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AR033639A1 - Uso de hormonas paratiroideas para preparar medicamentos para reducir el riesgo de fracturas oseas vertebrales o no vertebrales en seres humanos con riesgo de padecer o que padecen osteoporosis - Google Patents

Uso de hormonas paratiroideas para preparar medicamentos para reducir el riesgo de fracturas oseas vertebrales o no vertebrales en seres humanos con riesgo de padecer o que padecen osteoporosis

Info

Publication number
AR033639A1
AR033639A1 ARP990104133A ARP990104133A AR033639A1 AR 033639 A1 AR033639 A1 AR 033639A1 AR P990104133 A ARP990104133 A AR P990104133A AR P990104133 A ARP990104133 A AR P990104133A AR 033639 A1 AR033639 A1 AR 033639A1
Authority
AR
Argentina
Prior art keywords
risk
vertebral
suffering
osteoporosis
reduce
Prior art date
Application number
ARP990104133A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26792729&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR033639(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of AR033639A1 publication Critical patent/AR033639A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Uso de una hormona paratiroidea caracterizado porque comprende la preparación de medicamentos para reducir el riesgo de fracturas óseas vertebrales o no vertebrales en seres humanos con riesgo de padecer o que padecen osteoporosis, sin administración concurrente de agentes de resorción ósea diferentes de la vitamina D o calcio, dichos medicamentos formulados en dosis para la administración diaria de 20 a 40 microg de dicha hormona.
ARP990104133A 1998-08-19 1999-08-18 Uso de hormonas paratiroideas para preparar medicamentos para reducir el riesgo de fracturas oseas vertebrales o no vertebrales en seres humanos con riesgo de padecer o que padecen osteoporosis AR033639A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9715198P 1998-08-19 1998-08-19
US9974698P 1998-09-10 1998-09-10

Publications (1)

Publication Number Publication Date
AR033639A1 true AR033639A1 (es) 2004-01-07

Family

ID=26792729

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990104133A AR033639A1 (es) 1998-08-19 1999-08-18 Uso de hormonas paratiroideas para preparar medicamentos para reducir el riesgo de fracturas oseas vertebrales o no vertebrales en seres humanos con riesgo de padecer o que padecen osteoporosis

Country Status (33)

Country Link
US (2) US6977077B1 (es)
EP (3) EP2266598B1 (es)
JP (5) JP2002523375A (es)
KR (1) KR100454207B1 (es)
CN (1) CN1205997C (es)
AR (1) AR033639A1 (es)
AT (1) ATE231000T1 (es)
AU (1) AU746277B2 (es)
BR (1) BR9909445A (es)
CA (1) CA2325371C (es)
CO (1) CO5130020A1 (es)
CY (2) CY1113343T1 (es)
CZ (1) CZ301017B6 (es)
DE (2) DE15152726T1 (es)
DK (4) DK2266598T3 (es)
DZ (1) DZ2873A1 (es)
EA (1) EA003362B1 (es)
ES (4) ES2549551T3 (es)
HK (3) HK1030545A1 (es)
HR (1) HRP20000755A2 (es)
HU (2) HU1200430D0 (es)
ID (1) ID29039A (es)
IL (2) IL138829A0 (es)
MY (1) MY129227A (es)
NO (2) NO323984B1 (es)
NZ (1) NZ507056A (es)
PE (1) PE20001089A1 (es)
PL (1) PL201688B1 (es)
PT (4) PT2266598T (es)
TR (1) TR200003455T2 (es)
TW (1) TW576747B (es)
UA (1) UA72205C2 (es)
WO (1) WO2000010596A1 (es)

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US6770623B1 (en) * 1997-12-09 2004-08-03 Eli Lilly And Company Stabilized teriparatide solutions
AR033639A1 (es) 1998-08-19 2004-01-07 Lilly Co Eli Uso de hormonas paratiroideas para preparar medicamentos para reducir el riesgo de fracturas oseas vertebrales o no vertebrales en seres humanos con riesgo de padecer o que padecen osteoporosis
US20040033950A1 (en) 2000-09-26 2004-02-19 Hock Janet M. Method of increasing bone toughness and stiffness and reducing fractures
WO2001022093A1 (en) * 1999-09-20 2001-03-29 Eli Lilly And Company Method for monitoring treatment with a parathyroid hormone
US7247609B2 (en) 2001-12-18 2007-07-24 Universitat Zurich Growth factor modified protein matrices for tissue engineering
AU2003207512B2 (en) * 2002-01-10 2008-06-12 Osteotrophin Llc Treatment of bone disorders with skeletal anabolic drugs
US8088734B2 (en) 2003-01-21 2012-01-03 Unigene Laboratories Inc. Oral delivery of peptides
CA2539357A1 (en) * 2003-09-19 2005-03-31 Pfizer Products Inc. Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and parathyroid hormone
US7244709B2 (en) * 2004-05-10 2007-07-17 Nastech Pharamecutical Company Inc. Compositions and methods for enhanced mucosal delivery of parathyroid hormone
US20060127320A1 (en) * 2004-05-10 2006-06-15 Nastech Pharmaceutical Company Inc. Method of delivering parathyroid hormone to a human
US20060189533A1 (en) * 2004-05-10 2006-08-24 Nastech Pharmaceutical Company Inc. Stable pharmaceutical dosage forms of teriparatide
US20060052305A1 (en) * 2004-05-10 2006-03-09 Nastech Pharmaceutical Company Inc. Method of treating osteoporosis using intranasal parathyroid hormone
BRPI0509788A (pt) 2004-05-13 2007-10-23 Alza Corp aparato e método para liberação transdérmica de agentes de hormÈnio paratireóides
US7648965B2 (en) 2004-05-14 2010-01-19 Unigene Laboratories Inc. Method for fostering bone formation and preservation
US20060069021A1 (en) * 2004-08-13 2006-03-30 Nastech Pharmaceutical Company Inc. Compositions and methods for intranasal administration of inactive analogs of PTH or inactivated preparations of PTH or PTH analogs
US8575101B2 (en) 2005-01-06 2013-11-05 Kuros Biosurgery Ag Supplemented matrices for the repair of bone fractures
WO2006073711A2 (en) * 2005-01-06 2006-07-13 Kuros Biosurgery Ag Use of a matrix comprising a contrast agent in soft tissues
JP2008540522A (ja) * 2005-05-11 2008-11-20 ユニジーン・ラボラトリーズ・インコーポレーテッド 骨の形成および保存を促進するための方法
US20070173447A1 (en) * 2005-10-25 2007-07-26 Nastech Pharmaceutical Company Inc. Method for treating osteoporosis by intranasal delivery of teriparatide with an anti-resorptive agent
AU2006315132A1 (en) * 2005-11-10 2007-05-24 Board Of Control Of Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
US20080051332A1 (en) * 2005-11-18 2008-02-28 Nastech Pharmaceutical Company Inc. Method of modulating hematopoietic stem cells and treating hematologic diseases using intranasal parathyroid hormone
US20080119408A1 (en) * 2006-07-07 2008-05-22 Nastech Pharmaceutical Company Inc. Pth formulations for intranasal delivery
EP1961765A1 (en) * 2006-12-08 2008-08-27 Zealand Pharma A/S Truncated PTH peptides with a cyclic conformation
BRPI0810530B8 (pt) 2007-04-13 2021-06-22 Kuros Biosurgery Ag composição, uso da mesma, biomaterial sintético, seu método de fabricação e kit para formar o mesmo
US20110137243A1 (en) * 2007-09-06 2011-06-09 Abbott Cardiovascular Systems Inc. Coating On A Balloon Device
US9457056B2 (en) * 2007-12-04 2016-10-04 Ben-Gurion University Of The Negev Research And Development Authority Peptides comprising alternating hydrophobic and anionic amino acids for treatment of osteoporosis
JP2012512812A (ja) 2007-12-28 2012-06-07 クロス・バイオサージェリー・アクチェンゲゼルシャフト フィブリンフォームに組込まれたｐｄｇｆ融合タンパク質
IN2012DN00857A (es) * 2009-09-09 2015-07-10 Asahi Kasei Pharma Corp
EP2509996A1 (en) 2009-12-07 2012-10-17 Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
US9295663B2 (en) 2010-07-14 2016-03-29 Abbott Cardiovascular Systems Inc. Drug coated balloon with in-situ formed drug containing microspheres
WO2012111852A1 (ja) * 2011-02-17 2012-08-23 帝人ファーマ株式会社 椎体骨折治療剤及びその評価方法
WO2012123028A1 (en) 2011-03-16 2012-09-20 Kuros Biosurgery Ag Pharmaceutical formulation for use in spinal fusion
CN108195965B (zh) 2011-06-07 2021-02-23 旭化成制药株式会社 含pth肽冷冻干燥制剂的检査方法及包含该含pth肽冷冻干燥制剂的医药品的制造方法
US9700485B2 (en) 2013-04-24 2017-07-11 Corning Incorporated Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
JP6815407B2 (ja) 2016-02-01 2021-01-20 イーライ リリー アンド カンパニー 副甲状腺ホルモン−抗ｒａｎｋｌ抗体融合化合物
EP3576774A4 (en) * 2017-02-01 2020-10-07 The Johns Hopkins University PARATHYROID HORMONE AND REGENERATION OF DEGENERATIVE DISCS
JP6577683B2 (ja) * 2017-09-22 2019-09-18 旭化成ファーマ株式会社 安定性に優れるテリパラチド含有液状医薬組成物
CN119258199A (zh) 2018-10-29 2025-01-07 旭化成制药株式会社 特立帕肽或其盐在骨质疏松症治疗和/或预防剂的制备中的应用
WO2021030222A1 (en) 2019-08-09 2021-02-18 Flagship Pioneering Innovations Vi, Llc Modulators of parathyroid hormone receptor (pthr1)
GB2590692A (en) * 2019-12-24 2021-07-07 Corthotec Ltd Composition for improved bone fracture healing

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US4086196A (en) 1975-03-28 1978-04-25 Armour Pharmaceutical Company Parathyroid hormone
IL78342A (en) * 1985-04-04 1991-06-10 Gen Hospital Corp Pharmaceutical composition for treatment of osteoporosis in humans comprising a parathyroid hormone or a fragment thereof
DE3935738A1 (de) 1989-10-27 1991-05-08 Forssmann Wolf Georg Arzneimittel, enthaltend das humane parathormon-fragment (1-37) als aktiven wirkstoff
US5208041A (en) 1991-05-23 1993-05-04 Allelix Biopharmaceuticals Inc. Essentially pure human parathyroid hormone
CA2126299C (en) 1994-06-20 2000-12-12 Gordon E. Willick Parathyroid hormone analogues for the treatment of osteoporosis
JPH0873376A (ja) * 1994-09-07 1996-03-19 Asahi Chem Ind Co Ltd 骨粗鬆症治療薬
US5747456A (en) * 1994-12-19 1998-05-05 Beth Israel Deaconess Medical Center Continuous low-dose administration of parathyroid hormone or its agonist
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CA2206657C (en) * 1994-12-22 2009-05-19 Astra Aktiebolag Therapeutic preparation for inhalation containing parathyroid hormone, pth
JPH08310965A (ja) 1995-05-16 1996-11-26 Chugai Pharmaceut Co Ltd 骨癒合促進剤
JP2002509854A (ja) * 1997-09-09 2002-04-02 エフ．ホフマン−ラ ロシュ アーゲー ＰＴＨｒＰ類似体を使用する骨折治癒
MY120063A (en) 1997-12-09 2005-08-30 Lilly Co Eli Stabilized teriparatide solutions
US20040033950A1 (en) * 2000-09-26 2004-02-19 Hock Janet M. Method of increasing bone toughness and stiffness and reducing fractures
AR033639A1 (es) * 1998-08-19 2004-01-07 Lilly Co Eli Uso de hormonas paratiroideas para preparar medicamentos para reducir el riesgo de fracturas oseas vertebrales o no vertebrales en seres humanos con riesgo de padecer o que padecen osteoporosis
US6907597B1 (en) 2000-10-13 2005-06-14 Ati International Srl Method and apparatus for constructing an executable program in memory
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JP5796714B2 (ja) 2012-01-13 2015-10-21 株式会社リコー 定着装置及び画像形成装置
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Also Published As

Publication number Publication date
KR100454207B1 (ko) 2004-10-26
HK1212602A1 (zh) 2016-06-17
DE15152726T1 (de) 2015-12-10
NO20072983L (no) 2000-11-24
CZ20004134A3 (cs) 2001-08-15
CA2325371C (en) 2004-08-17
HK1030545A1 (en) 2001-05-11
PE20001089A1 (es) 2000-11-04
KR20010072763A (ko) 2001-07-31
EP1059933B1 (en) 2003-01-15
AU746277B2 (en) 2002-04-18
CO5130020A1 (es) 2002-02-27
PT2266598T (pt) 2017-05-02
EA200001015A1 (ru) 2001-02-26
EA003362B1 (ru) 2003-04-24
BR9909445A (pt) 2000-12-12
DK2907522T1 (da) 2015-10-19
WO2000010596A1 (en) 2000-03-02
HUP0101594A3 (en) 2002-01-28
TR200003455T2 (tr) 2001-06-21
ES2549551T3 (es) 2017-11-27
DK1059933T3 (da) 2003-04-07
IL138829A0 (en) 2001-10-31
HUP0101594A2 (hu) 2001-11-28
NZ507056A (en) 2003-10-31
ID29039A (id) 2001-07-26
HU1200430D0 (hu) 2001-11-28
PL201688B1 (pl) 2009-04-30
US20050197294A1 (en) 2005-09-08
EP1059933A1 (en) 2000-12-20
MY129227A (en) 2007-03-30
DK1769804T3 (da) 2012-10-15
JP2014139220A (ja) 2014-07-31
PT2907522T (pt) 2017-10-23
NO20005947D0 (no) 2000-11-24
UA72205C2 (uk) 2005-02-15
CY1113343T1 (el) 2016-06-22
EP2266598A1 (en) 2010-12-29
US6977077B1 (en) 2005-12-20
ES2393200T3 (es) 2012-12-19
PT1059933E (pt) 2003-06-30
AU5575099A (en) 2000-03-14
JP2015028065A (ja) 2015-02-12
NO323984B1 (no) 2007-07-30
CN1205997C (zh) 2005-06-15
DE69904918T2 (de) 2003-11-13
PL343595A1 (en) 2001-08-27
NO20005947L (no) 2000-11-24
DE69904918D1 (de) 2003-02-20
ES2549551T1 (es) 2015-10-29
CA2325371A1 (en) 2000-03-02
HK1102496A1 (en) 2007-11-23
CN1308545A (zh) 2001-08-15
JP2017190332A (ja) 2017-10-19
JP2011021035A (ja) 2011-02-03
DK2266598T3 (en) 2017-05-15
ES2621653T3 (es) 2017-07-04
DK2907522T3 (en) 2017-10-23
EP2266598B1 (en) 2017-02-22
JP6177718B2 (ja) 2017-08-09
EP2907522A1 (en) 2015-08-19
TW576747B (en) 2004-02-21
ES2190244T3 (es) 2003-07-16
HRP20000755A2 (en) 2001-02-28
US7163684B2 (en) 2007-01-16
PT1769804E (pt) 2012-11-13
ATE231000T1 (de) 2003-02-15
HU230697B1 (hu) 2017-09-28
CZ301017B6 (cs) 2009-10-14
JP2002523375A (ja) 2002-07-30
DZ2873A1 (fr) 2003-12-15
CY1119552T1 (el) 2018-03-07
EP2907522B1 (en) 2017-08-02
IL138829A (en) 2011-01-31

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