PL3018132T3 - Skondensowane pochodne imidazolu użyteczne jako inhibitory ido - Google Patents

Skondensowane pochodne imidazolu użyteczne jako inhibitory ido

Info

Publication number: PL3018132T3
Authority: PL; Poland
Prior art keywords: imidazole derivatives; derivatives useful; ido inhibitors; fused imidazole; fused
Prior art date: 2011-04-15

Application number

PL15197593T

Other languages

English (en)

Inventor

Mario Mautino

Sanjeev Kumar

Jesse Waldo

Firoz Jaipuri

Tanay Kesharwani

Xiaoxia Zhang

Original Assignee

Newlink Genetics Corporation

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-04-15

Filing date

2012-04-12

Publication date

2018-05-30

2012-04-12 Application filed by Newlink Genetics Corporation filed Critical Newlink Genetics Corporation

2018-05-30 Publication of PL3018132T3 publication Critical patent/PL3018132T3/pl

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
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- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A61P37/04—Immunostimulants
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Immunology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Pulmonology (AREA)
Biotechnology (AREA)
Urology & Nephrology (AREA)
Biochemistry (AREA)
Tropical Medicine & Parasitology (AREA)
Endocrinology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Dermatology (AREA)
Transplantation (AREA)
AIDS & HIV (AREA)
Reproductive Health (AREA)
Hematology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Plural Heterocyclic Compounds (AREA)

PL15197593T 2011-04-15 2012-04-12 Skondensowane pochodne imidazolu użyteczne jako inhibitory ido PL3018132T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201161475788P	2011-04-15	2011-04-15
EP15197593.5A EP3018132B1 (en)	2011-04-15	2012-04-12	Fused imidazole derivatives useful as ido inhibitors
EP12715295.7A EP2697227B1 (en)	2011-04-15	2012-04-12	Fused imidazole derivatives useful as ido inhibitors

Publications (1)

Publication Number	Publication Date
PL3018132T3 true PL3018132T3 (pl)	2018-05-30

Family

ID=45976556

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PL15197593T PL3018132T3 (pl)	2011-04-15	2012-04-12	Skondensowane pochodne imidazolu użyteczne jako inhibitory ido
PL12715295.7T PL2697227T3 (pl)	2011-04-15	2012-04-12	Skondensowane pochodne imidazolu użyteczne jako inhibitory IDO

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PL12715295.7T PL2697227T3 (pl)	2011-04-15	2012-04-12	Skondensowane pochodne imidazolu użyteczne jako inhibitory IDO

Country Status (30)

Country	Link
US (5)	US9260434B2 (pl)
EP (3)	EP3348558A1 (pl)
JP (4)	JP2014511876A (pl)
KR (1)	KR102164443B1 (pl)
CN (2)	CN103547579B (pl)
AU (4)	AU2012242871C1 (pl)
BR (1)	BR112013026494A2 (pl)
CA (1)	CA2833296C (pl)
CL (1)	CL2013002990A1 (pl)
CO (1)	CO6862146A2 (pl)
CY (1)	CY1117440T1 (pl)
DK (2)	DK3018132T3 (pl)
ES (2)	ES2660831T3 (pl)
HK (1)	HK1256355A1 (pl)
HR (2)	HRP20160369T1 (pl)
HU (2)	HUE027316T2 (pl)
IL (3)	IL228862A (pl)
LT (1)	LT3018132T (pl)
ME (1)	ME02417B (pl)
MX (1)	MX340442B (pl)
NO (1)	NO2694640T3 (pl)
NZ (2)	NZ723271A (pl)
PE (2)	PE20141124A1 (pl)
PL (2)	PL3018132T3 (pl)
PT (1)	PT3018132T (pl)
RS (2)	RS56992B1 (pl)
RU (2)	RU2017107026A (pl)
SI (2)	SI3018132T1 (pl)
SM (1)	SMT201600130B (pl)
WO (1)	WO2012142237A1 (pl)

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Publication number	Publication date
CY1117440T1 (el)	2017-04-26
PL2697227T3 (pl)	2016-09-30
SMT201600130B (it)	2016-07-01
NZ723271A (en)	2018-03-23
HRP20160369T1 (hr)	2016-06-03
JP2015061877A (ja)	2015-04-02
IL241846A0 (en)	2015-11-30
AU2014274564A1 (en)	2015-01-22
RS54723B1 (en)	2016-08-31
CN105111210A (zh)	2015-12-02
IL228862A (en)	2015-10-29
AU2012242871B2 (en)	2014-09-11
US9260434B2 (en)	2016-02-16
PT3018132T (pt)	2018-03-09
IL228862A0 (en)	2013-12-31
RS56992B1 (sr)	2018-05-31
NZ616457A (en)	2015-05-29
MX2013012021A (es)	2014-07-10
ES2569665T3 (es)	2016-05-12
PE20181023A1 (es)	2018-06-27
US20180118753A1 (en)	2018-05-03
CN103547579A (zh)	2014-01-29
RU2613579C2 (ru)	2017-03-17
EP2697227A1 (en)	2014-02-19
AU2016277574B2 (en)	2018-04-19
US10233190B2 (en)	2019-03-19
ES2660831T3 (es)	2018-03-26
EP3018132B1 (en)	2017-12-13
IL246515B (en)	2018-08-30
BR112013026494A2 (pt)	2016-12-27
JP6145491B2 (ja)	2017-06-14
US20160002249A1 (en)	2016-01-07
NO2694640T3 (pl)	2018-03-17
HRP20180335T1 (hr)	2018-04-20
KR20140059167A (ko)	2014-05-15
HUE038586T2 (hu)	2018-10-29
HK1193822A1 (zh)	2014-10-03
US9388191B2 (en)	2016-07-12
HK1223371A1 (en)	2017-07-28
JP2014511876A (ja)	2014-05-19
HK1256355A1 (en)	2019-09-20
WO2012142237A1 (en)	2012-10-18
AU2014274564B2 (en)	2016-10-06
EP3348558A1 (en)	2018-07-18
DK2697227T3 (en)	2016-04-25
DK3018132T3 (en)	2018-03-12
JP2016029092A (ja)	2016-03-03
AU2012242871A1 (en)	2013-10-31
CL2013002990A1 (es)	2014-07-04
ME02417B (me)	2016-09-20
AU2018202706A1 (en)	2018-05-10
US20160362412A1 (en)	2016-12-15
US9850248B2 (en)	2017-12-26
AU2012242871C1 (en)	2017-02-02
IL241846A (en)	2016-06-30
SI2697227T1 (sl)	2016-06-30
AU2012242871A8 (en)	2013-11-21
CA2833296C (en)	2020-12-08
RU2017107026A (ru)	2019-01-23
MX340442B (es)	2016-07-08
US20190225618A1 (en)	2019-07-25
CN105111210B (zh)	2018-10-09
AU2016277574A1 (en)	2017-01-12
CO6862146A2 (es)	2014-02-10
JP2017149769A (ja)	2017-08-31
RU2013150811A (ru)	2015-05-20
JP5837673B2 (ja)	2015-12-24
CN103547579B (zh)	2017-02-15
WO2012142237A8 (en)	2012-11-22
RU2017107026A3 (pl)	2019-01-23
NZ708090A (en)	2016-12-23
KR102164443B1 (ko)	2020-10-12
PE20141124A1 (es)	2014-09-06
EP3018132A1 (en)	2016-05-11
SI3018132T1 (en)	2018-04-30
LT3018132T (lt)	2018-03-26
US20140066625A1 (en)	2014-03-06
CA2833296A1 (en)	2012-10-18
EP2697227B1 (en)	2016-02-03
HUE027316T2 (en)	2016-10-28

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