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DE69916486D1 - Nicotin enthaltende pharmazeutische zusammensetzungen mit schneller transmukosaler absorption - Google Patents

Nicotin enthaltende pharmazeutische zusammensetzungen mit schneller transmukosaler absorption

Info

Publication number
DE69916486D1
DE69916486D1 DE69916486T DE69916486T DE69916486D1 DE 69916486 D1 DE69916486 D1 DE 69916486D1 DE 69916486 T DE69916486 T DE 69916486T DE 69916486 T DE69916486 T DE 69916486T DE 69916486 D1 DE69916486 D1 DE 69916486D1
Authority
DE
Germany
Prior art keywords
formulations
nicotine
pharmaceutical compositions
compositions containing
containing nicotine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69916486T
Other languages
English (en)
Other versions
DE69916486T2 (de
Inventor
Boerje Andersson
Tomas Landh
Stefan Jonn
Stefan Persson
Nils-Olof Lindberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
McNeil AB
Original Assignee
Pharmacia AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia AB filed Critical Pharmacia AB
Application granted granted Critical
Publication of DE69916486D1 publication Critical patent/DE69916486D1/de
Publication of DE69916486T2 publication Critical patent/DE69916486T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DE69916486T 1998-11-23 1999-11-04 Nicotin enthaltende pharmazeutische zusammensetzungen mit schneller transmukosaler absorption Expired - Lifetime DE69916486T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9803986A SE9803986D0 (sv) 1998-11-23 1998-11-23 New compositions
SE9803986 1998-11-23
PCT/SE1999/001983 WO2000030641A1 (en) 1998-11-23 1999-11-04 Nicotine-containing pharmaceutical compositions giving a rapid transmucosal absorption

Publications (2)

Publication Number Publication Date
DE69916486D1 true DE69916486D1 (de) 2004-05-19
DE69916486T2 DE69916486T2 (de) 2004-08-26

Family

ID=20413363

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69916486T Expired - Lifetime DE69916486T2 (de) 1998-11-23 1999-11-04 Nicotin enthaltende pharmazeutische zusammensetzungen mit schneller transmukosaler absorption

Country Status (12)

Country Link
US (1) US6676959B1 (de)
EP (1) EP1131071B1 (de)
JP (1) JP2002530335A (de)
AT (1) ATE264102T1 (de)
AU (1) AU1434000A (de)
DE (1) DE69916486T2 (de)
DK (1) DK1131071T3 (de)
ES (1) ES2220149T3 (de)
HK (1) HK1040614B (de)
PT (1) PT1131071E (de)
SE (1) SE9803986D0 (de)
WO (1) WO2000030641A1 (de)

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SE0103211D0 (sv) * 2001-09-27 2001-09-27 Pharmacia Ab New formulations and use thereof
SE0103210D0 (sv) * 2001-09-27 2001-09-27 Pharmacia Ab New formulations and use thereof
US20030087937A1 (en) * 2001-10-15 2003-05-08 Nils-Olof Lindberg Nicotine and cocoa powder compositions
SE0202365D0 (sv) * 2002-08-05 2002-08-05 Pharmacia Ab New formulation and use thereof
DE10251963A1 (de) * 2002-11-08 2004-05-19 Lts Lohmann Therapie-Systeme Ag Transmucosale pharmazeutische Darreichungsform
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SE0300831D0 (sv) * 2003-03-26 2003-03-26 Pharmacia Ab New formulations and use therof
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WO2008091588A1 (en) 2007-01-22 2008-07-31 Targacept, Inc. Intranasal, buccal, and sublingual administration of metanicotine analogs
WO2008099397A2 (en) * 2007-02-15 2008-08-21 Derma-Young Ltd. Compositions and methods for enhancing transmucosal delivery
US8356606B2 (en) 2007-06-01 2013-01-22 Philip Morris Usa Inc. Production of micronized encapsulated tobacco particles for tobacco flavor delivery from an oral pouch
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US9167847B2 (en) * 2009-03-16 2015-10-27 Philip Morris Usa Inc. Production of coated tobacco particles suitable for usage in a smokeless tobacoo product
CA2796346C (en) 2010-04-14 2018-10-02 Altria Client Services Inc. Preformed smokeless tobacco product
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US20110274628A1 (en) 2010-05-07 2011-11-10 Borschke August J Nicotine-containing pharmaceutical compositions
US20130078307A1 (en) 2011-09-22 2013-03-28 Niconovum Usa, Inc. Nicotine-containing pharmaceutical composition
US9474303B2 (en) 2011-09-22 2016-10-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9084439B2 (en) 2011-09-22 2015-07-21 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9629392B2 (en) 2011-09-22 2017-04-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9907748B2 (en) 2011-10-21 2018-03-06 Niconovum Usa, Inc. Excipients for nicotine-containing therapeutic compositions
US9763928B2 (en) 2012-02-10 2017-09-19 Niconovum Usa, Inc. Multi-layer nicotine-containing pharmaceutical composition
US9044035B2 (en) 2012-04-17 2015-06-02 R.J. Reynolds Tobacco Company Remelted ingestible products
US20140255452A1 (en) 2013-03-11 2014-09-11 Niconovum Usa, Inc. Method and apparatus for differentiating oral pouch products
US10799548B2 (en) * 2013-03-15 2020-10-13 Altria Client Services Llc Modifying taste and sensory irritation of smokeless tobacco and non-tobacco products
US11503853B2 (en) 2013-09-09 2022-11-22 R.J. Reynolds Tobacco Company Smokeless tobacco composition incorporating a botanical material
US10357054B2 (en) 2013-10-16 2019-07-23 R.J. Reynolds Tobacco Company Smokeless tobacco pastille
US9375033B2 (en) 2014-02-14 2016-06-28 R.J. Reynolds Tobacco Company Tobacco-containing gel composition
WO2015183801A1 (en) 2014-05-27 2015-12-03 R. J. Reynolds Tobacco Company Nicotine salts, co-crystals, and salt co-crystal complexes
US10881133B2 (en) 2015-04-16 2021-01-05 R.J. Reynolds Tobacco Company Tobacco-derived cellulosic sugar
US10869497B2 (en) 2015-09-08 2020-12-22 R.J. Reynolds Tobacco Company High-pressure cold pasteurization of tobacco material
PL3379952T3 (pl) 2015-11-25 2024-03-18 R. J. Reynolds Tobacco Company Kompleksy soli, kokryształów i kokryształów soli nikotyny
US10532046B2 (en) 2015-12-03 2020-01-14 Niconovum Usa, Inc. Multi-phase delivery compositions and products incorporating such compositions
US20170165252A1 (en) 2015-12-10 2017-06-15 Niconovum Usa Inc. Protein-enriched therapeutic composition
US10499684B2 (en) 2016-01-28 2019-12-10 R.J. Reynolds Tobacco Company Tobacco-derived flavorants
US11154087B2 (en) 2016-02-02 2021-10-26 R.J. Reynolds Tobacco Company Method for preparing flavorful compounds isolated from black liquor and products incorporating the flavorful compounds
US11091446B2 (en) 2017-03-24 2021-08-17 R.J. Reynolds Tobacco Company Methods of selectively forming substituted pyrazines
EP3681865A1 (de) 2017-09-05 2020-07-22 R. J. Reynolds Tobacco Company Nikotinsalze, co-kristalle und salz-co-kristallkomplexe
US20190307082A1 (en) 2018-04-05 2019-10-10 R.J. Reynolds Tobacco Company Oriental tobacco production methods
WO2019239356A1 (en) 2018-06-15 2019-12-19 R. J. Reynolds Tobacco Company Purification of nicotine
WO2021116855A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral compositions and methods of manufacture
WO2021116865A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Agents for oral composition
MX2023010620A (es) 2021-03-09 2023-09-19 Nicoventures Trading Ltd Productos orales y metodos de fabricacion.
US20220354785A1 (en) 2021-04-22 2022-11-10 Nicoventures Trading Limited Oral lozenge products
EP4333650A1 (de) 2021-05-06 2024-03-13 Nicoventures Trading Limited Orale zusammensetzungen und zugehörige verfahren zur verminderung von halsreizungen
WO2023053062A1 (en) 2021-09-30 2023-04-06 Nicoventures Trading Limited Oral product with a basic amine and an ion pairing agent
US20230148660A1 (en) 2021-11-15 2023-05-18 Nicoventures Trading Limited Products with enhanced sensory characteristics
WO2023248187A1 (en) 2022-06-24 2023-12-28 Nicoventures Trading Limited Oral composition comprising a receptor modulator
GB202214775D0 (en) 2022-10-07 2022-11-23 Nicoventures Trading Ltd Oral product
WO2024074839A1 (en) 2022-10-07 2024-04-11 Nicoventures Trading Limited Oral product
GB202214803D0 (en) 2022-10-07 2022-11-23 Nicoventures Trading Ltd Oral product
GB202214771D0 (en) 2022-10-07 2022-11-23 Nicoventures Trading Ltd Oral product
WO2024074843A1 (en) 2022-10-07 2024-04-11 Nicoventures Trading Limited Oral product
WO2024074842A1 (en) 2022-10-07 2024-04-11 Nicoventures Trading Limited Oral product
WO2024095163A1 (en) 2022-11-01 2024-05-10 Nicoventures Trading Limited Oral composition comprising encapsulated ph adjusting agent
GB202216465D0 (en) 2022-11-04 2022-12-21 Nicoventures Trading Ltd Oral product
TW202434271A (zh) 2022-11-04 2024-09-01 英商尼可創業貿易有限公司 口服產品
WO2024180481A1 (en) 2023-02-28 2024-09-06 Nicoventures Trading Limited Caffeine-containing oral product
GB202304445D0 (en) 2023-03-27 2023-05-10 Nicoventures Trading Ltd Oral product
GB202307279D0 (en) 2023-05-16 2023-06-28 Nicoventures Trading Ltd Oral product
GB202307278D0 (en) 2023-05-16 2023-06-28 Nicoventures Holdings Ltd Oral product
WO2025056137A1 (en) * 2023-09-12 2025-03-20 Fertin Pharma A/S Disintegrating nicotine tablet

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US5783207A (en) * 1985-05-01 1998-07-21 University Of Utah Research Foundation Selectively removable nicotine-containing dosage form for use in the transmucosal delivery of nicotine
JPS62175141A (ja) * 1986-01-29 1987-07-31 Kazuo Takatsu 複合チヨコレ−ト
US5017400A (en) * 1988-06-10 1991-05-21 Suomen Xyrofin Oy Non-cariogenic sweetener
US5004601A (en) 1988-10-14 1991-04-02 Zetachron, Inc. Low-melting moldable pharmaceutical excipient and dosage forms prepared therewith
US5098730A (en) * 1988-11-14 1992-03-24 Cultor Ltd. Dietetic sweetening composition
US5512306A (en) * 1992-06-19 1996-04-30 Pharmica Ab Smoking substitute
US5549906A (en) * 1993-07-26 1996-08-27 Pharmacia Ab Nicotine lozenge and therapeutic method for smoking cessation
US5362496A (en) * 1993-08-04 1994-11-08 Pharmetrix Corporation Method and therapeutic system for smoking cessation
JPH0940564A (ja) * 1995-07-26 1997-02-10 Taiyo Kagaku Co Ltd 悪酔予防改善用組成物
JPH0956333A (ja) * 1995-08-21 1997-03-04 Kozaburo Shiba 機能性梅チョコレート
JP2001518520A (ja) * 1997-10-03 2001-10-16 キャリー メディカル コーポレイション ニコチンレセプターアンタゴニストおよび抗抑うつ薬または抗不安薬を含有するニコチン嗜癖を治療する組成物

Also Published As

Publication number Publication date
WO2000030641A1 (en) 2000-06-02
DE69916486T2 (de) 2004-08-26
PT1131071E (pt) 2004-06-30
EP1131071A1 (de) 2001-09-12
ATE264102T1 (de) 2004-04-15
AU1434000A (en) 2000-06-13
DK1131071T3 (da) 2004-05-10
EP1131071B1 (de) 2004-04-14
ES2220149T3 (es) 2004-12-01
JP2002530335A (ja) 2002-09-17
HK1040614A1 (en) 2002-06-21
SE9803986D0 (sv) 1998-11-23
US6676959B1 (en) 2004-01-13
HK1040614B (zh) 2004-10-08

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: PFIZER HEALTH AB, STOCKHOLM, SE

8327 Change in the person/name/address of the patent owner

Owner name: MCNEIL AB, HELSINBORG, SE