HK1030753A1 - Fracture healing using pthrp analogs. - Google Patents

Fracture healing using pthrp analogs.

Info

Publication number: HK1030753A1
Authority: HK; Hong Kong
Prior art keywords: fracture healing; pthrp analogs; pthrp; analogs; healing
Prior art date: 1997-09-09

Application number

HK01101739A

Other languages

English (en)

Inventor

Brian Henry Vickery

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-09-09

Filing date

2001-03-12

Publication date

2001-05-18

2001-03-12 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2001-05-18 Publication of HK1030753A1 publication Critical patent/HK1030753A1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Endocrinology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Physical Education & Sports Medicine (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Orthopedic Medicine & Surgery (AREA)
Epidemiology (AREA)
Rheumatology (AREA)
Immunology (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Toxicology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

HK01101739A 1997-09-09 2001-03-12 Fracture healing using pthrp analogs. HK1030753A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US5832497P	1997-09-09	1997-09-09
PCT/EP1998/005550 WO1999012561A2 (en)	1997-09-09	1998-09-02	FRACTURE HEALING USING PTHrP ANALOGS

Publications (1)

Publication Number	Publication Date
HK1030753A1 true HK1030753A1 (en)	2001-05-18

Family

ID=22016113

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK01101739A HK1030753A1 (en)	1997-09-09	2001-03-12	Fracture healing using pthrp analogs.

Country Status (32)

Country	Link
US (1)	US6583114B2 (zh)
EP (1)	EP1005359B1 (zh)
JP (1)	JP2002509854A (zh)
KR (1)	KR100679778B1 (zh)
CN (1)	CN1210059C (zh)
AR (1)	AR015435A1 (zh)
AT (1)	ATE297754T1 (zh)
AU (1)	AU752925B2 (zh)
BR (1)	BR9812068A (zh)
CA (1)	CA2302255C (zh)
CO (1)	CO4890856A1 (zh)
CZ (1)	CZ298701B6 (zh)
DE (1)	DE69830591T2 (zh)
ES (1)	ES2244090T3 (zh)
HK (1)	HK1030753A1 (zh)
HR (1)	HRP20000109A2 (zh)
HU (1)	HU226866B1 (zh)
IL (2)	IL134719A0 (zh)
MA (1)	MA26545A1 (zh)
MY (1)	MY121291A (zh)
NO (1)	NO323740B1 (zh)
NZ (1)	NZ502970A (zh)
PE (1)	PE117399A1 (zh)
PL (1)	PL195703B1 (zh)
RS (1)	RS49707B (zh)
RU (1)	RU2224539C2 (zh)
SA (1)	SA98190565B1 (zh)
TR (1)	TR200000649T2 (zh)
TW (1)	TW552139B (zh)
UY (1)	UY25172A1 (zh)
WO (1)	WO1999012561A2 (zh)
ZA (1)	ZA988030B (zh)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1295605A3 (en) *	1998-08-19	2003-10-29	Eli Lilly And Company	Method of increasing bone toughness and stiffness and reducing fractures
US20040033950A1 (en)	2000-09-26	2004-02-19	Hock Janet M.	Method of increasing bone toughness and stiffness and reducing fractures
AR033639A1 (es) *	1998-08-19	2004-01-07	Lilly Co Eli	Uso de hormonas paratiroideas para preparar medicamentos para reducir el riesgo de fracturas oseas vertebrales o no vertebrales en seres humanos con riesgo de padecer o que padecen osteoporosis
EP1769804B1 (en) *	1998-08-19	2012-09-19	Eli Lilly And Company	hPTH(1-34) for use in preventing or reducing the incidence or severity of vertebral and / or non vertebral fracture in a male human
CA2245903A1 (en) *	1998-09-28	2000-03-28	Mcgill University	Use of pex in the treatment of metabolic bone diseases
JP4834224B2 (ja)	1999-03-05	2011-12-14	デュークユニバーシティ	Ｃ１６不飽和ｆｐ−選択的プロスタグランジン類縁体
US20020037914A1 (en)	2000-03-31	2002-03-28	Delong Mitchell Anthony	Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020013294A1 (en)	2000-03-31	2002-01-31	Delong Mitchell Anthony	Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US20020172693A1 (en)	2000-03-31	2002-11-21	Delong Michell Anthony	Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US6560487B1 (en)	2000-05-08	2003-05-06	International Rehabilitative Sciences, Inc.	Electro-medical device for use with biologics
US6393328B1 (en) *	2000-05-08	2002-05-21	International Rehabilitative Sciences, Inc.	Multi-functional portable electro-medical device
US6675048B2 (en) *	2000-05-08	2004-01-06	International Rehabilitative Sciences, Inc.	Electro-medical device for use with biologics
AU2003207512B2 (en)	2002-01-10	2008-06-12	Osteotrophin Llc	Treatment of bone disorders with skeletal anabolic drugs
US7399826B1 (en)	2003-10-02	2008-07-15	Ali Sadat M	Peptide for promoting healing of fractures
CN101056647A (zh) *	2004-10-08	2007-10-17	福布斯梅迪泰克（研究）公司	肠血管活性多肽药物
AU2006315132A1 (en) *	2005-11-10	2007-05-24	Board Of Control Of Michigan Technological University	Black bear parathyroid hormone and methods of using black bear parathyroid hormone
WO2007133580A2 (en) *	2006-05-09	2007-11-22	Zelos Therapeutics, Inc.	Use of pth (1-31) and optionally g-csf for hematopoietic stimulation
USRE49444E1 (en)	2006-10-03	2023-03-07	Radius Health, Inc.	Method of treating osteoporosis comprising administration of PTHrP analog
US7803770B2 (en)	2006-10-03	2010-09-28	Radius Health, Inc.	Method of treating osteoporosis comprising administration of PTHrP analog
CN102274492B (zh)	2006-10-03	2014-11-26	半径健康公司	骨合成代谢蛋白质的药物递送方法
EP1961765A1 (en) *	2006-12-08	2008-08-27	Zealand Pharma A/S	Truncated PTH peptides with a cyclic conformation
JP5564167B2 (ja) *	2008-05-22	2014-07-30	日本たばこ産業株式会社	苦味マスキング剤及び苦味低減方法
US8870876B2 (en)	2009-02-13	2014-10-28	Tarsus Medical Inc.	Methods and devices for treating hallux valgus
US8563513B2 (en)	2009-03-27	2013-10-22	Van Andel Research Institute	Parathyroid hormone peptides and parathyroid hormone-related protein peptides and methods of use
US8277459B2 (en)	2009-09-25	2012-10-02	Tarsus Medical Inc.	Methods and devices for treating a structural bone and joint deformity
EP2509996A1 (en)	2009-12-07	2012-10-17	Michigan Technological University	Black bear parathyroid hormone and methods of using black bear parathyroid hormone
US8652141B2 (en)	2010-01-21	2014-02-18	Tarsus Medical Inc.	Methods and devices for treating hallux valgus
US8696719B2 (en)	2010-06-03	2014-04-15	Tarsus Medical Inc.	Methods and devices for treating hallux valgus
CN104146961B (zh) *	2014-07-04	2018-02-27	深圳职业技术学院	一种薄膜蒸发法制备载细胞因子和骨蛋白微球的方法
SG11201708858WA (en)	2015-04-29	2017-11-29	Radius Pharmaceuticals Inc	Methods of treating cancer
CN108025042A (zh) *	2015-07-06	2018-05-11	董正欣	PTHrP类似物的新型制剂
AU2017253674B2 (en)	2016-04-18	2021-07-29	Kindeva Drug Delivery L.P.	Formulations of abaloparatide, transdermal patches thereof, and uses thereof
JP7481115B2 (ja)	2017-01-05	2024-05-10	ラジウスファーマシューティカルズ，インコーポレイテッド	Ｒａｄ１９０１－２ｈｃｌの多形性形態
US10996208B2 (en)	2017-04-28	2021-05-04	Radius Health, Inc.	Abaloparatide formulations and methods of testing, storing, modifying, and using same
AU2019297421B2 (en)	2018-07-04	2024-08-29	Radius Pharmaceuticals, Inc.	Polymorphic forms of RAD 1901-2HCL
EP4027899A4 (en) *	2019-09-12	2023-08-16	Radius Health, Inc.	METHODS OF ENHANCING SPINE FUSION USING ABALOPARATIDE
CN112646042A (zh) *	2019-10-10	2021-04-13	陕西麦科奥特科技有限公司	活性多肽化合物
AU2022205801A1 (en) *	2021-01-05	2023-07-13	Radius Health, Inc.	Treatment of long bone fractures with abaloparatide

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3935738A1 (de) *	1989-10-27	1991-05-08	Forssmann Wolf Georg	Arzneimittel, enthaltend das humane parathormon-fragment (1-37) als aktiven wirkstoff
US5821225A (en) *	1992-07-14	1998-10-13	Syntex (U.S.A.) Inc.	Method for the treatment of corticosteroid induced osteopenia comprising administration of modified PTH or PTHrp
US5589452A (en)	1992-07-14	1996-12-31	Syntex (U.S.A.) Inc.	Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis
US5977070A (en) *	1992-07-14	1999-11-02	Piazza; Christin Teresa	Pharmaceutical compositions for the nasal delivery of compounds useful for the treatment of osteoporosis
AU672790B2 (en) *	1992-07-15	1996-10-17	Novartis Ag	Variants of parathyroid hormone and its fragments
CN1070500C (zh) *	1993-07-13	2001-09-05	森德克斯(美国)股份有限公司	甲状旁腺激素类似物和甲状旁腺激素相关肽：合成和治疗骨质疏松症的用途
TW273513B (zh) *	1993-10-27	1996-04-01	Chugai Pharmaceutical Co Ltd
JPH08310965A (ja) *	1995-05-16	1996-11-26	Chugai Pharmaceut Co Ltd	骨癒合促進剤
US5717062A (en) *	1995-06-07	1998-02-10	Beth Israel Hospital Association	Cyclic analogs of PTH and PTHrP
US5723577A (en) *	1995-07-13	1998-03-03	Biomeasure Inc.	Analogs of parathyroid hormone
US5955574A (en) *	1995-07-13	1999-09-21	Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.	Analogs of parathyroid hormone

1998
- 1998-09-02 JP JP2000510458A patent/JP2002509854A/ja active Pending
- 1998-09-02 IL IL13471998A patent/IL134719A0/xx unknown
- 1998-09-02 ES ES98951341T patent/ES2244090T3/es not_active Expired - Lifetime
- 1998-09-02 ZA ZA988030A patent/ZA988030B/xx unknown
- 1998-09-02 CN CNB988089696A patent/CN1210059C/zh not_active Expired - Lifetime
- 1998-09-02 RS YUP-127/00A patent/RS49707B/sr unknown
- 1998-09-02 CZ CZ20000862A patent/CZ298701B6/cs not_active IP Right Cessation
- 1998-09-02 WO PCT/EP1998/005550 patent/WO1999012561A2/en active IP Right Grant
- 1998-09-02 PL PL98339449A patent/PL195703B1/pl unknown
- 1998-09-02 AU AU97406/98A patent/AU752925B2/en not_active Expired
- 1998-09-02 HU HU0004560A patent/HU226866B1/hu unknown
- 1998-09-02 BR BR9812068-9A patent/BR9812068A/pt not_active IP Right Cessation
- 1998-09-02 DE DE69830591T patent/DE69830591T2/de not_active Expired - Lifetime
- 1998-09-02 CA CA2302255A patent/CA2302255C/en not_active Expired - Lifetime
- 1998-09-02 TR TR2000/00649T patent/TR200000649T2/xx unknown
- 1998-09-02 AT AT98951341T patent/ATE297754T1/de active
- 1998-09-02 RU RU2000109305/15A patent/RU2224539C2/ru active
- 1998-09-02 EP EP98951341A patent/EP1005359B1/en not_active Expired - Lifetime
- 1998-09-02 KR KR1020007002454A patent/KR100679778B1/ko not_active IP Right Cessation
- 1998-09-02 NZ NZ502970A patent/NZ502970A/en not_active IP Right Cessation
- 1998-09-03 US US09/146,802 patent/US6583114B2/en not_active Expired - Lifetime
- 1998-09-07 PE PE1998000838A patent/PE117399A1/es not_active Application Discontinuation
- 1998-09-07 CO CO98051174A patent/CO4890856A1/es unknown
- 1998-09-07 MY MYPI98004075A patent/MY121291A/en unknown
- 1998-09-07 UY UY25172A patent/UY25172A1/es not_active Application Discontinuation
- 1998-09-07 AR ARP980104456A patent/AR015435A1/es unknown
- 1998-09-07 TW TW087114825A patent/TW552139B/zh not_active IP Right Cessation
- 1998-09-08 MA MA25247A patent/MA26545A1/fr unknown
- 1998-09-21 SA SA98190565A patent/SA98190565B1/ar unknown
2000
- 2000-02-24 IL IL134719A patent/IL134719A/en not_active IP Right Cessation
- 2000-02-29 HR HR20000109A patent/HRP20000109A2/hr not_active Application Discontinuation
- 2000-03-08 NO NO20001195A patent/NO323740B1/no not_active IP Right Cessation
2001
- 2001-03-12 HK HK01101739A patent/HK1030753A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
US20020077281A1 (en)	2002-06-20
NO20001195L (no)	2000-03-08
PL339449A1 (en)	2000-12-18
KR100679778B1 (ko)	2007-02-07
HU226866B1 (en)	2009-12-28
UY25172A1 (es)	2001-01-31
AU752925B2 (en)	2002-10-03
EP1005359A2 (en)	2000-06-07
CN1269726A (zh)	2000-10-11
NO323740B1 (no)	2007-07-02
IL134719A (en)	2010-04-29
NO20001195D0 (no)	2000-03-08
DE69830591D1 (de)	2005-07-21
ES2244090T3 (es)	2005-12-01
MA26545A1 (fr)	2004-12-20
ZA988030B (en)	1999-03-09
CA2302255C (en)	2011-11-08
CZ2000862A3 (cs)	2000-09-13
SA98190565B1 (ar)	2006-07-30
PE117399A1 (es)	1999-11-20
WO1999012561A3 (en)	1999-05-14
ATE297754T1 (de)	2005-07-15
NZ502970A (en)	2002-03-01
CZ298701B6 (cs)	2007-12-27
TW552139B (en)	2003-09-11
IL134719A0 (en)	2001-04-30
HUP0004560A2 (hu)	2001-04-28
EP1005359B1 (en)	2005-06-15
AR015435A1 (es)	2001-05-02
HUP0004560A3 (en)	2005-11-28
WO1999012561A9 (en)	2000-03-16
AU9740698A (en)	1999-03-29
KR20010023795A (ko)	2001-03-26
CN1210059C (zh)	2005-07-13
JP2002509854A (ja)	2002-04-02
HRP20000109A2 (en)	2001-02-28
TR200000649T2 (tr)	2000-09-21
PL195703B1 (pl)	2007-10-31
MY121291A (en)	2006-01-28
RU2224539C2 (ru)	2004-02-27
YU12700A (sh)	2004-09-03
DE69830591T2 (de)	2006-05-04
RS49707B (sr)	2007-12-31
WO1999012561A2 (en)	1999-03-18
CA2302255A1 (en)	1999-03-18
CO4890856A1 (es)	2000-02-28
BR9812068A (pt)	2000-09-26
US6583114B2 (en)	2003-06-24

Publication	Publication Date	Title
HK1030753A1 (en)	2001-05-18	Fracture healing using pthrp analogs.
ZA982253B (en)	1999-09-17	Therapeutic compositions.
ZA99454B (en)	2000-10-23	Novel dosage form.
ZA987844B (en)	2000-02-28	Therapeutic combinations.
HK1025746A1 (en)	2000-11-24	Syringe.
ZA9811849B (en)	2000-06-23	Vaccine.
ZA984969B (en)	1999-12-09	Vaccine.
ZA988789B (en)	2000-03-29	Vaccine.
ZA987839B (en)	2000-02-28	Combination therapy.
ZA987843B (en)	2000-02-28	Combination therapy.
HK1027957A1 (en)	2001-02-02	Pharmaceutical composition.
ZA981029B (en)	1999-08-10	Pharmaceutical agents.
ZA9811504B (en)	2000-06-15	Novel pharmaceutical.
AU8495998A (en)	1999-04-27	Improved dosage units
ZA9811506B (en)	2000-11-06	Novel pharmaceutical.
ZA989680B (en)	1999-07-23	Pharmaceutical composition.
ZA9811715B (en)	1999-09-20	Aqueous insecticidal pour-on treatment.
ZA9811505B (en)	2000-11-06	Novel pharmaceutical.
ZA973209B (en)	1997-11-20	Therapeutic compounds.
ZA987392B (en)	2000-02-17	Pharmaceutical composition.
PL338781A1 (en)	2000-11-20	Dosage form
ZA200304047B (en)	2004-04-28	Analogues of GLP-1.
GB2323042B (en)	1999-04-07	Nebulisers
GB9827865D0 (en)	1999-02-10	Medicament
ZA982558B (en)	1999-09-27	Novel Pharmaceutical.

Legal Events

Date	Code	Title	Description
2018-09-21	PE	Patent expired	Effective date: 20180901