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PE20200175A1 - Formas de dosificacion de ruxolitinib de liberacion sostenida - Google Patents

Formas de dosificacion de ruxolitinib de liberacion sostenida

Info

Publication number
PE20200175A1
PE20200175A1 PE2019001988A PE2019001988A PE20200175A1 PE 20200175 A1 PE20200175 A1 PE 20200175A1 PE 2019001988 A PE2019001988 A PE 2019001988A PE 2019001988 A PE2019001988 A PE 2019001988A PE 20200175 A1 PE20200175 A1 PE 20200175A1
Authority
PE
Peru
Prior art keywords
ruxolitinib
sustained release
dosage forms
dosage form
hydroxypropylmethylcellulose
Prior art date
Application number
PE2019001988A
Other languages
English (en)
Inventor
Yong Ni
Krishnaswamy Yeleswaram
Susan Erickson-Viitanen
William V Williams
Bhavnish Parikh
Original Assignee
Incyte Holdings Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49681181&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20200175(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Incyte Holdings Corp filed Critical Incyte Holdings Corp
Publication of PE20200175A1 publication Critical patent/PE20200175A1/es

Links

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    • A—HUMAN NECESSITIES
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    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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  • Epidemiology (AREA)
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  • Neurosurgery (AREA)
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  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)

Abstract

Referida a una forma de dosificacion de liberacion sostenida que comprende al menos un ingrediente activo que es ruxolitinib o una sal farmaceuticamente activa del mismo y de 10% a 30% en peso de hidroxipropilmetilcelulosa, en donde el ruxolitinib esta presente en dicha forma de dosificacion en una cantidad de entre 10 a 60 mg en forma de base libre. Dicha forma de dosificacion es util en el tratamiento de enfermedades relacionadas con la quinasa Janus tales como trastornos hiperproliferativos
PE2019001988A 2012-11-15 2013-11-14 Formas de dosificacion de ruxolitinib de liberacion sostenida PE20200175A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261726893P 2012-11-15 2012-11-15
US201361769408P 2013-02-26 2013-02-26
PCT/US2013/070012 WO2014078486A1 (en) 2012-11-15 2013-11-14 Sustained-release dosage forms of ruxolitinib

Publications (1)

Publication Number Publication Date
PE20200175A1 true PE20200175A1 (es) 2020-01-24

Family

ID=49681181

Family Applications (2)

Application Number Title Priority Date Filing Date
PE2015000624A PE20151157A1 (es) 2012-11-15 2013-11-14 Formas de dosificacion de ruxolitinib de liberacion sostenida
PE2019001988A PE20200175A1 (es) 2012-11-15 2013-11-14 Formas de dosificacion de ruxolitinib de liberacion sostenida

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PE2015000624A PE20151157A1 (es) 2012-11-15 2013-11-14 Formas de dosificacion de ruxolitinib de liberacion sostenida

Country Status (35)

Country Link
US (8) US10166191B2 (es)
EP (2) EP3949953A1 (es)
JP (4) JP2015537030A (es)
KR (3) KR20220162825A (es)
CN (3) CN113384546A (es)
AR (1) AR093490A1 (es)
AU (4) AU2013344780B2 (es)
BR (1) BR112015010663B1 (es)
CA (2) CA2890755C (es)
CL (1) CL2015001286A1 (es)
CR (2) CR20190073A (es)
CY (1) CY1124446T1 (es)
DK (1) DK2919766T3 (es)
EA (1) EA201590930A1 (es)
ES (1) ES2880814T3 (es)
HK (1) HK1213796A1 (es)
HR (1) HRP20211158T1 (es)
HU (1) HUE055894T2 (es)
IL (4) IL291391B (es)
LT (1) LT2919766T (es)
MX (3) MX2020012676A (es)
MY (1) MY191357A (es)
NZ (2) NZ708157A (es)
PE (2) PE20151157A1 (es)
PH (2) PH12020551186B1 (es)
PL (1) PL2919766T3 (es)
PT (1) PT2919766T (es)
RS (1) RS62329B1 (es)
SG (3) SG10201703685UA (es)
SI (1) SI2919766T1 (es)
SM (1) SMT202100436T1 (es)
TW (4) TWI761825B (es)
UA (1) UA120834C2 (es)
WO (1) WO2014078486A1 (es)
ZA (1) ZA202202711B (es)

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PH12013501001A1 (en) 2010-11-19 2019-09-02 Incyte Holdings Corp Cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as jak inhibitors
TWI577676B (zh) 2011-06-20 2017-04-11 英塞特控股公司 作為ｊａｋ抑制劑之吖丁啶基苯基、吡啶基或吡基羧醯胺衍生物
UA111854C2 (uk) 2011-09-07 2016-06-24 Інсайт Холдінгс Корпорейшн Способи і проміжні сполуки для отримання інгібіторів jak
PL3450434T3 (pl) * 2012-06-15 2021-10-04 Concert Pharmaceuticals, Inc. Deuterowane pochodne ruksolitynibu
TWI646099B (zh) 2012-11-01 2019-01-01 英塞特控股公司 作爲ｊａｋ抑制劑之三環稠合噻吩衍生物
HUE055894T2 (hu) * 2012-11-15 2021-12-28 Incyte Holdings Corp A ruxolitinib nyújtott felszabadulású dózisformái
RS62867B1 (sr) 2013-03-06 2022-02-28 Incyte Holdings Corp Postupci i intermedijeri za dobijanje inhibitora jak
ES2626793T3 (es) 2013-05-17 2017-07-26 Incyte Holdings Corporation Derivados de bipirazole como inhibidores de JAK
CR20190343A (es) 2013-08-07 2019-10-02 Incyte Corp FORMAS DE DOSIFICACIÓN DE LIBERACIÓN PROLONGADA PARA UN INHIBIDOR DE JAK 1 (Divisional de Exp: 2016-0102)
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