DD129652A5 - Verfahren zur herstellung der kristallinen alpha-form von 2-eckige klammer auf 4-(2-furoyl)-piperazin-1-yl eckige klammer zu-4-amino-6,7-dimethoxy-chinazolin-hydrochlorid - Google Patents

Verfahren zur herstellung der kristallinen alpha-form von 2-eckige klammer auf 4-(2-furoyl)-piperazin-1-yl eckige klammer zu-4-amino-6,7-dimethoxy-chinazolin-hydrochlorid

Info

Publication number: DD129652A5
Authority: DD; German Democratic Republic
Prior art keywords: chinazoline; clamber; furoyl; dimethoxy; piperazine
Prior art date: 1976-03-01

Application number

DD7700197618A

Other languages

German (de)

English (en)

Inventor

Ernest J Bianco

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-03-01

Filing date

1977-03-01

Publication date

1978-02-01

1977-03-01 Application filed by Pfizer filed Critical Pfizer

1978-02-01 Publication of DD129652A5 publication Critical patent/DD129652A5/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Saccharide Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

DD7700197618A 1976-03-01 1977-03-01 Verfahren zur herstellung der kristallinen alpha-form von 2-eckige klammer auf 4-(2-furoyl)-piperazin-1-yl eckige klammer zu-4-amino-6,7-dimethoxy-chinazolin-hydrochlorid DD129652A5 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/662,937 US4092315A (en)	1976-03-01	1976-03-01	Novel crystalline forms of prazosin hydrochloride

Publications (1)

Publication Number	Publication Date
DD129652A5 true DD129652A5 (de)	1978-02-01

Family

ID=24659839

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DD7700197618A DD129652A5 (de)	1976-03-01	1977-03-01	Verfahren zur herstellung der kristallinen alpha-form von 2-eckige klammer auf 4-(2-furoyl)-piperazin-1-yl eckige klammer zu-4-amino-6,7-dimethoxy-chinazolin-hydrochlorid

Country Status (32)

Country	Link
US (1)	US4092315A (xx)
JP (1)	JPS604188B2 (xx)
AR (1)	AR210937A1 (xx)
AU (1)	AU506937B2 (xx)
BE (1)	BE851878A (xx)
BG (1)	BG29724A3 (xx)
CA (1)	CA1068269A (xx)
CH (1)	CH618436A5 (xx)
CS (1)	CS191332B2 (xx)
DD (1)	DD129652A5 (xx)
DE (1)	DE2708192C3 (xx)
DK (1)	DK145858C (xx)
ES (1)	ES8707447A1 (xx)
FI (1)	FI62082C (xx)
FR (1)	FR2372828A1 (xx)
GB (1)	GB1538713A (xx)
HK (1)	HK30881A (xx)
HU (1)	HU173641B (xx)
IE (1)	IE44522B1 (xx)
IL (1)	IL51481A (xx)
LU (1)	LU76868A1 (xx)
MY (1)	MY8100271A (xx)
NL (1)	NL169591C (xx)
NO (1)	NO146499C (xx)
NZ (1)	NZ183450A (xx)
PL (1)	PL105559B1 (xx)
PT (1)	PT66227B (xx)
RO (1)	RO73095A (xx)
SE (1)	SE423234B (xx)
SU (1)	SU644387A3 (xx)
YU (1)	YU41294B (xx)
ZA (1)	ZA77918B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MX5483E (es) *	1977-08-04	1983-08-23	Abbott Lab	Procedimiento para la preparacion del dihidrato clorhidrato de 1-(4-amino-6,7-dimetoxi-2-quinazolinil)-4-(2-tetrahidrofuroil)piperazina
GB1591490A (en) *	1977-08-04	1981-06-24	Abbott Lab	1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride dihydrate
US4197301A (en) *	1978-10-16	1980-04-08	Allergan Pharmaceuticals, Inc.	Topical ophthalmic use of Prazosin
FI67699C (fi) *	1979-01-31	1985-05-10	Orion Yhtymae Oy	Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolinhydroklorid med blodtryckssaenkande verkan
US4440769A (en) *	1983-02-11	1984-04-03	Abbott Laboratories	2-(4-Phenylalkanoylpiperazin-1-yl) quinazoline compounds, pharmaceutical compositions and method of producing α1 antagonistic activity
FI79107C (fi) *	1984-06-25	1989-11-10	Orion Yhtymae Oy	Foerfarande foer framstaellning av stabil -form av prazosinhydroklorid.
US5322943A (en) *	1985-09-12	1994-06-21	The Upjohn Company	Piperazine compounds which are substituted
US4601897A (en) *	1985-11-06	1986-07-22	Pfizer Inc.	Prazosin-pirbuterol combination for bronchodilation
DE3683760D1 (de) *	1986-03-21	1992-03-12	Heumann Pharma Gmbh & Co	Kristalline, wasserfreie sigma -form von 2-(4-(2-furoyl-(2-piperazin)-1-yl)-4-amino-6,7-dimethoxychinazolinhydrochlorid und verfahren zu ihrer herstellung.
US5110927A (en) *	1987-12-31	1992-05-05	The United States Of America As Represented By The Department Of Health And Human Services	Prazosin analog with increased selectivity and duration of action
JP2652272B2 (ja) *	1990-12-31	1997-09-10	住化ファインケム株式会社	１−（４−アミノ−６，７−ジメトキシ−２−キナゾリニル）−４−（２−テトラヒドロフロイル）ピペラジン塩酸塩の新規な結晶体および該結晶体の製造方法
GB9417310D0 (en) *	1994-08-27	1994-10-19	Pfizer Ltd	Therapeutic agents
US5952003A (en) *	1996-08-01	1999-09-14	Novartis Corporation	Terazosin capsules
EP0849264A1 (de) *	1996-12-20	1998-06-24	HEUMANN PHARMA GmbH	Neue polymorphe Form von doxazosinmesylat (Form I)
EP0849266B8 (de) *	1996-12-20	2007-10-03	Heumann PCS GmbH	Neue polymorphe Form von Doxazosinmesylat (Form III)
EP0849265A1 (de) *	1996-12-20	1998-06-24	HEUMANN PHARMA GmbH	Neue polymorphe Form von Doxazosin-Mesylat (Form II)
EP3172377B1 (en)	2014-07-21	2018-09-12	KEIR Manufacturing, Inc.	Aerodynamic flyer bow

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3663706A (en) *	1969-09-29	1972-05-16	Pfizer	Use of 2,4-diaminoquinazolines as hypotensive agents

1976
- 1976-03-01 US US05/662,937 patent/US4092315A/en not_active Expired - Lifetime
1977
- 1977-02-11 GB GB5756/77A patent/GB1538713A/en not_active Expired
- 1977-02-14 SE SE7701624A patent/SE423234B/xx not_active IP Right Cessation
- 1977-02-16 ZA ZA770918A patent/ZA77918B/xx unknown
- 1977-02-17 IL IL51481A patent/IL51481A/xx unknown
- 1977-02-18 CA CA272,080A patent/CA1068269A/en not_active Expired
- 1977-02-18 AU AU22443/77A patent/AU506937B2/en not_active Expired
- 1977-02-23 YU YU499/77A patent/YU41294B/xx unknown
- 1977-02-24 IE IE399/77A patent/IE44522B1/en not_active IP Right Cessation
- 1977-02-24 PT PT66227A patent/PT66227B/pt unknown
- 1977-02-25 DE DE2708192A patent/DE2708192C3/de not_active Expired
- 1977-02-28 SU SU772457100A patent/SU644387A3/ru active
- 1977-02-28 BE BE1007976A patent/BE851878A/xx not_active IP Right Cessation
- 1977-02-28 JP JP52021433A patent/JPS604188B2/ja not_active Expired
- 1977-02-28 FI FI770634A patent/FI62082C/fi not_active IP Right Cessation
- 1977-02-28 FR FR7705819A patent/FR2372828A1/fr active Granted
- 1977-02-28 DK DK86877A patent/DK145858C/da not_active IP Right Cessation
- 1977-02-28 NZ NZ183450A patent/NZ183450A/xx unknown
- 1977-02-28 NO NO770674A patent/NO146499C/no unknown
- 1977-02-28 HU HU76UO128A patent/HU173641B/hu unknown
- 1977-02-28 ES ES545368A patent/ES8707447A1/es not_active Expired
- 1977-02-28 NL NLAANVRAGE7702123,A patent/NL169591C/xx not_active IP Right Cessation
- 1977-03-01 PL PL1977196354A patent/PL105559B1/pl not_active IP Right Cessation
- 1977-03-01 RO RO7789566A patent/RO73095A/ro unknown
- 1977-03-01 DD DD7700197618A patent/DD129652A5/xx unknown
- 1977-03-01 CH CH255577A patent/CH618436A5/fr not_active IP Right Cessation
- 1977-03-01 CS CS771358A patent/CS191332B2/cs unknown
- 1977-03-01 BG BG035558A patent/BG29724A3/xx unknown
- 1977-03-01 AR AR266724A patent/AR210937A1/es active
- 1977-03-01 LU LU76868A patent/LU76868A1/xx unknown
1981
- 1981-07-02 HK HK308/81A patent/HK30881A/xx unknown
- 1981-12-30 MY MY271/81A patent/MY8100271A/xx unknown

Also Published As

Publication number	Publication date
HU173641B (en)	1979-07-28
CH618436A5 (xx)	1980-07-31
BE851878A (fr)	1977-08-29
IL51481A0 (en)	1977-04-29
DE2708192B2 (de)	1979-08-02
FI62082B (fi)	1982-07-30
NL169591B (nl)	1982-03-01
FI770634A (xx)	1977-09-02
YU41294B (en)	1987-02-28
DE2708192A1 (de)	1977-09-08
FR2372828A1 (fr)	1978-06-30
DK145858C (da)	1983-09-12
NZ183450A (en)	1979-03-16
CS191332B2 (en)	1979-06-29
JPS604188B2 (ja)	1985-02-01
NO770674L (no)	1977-09-02
CA1068269A (en)	1979-12-18
PL196354A1 (pl)	1978-02-27
FI62082C (fi)	1982-11-10
ES8707447A1 (es)	1987-08-16
SE7701624L (sv)	1977-09-02
DK145858B (da)	1983-03-21
PL105559B1 (pl)	1979-10-31
SU644387A3 (ru)	1979-01-25
NO146499C (no)	1982-10-13
GB1538713A (en)	1979-01-24
NL169591C (nl)	1982-08-02
DK86877A (da)	1977-09-02
HK30881A (en)	1981-07-10
PT66227B (en)	1978-07-14
FR2372828B1 (xx)	1980-02-01
ZA77918B (en)	1977-12-28
ES545368A0 (es)	1978-06-01
DE2708192C3 (de)	1980-05-08
JPS52105206A (en)	1977-09-03
BG29724A3 (en)	1981-01-15
AU2244377A (en)	1978-11-23
NL7702123A (nl)	1977-09-05
RO73095A (ro)	1981-06-26
LU76868A1 (xx)	1977-09-21
US4092315A (en)	1978-05-30
IE44522B1 (en)	1981-12-30
AR210937A1 (es)	1977-09-30
MY8100271A (en)	1981-12-31
PT66227A (en)	1977-03-01
YU49977A (en)	1983-12-31
IL51481A (en)	1980-09-16
IE44522L (en)	1977-09-01
SE423234B (sv)	1982-04-26
NO146499B (no)	1982-07-05
AU506937B2 (en)	1980-01-31

Publication	Publication Date	Title
DD129652A5 (de)	1978-02-01	Verfahren zur herstellung der kristallinen alpha-form von 2-eckige klammer auf 4-(2-furoyl)-piperazin-1-yl eckige klammer zu-4-amino-6,7-dimethoxy-chinazolin-hydrochlorid
DD129006A5 (de)	1977-12-21	Verfahren zur herstellung von pyrimidinderivaten
DD138313A5 (de)	1979-10-24	Verfahren zur herstellung von alkenderivaten
DD134526A5 (de)	1979-03-07	Verfahren zur herstellung von alkyloxinderivaten der 7-aminothiazolylazetamidozephalosporansaeure
DD134519A5 (de)	1979-03-07	Verfahren zur herstellung von n'-eckige klammer auf 4-(phenethyloxy)-phenyl eckige klammer zu-n-methyl-n-methoxyharnstoffen
DD137225A5 (de)	1979-08-22	Verfahren zur herstellung von 1,2,4-triazin-5-on-derivaten
AT345266B (de)	1978-09-11	Verfahren zur herstellung von neuen substituierten n-alkyl-2,4-dinitro-6-trifluormethyldiphenylaminen
AT353796B (de)	1979-12-10	Verfahren zur herstellung von 3,4-dihydro-2- (1h)-chinazolinonen und 3,4-dihydro-2(1h)- chinazolinthionen
DD135905A5 (de)	1979-06-06	Verfahren zur herstellung von harnstoffderivaten
LU79591A1 (de)	1979-06-13	Verfahren zur herstellung von benzimidazol-derivaten
AT358007B (de)	1980-08-11	Verfahren zur herstellung von neuen n-(4-iso- hexylcyclohexylcarbonyl)-aminosaeurederivaten
DD135488A5 (de)	1979-05-09	Verfahren zur herstellung von pyridazinon-derivaten
DD132492A5 (de)	1978-10-04	Verfahren zur herstellung von n-(1-allyl-2'-pyrrolidylmethyl)-2,3-dimethoxy-5-sulfamoylbenzamid und seinen derivaten
AT353276B (de)	1979-11-12	Verfahren zur herstellung von 3,4-dihydro-2(1h) -chinazolinon-derivaten
DD137926A5 (de)	1979-10-03	Verfahren zur herstellung von n-substituierten alpha-ketocarbonsaeureamiden
DD137353A5 (de)	1979-08-29	Verfahren zur herstellung von uracilderivaten
LU79290A1 (de)	1979-05-25	Verfahren zur herstellung von chinazolin-derivaten
DD129790A5 (de)	1978-02-08	Verfahren zur herstellung von phenylpiperazinderivaten
DD131927A5 (de)	1978-08-09	Verfahren zur herstellung cancerostatisch und immunstimulierend wirkender 1-(n-acyl-carbamoyl)-2-cyanaziridine
ATA313780A (de)	1982-11-15	Verfahren zur herstellung von 4-(substituierten) thio-1-b-d-ribofuranosylpyrazolo(3,4-d)pyrimidinderivaten
DD137228A5 (de)	1979-08-22	Verfahren zur herstellung von 4-(1-hydroxy-1-methylaethyl)-3-cyclohexen-1-on-ketalen
DD134522A5 (de)	1979-03-07	Verfahren zur herstellung von 1,2,4-triazin-5-on-derivaten
ATA486078A (de)	1979-09-15	Verfahren zur herstellung von 1-(4-isopropyl- mercaptophenyl)-2-n-octylaminopropanol
AT366664B (de)	1982-04-26	Verfahren zur herstellung von neuen n-(3-arylthioureido)-phthalimiden
DD133671A1 (de)	1979-01-17	Verfahren zur herstellung von 6,7-dimethoxy-4-amino-2-eckige klammer auf 4-(2-furoyl)-1-piperazinyl eckige klammer zu chinazolin