FI925661A0 - Injicerbar farmaceutisk komposition - Google Patents
Injicerbar farmaceutisk kompositionInfo
- Publication number
- FI925661A0 FI925661A0 FI925661A FI925661A FI925661A0 FI 925661 A0 FI925661 A0 FI 925661A0 FI 925661 A FI925661 A FI 925661A FI 925661 A FI925661 A FI 925661A FI 925661 A0 FI925661 A0 FI 925661A0
- Authority
- FI
- Finland
- Prior art keywords
- microspheres
- formulations
- contain
- dia
- microns
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000004005 microsphere Substances 0.000 abstract 8
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 abstract 4
- 238000009472 formulation Methods 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 4
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 abstract 2
- 239000003433 contraceptive agent Substances 0.000 abstract 2
- 230000002254 contraceptive effect Effects 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 abstract 2
- 239000011261 inert gas Substances 0.000 abstract 2
- 229960003387 progesterone Drugs 0.000 abstract 2
- 239000000186 progesterone Substances 0.000 abstract 2
- CMWTZPSULFXXJA-UHFFFAOYSA-N Naproxen Natural products C1=C(C(C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-UHFFFAOYSA-N 0.000 abstract 1
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 229960005309 estradiol Drugs 0.000 abstract 1
- 229960000905 indomethacin Drugs 0.000 abstract 1
- 239000000155 melt Substances 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
- 230000008018 melting Effects 0.000 abstract 1
- 229960002009 naproxen Drugs 0.000 abstract 1
- CMWTZPSULFXXJA-VIFPVBQESA-N naproxen Chemical compound C1=C([C@H](C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-VIFPVBQESA-N 0.000 abstract 1
- 239000003921 oil Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000007921 spray Substances 0.000 abstract 1
- 238000005507 spraying Methods 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Nutrition Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9007416A FR2663223B1 (fr) | 1990-06-14 | 1990-06-14 | Forme galenique parenterale. |
FR9007416 | 1990-06-14 | ||
PCT/EP1991/001096 WO1991019484A1 (fr) | 1990-06-14 | 1991-06-12 | Composition pharmaceutique injectable |
EP9101096 | 1991-06-12 |
Publications (3)
Publication Number | Publication Date |
---|---|
FI925661L FI925661L (fi) | 1992-12-11 |
FI925661A0 true FI925661A0 (fi) | 1992-12-11 |
FI107698B FI107698B (fi) | 2001-09-28 |
Family
ID=9397598
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI925661A FI107698B (fi) | 1990-06-14 | 1992-12-11 | Kiinteitä, ei-huokoisia mikropallosia |
Country Status (30)
Country | Link |
---|---|
US (3) | US5360616A (fi) |
EP (1) | EP0533739B1 (fi) |
JP (1) | JP2675675B2 (fi) |
KR (1) | KR0157439B1 (fi) |
CN (1) | CN1057442C (fi) |
AT (1) | ATE109658T1 (fi) |
AU (1) | AU661275B2 (fi) |
BG (1) | BG61179B1 (fi) |
BR (1) | BR9106545A (fi) |
CA (1) | CA2085344C (fi) |
CZ (1) | CZ286793B6 (fi) |
DE (1) | DE69103419T2 (fi) |
DK (1) | DK0533739T3 (fi) |
ES (1) | ES2059142T3 (fi) |
FI (1) | FI107698B (fi) |
FR (1) | FR2663223B1 (fi) |
HU (1) | HUT68709A (fi) |
IE (1) | IE62679B1 (fi) |
IL (1) | IL98459A (fi) |
NO (1) | NO302998B1 (fi) |
NZ (1) | NZ238542A (fi) |
PL (1) | PL167234B1 (fi) |
PT (1) | PT97975B (fi) |
RU (1) | RU2104692C1 (fi) |
SK (1) | SK280564B6 (fi) |
TN (1) | TNSN91048A1 (fi) |
UA (1) | UA27043C2 (fi) |
UY (1) | UY23240A1 (fi) |
WO (1) | WO1991019484A1 (fi) |
ZA (1) | ZA914550B (fi) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2663224B1 (fr) * | 1990-06-14 | 1995-01-20 | Applicationes Farmaceuticas Sa | Forme galenique parenterale. |
NZ260408A (en) | 1993-05-10 | 1996-05-28 | Euro Celtique Sa | Controlled release preparation comprising tramadol |
GB9313642D0 (en) * | 1993-07-01 | 1993-08-18 | Glaxo Group Ltd | Method and apparatus for the formation of particles |
US5965161A (en) | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
FR2732621B1 (fr) * | 1995-04-10 | 1997-06-06 | Rhone Poulenc Chimie | Perles d'un produit presentant le phenomene de surfusion et leur procede d'obtention |
US5904935A (en) * | 1995-06-07 | 1999-05-18 | Alza Corporation | Peptide/protein suspending formulations |
US6028057A (en) * | 1998-02-19 | 2000-02-22 | Thorn Bioscience, Llc | Regulation of estrus and ovulation in gilts |
ATE265846T1 (de) * | 1998-02-25 | 2004-05-15 | Abbott Lab | Butorphanol enthaltende formulierungen mit verzögerter freisetzung |
US6287693B1 (en) | 1998-02-25 | 2001-09-11 | John Claude Savoir | Stable shaped particles of crystalline organic compounds |
JP2003526629A (ja) * | 1999-08-20 | 2003-09-09 | ノートン ヘルスケアー リミテッド | 経肺または経鼻投与のための粉末の製造法 |
US20070254008A1 (en) * | 2001-07-13 | 2007-11-01 | Flow Focusing, Inc. | Antibiotic formulation and method of treatment |
US20030055075A1 (en) * | 2001-07-13 | 2003-03-20 | Rubsamen Reid M. | Programmable controlled release injectable opioid formulation |
US20070254009A1 (en) * | 2001-07-13 | 2007-11-01 | Flow Focusing, Inc. | Antibiotic/bone morphogenic protein formulation and method of treatment |
GB0117696D0 (en) * | 2001-07-20 | 2001-09-12 | Bradford Particle Design Plc | Particle information |
AU2004246870B2 (en) * | 2003-06-13 | 2009-07-23 | Skendi Finance Ltd | Slow release estradiol-progesterone formulation for contraception and hormone replacement therapy |
US20050032811A1 (en) | 2003-08-06 | 2005-02-10 | Josiah Brown | Methods for administering aripiprazole |
ES2535430T3 (es) | 2003-09-03 | 2015-05-11 | Miscon Trading S.A. | Métodos para el tratamiento de la endometriosis |
EP1684782B1 (en) | 2003-10-03 | 2015-09-30 | Thorn BioScience, LLC | Process for the synchronization of ovulation for timed breeding without heat detection |
PL1675573T4 (pl) * | 2003-10-23 | 2016-04-29 | Otsuka Pharma Co Ltd | Sterylny preparat do wstrzykiwań arypiprazolu o kontrolowanym uwalnianiu i sposób |
US7413690B1 (en) | 2003-10-29 | 2008-08-19 | The University Of Mississippi | Process and apparatus for producing spherical pellets using molten solid matrices |
US7491263B2 (en) | 2004-04-05 | 2009-02-17 | Technology Innovation, Llc | Storage assembly |
US7392635B2 (en) * | 2005-06-09 | 2008-07-01 | Tipper Tie, Inc. | Breech loader packaging systems and associated breech loading chutes and methods |
US20070197435A1 (en) * | 2006-02-17 | 2007-08-23 | Webel Stephen K | Process for the synchronization of ovulation for timed breeding without heat detection |
EP2078052B1 (en) | 2006-10-31 | 2010-07-28 | Surmodics Pharmaceuticals, Inc. | Spheronized polymer particles |
JP4879349B2 (ja) | 2007-07-31 | 2012-02-22 | 大塚製薬株式会社 | アリピプラゾール懸濁液及び凍結乾燥製剤の製造方法 |
JP2011516606A (ja) * | 2008-04-14 | 2011-05-26 | ポジ ビジョナリー ソリューションズ エルエルピー | 様々な治療指標に必要な血漿プロゲステロン濃度を得るための方法および医薬組成物 |
CN104906556A (zh) | 2009-04-23 | 2015-09-16 | Jbs联合动物健康二有限公司 | 用于同步授精时间的方法和组合物 |
UY33103A (es) * | 2009-12-15 | 2011-07-29 | Techsphere S A De C V | Formulacion farmaceutica parenteral en suspension, de liberacion sostenida, en dosis baja y ultra baja, en terapia hormonal en el sindrome climaterico |
WO2014085674A1 (en) | 2012-11-28 | 2014-06-05 | Jbs United Animal Health Ii Llc | Method for synchronizing time of insemination in gilts |
WO2017105512A1 (en) | 2015-12-18 | 2017-06-22 | Proinvet Innovations S.A. | Formulations and methods for controlling the reproductive cycle and ovulation |
JP2019506443A (ja) * | 2016-02-24 | 2019-03-07 | イースタン バージニア メディカル スクール | 改良された持効性注射用デポ型ブタン酸レボノルゲストレル懸濁製剤 |
CN106063783B (zh) * | 2016-06-16 | 2019-03-12 | 浙江爱生药业有限公司 | 一种黄体酮缓释微囊制剂及其制备方法 |
US11376220B2 (en) | 2017-06-30 | 2022-07-05 | Therio, LLC | Single-injection methods and formulations to induce and control multiple ovarian follicles in bovine, caprine, ovine, camelid and other female animals |
CN115212170B (zh) * | 2021-04-19 | 2024-01-26 | 中国人民解放军军事科学院军事医学研究院 | 一种致密圆整的药物球形微晶及其制备方法和其应用 |
CN116036022A (zh) * | 2021-12-24 | 2023-05-02 | 中国人民解放军军事科学院军事医学研究院 | 一种新型的含载体材料的药物微球制备及应用 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE670438A (fi) * | 1964-10-06 | 1966-01-31 | ||
US3773919A (en) * | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
US3928566A (en) * | 1970-08-14 | 1975-12-23 | Du Pont | Lyophilized biological products |
JPS5017525A (fi) * | 1973-06-14 | 1975-02-24 | ||
CA1077842A (en) * | 1975-10-09 | 1980-05-20 | Minnesota Mining And Manufacturing Company | Albumin medicament carrier system |
US4244949A (en) * | 1978-04-06 | 1981-01-13 | The Population Council, Inc. | Manufacture of long term contraceptive implant |
US4349580A (en) * | 1978-08-18 | 1982-09-14 | Queen's University At Kingston | Process and solution for preserving green plant tissues |
US4384975A (en) * | 1980-06-13 | 1983-05-24 | Sandoz, Inc. | Process for preparation of microspheres |
US4349530A (en) * | 1980-12-11 | 1982-09-14 | The Ohio State University | Implants, microbeads, microcapsules, preparation thereof and method of administering a biologically-active substance to an animal |
US4963367A (en) * | 1984-04-27 | 1990-10-16 | Medaphore, Inc. | Drug delivery compositions and methods |
IL79407A (en) * | 1985-08-01 | 1991-03-10 | Theragenics Corp | System and method for delivering insoluble material into a living body |
ATE74009T1 (de) * | 1986-08-11 | 1992-04-15 | American Cyanamid Co | Zusammensetzungen zur parenteralen verabreichung und deren verwendung. |
US4837381A (en) * | 1986-08-11 | 1989-06-06 | American Cyanamid Company | Compositions for parenteral administration and their use |
ATE109941T1 (de) * | 1987-04-06 | 1994-09-15 | Endocon Inc | Durch schnellschmelzen hergestellte medizinische implantate. |
US4748024A (en) * | 1987-04-06 | 1988-05-31 | Endocon, Inc. | Flash flow fused medicinal implants |
US4892734A (en) * | 1987-04-06 | 1990-01-09 | Endocon, Inc. | Dispensing paste for forming medicinal pellets |
US5019400A (en) * | 1989-05-01 | 1991-05-28 | Enzytech, Inc. | Very low temperature casting of controlled release microspheres |
ATE99546T1 (de) * | 1989-05-01 | 1994-01-15 | Alkermes Inc | Verfahren zur herstellung von kleinen partikeln von biologisch aktiven molekuelen. |
-
1990
- 1990-06-14 FR FR9007416A patent/FR2663223B1/fr not_active Expired - Fee Related
-
1991
- 1991-06-11 IL IL9845991A patent/IL98459A/en not_active IP Right Cessation
- 1991-06-12 ES ES91910762T patent/ES2059142T3/es not_active Expired - Lifetime
- 1991-06-12 JP JP3510331A patent/JP2675675B2/ja not_active Expired - Lifetime
- 1991-06-12 DK DK91910762.3T patent/DK0533739T3/da active
- 1991-06-12 BR BR919106545A patent/BR9106545A/pt not_active Application Discontinuation
- 1991-06-12 AT AT91910762T patent/ATE109658T1/de not_active IP Right Cessation
- 1991-06-12 KR KR1019920703205A patent/KR0157439B1/ko not_active Expired - Fee Related
- 1991-06-12 EP EP91910762A patent/EP0533739B1/fr not_active Expired - Lifetime
- 1991-06-12 WO PCT/EP1991/001096 patent/WO1991019484A1/fr active IP Right Grant
- 1991-06-12 HU HU9203958A patent/HUT68709A/hu unknown
- 1991-06-12 CA CA002085344A patent/CA2085344C/en not_active Expired - Fee Related
- 1991-06-12 UA UA93004686A patent/UA27043C2/uk unknown
- 1991-06-12 AU AU80847/91A patent/AU661275B2/en not_active Ceased
- 1991-06-12 DE DE69103419T patent/DE69103419T2/de not_active Expired - Fee Related
- 1991-06-12 RU RU92016471A patent/RU2104692C1/ru active
- 1991-06-13 CZ CS19911816A patent/CZ286793B6/cs not_active IP Right Cessation
- 1991-06-13 UY UY23240A patent/UY23240A1/es not_active IP Right Cessation
- 1991-06-13 IE IE201791A patent/IE62679B1/en not_active IP Right Cessation
- 1991-06-13 SK SK1816-91A patent/SK280564B6/sk unknown
- 1991-06-13 US US07/714,583 patent/US5360616A/en not_active Expired - Lifetime
- 1991-06-14 TN TNTNSN91048A patent/TNSN91048A1/fr unknown
- 1991-06-14 PL PL91290677A patent/PL167234B1/pl not_active IP Right Cessation
- 1991-06-14 CN CN91104859A patent/CN1057442C/zh not_active Expired - Fee Related
- 1991-06-14 ZA ZA914550A patent/ZA914550B/xx unknown
- 1991-06-14 NZ NZ238542A patent/NZ238542A/xx not_active IP Right Cessation
- 1991-06-14 PT PT97975A patent/PT97975B/pt not_active IP Right Cessation
-
1992
- 1992-12-11 FI FI925661A patent/FI107698B/fi active
- 1992-12-11 NO NO924792A patent/NO302998B1/no not_active IP Right Cessation
- 1992-12-14 BG BG97166A patent/BG61179B1/bg unknown
-
1994
- 1994-05-17 US US08/243,823 patent/US5512303A/en not_active Expired - Lifetime
-
1996
- 1996-04-15 US US08/632,616 patent/US5633014A/en not_active Expired - Lifetime
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