ES545368A0 - Un procedimiento para la preparacion de la forma alfa cris- talina de clorhidrato de 2-(4-(2-furoil)piperazin-1-il)-4-a-mino-6,7-dimetoxiquinazolina. - Google Patents

Un procedimiento para la preparacion de la forma alfa cris- talina de clorhidrato de 2-(4-(2-furoil)piperazin-1-il)-4-a-mino-6,7-dimetoxiquinazolina.

Info

Publication number: ES545368A0
Authority: ES; Spain
Prior art keywords: dimetoxiquinazoline; furoil; mino; piperazin; procedure
Prior art date: 1976-03-01
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES545368A

Other languages

English (en)

Other versions

ES8707447A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Corp Belgium

Pfizer Corp SRL

Original Assignee

Pfizer Corp Belgium

Pfizer Corp SRL

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-03-01

Filing date

1977-02-28

Publication date

1978-06-01

1977-02-28 Application filed by Pfizer Corp Belgium, Pfizer Corp SRL filed Critical Pfizer Corp Belgium

1978-06-01 Publication of ES545368A0 publication Critical patent/ES545368A0/es

1987-08-16 Publication of ES8707447A1 publication Critical patent/ES8707447A1/es

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Saccharide Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

ES545368A 1976-03-01 1977-02-28 Un procedimiento para la preparacion de la forma alfa cris- talina de clorhidrato de 2-(4-(2-furoil)piperazin-1-il)-4-a-mino-6,7-dimetoxiquinazolina. Expired ES8707447A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/662,937 US4092315A (en)	1976-03-01	1976-03-01	Novel crystalline forms of prazosin hydrochloride

Publications (2)

Publication Number	Publication Date
ES545368A0 true ES545368A0 (es)	1978-06-01
ES8707447A1 ES8707447A1 (es)	1987-08-16

Family

ID=24659839

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES545368A Expired ES8707447A1 (es)	1976-03-01	1977-02-28	Un procedimiento para la preparacion de la forma alfa cris- talina de clorhidrato de 2-(4-(2-furoil)piperazin-1-il)-4-a-mino-6,7-dimetoxiquinazolina.

Country Status (32)

Country	Link
US (1)	US4092315A (es)
JP (1)	JPS604188B2 (es)
AR (1)	AR210937A1 (es)
AU (1)	AU506937B2 (es)
BE (1)	BE851878A (es)
BG (1)	BG29724A3 (es)
CA (1)	CA1068269A (es)
CH (1)	CH618436A5 (es)
CS (1)	CS191332B2 (es)
DD (1)	DD129652A5 (es)
DE (1)	DE2708192C3 (es)
DK (1)	DK145858C (es)
ES (1)	ES8707447A1 (es)
FI (1)	FI62082C (es)
FR (1)	FR2372828A1 (es)
GB (1)	GB1538713A (es)
HK (1)	HK30881A (es)
HU (1)	HU173641B (es)
IE (1)	IE44522B1 (es)
IL (1)	IL51481A (es)
LU (1)	LU76868A1 (es)
MY (1)	MY8100271A (es)
NL (1)	NL169591C (es)
NO (1)	NO146499C (es)
NZ (1)	NZ183450A (es)
PL (1)	PL105559B1 (es)
PT (1)	PT66227B (es)
RO (1)	RO73095A (es)
SE (1)	SE423234B (es)
SU (1)	SU644387A3 (es)
YU (1)	YU41294B (es)
ZA (1)	ZA77918B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MX5483E (es) *	1977-08-04	1983-08-23	Abbott Lab	Procedimiento para la preparacion del dihidrato clorhidrato de 1-(4-amino-6,7-dimetoxi-2-quinazolinil)-4-(2-tetrahidrofuroil)piperazina
GB1591490A (en) *	1977-08-04	1981-06-24	Abbott Lab	1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride dihydrate
US4197301A (en) *	1978-10-16	1980-04-08	Allergan Pharmaceuticals, Inc.	Topical ophthalmic use of Prazosin
FI67699C (fi) *	1979-01-31	1985-05-10	Orion Yhtymae Oy	Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolinhydroklorid med blodtryckssaenkande verkan
US4440769A (en) *	1983-02-11	1984-04-03	Abbott Laboratories	2-(4-Phenylalkanoylpiperazin-1-yl) quinazoline compounds, pharmaceutical compositions and method of producing α1 antagonistic activity
FI79107C (fi) *	1984-06-25	1989-11-10	Orion Yhtymae Oy	Foerfarande foer framstaellning av stabil -form av prazosinhydroklorid.
US5322943A (en) *	1985-09-12	1994-06-21	The Upjohn Company	Piperazine compounds which are substituted
US4601897A (en) *	1985-11-06	1986-07-22	Pfizer Inc.	Prazosin-pirbuterol combination for bronchodilation
DE3683760D1 (de) *	1986-03-21	1992-03-12	Heumann Pharma Gmbh & Co	Kristalline, wasserfreie sigma -form von 2-(4-(2-furoyl-(2-piperazin)-1-yl)-4-amino-6,7-dimethoxychinazolinhydrochlorid und verfahren zu ihrer herstellung.
US5110927A (en) *	1987-12-31	1992-05-05	The United States Of America As Represented By The Department Of Health And Human Services	Prazosin analog with increased selectivity and duration of action
JP2652272B2 (ja) *	1990-12-31	1997-09-10	住化ファインケム株式会社	１−（４−アミノ−６，７−ジメトキシ−２−キナゾリニル）−４−（２−テトラヒドロフロイル）ピペラジン塩酸塩の新規な結晶体および該結晶体の製造方法
GB9417310D0 (en) *	1994-08-27	1994-10-19	Pfizer Ltd	Therapeutic agents
US5952003A (en) *	1996-08-01	1999-09-14	Novartis Corporation	Terazosin capsules
EP0849264A1 (de) *	1996-12-20	1998-06-24	HEUMANN PHARMA GmbH	Neue polymorphe Form von doxazosinmesylat (Form I)
EP0849266B8 (de) *	1996-12-20	2007-10-03	Heumann PCS GmbH	Neue polymorphe Form von Doxazosinmesylat (Form III)
EP0849265A1 (de) *	1996-12-20	1998-06-24	HEUMANN PHARMA GmbH	Neue polymorphe Form von Doxazosin-Mesylat (Form II)
EP3172377B1 (en)	2014-07-21	2018-09-12	KEIR Manufacturing, Inc.	Aerodynamic flyer bow

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3663706A (en) *	1969-09-29	1972-05-16	Pfizer	Use of 2,4-diaminoquinazolines as hypotensive agents

1976
- 1976-03-01 US US05/662,937 patent/US4092315A/en not_active Expired - Lifetime
1977
- 1977-02-11 GB GB5756/77A patent/GB1538713A/en not_active Expired
- 1977-02-14 SE SE7701624A patent/SE423234B/xx not_active IP Right Cessation
- 1977-02-16 ZA ZA770918A patent/ZA77918B/xx unknown
- 1977-02-17 IL IL51481A patent/IL51481A/xx unknown
- 1977-02-18 CA CA272,080A patent/CA1068269A/en not_active Expired
- 1977-02-18 AU AU22443/77A patent/AU506937B2/en not_active Expired
- 1977-02-23 YU YU499/77A patent/YU41294B/xx unknown
- 1977-02-24 IE IE399/77A patent/IE44522B1/en not_active IP Right Cessation
- 1977-02-24 PT PT66227A patent/PT66227B/pt unknown
- 1977-02-25 DE DE2708192A patent/DE2708192C3/de not_active Expired
- 1977-02-28 SU SU772457100A patent/SU644387A3/ru active
- 1977-02-28 BE BE1007976A patent/BE851878A/xx not_active IP Right Cessation
- 1977-02-28 JP JP52021433A patent/JPS604188B2/ja not_active Expired
- 1977-02-28 FI FI770634A patent/FI62082C/fi not_active IP Right Cessation
- 1977-02-28 FR FR7705819A patent/FR2372828A1/fr active Granted
- 1977-02-28 DK DK86877A patent/DK145858C/da not_active IP Right Cessation
- 1977-02-28 NZ NZ183450A patent/NZ183450A/xx unknown
- 1977-02-28 NO NO770674A patent/NO146499C/no unknown
- 1977-02-28 HU HU76UO128A patent/HU173641B/hu unknown
- 1977-02-28 ES ES545368A patent/ES8707447A1/es not_active Expired
- 1977-02-28 NL NLAANVRAGE7702123,A patent/NL169591C/xx not_active IP Right Cessation
- 1977-03-01 PL PL1977196354A patent/PL105559B1/pl not_active IP Right Cessation
- 1977-03-01 RO RO7789566A patent/RO73095A/ro unknown
- 1977-03-01 DD DD7700197618A patent/DD129652A5/xx unknown
- 1977-03-01 CH CH255577A patent/CH618436A5/fr not_active IP Right Cessation
- 1977-03-01 CS CS771358A patent/CS191332B2/cs unknown
- 1977-03-01 BG BG035558A patent/BG29724A3/xx unknown
- 1977-03-01 AR AR266724A patent/AR210937A1/es active
- 1977-03-01 LU LU76868A patent/LU76868A1/xx unknown
1981
- 1981-07-02 HK HK308/81A patent/HK30881A/xx unknown
- 1981-12-30 MY MY271/81A patent/MY8100271A/xx unknown

Also Published As

Publication number	Publication date
HU173641B (en)	1979-07-28
CH618436A5 (es)	1980-07-31
BE851878A (fr)	1977-08-29
IL51481A0 (en)	1977-04-29
DE2708192B2 (de)	1979-08-02
FI62082B (fi)	1982-07-30
NL169591B (nl)	1982-03-01
FI770634A (es)	1977-09-02
YU41294B (en)	1987-02-28
DE2708192A1 (de)	1977-09-08
FR2372828A1 (fr)	1978-06-30
DK145858C (da)	1983-09-12
NZ183450A (en)	1979-03-16
CS191332B2 (en)	1979-06-29
JPS604188B2 (ja)	1985-02-01
NO770674L (no)	1977-09-02
CA1068269A (en)	1979-12-18
PL196354A1 (pl)	1978-02-27
FI62082C (fi)	1982-11-10
ES8707447A1 (es)	1987-08-16
SE7701624L (sv)	1977-09-02
DK145858B (da)	1983-03-21
PL105559B1 (pl)	1979-10-31
SU644387A3 (ru)	1979-01-25
NO146499C (no)	1982-10-13
GB1538713A (en)	1979-01-24
NL169591C (nl)	1982-08-02
DK86877A (da)	1977-09-02
HK30881A (en)	1981-07-10
PT66227B (en)	1978-07-14
FR2372828B1 (es)	1980-02-01
ZA77918B (en)	1977-12-28
DE2708192C3 (de)	1980-05-08
DD129652A5 (de)	1978-02-01
JPS52105206A (en)	1977-09-03
BG29724A3 (en)	1981-01-15
AU2244377A (en)	1978-11-23
NL7702123A (nl)	1977-09-05
RO73095A (ro)	1981-06-26
LU76868A1 (es)	1977-09-21
US4092315A (en)	1978-05-30
IE44522B1 (en)	1981-12-30
AR210937A1 (es)	1977-09-30
MY8100271A (en)	1981-12-31
PT66227A (en)	1977-03-01
YU49977A (en)	1983-12-31
IL51481A (en)	1980-09-16
IE44522L (en)	1977-09-01
SE423234B (sv)	1982-04-26
NO146499B (no)	1982-07-05
AU506937B2 (en)	1980-01-31

Publication	Publication Date	Title
ES545368A0 (es)	1978-06-01	Un procedimiento para la preparacion de la forma alfa cris- talina de clorhidrato de 2-(4-(2-furoil)piperazin-1-il)-4-a-mino-6,7-dimetoxiquinazolina.
ES491534A0 (es)	1981-04-01	Un procedimiento para la preparacion de nuevos bis-esteres de metanodiol.
AR224008A1 (es)	1981-10-15	Procedimiento para preparar polihidro-3,7-dimetil-8-(2-(tetrahidro-4-hidroxi-6-oxo-2h-piran-2-il)-etil)-1-naftil-2-metilbutirato
ES226784Y (es)	1977-08-16	Un dispositivo para el acoplamiento de elementos desmonta- bles.
NL7711788A (nl)	1978-05-08	Nieuwe gibberellinezouten.
ES498020A0 (es)	1982-06-01	Un procedimiento para al preparacion de un ce)-5-(halogenovinil)-arabino-furano-siluracilo.
ES496661A0 (es)	1982-03-01	Procedimiento para la fabricacion de un tejido, en especial de una cinta tejida.
AR211080A1 (es)	1977-10-14	Procedimiento mejorado para fabricar embutidus.
ES506281A0 (es)	1982-12-01	Un procedimiento para la preparacion de 4-(4-imidazolil)piridinas 2-sustituidas.
AR213659A1 (es)	1979-02-28	Procedimiento para la preparacion de 2-(4-(aroil o heteroaroil)-piperazin-1-il)-4-amino-6,7-dimetoxiquinazolinas
IT1084503B (it)	1985-05-25	Procedimento per la preparazione di una poliolefina.
DK140578A (da)	1978-10-01	Fremgangsmaade til fremstilling af 2-(2!,2!,-trihalogenethyl)-4-halogencyclobutan-1-oner.
AR208612A1 (es)	1977-02-15	Un procedimiento para la fabricacion de escobas cepillos o implementos similares
ES510236A0 (es)	1983-04-16	Procedimiento para preparar compuestos azoicos.
ES488797A0 (es)	1981-02-16	Un procedimiento para la preparacion de cloruro de 2-(p-hi- droxi-fenil)glicilo.
AR214527A1 (es)	1979-06-29	Procedimiento para la preparacion de-n-6-cloronicotionoil-d,1 homocisteina tiolactona
AR211410Q (es)	1977-12-15	Procedimiento para preparar 2-(2,2- diciclohexietil)piperidina
FI830278L (fi)	1983-01-26	Som mellanprodukter anvaendbara 2-(2-aminotiazol-4-yl)-2-oxiiminoaettiksyrederivat
ES220957Y (es)	1977-03-01	Calzo para mobiliario.
ES218652Y (es)	1977-03-01	Utensilio para la colocacion de junquillos.
ES219543Y (es)	1977-02-01	Protector para calzado femenino.
ES219312Y (es)	1977-03-01	Partesoles para fachadas.
AR209605A1 (es)	1977-05-13	Un procedimiento para la obtencion de la 2-(3,4,5-trimetoxibencil)3,4-dimetilpiridina
AR204361A1 (es)	1975-12-22	Procedimiento para la preparacion de un 2-(2',6'-dihalofenil)-amino-2-imidazolina y sus sales
ES225114Y (es)	1977-06-16	Pieza ceramica para fachadas.

Legal Events

Date	Code	Title	Description
1997-11-01	FD1A	Patent lapsed	Effective date: 19971001