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BR0213207A - remodelagem e glicoconjugação de peptìdeos - Google Patents

remodelagem e glicoconjugação de peptìdeos

Info

Publication number
BR0213207A
BR0213207A BRPI0213207-9A BR0213207A BR0213207A BR 0213207 A BR0213207 A BR 0213207A BR 0213207 A BR0213207 A BR 0213207A BR 0213207 A BR0213207 A BR 0213207A
Authority
BR
Brazil
Prior art keywords
peptide
remodeling
glycoconjugation
addition
glycojugation
Prior art date
Application number
BRPI0213207-9A
Other languages
English (en)
Other versions
BRPI0213207B1 (pt
Inventor
Shawn De Frees
David Zopf
Robert Bayer
Caryn Bowe
David Hakes
Xi Chen
Original Assignee
Neose Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neose Technologies Inc filed Critical Neose Technologies Inc
Publication of BR0213207A publication Critical patent/BR0213207A/pt
Publication of BRPI0213207B1 publication Critical patent/BRPI0213207B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6437—Coagulation factor VIIa (3.4.21.21)
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    • A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids
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Abstract

"REMODELAGEM E GLICOCONJUGAçãO DE PEPTìDEOS". A invenção inclui processos e composições para remodelação de uma molécula de peptídeo, incluindo a adição ou apagamento de um ou mais grupos glicosila em relação a um peptídeo e/ou a adição de um grupo de modificação do peptídeo.
BRPI0213207-9A 2001-10-10 2002-10-09 Processo in vitro, isento de células, para a remodelagem de um peptídeo e processos para formar um conjugado entre peptídeos e um grupo de modificação BRPI0213207B1 (pt)

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US32852301P 2001-10-10 2001-10-10
US60/328,523 2001-10-10
US34469201P 2001-10-19 2001-10-19
US60/344,692 2001-10-19
US33423301P 2001-11-28 2001-11-28
US33430101P 2001-11-28 2001-11-28
US38729202P 2002-06-07 2002-06-07
US60/387,292 2002-06-07
US39177702P 2002-06-25 2002-06-25
US39659402P 2002-07-17 2002-07-17
US60/396,594 2002-07-17
US40424902P 2002-08-16 2002-08-16
US60/404,249 2002-08-16
US40752702P 2002-08-28 2002-08-28
PCT/US2002/032263 WO2003031464A2 (en) 2001-10-10 2002-10-09 Remodeling and glycoconjugation of peptides

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PT2279755E (pt) 2014-06-04
JP2010120954A (ja) 2010-06-03
LU92359I2 (fr) 2014-03-24
BRPI0213207B1 (pt) 2021-06-15
AU2009202405B2 (en) 2011-09-22
CN1635901A (zh) 2005-07-06
HK1080090A1 (en) 2006-04-21
FR14C0007I2 (fr) 2015-01-02
ES2556338T3 (es) 2016-01-15
EP2042196B1 (en) 2016-07-13
CN1635901B (zh) 2012-03-28
EP2279754A2 (en) 2011-02-02
EP2279754A3 (en) 2011-06-22
ES2561985T3 (es) 2016-03-01
EP2292271A3 (en) 2011-09-14
EP1578771A4 (en) 2007-02-21
MXPA04003333A (es) 2006-02-22
HK1080090B (zh) 2012-12-14
US7276475B2 (en) 2007-10-02
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AU2009202405A1 (en) 2009-07-16
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DK1578771T3 (da) 2013-06-10
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JP5739632B2 (ja) 2015-06-24
JP5258809B2 (ja) 2013-08-07
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SG159381A1 (en) 2010-03-30
NL300912I2 (nl) 2018-09-27
BE2014C004I2 (pt) 2021-11-22
EP2042196A3 (en) 2009-07-22
JP2011006479A (ja) 2011-01-13
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WO2003031464A2 (en) 2003-04-17
JP5376912B2 (ja) 2013-12-25
HK1154498A1 (en) 2012-04-27
IL161251A0 (en) 2004-09-27
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US20050106658A1 (en) 2005-05-19
JP2014087370A (ja) 2014-05-15
EP2292271A2 (en) 2011-03-09
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WO2003031464A3 (en) 2006-03-02

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