YU19399A - Lokalni anestetik za spoljnu upotrebu - Google Patents
Lokalni anestetik za spoljnu upotrebuInfo
- Publication number
- YU19399A YU19399A YU19399A YU19399A YU19399A YU 19399 A YU19399 A YU 19399A YU 19399 A YU19399 A YU 19399A YU 19399 A YU19399 A YU 19399A YU 19399 A YU19399 A YU 19399A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- local anesthetic
- external use
- mesna
- pharmaceutical formulations
- surgical procedures
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cyclones (AREA)
- External Artificial Organs (AREA)
Abstract
Lokalni anestetik za spoljnu upotrebu dobijen mešanjem a) aktivnog sastojka izabranog izmedju lidokaina, pirokaina, i njihovih farmaceutski prihvatljivih soli, b) akceleratora perkutane apsorpcije, c) etanola i/ili izopropil alkohola, i d) vode, pri čemu je poželjno da odnos mešanja etanola i/ili izopropril alkohola i vode bude 0.5 do 1.2 izraženo težinski, a poželjno je da pH bude od 6.0 do 8.5. Tako je obezbedjen tip lokalnog anestetika za spoljnu upotrebu sa perkutanom apsorpcijom, koji se komforno upotrebljava kada se primenjuje i uklanja, koji je primenljiv na široku površinu kože, i koji je odličan u pogledu perkutane apsorpcije i brzog dejstva, kao što je odličan i u pogledu stabilnosti.[Topical pharmaceutical formulations containing sodium 2-mercaptoethanesulfonate (MESNA), the use of MESNA for the preparation of pharmaceutical formulations intended to be used in surgical procedures that involve the dissection of tissues of the use of MESNA in said surgical procedures.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP27081396 | 1996-10-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| YU19399A true YU19399A (sh) | 2001-09-28 |
Family
ID=17491384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU19399A YU19399A (sh) | 1996-10-14 | 1997-10-06 | Lokalni anestetik za spoljnu upotrebu |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US6429228B1 (sh) |
| EP (1) | EP0957906B1 (sh) |
| JP (1) | JP2001503035A (sh) |
| KR (1) | KR20000049125A (sh) |
| CN (1) | CN1135104C (sh) |
| AT (1) | ATE214599T1 (sh) |
| AU (1) | AU731946B2 (sh) |
| BG (1) | BG103325A (sh) |
| BR (1) | BR9711911A (sh) |
| CA (1) | CA2268535A1 (sh) |
| CZ (1) | CZ129899A3 (sh) |
| DE (1) | DE69711237T2 (sh) |
| DK (1) | DK0957906T3 (sh) |
| EA (1) | EA001611B1 (sh) |
| EE (1) | EE03743B1 (sh) |
| ES (1) | ES2173485T3 (sh) |
| HU (1) | HUP9904109A3 (sh) |
| ID (1) | ID21773A (sh) |
| IL (1) | IL129335A (sh) |
| LT (1) | LT4585B (sh) |
| MY (1) | MY118301A (sh) |
| NO (1) | NO991731L (sh) |
| NZ (1) | NZ335056A (sh) |
| PL (1) | PL332724A1 (sh) |
| PT (1) | PT957906E (sh) |
| RO (1) | RO120604B1 (sh) |
| SK (1) | SK284332B6 (sh) |
| TR (1) | TR199900814T2 (sh) |
| TW (1) | TW450815B (sh) |
| WO (1) | WO1998016212A1 (sh) |
| YU (1) | YU19399A (sh) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6528086B2 (en) * | 1999-09-28 | 2003-03-04 | Zars, Inc. | Methods and apparatus for drug delivery involving phase changing formulations |
| WO2001054679A2 (en) * | 2000-01-27 | 2001-08-02 | Children's Hospital Research Foundation | Transdermal composition containing an anesthetic and a vasodilator agent |
| US6894078B2 (en) * | 2001-09-17 | 2005-05-17 | James G. Castillo | Alcohol based topical anesthetic formulation and method |
| US20040076671A1 (en) * | 2002-10-21 | 2004-04-22 | Aletha Tippett | Methods and compositions for topical wound treatment |
| US20040077593A1 (en) * | 2002-10-21 | 2004-04-22 | Marron Susan M. | Numbing gel for hair removal |
| AU2004224329B2 (en) * | 2003-03-21 | 2009-07-09 | Nexmed (Holdings), Inc. | Compositions and methods for treatment of premature ejaculation |
| US20050014823A1 (en) * | 2003-07-17 | 2005-01-20 | Soderlund Patrick L. | Topical anesthetic composition and method of administration |
| EP1782831B1 (en) * | 2004-08-18 | 2011-10-19 | Medrx Co., Ltd. | External preparation |
| WO2007002304A2 (en) | 2005-06-22 | 2007-01-04 | Vnus Medical Technologies, Inc. | Methods and apparatus for introducing tumescent fluid to body tissue |
| EP2209450A4 (en) * | 2007-11-07 | 2013-09-25 | Svip5 Llc | SLOW RELEASE OF LOCAL ANESTHESIC ORGANIC SALTS FOR PAIN RELIEF |
| NZ591834A (en) | 2008-10-02 | 2011-12-22 | Mylan Inc | Method of making a multilayer adhesive laminate |
| DE102009007152A1 (de) * | 2009-02-02 | 2010-08-05 | Müller-Glewe, Gunter | Ultraschall-Gel |
| NZ602540A (en) * | 2010-04-01 | 2014-05-30 | Pharmanest Ab | Bioadhesive compositions of local anaesthetics |
| CN102018696B (zh) * | 2010-11-22 | 2013-07-03 | 北京泰德制药股份有限公司 | 一种含有利多卡因或其药用盐的皮肤外用制剂 |
| JP5512891B2 (ja) * | 2011-06-20 | 2014-06-04 | 久光製薬株式会社 | リドカイン含有パップ剤 |
| FR2983731B1 (fr) * | 2011-12-07 | 2014-04-25 | Univ Paris Descartes | Emulsions topiques a base de melanges eutectiques d'anesthesiques locaux et d'acide gras |
| CN103505791A (zh) * | 2012-06-28 | 2014-01-15 | 杨德普 | 透皮吸收局麻无痛注射穿刺酒精棉片 |
| CN103550675A (zh) * | 2013-09-04 | 2014-02-05 | 赵会霞 | 一种止痛贴 |
| KR102080860B1 (ko) * | 2018-04-11 | 2020-02-24 | 숭실대학교산학협력단 | 미세구조의 피부 흡수 증강제, 미세구조의 피부 흡수 증강제를 포함하는 국소 마취제, 및 미세구조의 피부 흡수 증강제를 포함하는 국소 마취제를 이용한 마취 방법 |
| CN110090197A (zh) * | 2019-04-19 | 2019-08-06 | 广州芮一生物科技有限公司 | 一种可成膜的麻醉面膜膏 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4954487A (en) * | 1979-01-08 | 1990-09-04 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions |
| CA1165240A (en) | 1980-07-09 | 1984-04-10 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions |
| JPS57142913A (en) * | 1981-02-27 | 1982-09-03 | Nitto Electric Ind Co Ltd | Donor of physiologically active substance |
| US4748022A (en) | 1985-03-25 | 1988-05-31 | Busciglio John A | Topical composition |
| US4764381A (en) * | 1985-12-06 | 1988-08-16 | Key Pharmaceuticals, Inc. | Percutaneous penetration enhancer of oleic acid and 2-ethyl-1, 3-hexanediol |
| US5209724A (en) | 1988-04-11 | 1993-05-11 | Dhaliwal Avtar S | Composite anesthetic article and method of use |
| US5378730A (en) * | 1988-06-09 | 1995-01-03 | Alza Corporation | Permeation enhancer comprising ethanol and monoglycerides |
| EP0378644A1 (en) * | 1988-06-09 | 1990-07-25 | Alza Corporation | Permeation enhancer comprising ethanol and glycerol monooleate |
| JPH0755167B2 (ja) * | 1988-09-21 | 1995-06-14 | 松下電器産業株式会社 | 移動体 |
| US4892737A (en) * | 1988-09-22 | 1990-01-09 | University Of Florida | Composition and method for enhancing permeability of topical drugs |
| GB9101986D0 (en) | 1991-01-30 | 1991-03-13 | Smith & Nephew | Pharmaceutical compositions |
| JPH04261119A (ja) * | 1991-02-13 | 1992-09-17 | Lintec Corp | 経皮吸収型貼付剤 |
| JP3115625B2 (ja) * | 1991-03-30 | 2000-12-11 | 帝國製薬株式会社 | リドカイン含有外用貼付剤 |
| JP2775203B2 (ja) | 1991-05-11 | 1998-07-16 | 久光製薬株式会社 | 吸収促進組成物 |
| JPH0640947A (ja) * | 1992-07-28 | 1994-02-15 | T T S Gijutsu Kenkyusho:Kk | 経皮吸収製剤用組成物および経皮吸収製剤 |
| JPH0694891A (ja) | 1992-09-10 | 1994-04-08 | Kawasaki Heavy Ind Ltd | 使用済燃料貯蔵・輸送容器 |
| JPH08286701A (ja) | 1995-04-11 | 1996-11-01 | Nissan Motor Co Ltd | 複数ロボット制御方法およびシステム |
-
1997
- 1997-10-06 AU AU43996/97A patent/AU731946B2/en not_active Ceased
- 1997-10-06 PL PL97332724A patent/PL332724A1/xx unknown
- 1997-10-06 JP JP10518171A patent/JP2001503035A/ja not_active Ceased
- 1997-10-06 TR TR1999/00814T patent/TR199900814T2/xx unknown
- 1997-10-06 CZ CZ991298A patent/CZ129899A3/cs unknown
- 1997-10-06 YU YU19399A patent/YU19399A/sh unknown
- 1997-10-06 WO PCT/JP1997/003567 patent/WO1998016212A1/en not_active Application Discontinuation
- 1997-10-06 US US09/284,124 patent/US6429228B1/en not_active Expired - Fee Related
- 1997-10-06 HU HU9904109A patent/HUP9904109A3/hu unknown
- 1997-10-06 SK SK482-99A patent/SK284332B6/sk unknown
- 1997-10-06 AT AT97942259T patent/ATE214599T1/de not_active IP Right Cessation
- 1997-10-06 ID IDW990176A patent/ID21773A/id unknown
- 1997-10-06 EA EA199900376A patent/EA001611B1/ru not_active IP Right Cessation
- 1997-10-06 PT PT97942259T patent/PT957906E/pt unknown
- 1997-10-06 DE DE69711237T patent/DE69711237T2/de not_active Expired - Lifetime
- 1997-10-06 BR BR9711911-3A patent/BR9711911A/pt not_active IP Right Cessation
- 1997-10-06 CN CNB97180639XA patent/CN1135104C/zh not_active Expired - Fee Related
- 1997-10-06 EE EEP199900144A patent/EE03743B1/xx not_active IP Right Cessation
- 1997-10-06 EP EP97942259A patent/EP0957906B1/en not_active Expired - Lifetime
- 1997-10-06 IL IL12933597A patent/IL129335A/en not_active IP Right Cessation
- 1997-10-06 ES ES97942259T patent/ES2173485T3/es not_active Expired - Lifetime
- 1997-10-06 RO RO99-00416A patent/RO120604B1/ro unknown
- 1997-10-06 CA CA002268535A patent/CA2268535A1/en not_active Abandoned
- 1997-10-06 KR KR1019990703209A patent/KR20000049125A/ko not_active Application Discontinuation
- 1997-10-06 DK DK97942259T patent/DK0957906T3/da active
- 1997-10-06 NZ NZ335056A patent/NZ335056A/xx unknown
- 1997-10-10 MY MYPI97004764A patent/MY118301A/en unknown
- 1997-10-13 TW TW086114947A patent/TW450815B/zh not_active IP Right Cessation
-
1999
- 1999-04-13 BG BG103325A patent/BG103325A/xx unknown
- 1999-04-13 NO NO991731A patent/NO991731L/no not_active Application Discontinuation
- 1999-04-13 LT LT99-036A patent/LT4585B/lt not_active IP Right Cessation
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