DE60006163D1 - Verfahren zur herstellung von 5-cyanophthalid - Google Patents

Verfahren zur herstellung von 5-cyanophthalid

Info

Publication number: DE60006163D1
Authority: DE; Germany
Prior art keywords: sup; sub; cyanophthalide; preparation; alkyl
Prior art date: 2000-01-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE60006163T

Other languages

English (en)

Other versions

DE60006163T2 (de

Inventor

Hans Petersen

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

H Lundbeck AS

Original Assignee

H Lundbeck AS

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-14

Filing date

2000-01-14

Publication date

2003-11-27

2000-01-14 Application filed by H Lundbeck AS filed Critical H Lundbeck AS

2003-11-27 Application granted granted Critical

2003-11-27 Publication of DE60006163D1 publication Critical patent/DE60006163D1/de

2004-04-15 Publication of DE60006163T2 publication Critical patent/DE60006163T2/de

2020-01-15 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/10—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Plural Heterocyclic Compounds (AREA)
Cephalosporin Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Furan Compounds (AREA)

DE60006163T 2000-01-14 2000-01-14 Verfahren zur herstellung von 5-cyanophthalid Expired - Fee Related DE60006163T2 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/DK2000/000016 WO2001051477A1 (en)	2000-01-14	2000-01-14	Method for the preparation of 5-cyanophthalide

Publications (2)

Publication Number	Publication Date
DE60006163D1 true DE60006163D1 (de)	2003-11-27
DE60006163T2 DE60006163T2 (de)	2004-04-15

Family

ID=8149377

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60006163T Expired - Fee Related DE60006163T2 (de)	2000-01-14	2000-01-14	Verfahren zur herstellung von 5-cyanophthalid

Country Status (27)

Country	Link
US (1)	US6911548B2 (de)
EP (1)	EP1254129B1 (de)
JP (1)	JP2003519691A (de)
KR (1)	KR100660802B1 (de)
CN (1)	CN1195749C (de)
AT (1)	ATE252570T1 (de)
AU (1)	AU3033700A (de)
CA (1)	CA2397270C (de)
CZ (1)	CZ20022601A3 (de)
DE (1)	DE60006163T2 (de)
DK (1)	DK1254129T3 (de)
EA (1)	EA005134B1 (de)
ES (1)	ES2206177T3 (de)
HK (1)	HK1054392B (de)
HU (1)	HUP0300343A2 (de)
IL (2)	IL150561A0 (de)
IS (1)	IS2168B (de)
IT (1)	ITMI20010040A1 (de)
MX (1)	MXPA02006915A (de)
NO (1)	NO20023405L (de)
PL (1)	PL197821B1 (de)
PT (1)	PT1254129E (de)
SI (1)	SI1254129T1 (de)
SK (1)	SK286879B6 (de)
TR (1)	TR200201783T2 (de)
UA (1)	UA72569C2 (de)
WO (1)	WO2001051477A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2291129C (en) *	1999-04-14	2002-10-22	H. Lundbeck A/S	Method for the preparation of citalopram
CA2395404A1 (en)	1999-12-28	2001-07-05	H. Lundbeck A/S	Method for the preparation of citalopram
DK1246813T3 (da)	1999-12-30	2004-03-01	Lundbeck & Co As H	Fremgangsmåde til fremstilling af Citalopram
HUP0300343A2 (hu)	2000-01-14	2003-06-28	H. Lundbeck A/S	Eljárás 5-cianoftalid előállítására
NL1017417C1 (nl)	2000-03-03	2001-03-16	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
GB0005477D0 (en)	2000-03-07	2000-04-26	Resolution Chemicals Limited	Process for the preparation of citalopram
KR20020080481A (ko)	2000-03-13	2002-10-23	하. 룬트벡 아크티에 셀스카브	시탈로프람의 제조 방법
IES20010206A2 (en)	2000-03-13	2002-03-06	Lundbeck & Co As H	Method for the preparation of citalopram
JP2003527385A (ja)	2000-03-13	2003-09-16	ハー・ルンドベック・アクチエゼルスカベット	５−置換された１−（４−フルオロフェニル）−１，３−ジヒドロイソベンゾフランの段階的アルキル化法
AU2001239213A1 (en)	2000-03-14	2001-09-24	H Lundbeck A/S	Method for the preparation of citalopram
AR032455A1 (es)	2000-05-12	2003-11-12	Lundbeck & Co As H	Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
WO2003097622A2 (en) *	2002-05-15	2003-11-27	Genzyme Corporation	Synthesis of 2-alkylcysteines, 2-(hydroxylated phenyl)-4-alkylthiazoline-4-carboxylic acids and derivatives thereof
WO2005111010A1 (en) *	2004-05-13	2005-11-24	Suven Life Sciences Ltd,	An improved process for the preparation of 5-cyanophthalide
CN116022748B (zh) *	2022-12-16	2024-02-27	山东惟普新能源有限公司	一种含水双氟磺酰亚胺锂的除水方法

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1143702A (de) *	1965-03-18
GB1526331A (en) *	1976-01-14	1978-09-27	Kefalas As	Phthalanes
GB8419963D0 (en) *	1984-08-06	1984-09-12	Lundbeck & Co As H	Intermediate compound and method
GB8814057D0 (en) *	1988-06-14	1988-07-20	Lundbeck & Co As H	New enantiomers & their isolation
US5296507A (en) *	1990-09-06	1994-03-22	H.Lundbeck A/S	Treatment of cerbrovascular disorders
DE19626659A1 (de) *	1996-07-03	1998-01-08	Basf Ag	Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) *	1996-07-10	1998-01-15	Basf Ag	Verfahren zur Herstellung von Phthaliden
ES2148120T3 (es)	1997-07-08	2002-01-16	Lundbeck & Co As H	Metodo para la preparacion de citalopram.
UA62985C2 (en)	1997-11-10	2004-01-15	Lunnbeck As H	A method for the preparation of citalopram
TR200001341T2 (tr)	1997-11-11	2000-11-21	H. Lundbeck A/S	Sitalopramın hazırlandığı metot
JP3892667B2 (ja)	1998-10-20	2007-03-14	ハー・ルンドベック・アクチエゼルスカベット	シタロプラムの製造方法
SK285530B6 (sk)	1998-12-23	2007-03-01	H. Lundbeck A/S	Spôsob prípravy 5-kyanoftalidu
AR022329A1 (es) *	1999-01-29	2002-09-04	Lundbeck & Co As H	Metodo para la preparacion de 5-cianoftalida
CA2291129C (en) *	1999-04-14	2002-10-22	H. Lundbeck A/S	Method for the preparation of citalopram
ITMI991581A1 (it) *	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991579A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
TR200101874T1 (tr)	1999-10-25	2002-02-21	H. Lundbeck A/S	Sitalopram hazırlanması için yöntem
AR026063A1 (es) *	1999-11-01	2002-12-26	Lundbeck & Co As H	Metodo para la preparacion de 5-carboxiftalida.
US6310222B1 (en)	1999-11-01	2001-10-30	Sumika Fine Chemicals Co., Ltd.	Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
CA2395404A1 (en)	1999-12-28	2001-07-05	H. Lundbeck A/S	Method for the preparation of citalopram
DK1246813T3 (da)	1999-12-30	2004-03-01	Lundbeck & Co As H	Fremgangsmåde til fremstilling af Citalopram
HUP0300343A2 (hu)	2000-01-14	2003-06-28	H. Lundbeck A/S	Eljárás 5-cianoftalid előállítására
FR2805812A1 (fr) *	2000-02-24	2001-09-07	Lundbeck & Co As H	Procede de preparation du citalopram
IES20010143A2 (en) *	2000-02-24	2001-07-25	Lundbeck & Co As H	Method for the preparation of citalopram
GB0005477D0 (en)	2000-03-07	2000-04-26	Resolution Chemicals Limited	Process for the preparation of citalopram
FI20011622L (fi) *	2000-08-18	2002-02-19	Lundbeck & Co As H	Menetelmä sitalopraamin valmistamiseksi
BR0106272A (pt)	2000-12-22	2004-06-15	Lundbeck & Co As H	Processo para preparação de citalopram puro
DK1181272T3 (da)	2000-12-28	2002-12-30	Lundbeck & Co As H	Fremgangsmåde til fremstilling af rent citalopram

2000
- 2000-01-14 HU HU0300343A patent/HUP0300343A2/hu unknown
- 2000-01-14 MX MXPA02006915A patent/MXPA02006915A/es active IP Right Grant
- 2000-01-14 EA EA200200758A patent/EA005134B1/ru not_active IP Right Cessation
- 2000-01-14 JP JP2001551859A patent/JP2003519691A/ja not_active Withdrawn
- 2000-01-14 PL PL356712A patent/PL197821B1/pl not_active IP Right Cessation
- 2000-01-14 KR KR1020027008951A patent/KR100660802B1/ko not_active Expired - Fee Related
- 2000-01-14 SK SK1166-2002A patent/SK286879B6/sk not_active IP Right Cessation
- 2000-01-14 CA CA002397270A patent/CA2397270C/en not_active Expired - Fee Related
- 2000-01-14 IL IL15056100A patent/IL150561A0/xx active IP Right Grant
- 2000-01-14 TR TR2002/01783T patent/TR200201783T2/xx unknown
- 2000-01-14 EP EP00900501A patent/EP1254129B1/de not_active Expired - Lifetime
- 2000-01-14 DE DE60006163T patent/DE60006163T2/de not_active Expired - Fee Related
- 2000-01-14 AT AT00900501T patent/ATE252570T1/de not_active IP Right Cessation
- 2000-01-14 WO PCT/DK2000/000016 patent/WO2001051477A1/en active IP Right Grant
- 2000-01-14 SI SI200030247T patent/SI1254129T1/xx unknown
- 2000-01-14 CN CNB008183759A patent/CN1195749C/zh not_active Expired - Fee Related
- 2000-01-14 ES ES00900501T patent/ES2206177T3/es not_active Expired - Lifetime
- 2000-01-14 CZ CZ20022601A patent/CZ20022601A3/cs unknown
- 2000-01-14 UA UA2002075750A patent/UA72569C2/uk unknown
- 2000-01-14 AU AU30337/00A patent/AU3033700A/en not_active Abandoned
- 2000-01-14 DK DK00900501T patent/DK1254129T3/da active
- 2000-01-14 PT PT00900501T patent/PT1254129E/pt unknown
2001
- 2001-01-11 IT IT2001MI000040A patent/ITMI20010040A1/it unknown
2002
- 2002-06-28 IS IS6449A patent/IS2168B/is unknown
- 2002-07-03 IL IL150561A patent/IL150561A/en not_active IP Right Cessation
- 2002-07-08 US US10/191,808 patent/US6911548B2/en not_active Expired - Fee Related
- 2002-07-15 NO NO20023405A patent/NO20023405L/no not_active Application Discontinuation
2003
- 2003-09-19 HK HK03106740.7A patent/HK1054392B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
HK1054392A1 (en)	2003-11-28
NO20023405D0 (no)	2002-07-15
ES2206177T3 (es)	2004-05-16
CZ20022601A3 (cs)	2002-10-16
CA2397270C (en)	2007-08-21
IS2168B (is)	2006-11-15
DK1254129T3 (da)	2004-03-29
ITMI20010040A1 (it)	2002-07-11
PL197821B1 (pl)	2008-04-30
CN1195749C (zh)	2005-04-06
AU3033700A (en)	2001-07-24
HUP0300343A2 (hu)	2003-06-28
NO20023405L (no)	2002-08-30
CN1423643A (zh)	2003-06-11
PT1254129E (pt)	2004-03-31
US6911548B2 (en)	2005-06-28
HK1054392B (zh)	2005-11-18
EP1254129B1 (de)	2003-10-22
DE60006163T2 (de)	2004-04-15
ATE252570T1 (de)	2003-11-15
IL150561A (en)	2007-07-04
MXPA02006915A (es)	2002-10-23
SK286879B6 (sk)	2009-07-06
IL150561A0 (en)	2003-02-12
KR20020073501A (ko)	2002-09-26
PL356712A1 (en)	2004-06-28
EP1254129A1 (de)	2002-11-06
JP2003519691A (ja)	2003-06-24
UA72569C2 (uk)	2005-03-15
TR200201783T2 (tr)	2002-12-23
IS6449A (is)	2002-06-28
SI1254129T1 (en)	2004-02-29
EA005134B1 (ru)	2004-12-30
US20030013895A1 (en)	2003-01-16
WO2001051477A1 (en)	2001-07-19
EA200200758A1 (ru)	2002-12-26
CA2397270A1 (en)	2001-07-19
KR100660802B1 (ko)	2006-12-26
SK11662002A3 (sk)	2003-01-09

Publication	Publication Date	Title
BG105457A (en)	2001-12-29	Method for the preparation of citalopram
DE60006163D1 (de)	2003-11-27	Verfahren zur herstellung von 5-cyanophthalid
EA199900301A2 (ru)	1999-10-28	Замещенные трициклические соединения
KR970027031A (ko)	1997-06-24	일차 또는 이차 알콜의 산화방법
EA200500037A1 (ru)	2005-06-30	Фенилбензамиды
EA200000431A3 (ru)	2001-02-26	Новые замещенные димерные соединения, способ их получения и фармацевтические композиции, содержащие их
EA200100297A1 (ru)	2001-08-27	Моногидрат гидробромида элетриптана
DE69908909D1 (de)	2003-07-24	Verfahren zur herstellung von simvastatin und ihren derivaten
DE60101786D1 (de)	2004-02-19	Verfahren zur herstellung von citalopram
DE502004002562D1 (de)	2007-02-15	Verfahren zur herstellung hochreiner polyalkylenglykole
GT199900047A (es)	2000-09-15	Procedimiento para alquilar sulfonamidas impedidas estèricamente.
MXPA04003086A (es)	2004-09-06	Proceso para sintesis estereoselectiva de 2-hidroximetil-cromanos.
DE60204014D1 (de)	2005-06-09	Chlormethylierung von thiophene
ATE249450T1 (de)	2003-09-15	Verfahren zur herstellung von l-ascorbinsäure
ATE363460T1 (de)	2007-06-15	Verfahren zur herstellung von fluorhalogenalkanen
ATE210114T1 (de)	2001-12-15	Herstellung von di-tert-peroxiden
HUP0300845A2 (hu)	2003-07-28	Sebgyógyulást elősegítő készítmény, eljárás az előállítására és alkalmazása
ATE307794T1 (de)	2005-11-15	Verfahren zur herstellung von chlorcarbonsäurechloriden
BR0017002A (pt)	2002-10-15	Método para a preparação de 5-cianoftalida
ES2190610T3 (es)	2003-08-01	Sintesis de 3-carbometoxi-4,5-dimetiltiofeno.
ATE238283T1 (de)	2003-05-15	Verbessertes verfahren zur herstellung von 2- halogenpyridin-n-oxid
JPS5583778A (en)	1980-06-24	Large-ring oxalkyl lactone having side chain and its preparation
ATE260267T1 (de)	2004-03-15	Verfahren zur herstellung von c-4-deacetyltaxanen
ATE272618T1 (de)	2004-08-15	Verfahren zur herstellung von s-alkylcysteinen
MXPA03005556A (es)	2004-05-31	Derivados de 1,1-dioxo-1,2-benzotiacina-3-carboxamidas, metodo para prepararlos y composiciones farmaceuticas que los contienen.

Legal Events

Date	Code	Title	Description
2004-11-18	8364	No opposition during term of opposition
2010-11-18	8339	Ceased/non-payment of the annual fee