TR201907599T4 - IL-17A ve IL-17F'yi bağlayan antikor molekülleri. - Google Patents
IL-17A ve IL-17F'yi bağlayan antikor molekülleri. Download PDFInfo
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- TR201907599T4 TR201907599T4 TR2019/07599T TR201907599T TR201907599T4 TR 201907599 T4 TR201907599 T4 TR 201907599T4 TR 2019/07599 T TR2019/07599 T TR 2019/07599T TR 201907599 T TR201907599 T TR 201907599T TR 201907599 T4 TR201907599 T4 TR 201907599T4
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
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- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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Abstract
Buluş hem IL-17A hem IL-17F antijenik determinantları için spesifiteye sahip antikor moleküllerine, antikor moleküllerinin terapötik kullanımlarına ve sözü edilen antikor moleküllerini üretmek için usullere ilişkindir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0620729.4A GB0620729D0 (en) | 2006-10-18 | 2006-10-18 | Biological products |
Publications (1)
Publication Number | Publication Date |
---|---|
TR201907599T4 true TR201907599T4 (tr) | 2019-06-21 |
Family
ID=37507977
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2019/07599T TR201907599T4 (tr) | 2006-10-18 | 2007-10-18 | IL-17A ve IL-17F'yi bağlayan antikor molekülleri. |
Country Status (27)
Country | Link |
---|---|
US (6) | US8303953B2 (tr) |
EP (3) | EP3524623A1 (tr) |
JP (4) | JP2010506580A (tr) |
KR (1) | KR20090078355A (tr) |
CN (1) | CN101589061B (tr) |
AU (1) | AU2007311689B2 (tr) |
BR (1) | BRPI0717768B8 (tr) |
CA (1) | CA2666458C (tr) |
CO (1) | CO6180467A2 (tr) |
CY (2) | CY1117963T1 (tr) |
DK (2) | DK2514764T3 (tr) |
EA (1) | EA029953B1 (tr) |
ES (2) | ES2588596T3 (tr) |
GB (1) | GB0620729D0 (tr) |
HR (2) | HRP20161069T1 (tr) |
HU (2) | HUE029448T2 (tr) |
IL (1) | IL198061B (tr) |
LT (1) | LT2514764T (tr) |
MX (1) | MX2009003973A (tr) |
PL (2) | PL2076539T3 (tr) |
PT (2) | PT2514764T (tr) |
RS (1) | RS55031B1 (tr) |
SG (1) | SG175652A1 (tr) |
SI (2) | SI2514764T1 (tr) |
TR (1) | TR201907599T4 (tr) |
WO (1) | WO2008047134A2 (tr) |
ZA (1) | ZA200902460B (tr) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
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JP5340537B2 (ja) | 2003-07-08 | 2013-11-13 | ジェネンテック, インコーポレイテッド | Il−17異種ポリペプチドとその治療上の用途 |
US7910703B2 (en) | 2006-03-10 | 2011-03-22 | Zymogenetics, Inc. | Antagonists to IL-17A, IL-17F, and IL-23P19 and methods of use |
US7790163B2 (en) | 2006-03-10 | 2010-09-07 | Zymogenetics, Inc. | Antibodies that bind both IL-17A and IL-17F and methods of using the same |
EP2377887A1 (en) | 2006-03-10 | 2011-10-19 | Zymogenetics Inc | Antibodies that bind both IL-17A and IL-17F and methods of using the same |
GB0612928D0 (en) | 2006-06-29 | 2006-08-09 | Ucb Sa | Biological products |
GB0620729D0 (en) | 2006-10-18 | 2006-11-29 | Ucb Sa | Biological products |
KR101197378B1 (ko) | 2007-04-30 | 2012-11-05 | 인터디지탈 테크날러지 코포레이션 | Mimo 무선 통신 시스템에서의 에러 검출 및 검사의 피드백 시그널링 |
GB0807413D0 (en) | 2008-04-23 | 2008-05-28 | Ucb Pharma Sa | Biological products |
KR20110025649A (ko) * | 2008-05-05 | 2011-03-10 | 노비뮨 에스 에이 | 항-il-17a/il-17f 교차-반응성 항체 및 그의 사용 방법 |
US8790642B2 (en) * | 2008-08-29 | 2014-07-29 | Genentech, Inc. | Cross-reactive and bispecific anti-IL-17A/F antibodies |
AU2009302113A1 (en) * | 2008-10-07 | 2010-04-15 | Novimmune Sa | IL-17-mediated transfection methods |
RU2015132478A (ru) | 2009-03-05 | 2015-12-10 | Эббви Инк. | Связывающие il-17 белки |
JP6053517B2 (ja) | 2009-05-05 | 2016-12-27 | ノヴィミュンヌ エスア | 抗il−17f抗体およびそれらの使用法 |
CN102906118B (zh) | 2010-05-20 | 2017-07-28 | 埃博灵克斯股份有限公司 | 与her3相关的生物材料 |
GB201100282D0 (en) | 2011-01-07 | 2011-02-23 | Ucb Pharma Sa | Biological methods |
US10208349B2 (en) | 2011-01-07 | 2019-02-19 | Ucb Biopharma Sprl | Lipocalin 2 as a biomarker for IL-17 inhibitor therapy efficacy |
MA34907B1 (fr) * | 2011-01-14 | 2014-02-01 | Ucb Pharma Sa | Molécules d'anticorps se liant à il-17a et il-17f |
PE20140880A1 (es) | 2011-02-08 | 2014-08-06 | Merck Patent Gmbh | Derivados de aminostatina para el tratamiento de artrosis |
WO2012125680A1 (en) * | 2011-03-16 | 2012-09-20 | Novartis Ag | Methods of treating vasculitis using an il-17 binding molecule |
WO2012138977A1 (en) * | 2011-04-06 | 2012-10-11 | Board Of Trustees Of The Leland Stanford Junior University | Structural based design of il-17 dominant negative mutants |
UA117218C2 (uk) * | 2011-05-05 | 2018-07-10 | Мерк Патент Гмбх | Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f |
CN104583239B (zh) | 2012-05-10 | 2018-09-18 | 生物蛋白有限公司 | 多特异单克隆抗体 |
JP2015521591A (ja) * | 2012-06-12 | 2015-07-30 | オレガ・バイオテック | Il−17アイソフォームのアンタゴニストおよびその使用 |
CN104231080B (zh) * | 2013-03-15 | 2019-07-02 | 中国医学科学院药物研究所 | 全人源抗人白介素17a单链抗体 |
GB201310544D0 (en) | 2013-06-13 | 2013-07-31 | Ucb Pharma Sa | Obtaining an improved therapeutic ligand |
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