[go: up one dir, main page]

RS52057B2 - Formulacija tablete sa produženim oslobađanjem koja sadrži pramipeksol ili njegovu farmaceutski prihvatljivu so - Google Patents

Formulacija tablete sa produženim oslobađanjem koja sadrži pramipeksol ili njegovu farmaceutski prihvatljivu so

Info

Publication number
RS52057B2
RS52057B2 RS20110539A RSP20110539A RS52057B2 RS 52057 B2 RS52057 B2 RS 52057B2 RS 20110539 A RS20110539 A RS 20110539A RS P20110539 A RSP20110539 A RS P20110539A RS 52057 B2 RS52057 B2 RS 52057B2
Authority
RS
Serbia
Prior art keywords
pramipexol
formulation
release tablet
tablet containing
continued release
Prior art date
Application number
RS20110539A
Other languages
English (en)
Inventor
Thomas Friedl
Wolfram Eisenreich
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34926161&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RS52057(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of RS52057B publication Critical patent/RS52057B/sr
Publication of RS52057B2 publication Critical patent/RS52057B2/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RS20110539A 2004-08-13 2005-07-25 Formulacija tablete sa produženim oslobađanjem koja sadrži pramipeksol ili njegovu farmaceutski prihvatljivu so RS52057B2 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04019248 2004-08-13
EP05763065.9A EP1789021B2 (en) 2004-08-13 2005-07-25 Extended release tablet formulation containing pramipexole or a pharmaceutically acceptable salt thereof
PCT/EP2005/053610 WO2006015944A2 (en) 2004-08-13 2005-07-25 Extended release tablet formulation containing pramipexole or a pharmaceutically acceptable salt thereof

Publications (2)

Publication Number Publication Date
RS52057B RS52057B (sr) 2012-04-30
RS52057B2 true RS52057B2 (sr) 2018-03-30

Family

ID=34926161

Family Applications (2)

Application Number Title Priority Date Filing Date
RS20100557A RS51527B2 (sr) 2004-08-13 2005-07-25 Tabletna formulacija sa produženim otpuštanjem koja sadrži pramipeksol ili njegovu farmaceutski prihvatljivu so, postupak za proizvodnju iste i njena primena
RS20110539A RS52057B2 (sr) 2004-08-13 2005-07-25 Formulacija tablete sa produženim oslobađanjem koja sadrži pramipeksol ili njegovu farmaceutski prihvatljivu so

Family Applications Before (1)

Application Number Title Priority Date Filing Date
RS20100557A RS51527B2 (sr) 2004-08-13 2005-07-25 Tabletna formulacija sa produženim otpuštanjem koja sadrži pramipeksol ili njegovu farmaceutski prihvatljivu so, postupak za proizvodnju iste i njena primena

Country Status (33)

Country Link
US (6) US20060051417A1 (sr)
EP (6) EP2135602A1 (sr)
JP (5) JP4785847B2 (sr)
KR (2) KR101052436B1 (sr)
CN (4) CN101005830B (sr)
AR (1) AR050602A1 (sr)
AT (2) ATE532503T1 (sr)
AU (3) AU2005271194B2 (sr)
BR (2) BRPI0513846A (sr)
CA (3) CA2572729C (sr)
CY (2) CY1111713T1 (sr)
DE (1) DE602005024570D1 (sr)
DK (2) DK1789021T4 (sr)
EA (4) EA200900930A1 (sr)
EC (2) ECSP077241A (sr)
ES (2) ES2377214T3 (sr)
HK (2) HK1104974A1 (sr)
HR (2) HRP20100682T4 (sr)
IL (3) IL181283A (sr)
ME (2) ME01442B (sr)
MX (2) MX2007001706A (sr)
NO (2) NO342453B1 (sr)
NZ (3) NZ589267A (sr)
PH (1) PH12012501282A1 (sr)
PL (2) PL1781260T5 (sr)
PT (2) PT1781260E (sr)
RS (2) RS51527B2 (sr)
SG (1) SG148996A1 (sr)
SI (2) SI1789021T1 (sr)
TW (2) TWI347199B (sr)
UA (3) UA93608C2 (sr)
WO (2) WO2006015942A1 (sr)
ZA (2) ZA200700086B (sr)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020035107A1 (en) 2000-06-20 2002-03-21 Stefan Henke Highly concentrated stable meloxicam solutions
PA8578501A1 (es) * 2002-07-25 2005-02-04 Pharmacia Corp Forma de dosificacion una vez al dia de pramipexol
US20050226926A1 (en) 2002-07-25 2005-10-13 Pfizer Inc Sustained-release tablet composition of pramipexole
US8992980B2 (en) 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
EP1568369A1 (en) 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the treatment of respiratory diseases in pigs
EA200700388A1 (ru) * 2004-08-13 2007-08-31 Бёрингер Ингельхайм Интернациональ Гмбх Композиция пеллеты пролонгированного высвобождения, содержащая прамипексол или его фармацевтически приемлемую соль, способ её изготовления и её применение
PT1781260E (pt) 2004-08-13 2010-12-20 Boehringer Ingelheim Int Formulação em comprimido de libertação prolongada contendo pramipexole ou um seu sal farmaceuticamente aceitável, um método para a preparação do mesmo e sua utilização
ES2539969T3 (es) * 2004-08-25 2015-07-07 Essentialis, Inc. Formulaciones farmacéuticas de activadores del canal de potasio de ATP y usos de las mismas
US20070104787A1 (en) * 2005-11-04 2007-05-10 Posey-Dowty Jessica D Carboxyalkyl cellulose esters for sustained delivery of pharmaceutically active substances
WO2007090883A1 (en) * 2006-02-10 2007-08-16 Boehringer Ingelheim International Gmbh Extended release formulation
US20090041844A1 (en) * 2006-02-10 2009-02-12 Boehringer Ingelheim International Gmbh Modified Release Formulation
WO2007090882A2 (en) * 2006-02-10 2007-08-16 Boehringer Ingelheim International Gmbh Pharmaceutical extended release compositions comprising pramipexole
US8518926B2 (en) 2006-04-10 2013-08-27 Knopp Neurosciences, Inc. Compositions and methods of using (R)-pramipexole
FR2900823B1 (fr) * 2006-05-15 2009-02-13 Bioprojet Soc Civ Ile Nouvelle forme d'administration du racecadotril.
CA2652251A1 (en) 2006-05-16 2007-11-29 Knopp Neurosciences, Inc. Compositions of r(+) and s(-) pramipexole and methods for using the same
WO2008009664A2 (en) * 2006-07-19 2008-01-24 Boehringer Ingelheim International Gmbh Treatment of pain
KR20090045943A (ko) * 2006-08-24 2009-05-08 베링거 잉겔하임 파르마 게엠베하 운트 코 카게 저장 안정성이 높은 프라미펙솔 디하이드로클로라이드 정제의 제조방법
US20080254118A1 (en) * 2007-04-11 2008-10-16 Hans-Werner Wernersbach Process for preparing pramipexole dihydrochloride tablets
US8524695B2 (en) 2006-12-14 2013-09-03 Knopp Neurosciences, Inc. Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same
US8519148B2 (en) 2007-03-14 2013-08-27 Knopp Neurosciences, Inc. Synthesis of chirally purified substituted benzothiazole diamines
US20080254117A1 (en) * 2007-04-10 2008-10-16 Noel Cotton Process for preparing pramipexole dihydrochloride tablets
EP2150239A1 (en) * 2007-04-24 2010-02-10 Boehringer Ingelheim International GmbH Combination with an extended release tablet formulation containing pramipexole or a pharmaceutically acceptable salt thereof
EP2291178A4 (en) * 2008-06-09 2013-07-24 Supernus Pharmaceuticals Inc PRAMIPEXOL FORMULATIONS WITH CONTROLLED RELEASE
EP2334185A4 (en) 2008-08-19 2011-09-21 Knopp Neurosciences Inc COMPOSITIONS AND METHODS FOR USE OF (R) -PRAMIPEXOL
US20100159001A1 (en) * 2008-12-19 2010-06-24 Cardinal John R Extended-Release Pharmaceutical Formulations
MX2012000096A (es) * 2009-07-02 2012-04-02 Supernus Pharmaceuticals Inc Un metodo de tratamiento de un trastorno neurologico.
WO2011086182A2 (en) * 2010-01-18 2011-07-21 Synthon Bv Pramipexole extended release tablets
US20120059013A1 (en) * 2010-03-09 2012-03-08 Boehringer Ingelheim International Gmbh Method of treating early morning akinesia in subjects having parkinson's disease
TR201001862A1 (tr) * 2010-03-11 2011-10-21 Sanovel �La� San.Ve T�C.A.�. Kontrollü salım gerçekleştiren pramipeksol formülasyonları.
KR101406265B1 (ko) * 2010-03-17 2014-06-12 영진약품공업주식회사 안정성이 개선된 프라미펙솔을 함유하는 약제학적 조성물 및 이의 제조방법
US20130209553A1 (en) 2010-04-15 2013-08-15 Cadila Healthcare Limited Extended release pharmaceutical compositions of pramipexole
EP2380560A1 (de) * 2010-04-22 2011-10-26 ratiopharm GmbH Pramipexol enthaltende Matrixtablette
US9795568B2 (en) 2010-05-05 2017-10-24 Boehringer Ingelheim Vetmedica Gmbh Low concentration meloxicam tablets
WO2011148243A1 (en) 2010-05-24 2011-12-01 Lupin Limited Extended release formulation of pramipexole
WO2013034173A1 (en) 2011-09-06 2013-03-14 Synthon Bv Pramipexole extended release tablets
KR101439635B1 (ko) * 2011-11-01 2014-09-11 대원제약주식회사 안정성이 향상된 엔테카비어를 함유하는 약학적 조성물 및 그 제조방법
CN102406626B (zh) * 2011-12-02 2013-08-28 深圳海王药业有限公司 盐酸普拉克索缓释片剂及其制备方法
US9512096B2 (en) 2011-12-22 2016-12-06 Knopp Biosciences, LLP Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds
CA2862469A1 (en) * 2012-01-23 2013-08-01 Ranbaxy Laboratories Limited In-situ multilayered tablet technology
CN102836137A (zh) * 2012-09-21 2012-12-26 山东齐都药业有限公司 一种高含量均匀度的盐酸普拉克索缓释片剂及其制备方法
EP2732812A1 (de) 2012-11-15 2014-05-21 Aristo Pharma GmbH Pramipexol-Retardtablettenformulierung
CN103058953B (zh) * 2012-11-22 2015-03-25 刘炜 用于治疗神经疾病的四氢苯并噻唑衍生物
CN102988319B (zh) * 2012-12-10 2014-10-08 成都欣捷高新技术开发有限公司 一种ⅲ晶型盐酸普拉克索片剂及其制备方法
CN103040781B (zh) * 2013-01-04 2014-07-16 杭州朱养心药业有限公司 盐酸普拉克索片剂药物组合物及其制备方法
US9662313B2 (en) 2013-02-28 2017-05-30 Knopp Biosciences Llc Compositions and methods for treating amyotrophic lateral sclerosis in responders
CN104161735A (zh) * 2013-05-19 2014-11-26 成都康弘药业集团股份有限公司 一种含有盐酸普拉克索的缓释制剂及其制备方法
HUE054185T2 (hu) 2013-07-12 2021-08-30 Knopp Biosciences Llc Eozinofilek és/vagy bazofilek megemelkedett szintjének kezelése
US9468630B2 (en) 2013-07-12 2016-10-18 Knopp Biosciences Llc Compositions and methods for treating conditions related to increased eosinophils
WO2015023786A1 (en) 2013-08-13 2015-02-19 Knopp Biosciences Llc Compositions and methods for treating plasma cell disorders and b-cell prolymphocytic disorders
US9763918B2 (en) 2013-08-13 2017-09-19 Knopp Biosciences Llc Compositions and methods for treating chronic urticaria
CN103520128B (zh) 2013-10-12 2018-08-21 石家庄杏林锐步医药科技股份有限公司 一种普拉克索的缓释片剂、制备方法及其用途
CN105456216B (zh) * 2014-08-18 2019-11-05 江苏神龙药业股份有限公司 盐酸普拉克索缓释片剂组合物及其制备方法
JP2016113441A (ja) * 2014-10-27 2016-06-23 大原薬品工業株式会社 プラミペキソール二塩酸塩一水和物を含む放出が延長された錠剤
CN105796519A (zh) * 2014-12-30 2016-07-27 浙江京新药业股份有限公司 盐酸普拉克索缓释片及其制备方法
CN104606162B (zh) * 2015-01-07 2017-03-29 海南康虹医药科技开发有限公司 一种盐酸普拉克索缓释制剂及其制备方法
JP6366547B2 (ja) * 2015-08-03 2018-08-01 大原薬品工業株式会社 光安定性が向上した、プラミペキソール製剤包装体
CN105380917B (zh) * 2015-08-24 2019-01-15 江苏神华药业有限公司 一种盐酸普拉克索缓释片及其制备方法
CN106983729B (zh) * 2016-01-21 2021-02-26 北京北大维信生物科技有限公司 普拉克索缓释片及制备方法
CN107951853B (zh) * 2016-10-17 2022-04-08 海思科制药(眉山)有限公司 一种盐酸普拉克索缓释药物组合物及其制备方法
CN108785263B (zh) * 2017-04-26 2021-06-29 江苏恒瑞医药股份有限公司 普拉克索或其药用盐的固体药物组合物及其制备方法
DE18837223T1 (de) 2017-07-26 2020-03-26 Tgx Soft Chew, Llc Stärkefreier weicher kausnack für veterinärmedizinische anwendungen
CN111212640A (zh) 2017-08-17 2020-05-29 顾自强 单胺抗帕金森药物的双羟萘酸盐、其制备方法及其用途
CN109966256B (zh) * 2017-12-28 2022-08-02 北京北大维信生物科技有限公司 一种普拉克索缓释药物组合物、其制备方法及用途
CN108159007B (zh) * 2017-12-29 2021-04-16 成都百裕制药股份有限公司 一种盐酸普拉克索缓释制剂及其制备方法
WO2019207606A1 (en) * 2018-04-27 2019-10-31 Rubicon Research Private Limited Extended release compositions and process for preparation
CN112704668B (zh) * 2021-01-12 2022-09-30 石药集团中奇制药技术（石家庄）有限公司 一种盐酸普拉克索缓释组合物
CN112716908A (zh) * 2021-02-03 2021-04-30 上海雅本化学有限公司 一种普拉克索的制备工艺
CN113876729B (zh) * 2021-11-11 2023-05-30 南通联亚药业股份有限公司 一种盐酸普拉克索缓释片剂及其制备方法
CN114869854A (zh) * 2022-04-18 2022-08-09 华裕(无锡)制药有限公司 一种生物等效性高的盐酸普拉克索缓释片及其制备方法

Family Cites Families (123)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2887440A (en) 1957-08-12 1959-05-19 Dow Chemical Co Enteric coating
US3065143A (en) 1960-04-19 1962-11-20 Richardson Merrell Inc Sustained release tablet
NL265428A (sr) * 1960-06-06
US3458622A (en) 1967-04-07 1969-07-29 Squibb & Sons Inc Controlled release tablet
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
JPS58403B2 (ja) 1975-07-24 1983-01-06 武田薬品工業株式会社 Ｌ− アスコルビンサンセイザイノ セイゾウホウ
US4140755A (en) 1976-02-13 1979-02-20 Hoffmann-La Roche Inc. Sustained release tablet formulations
US4167558A (en) 1976-02-13 1979-09-11 Hoffmann-La Roche Inc. Novel sustained release tablet formulations
CH649215A5 (de) 1981-04-29 1985-05-15 Hoffmann La Roche Pharmazeutische praeparate.
SE8103843L (sv) 1981-06-18 1982-12-19 Astra Laekemedel Ab Farmaceutisk mixtur
US4424235A (en) 1981-09-14 1984-01-03 Hoffmann-La Roche Inc. Hydrodynamically balanced controlled release compositions containing L-dopa and a decarboxylase inhibitor
US4389393A (en) 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
DE3572485D1 (en) 1984-12-22 1989-09-28 Thomae Gmbh Dr K Tetrahydro-benzothiazoles, their production and their use as intermediates or drugs
US4738851A (en) * 1985-09-27 1988-04-19 University Of Iowa Research Foundation, Inc. Controlled release ophthalmic gel formulation
US4666612A (en) * 1986-03-17 1987-05-19 Kerr-Mcgee Chemical Corporation Method for recovering a wood preservative from waste sludges
US4772473A (en) * 1986-06-16 1988-09-20 Norwich Eaton Pharmaceuticals, Inc. Nitrofurantoin dosage form
US4709712A (en) 1986-10-22 1987-12-01 Dermatalogical Products Of Texas Polycarboxylic acid polymer gels as protective agents
US4968508A (en) 1987-02-27 1990-11-06 Eli Lilly And Company Sustained release matrix
US4789549A (en) * 1987-03-09 1988-12-06 Warner-Lambert Company Sustained release dosage forms
US4859470A (en) 1988-06-02 1989-08-22 Alza Corporation Dosage form for delivering diltiazem
GB8828020D0 (en) * 1988-12-01 1989-01-05 Unilever Plc Topical composition
US5026559A (en) * 1989-04-03 1991-06-25 Kinaform Technology, Inc. Sustained-release pharmaceutical preparation
US5007790A (en) 1989-04-11 1991-04-16 Depomed Systems, Inc. Sustained-release oral drug dosage form
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
US5273975A (en) 1989-06-09 1993-12-28 The Upjohn Company Heterocyclic amines having central nervous system activity
DE69016430T2 (de) 1989-06-09 1995-06-01 Upjohn Co Heterozyklische amine mit zns-wirksamkeit.
FR2653337B1 (fr) 1989-10-23 1992-02-07 Dow Corning Sa Element a liberation prolongee et procede pour le fabriquer.
IE82916B1 (en) * 1990-11-02 2003-06-11 Elan Corp Plc Formulations and their use in the treatment of neurological diseases
JPH04234812A (ja) 1990-03-16 1992-08-24 Yamanouchi Pharmaceut Co Ltd 持続性製剤用顆粒
GB9015822D0 (en) * 1990-07-18 1990-09-05 Beecham Group Plc Compositions
US5681585A (en) * 1991-12-24 1997-10-28 Euro-Celtique, S.A. Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
US5472712A (en) 1991-12-24 1995-12-05 Euroceltique, S.A. Controlled-release formulations coated with aqueous dispersions of ethylcellulose
US5656296A (en) 1992-04-29 1997-08-12 Warner-Lambert Company Dual control sustained release drug delivery systems and methods for preparing same
US5661171A (en) * 1992-07-02 1997-08-26 Oramed, Inc. Controlled release pilocarpine delivery system
ES2179829T3 (es) 1992-09-18 2003-02-01 Yamanouchi Pharma Co Ltd Preparacion de hidrogel de liberacion prolongada.
DE4241013A1 (de) * 1992-12-05 1994-06-09 Boehringer Ingelheim Kg Verwendung von 2-Amino-6-n-propyl-amino-4,5,6,7-tetrahydrobenzothiazol als Arzneimittel mit antidepressiver Wirkung
US5431920A (en) 1993-09-21 1995-07-11 Merck Frosst, Canada, Inc. Enteric coated oral compositions containing bisphosphonic acid antihypercalcemic agents
US5458887A (en) 1994-03-02 1995-10-17 Andrx Pharmaceuticals, Inc. Controlled release tablet formulation
DE4432757A1 (de) * 1994-09-14 1996-03-21 Boehringer Mannheim Gmbh Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung
WO1997004752A1 (en) * 1995-07-26 1997-02-13 Duramed Pharmaceuticals, Inc. Pharmaceutical compositions of conjugated estrogens and methods for their use
US5846971A (en) * 1996-06-28 1998-12-08 Schering Corporation Oral antifungal composition
JPH1017497A (ja) * 1996-07-02 1998-01-20 Takeda Chem Ind Ltd 徐放性製剤およびその製造方法
GB9619074D0 (en) 1996-09-12 1996-10-23 Smithkline Beecham Plc Composition
AU729529B2 (en) 1997-06-06 2001-02-01 Depomed, Inc. Gastric-retentive oral drug dosage forms for controlled release of highly soluble drugs
EA002482B1 (ru) 1997-07-01 2002-06-27 Пфайзер Инк. Соли сертралина и лекарственные формы с длительным высвобождением сертралина
ATE322892T1 (de) 1997-07-02 2006-04-15 Euro Celtique Sa Stabilisierte tramadol formulierungen mit verzögerter freisetzung
US5895663A (en) * 1997-07-31 1999-04-20 L. Perrigo Company Pseudoephedrine hydrochloride extended-release tablets
CA2211778A1 (en) 1997-08-14 1999-02-14 Francois Carriere Preparation of pregelatinized high amylose starch and debranched starch useful as an excipient for controlled release of active agents
US6624200B2 (en) 1998-08-25 2003-09-23 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US6248358B1 (en) 1998-08-25 2001-06-19 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets and methods of making and using the same
US7153845B2 (en) 1998-08-25 2006-12-26 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
DE69819748T2 (de) 1997-09-12 2004-09-30 Columbia Laboratories (Bermuda) Ltd. Arzneimittel zur behandlung von dysmenorrhöe und verfrühten wehen
NZ503464A (en) 1997-09-29 2002-05-31 Inhale Therapeutic Syst Perforated microparticles containing a bioactive agent for pulmonary delivery
US6197339B1 (en) 1997-09-30 2001-03-06 Pharmacia & Upjohn Company Sustained release tablet formulation to treat Parkinson's disease
US6056977A (en) 1997-10-15 2000-05-02 Edward Mendell Co., Inc. Once-a-day controlled release sulfonylurea formulation
US20020013304A1 (en) * 1997-10-28 2002-01-31 Wilson Leland F. As-needed administration of an androgenic agent to enhance female sexual desire and responsiveness
US20020054911A1 (en) * 2000-05-11 2002-05-09 Boehringer Mannheim Pharmaceutical Corporation-Sm Ithkline Beckman Corporation, Limited Partnershi Novel oral dosage form for carvedilol
FR2772615B1 (fr) * 1997-12-23 2002-06-14 Lipha Comprime multicouche pour la liberation instantanee puis prolongee de substances actives
GB9802201D0 (en) 1998-02-03 1998-04-01 Cerestar Holding Bv Free-flowable directly compressible starch as binder,disintegrant and filler for compresion tablets and hard gelatine capsules
NZ505807A (en) 1998-03-11 2003-01-31 Smithkline Beecham Corp Controlled release oral dosage form containing [R-(Z)]-alpha-(methoxyimino)-alpha-(1-azabicyclo [2.2.2]oct-3-yl)acetonitrile monohydrochloride; useful for the treatment or prophylaxis of dementia
WO1999059563A2 (en) 1998-05-15 1999-11-25 Pharmacia & Upjohn Company Cabergoline and pramipexole for treating cns diseases, especially parkinson's disease
GB9812426D0 (en) 1998-06-10 1998-08-05 Reckitt & Colmann Prod Ltd Improvements in or relating to organic compositions
US6312728B1 (en) 1998-07-07 2001-11-06 Cascade Development, Inc. Sustained release pharmaceutical preparation
TW407058B (en) 1998-07-17 2000-10-01 Dev Center Biotechnology Oral cisapride dosage forms with an extended duration
US20010055613A1 (en) 1998-10-21 2001-12-27 Beth A. Burnside Oral pulsed dose drug delivery system
US6270805B1 (en) 1998-11-06 2001-08-07 Andrx Pharmaceuticals, Inc. Two pellet controlled release formulation for water soluble drugs which contains an alkaline metal stearate
DE19906290A1 (de) 1999-02-15 2000-08-17 Falk Pharma Gmbh Arzneimittel zur Behandlung bzw. Prävention von Darmkrebs
AR028986A1 (es) * 1999-02-23 2003-06-04 Smithkline Beecham Corp USO DE UN INHIBIDOR DE PDE4 EN LA FABRICACIoN DE UNA PREPARACIoN DE LIBERACIoN CONTROLADA; FORMULACION DE LIBERACION CONTROLADA PARA EL TRATAMIENTO DE COPD, UN PROCEDIMIENTO PARA SU PREPARACIoN Y COMPOSICIoN FARMACÉUTICA
US7374779B2 (en) * 1999-02-26 2008-05-20 Lipocine, Inc. Pharmaceutical formulations and systems for improved absorption and multistage release of active agents
CN1208090C (zh) 1999-03-31 2005-06-29 詹森药业有限公司 在控制释放制剂中的预胶凝淀粉
DE19927688A1 (de) 1999-06-17 2000-12-21 Gruenenthal Gmbh Mehrschichttablette zur Verabreichung einer fixen Kombination von Tramadol und Diclofenac
EA200801805A1 (ru) 1999-07-01 2008-12-30 Фармация Энд Апджон Компани Высокоселективные ингибиторы обратного захвата норэпинефрина и способы их применения
CA2416233A1 (en) * 1999-07-13 2001-01-18 Alpha Research Group, Llc Compositions and methods for the treatment of parkinson's disease
AU5060499A (en) 1999-08-04 2001-03-05 Ranbaxy Laboratories Limited Hydrodynamically balanced oral drug delivery system
US6387403B1 (en) 1999-09-15 2002-05-14 Alza Corporation Dosage forms and methods for providing effective reboxetine therapy with once-a-day dosing
GB9923045D0 (en) 1999-09-29 1999-12-01 Novartis Ag New oral formulations
WO2001022820A1 (en) 1999-09-30 2001-04-05 The General Hospital Corporation Use of pramipexole as a treatment for cocaine craving
WO2001028516A2 (en) * 1999-10-19 2001-04-26 Nps Pharmaceuticals, Inc. Sustained-release formulations for treating cns-mediated disorders
US20030180352A1 (en) 1999-11-23 2003-09-25 Patel Mahesh V. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
PL355391A1 (en) 1999-12-22 2004-04-19 Pharmacia Corporation Sustained-release formulation of a cyclooxygenase-2 inhibitor
CA2332691C (en) 2000-01-27 2007-11-27 The York Group, Inc. Death care merchandising system
PE20011074A1 (es) * 2000-02-23 2001-10-04 Upjohn Co Uso de pramipexol en el tratamiento de trastornos de adiccion
WO2001062236A2 (en) 2000-02-24 2001-08-30 Pharmacia & Upjohn Company New drug combinations comprising a norepinephrine reuptake inhibitor and an antimuscarinic agent
US6955821B2 (en) * 2000-04-28 2005-10-18 Adams Laboratories, Inc. Sustained release formulations of guaifenesin and additional drug ingredients
US6372252B1 (en) * 2000-04-28 2002-04-16 Adams Laboratories, Inc. Guaifenesin sustained release formulation and tablets
US6277875B1 (en) * 2000-07-17 2001-08-21 Andrew J. Holman Use of dopamine D2/D3 receptor agonists to treat fibromyalgia
CA2418915A1 (en) * 2000-08-08 2002-02-14 Teva Pharmaceutical Industries Ltd. Stable pergolide mesylate and process for making same
ES2187249B1 (es) 2000-09-18 2004-09-16 Synthon Bv Procedimiento para la preparacion de 2-amino-6-(alquil)amino-4,5,6,7-tetrahidrobenzotiazoles.
SE0004671D0 (sv) * 2000-12-15 2000-12-15 Amarin Dev Ab Pharmaceutical formulation
US6287599B1 (en) * 2000-12-20 2001-09-11 Shire Laboratories, Inc. Sustained release pharmaceutical dosage forms with minimized pH dependent dissolution profiles
US20030022875A1 (en) * 2001-07-27 2003-01-30 Wilson Leland F. As-needed administration of orally active androgenic agents to enhance female sexual desire and responsiveness
US20030032661A1 (en) * 2001-08-02 2003-02-13 Boehringer Ingelheim Pharma Kg Pramipexole as an anticonvulsant
DE10138275A1 (de) 2001-08-10 2003-02-27 Boehringer Ingelheim Pharma Verbindungen zur Beseitigung der Anhedonie
JP2005516020A (ja) 2001-12-20 2005-06-02 ファルマシア・コーポレーション ゼロ次持続放出剤形およびその製造方法
KR20040091100A (ko) * 2002-03-04 2004-10-27 소시에떼 더 콘세이유 더 레세르세 에 다플리까띠옹 시엔띠피끄, 에스.아.에스. 운반체 펩타이드를 함유하는 서방형 의약 조성물
EP1639997A1 (en) 2002-04-05 2006-03-29 Euro-Celtique S.A. Matrix for sustained, invariant and independant release of active compounds
IL164438A0 (en) * 2002-04-15 2005-12-18 Adams Lab Inc Sustaubed release of guaifenesin combination drugs
US20030215498A1 (en) * 2002-05-17 2003-11-20 Harland Ronald S. Rapidly disintegrating comressed tablets comprising biologically active compounds
WO2003103603A2 (en) * 2002-06-10 2003-12-18 Wyeth Novel formate salt of o-desmethyl-venlafaxine
BR0312206A (pt) 2002-06-27 2005-04-12 Cilag Ag Formulações de pélete esférico
JP4478413B2 (ja) * 2002-07-11 2010-06-09 武田薬品工業株式会社 被覆製剤の製造法
FR2842734A1 (fr) * 2002-07-24 2004-01-30 Ethypharm Sa Procede pour diminuer la variabilite de la biodisponibilite d'un medicament a administration orale et compositions pharmaceutiques a administration orale
JP2005538105A (ja) * 2002-07-25 2005-12-15 ファルマシア・コーポレーション 水不溶性ポリマーおよび水溶性の小孔形成物質からなる２層により被覆された固体剤形の製造方法
US20050226926A1 (en) 2002-07-25 2005-10-13 Pfizer Inc Sustained-release tablet composition of pramipexole
PA8578501A1 (es) * 2002-07-25 2005-02-04 Pharmacia Corp Forma de dosificacion una vez al dia de pramipexol
MY136318A (en) 2002-07-25 2008-09-30 Pharmacia Corp Sustained-release tablet composition
US20040121010A1 (en) * 2002-10-25 2004-06-24 Collegium Pharmaceutical, Inc. Pulsatile release compositions of milnacipran
AU2003224467A1 (en) * 2003-03-11 2004-09-30 Korea United Pharm, Inc. Process for the preparing of hardcapsule formulation containing lansoprazole
BRPI0408999A (pt) 2003-04-04 2006-03-28 Pharmacia Corp comprimidos prensados de multiparticulados de liberação oral prolongada
US20050020589A1 (en) 2003-06-18 2005-01-27 Pfizer Inc. Sustained-release tablet composition comprising a dopamine receptor agonist
EA200700388A1 (ru) * 2004-08-13 2007-08-31 Бёрингер Ингельхайм Интернациональ Гмбх Композиция пеллеты пролонгированного высвобождения, содержащая прамипексол или его фармацевтически приемлемую соль, способ её изготовления и её применение
PT1781260E (pt) * 2004-08-13 2010-12-20 Boehringer Ingelheim Int Formulação em comprimido de libertação prolongada contendo pramipexole ou um seu sal farmaceuticamente aceitável, um método para a preparação do mesmo e sua utilização
WO2006046256A1 (en) 2004-10-27 2006-05-04 Alembic Limited Extended release formulation of pramipexole dihydrochloride
WO2007002518A1 (en) 2005-06-23 2007-01-04 Spherics, Inc. Delayed release or extended-delayed release dosage forms of pramipexole
CA2613631A1 (en) 2005-06-23 2007-01-04 Spherics, Inc. Improved dosage forms for movement disorder treatment
AU2006279643B2 (en) 2005-08-15 2010-06-17 University Of Virginia Patent Foundation Neurorestoration with R(+) pramipexole
WO2007054976A2 (en) 2005-11-08 2007-05-18 Panacea Biotec Ltd. Lipid based controlled release pharmaceutical composition
WO2007090882A2 (en) 2006-02-10 2007-08-16 Boehringer Ingelheim International Gmbh Pharmaceutical extended release compositions comprising pramipexole
WO2007090883A1 (en) 2006-02-10 2007-08-16 Boehringer Ingelheim International Gmbh Extended release formulation
US20090041844A1 (en) 2006-02-10 2009-02-12 Boehringer Ingelheim International Gmbh Modified Release Formulation
EP1886665A1 (en) 2006-08-01 2008-02-13 Boehringer Ingelheim Pharma GmbH & Co. KG Gastro retentive delivery system
CL2007002214A1 (es) * 2006-08-14 2008-03-07 Boehringer Ingelheim Int Composicion farmaceutica en la forma de comprimido, donde al menos la longitud del comprimido en el estado anterior de la aplicacion es al menos 7/12 del diametro pilorico del paciente y despues de ingerirlo en estado alimentado, la longitud del comp
AR062321A1 (es) * 2006-08-25 2008-10-29 Boehringer Ingelheim Int Sistema de liberacion controlada y metodo para fabricarlo

Also Published As

Publication number Publication date
KR20070046172A (ko) 2007-05-02
HK1104973A1 (en) 2008-02-01
MX2007001765A (es) 2007-04-20
JP2008509194A (ja) 2008-03-27
CA2736965A1 (en) 2006-02-16
EP1789021A2 (en) 2007-05-30
ME01442B (me) 2013-12-20
AU2005271192B2 (en) 2011-11-17
PH12012501282A1 (en) 2019-03-22
HRP20120068T4 (hr) 2015-02-13
HRP20100682T1 (en) 2011-01-31
US20060051417A1 (en) 2006-03-09
SI1789021T1 (sl) 2012-02-29
EP2286801A3 (en) 2012-05-09
CA2572729C (en) 2011-06-21
NO20070719L (no) 2007-03-02
AU2005271192A1 (en) 2006-02-16
EA200700132A1 (ru) 2007-08-31
JP2011126916A (ja) 2011-06-30
CA2572864C (en) 2014-02-11
EP2135602A1 (en) 2009-12-23
SI1781260T2 (sl) 2014-08-29
IL181283A0 (en) 2007-07-04
AR050602A1 (es) 2006-11-08
RS51527B2 (sr) 2018-02-28
ES2377214T3 (es) 2012-03-23
CA2572729A1 (en) 2006-02-16
CA2572864A1 (en) 2006-02-16
NZ553587A (en) 2010-12-24
NO342453B1 (no) 2018-05-22
ZA200700085B (en) 2008-02-27
EP1789021B1 (en) 2011-11-09
US20090182024A1 (en) 2009-07-16
CN101884626A (zh) 2010-11-17
WO2006015942A1 (en) 2006-02-16
ZA200700086B (en) 2008-02-27
TW200618821A (en) 2006-06-16
EP2286801A2 (en) 2011-02-23
DK1789021T4 (da) 2014-11-10
ECSP077241A (es) 2007-03-29
US20140335175A1 (en) 2014-11-13
HRP20120068T1 (en) 2012-02-29
JP4757872B2 (ja) 2011-08-24
AU2005271194A1 (en) 2006-02-16
CN101005831B (zh) 2010-11-10
CN101005830B (zh) 2010-09-29
DK1781260T3 (da) 2011-02-21
US7695734B2 (en) 2010-04-13
KR101406767B1 (ko) 2014-06-20
US8377977B2 (en) 2013-02-19
UA93608C2 (ru) 2011-02-25
NZ589267A (en) 2012-06-29
CN101005830A (zh) 2007-07-25
WO2006015944A3 (en) 2007-02-08
PL1781260T5 (pl) 2014-09-30
TW201100126A (en) 2011-01-01
EP2368545A1 (en) 2011-09-28
PT1789021E (pt) 2011-12-22
UA86831C2 (uk) 2009-05-25
KR20070052300A (ko) 2007-05-21
RS51527B (sr) 2011-06-30
EA016850B1 (ru) 2012-08-30
AU2005271194B2 (en) 2011-11-24
US20090281153A1 (en) 2009-11-12
NO20070733L (no) 2007-03-06
CY1112268T1 (el) 2015-12-09
PT1781260E (pt) 2010-12-20
ME01316B (me) 2013-12-20
EP1781260B2 (en) 2014-04-02
EP1789021B2 (en) 2014-10-08
HRP20100682T4 (hr) 2014-08-01
DK1781260T4 (da) 2014-06-23
WO2006015944A2 (en) 2006-02-16
CN101849921A (zh) 2010-10-06
JP4785847B2 (ja) 2011-10-05
JP2011084577A (ja) 2011-04-28
JP2009102409A (ja) 2009-05-14
JP2008509192A (ja) 2008-03-27
US20130274300A1 (en) 2013-10-17
TWI347850B (en) 2011-09-01
SG148996A1 (en) 2009-01-29
CY1111713T1 (el) 2015-10-07
ECSP077242A (es) 2007-05-30
DE602005024570D1 (de) 2010-12-16
CA2736965C (en) 2014-02-18
PL1789021T3 (pl) 2012-04-30
UA89052C2 (ru) 2009-12-25
EP1781260A1 (en) 2007-05-09
PL1781260T3 (pl) 2011-04-29
SI1781260T1 (sl) 2011-02-28
EP2345407A1 (en) 2011-07-20
RS52057B (sr) 2012-04-30
ATE486588T1 (de) 2010-11-15
KR101052436B1 (ko) 2011-07-29
ES2355735T5 (es) 2014-06-27
EA015335B1 (ru) 2011-06-30
IL181282A (en) 2012-10-31
IL220313A0 (en) 2012-07-31
US20060198887A1 (en) 2006-09-07
EA201001083A1 (ru) 2011-08-30
IL181282A0 (en) 2007-07-04
MX2007001706A (es) 2007-04-12
IL181283A (en) 2013-12-31
TWI347199B (en) 2011-08-21
BRPI0513846A (pt) 2008-05-20
EP1781260B1 (en) 2010-11-03
EP1781260B9 (en) 2011-02-16
ES2355735T3 (es) 2011-03-30
EA200900930A1 (ru) 2009-12-30
DK1789021T3 (da) 2012-03-05
ATE532503T1 (de) 2011-11-15
HK1104974A1 (en) 2008-02-01
CN101005831A (zh) 2007-07-25
AU2011250676A1 (en) 2011-12-01
NZ553561A (en) 2010-12-24
BRPI0513847A (pt) 2008-05-20
EA200700201A1 (ru) 2007-08-31

Similar Documents

Publication Publication Date Title
RS52057B2 (sr) Formulacija tablete sa produženim oslobađanjem koja sadrži pramipeksol ili njegovu farmaceutski prihvatljivu so
HRP20181819T1 (hr) Formulacija krutog farmaceutskog oblika doziranja koja sadrži lopinavir
CY2017038I2 (el) Νεες φαρμακευτικες συνθεσεις που περιεχουν 4-(4-(3-(4-χλωρο-3-τριφθορομεθυλ-φαινυλ)-ουρειδο)-3-φθορο-φαινοξυ)-πυριδιν-2-καρβοξυλικο οξυ για thν θεραπευτικη αγωγη υπερπολλαπλασιαστικων διαταραχων
ITBO20050123A1 (it) Formulazioni farmaceutiche gastroresistenti contenenti rifaximina
ATE531358T1 (de) Selbsterhaltende wässrige pharmazeutische zusammensetzungen
NO20085415L (no) Farmasøytisk doseringsform inneholdende fenylefrin med vedvarende frigivelse
JP2007504142A5 (ja) Ｈｉｖプロテアーゼ阻害薬固体分散物を含む固体薬物剤形
ATE532788T1 (de) Pharmazeutische verbindungen
NO20043866L (no) Farmasoytisk formulering av IRESSA omfattende et vannopploselig cellulosederivat
IL181680A0 (en) Tablets with site time -controlled gastrointestinal release of active ingredient
DK2033629T3 (da) Fast farmaceutisk sammensætning omfattende valsartan
MA28526B1 (fr) Comprimes solubles contenant licarbazepine
ITMI20061117A1 (it) Una composizione farmaceutica per la somministrazione sublinguale di vaccini metodo per la sua preparazione e sui usi
DK2918286T3 (da) En farmaceutisk formulering
ATE511837T1 (de) Wässrige arzneimittelformulierung von 4-ä((4- carboxybutyl)-ä2-ä(4-phenethyl-benzyl)oxyü- phenethylüamino)methylübenzoesäure
ATE438381T1 (de) Zolpidemtabletten
DK1750765T3 (da) Farmaceutisk antimykobakteriesammensætning omfattende et antituberkulöst lægemiddel
NO20043633L (no) Oral doseringsform for kontrollert medikamentfrigivning
IS7290A (is) Lyfjasamsetningar sem innihalda risperidone
DE502004003170D1 (de) Schmelzformulierte, multipartikuläre orale darreichungsform enthaltend clavulansäure
UA10359S (uk) Пакування таблеток фармацевтичних «аскорбінова кислота»
DE602005005033D1 (de) Sprühgetrocknete pharmazeutische zusammensetzungen
TH0401004534B (th) กระบวนการสำหรับการเตรียมองค์ประกอบทางเภสัชกรรมของแข็งที่สามารถให้ทางปากได้(Process for the Preparation of A solid, Orally Adminnistrable Pharmaceutical Composition)
UA10045S (uk) Піктограма фармацевтичного засобу (в таблетках)
UA10054S (uk) Упаковка фармацевтичного засобу