CN102907456A - Pesticide combination containing ZJ3757 and profenofos - Google Patents

Abstract

The invention provides an agricultural insecticide composition, which contains two active components, the first active component is o-formamidobenzamide insecticide ZJ3757, and the second active component is profenofos , the weight ratio of the first active component to the second active component is 1:50˜6:1. The agricultural insecticide composition of the invention has significant synergistic effect, and is especially suitable for controlling Lepidoptera rice leaf roller and cotton bollworm.

Description

Insecticidal composition containing ZJ3757 and profenofos

technical field

The invention belongs to the field of agricultural pesticides.

Background technique

Cnaphalocrocis medinalis, Chilo suppressalis and Tryporyza incertulas are the main pests of rice production safety. There are more than 200 species of host plants of cotton bollworm (Helicoverpa armigera), which occur in cotton and vegetable growing areas of China. Cotton areas in the Yellow River Basin and the Yangtze River Basin were severely affected. It is particularly important to screen out new pesticides that can effectively control rice leaf rollers, rice stem borers, rice stem borers and cotton bollworms

ZJ3757 belongs to o-formamidobenzamide insecticides and is a compound developed by our company. Its chemical structure is as follows:

The chemical name is: N-(2-(tert-butylcarbamoyl)-4-chloro-6-methylphenyl)-1-(3-chloropyridin-2-yl)-3-fluoromethoxy-1H-pyridine Azole-5-carboxamide, molecular formula: C ₂₂ H ₂₂ C _l2 FN ₅ O ₃ , relative molecular mass: 494.35. ZJ3757 belongs to o-formamidobenzamide insecticides. The insecticidal activity of this compound is basically the same as that of DuPont’s chlorantraniliprole. It belongs to the insecticides acting on ryanodine receptors. This type of compound It can be combined with ryanodine receptors, leading to the uncontrolled and loss of Ca ²⁺ release, paralyzing the contraction function of muscle cells. It is a compound with a new mechanism of action. The pests treated with the pesticide showed rapid cessation of feeding, fatigue, nausea and muscle paralysis, until death. This type of insecticide has a wide insecticidal spectrum, a long residual effect period, low toxicity, is environmentally friendly, and has no cross-resistance with existing various insecticides. It can effectively control various Lepidoptera pests and some Coleoptera larvae and adults, and can also be used to control pests such as ants and termites.

Profenofos (profenofos) is a new variety developed by Ciba-Geigy in the late 1970s. It is a new type of propylthio-containing asymmetric phosphorothioate. It shows high activity against organophosphorus pests. Low toxicity organophosphate insecticide.

Contents of the invention

The object of the present invention is to provide an agricultural insecticide composition containing ZJ3757 and profenofos, which can make full use of the synergistic effect produced by the mixing of the two active components, improve control efficiency, reduce agricultural costs, Delays the emergence of pest resistance.

For achieving the purpose of the invention, the technical scheme adopted by the present invention is:

An agricultural insecticide composition, containing two active components, the first active component is an o-formamidobenzamide insecticide (referred to as "ZJ3757"), which has the following structural formula (I):

The second active component is profenofos, and the weight ratio of the first active component to the second active component is 1:50˜50:1.

Profenofos, English name profenofos, chemical name: O-4-bromo-2-chlorophenyl O-ethyl S-propylphosphorothioate, molecular formula: C ₁₁ H ₁₅ BrClO ₃ PS, relative molecular mass: 373.6, has the following (II) Structural formula:

The present invention provides agricultural insecticide compositions containing the active ingredient in an amount dependent on the application rate of the compound when used alone, and also on the ratio of one compound to another and the degree of synergistic effect. In the insecticide composition of the present invention, the weight ratio of ZJ3757 and profenofos is 1:50 to 6:1, preferably 1:20 to 1:1, more preferably 1:20 to 1:6 .

The agricultural insecticide composition of the present invention may further contain a carrier, which may be solid or liquid, and any carrier commonly used for preparing insecticide compositions can be used.

Suitable solid carriers include: minerals, plants, synthetic fillers and inorganic salts. The minerals include silicates, carbonates, sulfates and oxides. Silicates such as kaolin, sepiolite, nacrite, montmorillonite, mica, vermiculite, pyrophyllite, talc. Carbonates such as: calcium carbonate, dolomite. Sulfates such as ammonium sulfate, sodium sulfate, calcium sulfate. Oxides such as quicklime, magnesium lime, diatomaceous earth. Vegetables such as: citrus pomace, corn cob, chaff powder, rice husk, soybean straw powder, tobacco powder, walnut shell, sawdust. Synthetic fillers such as precipitated calcium carbonate hydrate, precipitated calcium carbonate, white carbon black. Inorganic salts such as potassium chloride, sodium chloride.

Liquid carriers include water and organic solvents. When the active ingredient is water emulsion or suspoemulsion, the organic solvent plays the role of solubilization and antifreeze. Suitable organic solvents include aromatics such as benzene, xylene, toluene, alkylbenzenes, alkylnaphthalenes, and chlorinated aromatics; chlorinated aliphatics such as vinyl chloride, chloroform, methylene chloride, chloroform, carbon tetrachloride and polychloroethanes; aliphatic hydrocarbons such as petroleum distillates, cyclohexane, light mineral oils and paraffins. Alcohols such as methanol, ethanol, isopropanol, butanol, isobutanol, ethylene glycol, propylene glycol, glycerol, fatty alcohols, etc.; ethers such as methyl glycol ether, ethyl glycol ether, petroleum ether. Ketones such as acetone, methyl ethyl ketone, methyl isobutyl ketone, cyclohexanone and isophorone, N-methyl-pyrrolidone; special solvents also include dimethylformamide, dimethyl sulfoxide, polyethylene glycol , Capronitrile; vegetable oil and methylated vegetable oil. The above-mentioned organic solvents may be used alone, or in combination, or in combination with water.

The auxiliary agent of the present invention may include one or more of surfactants, defoamers, thickeners, suspending agents and antifreezing agents as required, and may also include other auxiliary agents commonly used in this industry as required.

Surfactants can be emulsifiers, dispersants, stabilizers or wetting agents; can be ionic or nonionic. Suitable surfactants include: sodium and calcium salts of polyacrylic acid and lignosulfonic acid; polycondensation products of fatty acids or fatty amines having at least 12 carbon atoms in the molecule with ethylene oxide and/or propylene oxide; glycerol, Fatty acid esters of 1-lauryl alcohol, 1-myristyl alcohol, sorbitol, sucrose or pentaerythritol; and their polycondensation products with ethylene oxide and/or propylene oxide; sulfate salts or Sulfonates; alkali or alkaline earth metal salts, preferably sodium, of sulfuric or sulfonic acids containing at least 10 carbon atoms in the molecule, such as sodium lauryl sulfate, sodium secondary alkyl sulfate, ricinium sulfonate Sodium salt of sesame oil, sodium alkylarylsulfonate and sodium dodecylbenzenesulfonate; polymer of ethylene oxide, copolymer of ethylene oxide and propylene oxide.

Emulsifiers include nonionic emulsifiers and commercially available emulsifiers. Non-ionic emulsifiers are preferably polyoxyethylene fatty acid esters, polyoxyethylene fatty alcohol ethers and polyoxyethylene fatty ammonia, such as ethoxylated castor oil, polyoxyethylene (n ₂₀ ) phenylethylphenol ether oleate, Alkylaryl polyoxyethylene polyoxypropylene ether, alkylaryl formaldehyde resin polyoxyethylene ether, tristyrylphenol polyoxyethylene (n ₂₀ ), ether phosphorylated triethanolamine salt, diphenylethylphenol polyoxyethylene Oxyethylene ether (n ₁₈ ) formaldehyde condensate, diphenylphenol polyoxyethylene (n ₁₈ ) polyoxypropylene ether (n ₂₀ ), etc. Commercially available emulsifiers include: Agricultural Milk 0201B, Agricultural Milk 0203B, Agricultural Milk 100 ^# , Agricultural Milk 500 ^# , Agricultural Milk 600 ^# , Agricultural Milk 600-2 ^# , Agricultural Milk 1601, Agricultural Milk 2201, Agricultural Milk NP-10 , Nongru NP-15, Nongru 507 ^# , Nongru OX-635, Nongru OX-622, Nongru OX-653, Nongru OX-667, Nongru CS-7, Ningru 36 ^# .

The dispersant of the present invention includes: sodium lignosulfonate, pull-open powder, calcium lignosulfonate, methylnaphthalenesulfonic acid formaldehyde condensate, naphthalenesulfonic acid formaldehyde condensate, sodium methylenenaphthalenesulfonate, oil Sodium acid methyl amino ethyl sulfonate, epoxy polyether, p-tert-butyl ether, dibutyl naphthalene sulfonic acid formaldehyde condensate, phosphates such as sodium hexametaphosphate, alkylphenol polyoxyethylene phosphate, alkanes Alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, N-methyl-fatty acyl-taurine sodium alkylphenol polyoxyethylene ether formaldehyde condensate, aralkylphenol polyoxyethylene ether phosphate ester alkylphenol poly Oxyethylene ether, castor oil ethylene oxide adduct, ethylene oxide propylene oxide block copolymer alkylphenol polyoxyethylene ether formaldehyde condensate, alkylphenol polyoxyethylene polyoxypropylene ether and methyl fiber white.

The wetting agent of the present invention includes: sodium lauryl sulfate, sodium alkyl alcohol polyoxyethylene ether sulfate, octylphenol polyoxyethylene ether sulfate, alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, Sodium Alkyl Sulfonate, Sodium Dodecyl Benzene Sulfonate, Sodium Alkyl Naphthalene Sulfonate, Alkyl Succinate Sulfonate, Sodium Lauryl Polyoxyethylene Ether Sulfonate, Sodium Alkylamide Taurate, Fatty alcohol polyoxyethylene ether, alkylphenol polyoxyethylene ether, polyoxyethylene polyoxypropylene block polymer, sorbitan fatty acid ester polyoxyethylene ether, etc.

The thickener of the present invention can be artificially synthesized, such as carboxymethyl alcohol, polyvinyl alcohol or polyvinyl acetate; it can also be a natural water-soluble polymer, such as xanthan gum, gelatin, gum arabic , polyvinylpyrrolidone, aluminum magnesium silicate, polyvinyl alcohol, polyethylene glycol, phenolic resin, shellac, carboxymethyl cellulose and sodium alginate, etc.

The defoaming agent of the present invention is preferably: foam enemy, silicones, C _{8 ~ 10} fatty alcohols, C _{10 ~ 20} saturated fatty acids and amides.

The insecticide composition provided by the invention can be configured into emulsifiable oil, suspoemulsion, powder, granule; The percentage content is 0.5-95%.

When formulated as an emulsifiable concentrate, preferably the emulsifiable concentrate contains 39% to 42% by weight of the insecticide composition. The above-mentioned powder is preferably a wettable powder, and when configured as a wettable powder, it is preferable that the wettable powder contains 39% to 42% by weight of the insecticide composition. The above-mentioned granules are preferably water-dispersible granules. When configured as water-dispersible granules, the water-dispersible granules preferably contain 40% to 42% by weight of the insecticide composition. When formulated as a suspoemulsion, preferably the suspoemulsion contains 39% to 50% by weight of the insecticide composition.

When the agricultural insecticide composition of the present invention is applied in the field, the application dose is preferably 250g ai//hm ² -300ga.i.//hm ² .

The agricultural insecticide composition of the present invention can be directly made into a finished preparation form, that is, each material in the composition has been mixed and used directly for insecticide; (tank) for direct mixing. The concentrates of the present invention are generally mixed with water to obtain the desired concentration of active substance.

The agricultural insecticide composition of the present invention is particularly suitable for controlling Lepidoptera pests, and is suitable for various plants, such as rice, wheat, cotton, pepper, sweet pepper, eggplant, tomato, kidney bean, cowpea, leek, lettuce , Chinese cabbage, sunflower, lychee, tobacco, rubber, flowers, Chinese medicinal materials and lawn, etc.

The agricultural insecticide composition of the present invention can be applied by common methods, such as pouring, spraying and spraying. The amount of application varies with climatic conditions or crop status, and the application time can be before or after pest damage. The duration of the protective effect is usually related to the content of the individual compounds in the composition, but also to external factors, such as climate, which can be mitigated by using appropriate formulations.

The agricultural insecticide composition of the present invention can also be used in combination with other compounds with herbicidal and bactericidal properties, and can also be used in combination with nematicides, protective agents, growth regulators, plant nutrients or soil regulators.

The agricultural insecticide composition of the present invention has the following advantages:

(1) The combination of the two insecticides in the composition exhibits a strong synergistic effect within a certain ratio range, and the insecticidal effect of the mixed composition is significantly improved compared with its single agent, and has quick-acting properties Good and long-lasting characteristics;

(2) Reduce the dosage and reduce the cost of medication for farmers;

(3) The compound product is highly effective against rice leaf roller and cotton bollworm which are resistant to most pesticides;

(4) Use two kinds of pesticides to rationally mix different modes of action and different mechanisms of action on pests, which not only prolongs the service life of pesticides, but also delays the generation of pest resistance.

Detailed ways

The following examples are used to illustrate specific embodiments of the present invention, but do not limit the present invention to these specific embodiments. Those skilled in the art will realize that the present invention covers all alternatives, modifications and equivalents as may be included within the scope of the claims.

The proportioning percentages of all solid preparations in the present invention are weight percentages, and the proportioning percentages of liquid preparations are volume percentages; the treatment doses of biologically active parts are all effective contents.

1. Preparation

1. Preparation of EC

According to the formula requirements, add the solvent, the original drug and the emulsifier respectively, mix evenly, and if necessary, heat and dissolve in a water bath to obtain a transparent emulsifiable oil.

Embodiment 1 (42% emulsifiable concentrate)

ZJ37576%, profenofos 36%, Nongru 2201 ^# 7.5%, Nongru 600 ^# 4.5%, dimethylformamide 8%, S-200 (the main components are octane and heptane, Jiangsu Yangzhou Hualun Chemical Co., Ltd. Company) make up to 100%.

Embodiment 2 (40% emulsifiable concentrate)

ZJ3757 4%, profenofos 36%, Nongru 500 ^# 5%, Nongru 0201B 10%, dimethylformamide 12%, S-200 (the main components are octane and heptane, Jiangsu Yangzhou Hualun Chemical Co., Ltd. Company) make up to 100%.

Embodiment 3 (39% emulsifiable concentrate)

ZJ37573%, profenofos 36%, Nongru 0203B 6%, Nongru 0201B 9%, cyclohexanone 8%, S-200 (mainly octane and heptane, Jiangsu Yangzhou Hualun Chemical Co., Ltd.) 100%.

2. Preparation of wettable powder

According to the requirements of the formula, the original drug, various additives and fillers are fully mixed, and the processed product is obtained after being pulverized by an ultra-fine pulverizer.

Embodiment 4 (40% wettable powder)

ZJ37574%, profenofos 36%, sodium dodecylbenzene sulfonate 2.0%, white carbon black 10%, sodium lignosulfonate 10%, light calcium carbonate make up to 100%.

Embodiment 5 (42% wettable powder)

ZJ37577%, profenofos 35%, sodium lauryl sulfate 1.5%, naphthalene sulfonate formaldehyde condensate 5%, sodium lignosulfonate 3%, white carbon black 12%, light calcium carbonate to 100%.

Embodiment 6 (42% wettable powder)

ZJ3757 6%, profenofos 36%, sodium dodecylbenzene sulfonate 1.8%, p-tert-butyl ether 2%, white carbon black 12%, sodium lignosulfonate 10%, light calcium carbonate to 100% %.

Embodiment 7 (39% wettable powder)

ZJ37573%, profenofos 36%, sodium dodecylbenzenesulfonate 2%, sodium naphthalenesulfonate formaldehyde condensate 9%, sodium lignosulfonate 3%, white carbon black 10%, light calcium carbonate supplemented to 100%.

3. Preparation of water dispersible granules

Mix and pulverize the original drug, powdery carrier, dispersant, wetting agent and binder, add water and knead, then add to a granulator equipped with a certain size screen for granulation. Then dry and sieve (according to the range of the sieve) to obtain granular products.

Embodiment 8 (42% water dispersible granules)

ZJ37576%, profenofos 36%, sodium lignosulfonate 15%, sodium methylnaphthalene sulfonate formaldehyde condensate 5%, epoxy polyether 5%, white carbon black 20%, kaolin to make up to 100%.

Embodiment 9 (40% water dispersible granules)

ZJ37574%, profenofos 36%, N-methyl-oleoyl-sodium taurate 8%, naphtholsulfonic acid formaldehyde condensate 10%, white carbon black 20%, kaolin supplemented to 100%.

4. Preparation of suspoemulsion

According to the requirements of the formula, the solid original drug is made into a suspension, the liquid original drug is added with an emulsifier to make an oil phase, and the two are mixed in proportion, sheared and stirred evenly to make a suspoemulsion.

Embodiment 10 (42% suspoemulsion)

ZJ37576%, profenofos 36%, sodium methylene naphthalene sulfonate 3.5%, Nongru 0201B 2.0%, white carbon black 0.2%, xanthan gum 0.1%, ethylene glycol 4%, tributyl phosphate 0.2% , make up the water to 100%.

Embodiment 11 (40% suspoemulsion)

ZJ37574%, profenofos 36%, sodium methylene naphthalene sulfonate 3.5%, Nongru 0201B 2.0%, white carbon black 0.2%, xanthan gum 0.1%, ethylene glycol 4%, tributyl phosphate 0.2% , make up the water to 100%.

Embodiment 12 (39% suspoemulsion)

ZJ37573%, profenofos 36%, sodium methylene naphthalene sulfonate 3.5%, Nongru 0201B 2.0%, white carbon black 0.2%, xanthan gum 0.1%, ethylene glycol 4%, tributyl phosphate 0.2% , make up the water to 100%.

Embodiment 13 (50% suspoemulsion)

ZJ37575%, Profenofos 45%, Sodium Methylene Naphthalene Sulfonate 3.5%, Nongru 0201B 2.0%, White Carbon Black 0.2%, Xanthan Gum 0.1%, Ethylene Glycol 4%, Tributyl Phosphate 0.2% , make up the water to 100%.

2. Determination of biological activity

In order to further understand the toxicity of the combination of ZJ3757 and profenofos to pests, a large number of formula screening tests were carried out. The test refers to the Indoor Bioassay Test Guidelines for Insecticides and Pesticides (Agricultural Industry Standard NY/T1154.7-2006) and the creation of Pesticide Biological Activity Evaluation SOP (Insecticide Volume), using the dipping method.

The combined effect is calculated using the following method:

Theoretical mixture toxicity index (TTI) = toxicity index of A × content of A in the mixture (%)

Toxicity index of +B × B content in the mixture (%)

If the co-toxicity coefficient is greater than 120, it indicates a synergistic effect; if it is less than 80, it indicates an antagonistic effect; if it is greater than 80 but less than 120, it indicates an additive effect.

The results showed that the mixture of ZJ3757·profenofos had high insecticidal activity on the tested targets, and the mixture of ZJ3757 and profenofos showed a significant synergistic effect, and the activity of the mixture was much higher than that of the control single agent. The results are shown in examples 14-15.

Example 14

The combined synergistic effect of ZJ3757 and profenofos is shown in Table 1 below, and the test object is Helicoverpa armigera.

Table 1

deal with Proportion _LC50 (mg/L) measured toxicity index theoretical virulence index co-toxicity coefficient ZJ3757: Profenofos 1:1 0.865 64.39 50.32 127.97 ZJ3757: Profenofos 1:6 2.774 20.08 14.83 135.39 ZJ3757: Profenofos 1:9 3.683 15.12 10.57 143.05 ZJ3757: Profenofos 1:20 7.381 7.55 5.37 140.59 ZJ3757: Profenofos 1:50 16.209 3.44 2.58 132.96 ZJ3757: Profenofos 6:1 0.503 110.74 85.81 129.05 Profenofos- - 87.564 0.64 - - ZJ3757 - 0.557 100.0 - -

Example 15

The combined synergistic effect of ZJ3757 and profenofos is shown in Table 2 below, and the test object is Cnaphalocrocis medinalis.

Table 2

deal with Proportion _LC50 (mg/L) measured toxicity index theoretical virulence index co-toxicity coefficient ZJ3757: Profenofos 1:1 3.018 71.17 51.84 137.29 ZJ3757: Profenofos 1:6 8.801 24.41 17.44 139.94 ZJ3757: Profenofos 1:9 11.063 19.42 13.31 145.85 ZJ3757: Profenofos 1:20 18.873 11.38 8.27 137.67 ZJ3757: Profenofos 1:50 28.873 7.44 5.57 133.59 ZJ3757: Profenofos 6:1 1.974 108.81 86.24 126.18 Profenofos - 58.363 3.68 - - ZJ3757 - 2.148 100.0 - -

3. The effect of field plot control

Example 16 Field efficacy test of ZJ3757·profenofos mixed against rice leaf roller

The control effect of each formulation on rice leaf roller was determined under field conditions. The test sites are located in Kaihua City, Zhejiang Province, and are single-season hybrid rice. The pesticide was applied once during the test, and it was the rice tillering stage when the pesticide was applied, and the rice leaf roller mainly had young larvae. The application rate is 750kg/hm ² . 20% ZJ3757 suspending agent: 35g ai//hm ² , 40% profenofos emulsifiable concentrate: 600g ai//hm ² , the dosage of each compound preparation is 300g ai//hm ² , use "Hemei" HM-16A type back Type electric sprayer, spray evenly on the leaves of the plants. Plot area: 25m ² , repeated 4 times, arranged in random blocks. According to the provisions of "GB-T 17980.1-2000 Pesticide Field Efficacy Test Guidelines (1) - Insecticides Control Lepidoptera Boring Pests of Rice", each plot is sampled at 5 points with interlaced jumps, and 5 clusters are investigated in each row , investigated 25 clumps of rice in total, and investigated the number of curled leaves and the total number of leaves in each clump.

Test result: use preparation embodiment 1 (42% emulsifiable concentrate), embodiment 2 (40% emulsifiable concentrate), embodiment 3 (39% emulsifiable concentrate), embodiment 10 (42% suspoemulsion), embodiment 11 (40% suspoemulsion ) and Example 12 (39% suspoemulsion) 300g ai/ ^hm The 3d control effect after the drug is 84.9%-87.8%, the 10d control effect after the drug is 86.4%-96.3%, and the 15d control effect after the drug still reaches 80.4% -86.8%, the control effect is better than 40% profenofos emulsifiable concentrate 600g ai/hm ² and 20% ZJ3757 suspension concentrate 35g ai/hm ² , with good quick effect and long lasting effect.

Table 3 The result of the compound preparation of the present invention on the field plot control of rice leaf roller

Example 17 Field efficacy test of ZJ3757-profenofos mixture on cotton bollworm

The control effect of the formulation on cotton bollworm was determined under field conditions. The test site is located in Huaining County, Anhui Province. The pesticide was applied once during the test, and it was the peak period of egg hatching when the pesticide was applied, and the worm state was mainly young larvae. 20% ZJ3757 suspending agent: 25g ai//hm ² , 40% profenofos emulsifiable concentrate: 600g ai//hm ² , the dosage of each compound preparation is 250g ai//hm ² . Use the "Hemei" HM-16A knapsack electric sprayer to spray evenly on the leaves of the plants. Plot area: 25m ² , repeated 4 times, arranged in random blocks. The application rate is 450kg/hm ² . Use the "Hemei" HM-16A knapsack electric sprayer to spray evenly on the leaves of the plants. The test investigation was carried out according to the regulations of pesticide field efficacy test guidelines (1)——Insecticide control of cotton bollworm, 5 points were randomly selected in the middle row of each plot, 5 plants were investigated at each point, and a total of 25 plants were investigated. base.

Test result: use preparation embodiment 1 (42% emulsifiable concentrate), embodiment 2 (40% emulsifiable concentrate), embodiment 3 (39% emulsifiable concentrate), embodiment 10 (42% suspoemulsion), embodiment 11 (40% suspoemulsion ) and Example 12 (39% suspoemulsion) 250g ai/ ^hm The 3d control effect after the drug is 83.4%-87.4%, the 7d control effect after the drug is 93.5%-96.8%, and the 14d control effect after the drug still reaches 81.5% -85.9%, the control effect is better than 40% profenofos emulsifiable concentrate 60g ai/hm ² and 20% ZJ3757 suspension concentrate 25g ai/hm ² , with good quick effect and long lasting effect.

Table 4 compound preparation of the present invention is to control test result of field plot of cotton bollworm

Claims (10)

1. An agricultural insecticide composition is characterized in that it contains two kinds of active components, the first active component is o-formamidobenzamide insecticide ZJ3757, which has the structural formula shown in (I):

The second active component is profenofos, and the weight ratio of the first active component to the second active component is 1:50˜6:1. 2. The agricultural insecticide composition according to claim 1, characterized in that the weight ratio of the first active component to the second active component is 1:20˜1:1. 3. The agricultural insecticide composition according to claim 2, characterized in that the weight ratio of the first active component to the second active component is 1:20˜1:6. 4. According to the agricultural insecticide composition described in one of claims 1 to 3, it is characterized in that said insecticide composition is formulated into emulsifiable concentrate, suspension concentrate, suspoemulsion, microemulsion, water emulsion, powder, granule formulation or capsule, the weight percentage of the insecticide composition contained in the emulsifiable concentrate, suspension concentrate, suspoemulsion, microemulsion, water emulsion, powder, granule or capsule is 0.5-95%. 5. According to the agricultural pesticide composition described in claim 4, it is characterized in that said powder is wettable powder or soluble powder, and said granule is water-dispersible granule. 6. according to the described agricultural insecticide composition of claim 4, it is characterized in that containing the insecticide composition of 39%～42% weight in the described emulsifiable concentrate, containing 39%～50% weight of the insecticide composition in the described suspoemulsion Insecticide composition. 7. According to the agricultural insecticide composition described in claim 5, it is characterized in that the insecticide composition contains 39%～42% weight in the described soluble powder, contains 40%～40%～ 42% by weight of the insecticide composition. 8. According to the application of the agricultural insecticide composition described in claim 1, it is characterized in that it is used for controlling Lepidoptera pests. 9. According to the application of the agricultural insecticide composition described in claim 8, it is characterized in that it is used for controlling rice leaf roller and cotton bollworm. 10. The application of the agricultural insecticide composition according to claim 8, characterized in that the application dose of the insecticide composition in the field is 250g ai//hm ² to 300g ai//hm ² .