A2 (en) 2001-11-30 2004-12-15 Alza Corporation Methods and apparatuses for forming microprojection arrays
ES2297056T3 (es) 2001-12-20 2008-05-01 Alza Corporation Micro-proyecciones para perforacion de la piel que tienen control de la profundidad de perforacion.
US6908453B2 (en) 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
US20040060902A1 (en) 2002-02-05 2004-04-01 Evans John D. Microprotrusion array and methods of making a microprotrusion
US6899838B2 (en) 2002-07-12 2005-05-31 Becton, Dickinson And Company Method of forming a mold and molding a micro-device
CN102872526A (zh) 2002-07-19 2013-01-16 3M创新有限公司 微针装置和微针施用设备
ES2537171T3 (es) 2002-08-29 2015-06-03 Becton Dickinson And Company Micro-raspador con características de raspado controladas
US20040106904A1 (en) 2002-10-07 2004-06-03 Gonnelli Robert R. Microneedle array patch
WO2005000382A2 (en) 2003-06-04 2005-01-06 Georgia Tech Research Corporation Drilling microneedle device
AU2004253571A1 (en) 2003-07-02 2005-01-13 Alza Corporation Microprojection array immunization patch and method
BRPI0413354A (pt) 2003-08-04 2006-10-10 Alza Corp método e dispositivo para intensificar fluxo de agente transdérmico
CN1842355A (zh) 2003-08-26 2006-10-04 阿尔扎公司 用于皮内细胞植入的装置和方法
US8353861B2 (en) 2003-09-18 2013-01-15 Texmac, Inc. Applicator for applying functional substances into human skin
AU2004285484A1 (en) 2003-10-24 2005-05-12 Alza Corporation Pretreatment method and system for enhancing transdermal drug delivery
EP1686904A4 (en) 2003-11-21 2008-02-27 Alza Corp ULTRASONICALLY SUPPORTED TRANSDERMAL VACCINE METHOD AND SYSTEM
KR100781702B1 (ko) 2006-07-21 2007-12-03 연세대학교 산학협력단 중공형 마이크로니들 및 이의 제조방법

Also Published As

Publication number Publication date
MXPA05000597A (es) 2005-04-28
CN102872526A (zh) 2013-01-16
CA2492867A1 (en) 2004-01-29
AU2003251831A1 (en) 2004-02-09
US20050261631A1 (en) 2005-11-24
KR101323980B1 (ko) 2013-10-30
KR20050019898A (ko) 2005-03-03
EP1523367A1 (en) 2005-04-20
JP2005533625A (ja) 2005-11-10
AU2003251831B2 (en) 2009-06-11
KR20120087197A (ko) 2012-08-06
IL166134A0 (en) 2006-01-15
JP2011147807A (ja) 2011-08-04
AU2003251831A2 (en) 2004-02-09
BR0312671A (pt) 2005-04-26
NZ537546A (en) 2007-04-27
JP5336538B2 (ja) 2013-11-06
CN1691969A (zh) 2005-11-02
CA2492867C (en) 2011-07-05
US8900194B2 (en) 2014-12-02
WO2004009172A1 (en) 2004-01-29

Similar Documents

Publication Publication Date Title
NO20050923L (no) Mikronalanordninger og mikronalleveringsnordning
CN102413853B (zh) 能够控制流体输送的微针单元
WO2003024518A3 (en) Microstructures for delivering a composition cutaneously to skin using rotatable structures
DE60106261D1 (de) Abgabevorrichtung mit mikronadeln zur transdermalen verabreichung von einer substanz
WO2002085447A3 (en) Microprojection array having a beneficial agent containing coating
ATE384549T1 (de) Mikronadel-vorrichtungen und verfahren zur herstellung
DE60213976D1 (de) Vorrichtung zur manipulation von nadeln oder polierarray
MXPA03003815A (es) Dispositivos de suministro transdermico de farmaco que tienen microrresaltos recubiertos.
ATE500860T1 (de) System aus insertionskopf und inserter
WO2003057286A1 (fr) Instrument d'administration a usage medical
DK1267980T3 (da) Kateter til nerveblokade
ATE450234T1 (de) Tränenpunktpfropf
US10166171B2 (en) Acupuncture device and needle wakening method
JP2006296924A (ja) 鍼灸針
KR20160095576A (ko) 자운고를 이용한 마이크로니들 어레이 및 이의 패치
AU2002368333A1 (en) Device transforming the pain of a syringe needle into a tolerable feeling
JP2007037707A (ja) 皮膚用針
WO2002085279A8 (en) Self-stimulating clogs for performing a zonal therapy with changeable stimulation points
KR102085434B1 (ko) 피부용 초음파 인젝터
JP3144390U (ja) 針灸ツボ絆創膏
KR200391458Y1 (ko) 한방용 침 세트
UA51776C2 (uk) Пристрій для масажу "аромоіплікатор"
KR200396484Y1 (ko) 자석안마기
CN2476278Y (zh) 自助式保健治疗结构体
KR20190127235A (ko) 미용액의 전달성이 향상된 니들 패치

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application