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MX9600666A - Proteinas de protocadherina y su uso. - Google Patents

Proteinas de protocadherina y su uso.

Info

Publication number
MX9600666A
MX9600666A MX9600666A MX9600666A MX9600666A MX 9600666 A MX9600666 A MX 9600666A MX 9600666 A MX9600666 A MX 9600666A MX 9600666 A MX9600666 A MX 9600666A MX 9600666 A MX9600666 A MX 9600666A
Authority
MX
Mexico
Prior art keywords
protocadherins
protocadherin
proteins
protocadherin proteins
polypeptides
Prior art date
Application number
MX9600666A
Other languages
English (en)
Inventor
Shintaro Suzuki
Original Assignee
Doheny Eye Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Doheny Eye Inst filed Critical Doheny Eye Inst
Publication of MX9600666A publication Critical patent/MX9600666A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Las secuencias de polinucleotido que codifican los polipeptidos semejantes a cadherina, designados, protocadherinas y las variantes de los mismos, se proporcionan mediante la invencion, así como los métodos y materiales para la produccion recombinante de los mismos. Las sustancias de anticuerpo específicas para protocadherina se dan también a conocer como utiles para modular las actividades naturales de ligazon y/o regulatorias de las protocadherinas.
MX9600666A 1994-06-27 1995-06-26 Proteinas de protocadherina y su uso. MX9600666A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/268,161 US5798224A (en) 1992-12-29 1994-06-27 Nucleic acids encoding protocadherin
PCT/US1995/008071 WO1996000289A1 (en) 1994-06-27 1995-06-26 Protocadherin proteins and their uses

Publications (1)

Publication Number Publication Date
MX9600666A true MX9600666A (es) 1997-06-28

Family

ID=23021746

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9600666A MX9600666A (es) 1994-06-27 1995-06-26 Proteinas de protocadherina y su uso.

Country Status (18)

Country Link
US (5) US5798224A (es)
EP (1) EP0719330B1 (es)
JP (1) JP3560344B2 (es)
CN (1) CN1105187C (es)
AT (1) ATE309347T1 (es)
AU (1) AU699135B2 (es)
BR (1) BR9506058A (es)
CA (1) CA2170156A1 (es)
CZ (1) CZ288789B6 (es)
DE (1) DE69534588D1 (es)
FI (1) FI960888A0 (es)
HU (1) HU221637B1 (es)
MX (1) MX9600666A (es)
NO (1) NO319686B1 (es)
PL (1) PL182324B1 (es)
RU (1) RU2197525C2 (es)
SK (1) SK281413B6 (es)
WO (1) WO1996000289A1 (es)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458939B1 (en) 1996-03-15 2002-10-01 Millennium Pharmaceuticals, Inc. Compositions and methods for the diagnosis, prevention, and treatment of neoplastic cell growth and proliferation
WO1998030584A2 (en) * 1997-01-09 1998-07-16 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
US20020137890A1 (en) * 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
AU3908299A (en) * 1997-12-08 1999-06-28 Ontogeny, Inc. Cadherin-like polypeptides, methods and compositions related thereto
EP2256204A1 (en) * 1997-12-10 2010-12-01 CSL Limited Porphorymonas gingivalis polypeptides and polynucleotides
DK1241185T3 (da) * 1998-03-26 2005-04-25 Genentech Inc Nucleinsyrer, der er opformeret i humane tumorer, samt beslægtede materialer og fremgangsmåder
US7481999B2 (en) * 1998-05-05 2009-01-27 Adherex Technologies, Inc. Compounds and methods for modulating OB-cadherin-mediated function
US6680175B2 (en) * 1998-05-05 2004-01-20 Adherex Technologies, Inc. Methods for diagnosing and evaluating cancer
US6472367B1 (en) 1998-05-05 2002-10-29 Adherex Technologies, Inc. Compounds and methods for modulating OB-cadherin mediated cell adhesion
US6638911B1 (en) 1998-05-05 2003-10-28 Adherex Technologies Inc. Compounds and methods for modulating desmosomal cadherin-mediated functions
US20050203025A1 (en) * 1998-05-05 2005-09-15 Adherex Technologies, Inc. Compounds and methods for modulating nonclassical cadherin-mediated functions
US6277824B1 (en) 1998-07-10 2001-08-21 Adherex Technologies Compounds and methods for modulating adhesion molecule function
US20030096951A1 (en) * 1998-08-14 2003-05-22 Kenneth Jacobs Secreted proteins and polynucleotides encoding them
US7041807B1 (en) 1999-06-23 2006-05-09 Caprion Pharmaceuticals, Inc. Antibodies to a YYX epitope of a mammalian prion protein
US6787136B1 (en) 1999-09-03 2004-09-07 The Brigham And Women's Hospital, Inc. Methods and compositions for treatment of inflammatory disease using cadherin-11 modulating agents
US7193050B2 (en) 2000-02-18 2007-03-20 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
CN1313328A (zh) * 2000-03-15 2001-09-19 上海博德基因开发有限公司 一种新的多肽——人原钙粘素14和编码这种多肽的多核苷酸
AU2001275306A1 (en) * 2000-06-06 2001-12-17 Genaissance Pharmaceuticals, Inc. Haplotypes of the pcdh2 gene
US6790636B1 (en) * 2000-06-14 2004-09-14 The United States Of America As Represented By The Department Of Health And Human Services Rapid fluorescent labeling of tissue for microdissection using fluorescent specific binding agents
JP2004504018A (ja) * 2000-07-19 2004-02-12 ファルマシア・アンド・アップジョン・カンパニー β−セレクターゼ活性の基質およびアッセイ
US7122311B2 (en) * 2001-07-16 2006-10-17 Novartis Ag Methods for determining the risk of developing asthma characterized by bronchial hyperresponsiveness
US20040072236A1 (en) 2002-09-27 2004-04-15 Neil Cashman PrPSc -interacting molecules and uses thereof
WO2004048411A2 (en) * 2002-11-14 2004-06-10 Adherex Technologies, Inc. Compounds and methods for modulating desmosomal and atypical cadherin-mediated cell adhesion
CN101492673B (zh) * 2008-01-25 2012-01-11 中国科学院上海生命科学研究院 非洲爪蟾xpapc基因启动子及其组织特异性增强子
CN102274506A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 治疗或预防癌症的药物
CN102274509A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 治疗或预防癌症的药物
CN102274503A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 治疗或预防癌症的药物
CN102274490A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 一种用于治疗或预防癌症的药物
CN102274501A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 一种治疗或预防癌症的药物
CN102274489A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 治疗或预防癌症的药物
CN102274507A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 一种用于治疗或预防癌症的药物
CN102274499A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 用于治疗或预防癌症的药物
MA33276B1 (fr) * 2009-04-20 2012-05-02 Oxford Biotherapeutics Ltd Anticorps spécifiques à la cadhérine-17
WO2011115268A1 (ja) * 2010-03-18 2011-09-22 大日本住友製薬株式会社 腫瘍血管新生阻害剤
US8877188B2 (en) 2010-05-04 2014-11-04 The Brigham And Women's Hospital, Inc. Detection and treatment of non-dermal fibrosis
US9534058B2 (en) 2012-02-08 2017-01-03 Abbvie Stemcentrx Llc Anti-CD324 monoclonal antibodies and uses thereof
CN103194476A (zh) * 2013-04-07 2013-07-10 新乡医学院 鸡pcdh1基因部分片段的克隆、表达及多克隆抗体的制备
AU2015302959B2 (en) * 2014-08-12 2018-09-20 Novartis Ag Anti-CDH6 antibody drug conjugates
US11097005B2 (en) 2014-12-15 2021-08-24 The Brigham And Women's Hospital, Inc. Use of cadherin-11 antagonists to treat metabolic disorders and/or increase insulin sensitivity

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05500504A (ja) * 1989-09-27 1993-02-04 アテナ・ニュウロサイエンスィズ・インコーポレイテッド 細胞付着阻止のための組成物及び使用方法
DE69129760T2 (de) * 1990-10-30 1999-03-25 La Jolla Cancer Research Foundation, La Jolla, Calif. T-cadherin-bindungsmolekül

Also Published As

Publication number Publication date
FI960888L (fi) 1996-02-26
SK25296A3 (en) 1997-02-05
NO960767L (no) 1996-04-26
US6262237B1 (en) 2001-07-17
HUT75825A (en) 1997-05-28
HU9600449D0 (en) 1996-04-29
WO1996000289A1 (en) 1996-01-04
CN1105187C (zh) 2003-04-09
NO319686B1 (no) 2005-09-05
AU2872495A (en) 1996-01-19
HU221637B1 (hu) 2002-12-28
US5798224A (en) 1998-08-25
EP0719330A1 (en) 1996-07-03
DE69534588D1 (de) 2005-12-15
PL182324B1 (pl) 2001-12-31
CA2170156A1 (en) 1996-01-04
SK281413B6 (sk) 2001-03-12
CN1134172A (zh) 1996-10-23
US5708143A (en) 1998-01-13
JPH09505740A (ja) 1997-06-10
CZ288789B6 (cs) 2001-09-12
EP0719330B1 (en) 2005-11-09
JP3560344B2 (ja) 2004-09-02
CZ48296A3 (en) 1996-11-13
PL313256A1 (en) 1996-06-24
BR9506058A (pt) 1997-08-05
RU2197525C2 (ru) 2003-01-27
US5891706A (en) 1999-04-06
AU699135B2 (en) 1998-11-26
US20030139581A1 (en) 2003-07-24
NO960767D0 (no) 1996-02-26
ATE309347T1 (de) 2005-11-15
FI960888A0 (fi) 1996-02-26

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