PL196354A1 - Sposob wytwarzania nowych,krystalicznych postaci chlorowodorku prazozyny - Google Patents
Sposob wytwarzania nowych,krystalicznych postaci chlorowodorku prazozynyInfo
- Publication number
- PL196354A1 PL196354A1 PL19635477A PL19635477A PL196354A1 PL 196354 A1 PL196354 A1 PL 196354A1 PL 19635477 A PL19635477 A PL 19635477A PL 19635477 A PL19635477 A PL 19635477A PL 196354 A1 PL196354 A1 PL 196354A1
- Authority
- PL
- Poland
- Prior art keywords
- prazosin
- chloride
- crystalline forms
- new crystalline
- making new
- Prior art date
Links
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- IENZQIKPVFGBNW-UHFFFAOYSA-N prazosin Chemical compound N=1C(N)=C2C=C(OC)C(OC)=CC2=NC=1N(CC1)CCN1C(=O)C1=CC=CO1 IENZQIKPVFGBNW-UHFFFAOYSA-N 0.000 title 1
- 229960001289 prazosin Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/662,937 US4092315A (en) | 1976-03-01 | 1976-03-01 | Novel crystalline forms of prazosin hydrochloride |
Publications (2)
Publication Number | Publication Date |
---|---|
PL196354A1 true PL196354A1 (pl) | 1978-02-27 |
PL105559B1 PL105559B1 (pl) | 1979-10-31 |
Family
ID=24659839
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL1977196354A PL105559B1 (pl) | 1976-03-01 | 1977-03-01 | Sposob wytwarzania nowej postaci polimorficznej chlorowodorku prazosinu |
Country Status (32)
Country | Link |
---|---|
US (1) | US4092315A (pl) |
JP (1) | JPS604188B2 (pl) |
AR (1) | AR210937A1 (pl) |
AU (1) | AU506937B2 (pl) |
BE (1) | BE851878A (pl) |
BG (1) | BG29724A3 (pl) |
CA (1) | CA1068269A (pl) |
CH (1) | CH618436A5 (pl) |
CS (1) | CS191332B2 (pl) |
DD (1) | DD129652A5 (pl) |
DE (1) | DE2708192C3 (pl) |
DK (1) | DK145858C (pl) |
ES (1) | ES8707447A1 (pl) |
FI (1) | FI62082C (pl) |
FR (1) | FR2372828A1 (pl) |
GB (1) | GB1538713A (pl) |
HK (1) | HK30881A (pl) |
HU (1) | HU173641B (pl) |
IE (1) | IE44522B1 (pl) |
IL (1) | IL51481A (pl) |
LU (1) | LU76868A1 (pl) |
MY (1) | MY8100271A (pl) |
NL (1) | NL169591C (pl) |
NO (1) | NO146499C (pl) |
NZ (1) | NZ183450A (pl) |
PL (1) | PL105559B1 (pl) |
PT (1) | PT66227B (pl) |
RO (1) | RO73095A (pl) |
SE (1) | SE423234B (pl) |
SU (1) | SU644387A3 (pl) |
YU (1) | YU41294B (pl) |
ZA (1) | ZA77918B (pl) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX5483E (es) * | 1977-08-04 | 1983-08-23 | Abbott Lab | Procedimiento para la preparacion del dihidrato clorhidrato de 1-(4-amino-6,7-dimetoxi-2-quinazolinil)-4-(2-tetrahidrofuroil)piperazina |
GB1591490A (en) * | 1977-08-04 | 1981-06-24 | Abbott Lab | 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride dihydrate |
US4197301A (en) * | 1978-10-16 | 1980-04-08 | Allergan Pharmaceuticals, Inc. | Topical ophthalmic use of Prazosin |
FI67699C (fi) * | 1979-01-31 | 1985-05-10 | Orion Yhtymae Oy | Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolinhydroklorid med blodtryckssaenkande verkan |
US4440769A (en) * | 1983-02-11 | 1984-04-03 | Abbott Laboratories | 2-(4-Phenylalkanoylpiperazin-1-yl) quinazoline compounds, pharmaceutical compositions and method of producing α1 antagonistic activity |
FI79107C (fi) * | 1984-06-25 | 1989-11-10 | Orion Yhtymae Oy | Foerfarande foer framstaellning av stabil -form av prazosinhydroklorid. |
US5322943A (en) * | 1985-09-12 | 1994-06-21 | The Upjohn Company | Piperazine compounds which are substituted |
US4601897A (en) * | 1985-11-06 | 1986-07-22 | Pfizer Inc. | Prazosin-pirbuterol combination for bronchodilation |
DE3683760D1 (de) * | 1986-03-21 | 1992-03-12 | Heumann Pharma Gmbh & Co | Kristalline, wasserfreie sigma -form von 2-(4-(2-furoyl-(2-piperazin)-1-yl)-4-amino-6,7-dimethoxychinazolinhydrochlorid und verfahren zu ihrer herstellung. |
US5110927A (en) * | 1987-12-31 | 1992-05-05 | The United States Of America As Represented By The Department Of Health And Human Services | Prazosin analog with increased selectivity and duration of action |
JP2652272B2 (ja) * | 1990-12-31 | 1997-09-10 | 住化ファインケム株式会社 | 1−(4−アミノ−6,7−ジメトキシ−2−キナゾリニル)−4−(2−テトラヒドロフロイル)ピペラジン塩酸塩の新規な結晶体および該結晶体の製造方法 |
GB9417310D0 (en) * | 1994-08-27 | 1994-10-19 | Pfizer Ltd | Therapeutic agents |
US5952003A (en) * | 1996-08-01 | 1999-09-14 | Novartis Corporation | Terazosin capsules |
EP0849264A1 (de) * | 1996-12-20 | 1998-06-24 | HEUMANN PHARMA GmbH | Neue polymorphe Form von doxazosinmesylat (Form I) |
EP0849266B8 (de) * | 1996-12-20 | 2007-10-03 | Heumann PCS GmbH | Neue polymorphe Form von Doxazosinmesylat (Form III) |
EP0849265A1 (de) * | 1996-12-20 | 1998-06-24 | HEUMANN PHARMA GmbH | Neue polymorphe Form von Doxazosin-Mesylat (Form II) |
EP3172377B1 (en) | 2014-07-21 | 2018-09-12 | KEIR Manufacturing, Inc. | Aerodynamic flyer bow |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3663706A (en) * | 1969-09-29 | 1972-05-16 | Pfizer | Use of 2,4-diaminoquinazolines as hypotensive agents |
-
1976
- 1976-03-01 US US05/662,937 patent/US4092315A/en not_active Expired - Lifetime
-
1977
- 1977-02-11 GB GB5756/77A patent/GB1538713A/en not_active Expired
- 1977-02-14 SE SE7701624A patent/SE423234B/xx not_active IP Right Cessation
- 1977-02-16 ZA ZA770918A patent/ZA77918B/xx unknown
- 1977-02-17 IL IL51481A patent/IL51481A/xx unknown
- 1977-02-18 CA CA272,080A patent/CA1068269A/en not_active Expired
- 1977-02-18 AU AU22443/77A patent/AU506937B2/en not_active Expired
- 1977-02-23 YU YU499/77A patent/YU41294B/xx unknown
- 1977-02-24 IE IE399/77A patent/IE44522B1/en not_active IP Right Cessation
- 1977-02-24 PT PT66227A patent/PT66227B/pt unknown
- 1977-02-25 DE DE2708192A patent/DE2708192C3/de not_active Expired
- 1977-02-28 SU SU772457100A patent/SU644387A3/ru active
- 1977-02-28 BE BE1007976A patent/BE851878A/xx not_active IP Right Cessation
- 1977-02-28 JP JP52021433A patent/JPS604188B2/ja not_active Expired
- 1977-02-28 FI FI770634A patent/FI62082C/fi not_active IP Right Cessation
- 1977-02-28 FR FR7705819A patent/FR2372828A1/fr active Granted
- 1977-02-28 DK DK86877A patent/DK145858C/da not_active IP Right Cessation
- 1977-02-28 NZ NZ183450A patent/NZ183450A/xx unknown
- 1977-02-28 NO NO770674A patent/NO146499C/no unknown
- 1977-02-28 HU HU76UO128A patent/HU173641B/hu unknown
- 1977-02-28 ES ES545368A patent/ES8707447A1/es not_active Expired
- 1977-02-28 NL NLAANVRAGE7702123,A patent/NL169591C/xx not_active IP Right Cessation
- 1977-03-01 PL PL1977196354A patent/PL105559B1/pl not_active IP Right Cessation
- 1977-03-01 RO RO7789566A patent/RO73095A/ro unknown
- 1977-03-01 DD DD7700197618A patent/DD129652A5/xx unknown
- 1977-03-01 CH CH255577A patent/CH618436A5/fr not_active IP Right Cessation
- 1977-03-01 CS CS771358A patent/CS191332B2/cs unknown
- 1977-03-01 BG BG035558A patent/BG29724A3/xx unknown
- 1977-03-01 AR AR266724A patent/AR210937A1/es active
- 1977-03-01 LU LU76868A patent/LU76868A1/xx unknown
-
1981
- 1981-07-02 HK HK308/81A patent/HK30881A/xx unknown
- 1981-12-30 MY MY271/81A patent/MY8100271A/xx unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PL201586A1 (pl) | Sposob wytwarzania nowych zwiazkow spiro-hydantionowych | |
PL196505A1 (pl) | Sposob wytwarzania nowych zwiazkow aminoalkiloheterocyklicznych | |
PL195088A1 (pl) | Sposob wytwarzania n-fosfonometyloglicyny | |
PL201286A1 (pl) | Sposob wytwarzania nowych 1-aryloksy-2-hydroksy-3-alkileno-aminopropanow | |
PL196354A1 (pl) | Sposob wytwarzania nowych,krystalicznych postaci chlorowodorku prazozyny | |
PL200630A1 (pl) | Sposob wytwarzania nowych fenyloetyloamin | |
PL200289A1 (pl) | Sposob wytwarzania zwiazkow 3-chlorocefemowych | |
PL196820A1 (pl) | Sposob wytwarzania zwiazkow 3-chlorowcometylocefemowych-3 | |
PL205632A1 (pl) | Sposob wytwarzania 1-azolilo-3,3-dwumetylo-1-feno-ksybutanonow-2 | |
PL200534A1 (pl) | Sposob wytwarzania nowych oksadeztiacefalosporyn | |
PL200583A1 (pl) | Sposob wytwarzania nowych pochodnych benzopiranu | |
PL200605A1 (pl) | Sposob wytwarzania nowych pochodnych metioninoenkefaliny | |
PL198731A1 (pl) | Sposob wytwarzania nowych pochodnych 1-hydroksy-3-alkilodwubenzo/b,d/piranu | |
PL104866B1 (pl) | Sposob wytwarzania nowych pirydobenzodwuazepinonow | |
PL202660A1 (pl) | Sposob wytwarzania nowych pochodnych spirooksazolidynodionu | |
PL203359A1 (pl) | Sposob wytwarzania nowych zasadowo podstawionych o-propylooksymow | |
PL196269A1 (pl) | Sposob wytwarzania nowych zwiazkow iminowych | |
PL201161A1 (pl) | Sposob wytwarzania nowych pochodnych 9-chloroprednisolonu | |
PL203537A1 (pl) | Sposob wytwarzania n,n-dwupodstawionych chlorowcoacyloamidow | |
PL196061A1 (pl) | Sposob wytwarzania nowych pochodnych indolizyny | |
PL199361A1 (pl) | Sposob wytwarzania 6a,10a-cis-szesciowodorodwubenzopiranonow | |
PL202935A1 (pl) | Sposob wytwarzania estrow | |
PL201883A1 (pl) | Sposob wytwarzania nowych pochodnych trans-5a-arylo-dziesieciowodorobenzazepiny | |
PL197311A1 (pl) | Sposob wytwarzania nowych zwiazkow ketotia | |
PL203486A1 (pl) | Sposob wytwarzania nowych pochodnych 6,7-dwumetoksy-1,2,3,4-czterowodoro-1-izochinolino-acetamidu |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
LAPS | Decisions on the lapse of the protection rights |
Effective date: 20020820 |