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DK0482183T3 - Histamin-H3-receptoragonistforbindelser til terapeutisk anvendelse, farmaceutiske sammensætninger virkende som agonister for nævnte receptor og fremstillingsmetode - Google Patents

Histamin-H3-receptoragonistforbindelser til terapeutisk anvendelse, farmaceutiske sammensætninger virkende som agonister for nævnte receptor og fremstillingsmetode

Info

Publication number
DK0482183T3
DK0482183T3 DK91910312.7T DK91910312T DK0482183T3 DK 0482183 T3 DK0482183 T3 DK 0482183T3 DK 91910312 T DK91910312 T DK 91910312T DK 0482183 T3 DK0482183 T3 DK 0482183T3
Authority
DK
Denmark
Prior art keywords
receptor
histamine
compounds
pct
pharmaceutical compositions
Prior art date
Application number
DK91910312.7T
Other languages
English (en)
Inventor
Jean-Charles Schwartz
Jeanne-Marie Lecomte
Monique Garbarg
Jean-Michel Arrang
Walter Schunack
Ralph Lipp
Holger Stark
Original Assignee
Inst Nat Sant Et De La Rech M
Bioprojet Soc Civ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Nat Sant Et De La Rech M, Bioprojet Soc Civ filed Critical Inst Nat Sant Et De La Rech M
Application granted granted Critical
Publication of DK0482183T3 publication Critical patent/DK0482183T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK91910312.7T 1990-05-09 1991-05-10 Histamin-H3-receptoragonistforbindelser til terapeutisk anvendelse, farmaceutiske sammensætninger virkende som agonister for nævnte receptor og fremstillingsmetode DK0482183T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9005776A FR2661909B1 (fr) 1990-05-09 1990-05-09 Nouveaux composes agonistes du recepteur h3 de l'histamine a usage therapeutique, compositions pharmaceutiques agissant comme agonistes dudit recepteur et procede de preparation.

Publications (1)

Publication Number Publication Date
DK0482183T3 true DK0482183T3 (da) 1998-03-09

Family

ID=9396429

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91910312.7T DK0482183T3 (da) 1990-05-09 1991-05-10 Histamin-H3-receptoragonistforbindelser til terapeutisk anvendelse, farmaceutiske sammensætninger virkende som agonister for nævnte receptor og fremstillingsmetode

Country Status (11)

Country Link
US (1) US5342960A (da)
EP (1) EP0482183B1 (da)
JP (1) JP3094384B2 (da)
AT (1) ATE156121T1 (da)
CA (1) CA2063550C (da)
DE (1) DE69127045T2 (da)
DK (1) DK0482183T3 (da)
ES (1) ES2107464T3 (da)
FR (1) FR2661909B1 (da)
GR (1) GR3024991T3 (da)
WO (1) WO1991017146A1 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2078118T3 (es) * 1991-12-18 1995-12-01 Schering Corp Derivados de imidazolil-alquil-piperazina y -diazepina como agonistas/antagonistas de la histamina h3.
US5633250A (en) * 1991-12-18 1997-05-27 Schering Corporation Imidazoylalkyl substituted with a six or seven membered heterocyclic ring containing two nitrogen atoms
US5486526A (en) * 1992-04-01 1996-01-23 The University Of Toledo Histamine H3 -receptor antagonists and therapeutic uses thereof
US5639775A (en) * 1992-04-01 1997-06-17 The University Of Toledo 4-[4'-piperodinyl or 3'-pirrolidinyl] substituted imidazoles as H3 -receptor antagonists and therapeutic uses thereof
BR9306190A (pt) * 1992-04-01 1998-06-23 Univ Toledo Composto composiçao farmacéutica e processo para tratar um indivíduo sofrendo de um distúrbio cognitivo ou uma deficiéncia na atençao ou estímulo
US6407132B1 (en) 1997-07-25 2002-06-18 James Black Foundation Limited Substituted imidazole derivatives and their use as histamine H3 receptor ligands
JP2000189171A (ja) * 1998-12-25 2000-07-11 Banyu Pharmaceut Co Ltd 新規なグアノシン三リン酸（ｇｔｐ）結合タンパク質共役型のレセプタ―タンパク質
WO2000042023A1 (en) 1999-01-18 2000-07-20 Novo Nordisk A/S Substituted imidazoles, their preparation and use
US6908926B1 (en) 1999-04-16 2005-06-21 Novo Nordisk A/S Substituted imidazoles, their preparation and use
US6437147B1 (en) 2000-03-17 2002-08-20 Novo Nordisk Imidazole compounds
US6610721B2 (en) 2000-03-17 2003-08-26 Novo Nordisk A/S Imidazo heterocyclic compounds
JP4344928B2 (ja) * 2002-04-24 2009-10-14 萬有製薬株式会社 ヒスタミン受容体ｈ３常活性変異体およびその利用
CA2606353C (en) 2005-04-28 2011-11-22 Pfizer Limited Alpha-methyl amino acid derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT71653B (en) * 1979-08-15 1982-01-21 Merck & Co Inc Process for preparing allylsulfoxide enzyme inhibitor
FR2548183B1 (fr) * 1983-07-01 1985-10-31 Synthelabo Diphenylazomethines portant un radical imidazolyle, leur preparation et leur application en therapeutique
NL8501093A (nl) * 1985-04-12 1986-11-03 Stamicarbon Werkwijze voor het racemiseren van een optisch aktief n- benzylideenaminozuuramide.
FR2586562B1 (fr) * 1985-09-02 1989-03-10 Inst Nat Sante Rech Med Composition pharmaceutique contenant de l'a-methylhistamine
FR2630328B1 (fr) * 1988-04-22 1990-08-24 Inst Nat Sante Rech Med Derive de l'histamine, sa preparation et son application en therapeutique

Also Published As

Publication number Publication date
FR2661909A1 (fr) 1991-11-15
FR2661909B1 (fr) 1997-08-14
JP3094384B2 (ja) 2000-10-03
GR3024991T3 (en) 1998-01-30
US5342960A (en) 1994-08-30
EP0482183A1 (fr) 1992-04-29
CA2063550C (en) 2002-02-26
CA2063550A1 (en) 1991-11-10
DE69127045T2 (de) 1998-03-05
EP0482183B1 (fr) 1997-07-30
ES2107464T3 (es) 1997-12-01
DE69127045D1 (de) 1997-09-04
ATE156121T1 (de) 1997-08-15
JPH06501241A (ja) 1994-02-10
WO1991017146A1 (fr) 1991-11-14

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