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ATE109658T1 - Injizierbares arzneimittel. - Google Patents

Injizierbares arzneimittel.

Info

Publication number
ATE109658T1
ATE109658T1 AT91910762T AT91910762T ATE109658T1 AT E109658 T1 ATE109658 T1 AT E109658T1 AT 91910762 T AT91910762 T AT 91910762T AT 91910762 T AT91910762 T AT 91910762T AT E109658 T1 ATE109658 T1 AT E109658T1
Authority
AT
Austria
Prior art keywords
microspheres
formulations
contain
dia
microns
Prior art date
Application number
AT91910762T
Other languages
English (en)
Inventor
Garza Flores Josue
Soto Laura P Laiseca
Pichardo Jose Guillen
Uribe Juan Angeles
Original Assignee
Aplicaciones Farmaceuticas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aplicaciones Farmaceuticas filed Critical Aplicaciones Farmaceuticas
Application granted granted Critical
Publication of ATE109658T1 publication Critical patent/ATE109658T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nutrition Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT91910762T 1990-06-14 1991-06-12 Injizierbares arzneimittel. ATE109658T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9007416A FR2663223B1 (fr) 1990-06-14 1990-06-14 Forme galenique parenterale.

Publications (1)

Publication Number Publication Date
ATE109658T1 true ATE109658T1 (de) 1994-08-15

Family

ID=9397598

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91910762T ATE109658T1 (de) 1990-06-14 1991-06-12 Injizierbares arzneimittel.

Country Status (30)

Country Link
US (3) US5360616A (de)
EP (1) EP0533739B1 (de)
JP (1) JP2675675B2 (de)
KR (1) KR0157439B1 (de)
CN (1) CN1057442C (de)
AT (1) ATE109658T1 (de)
AU (1) AU661275B2 (de)
BG (1) BG61179B1 (de)
BR (1) BR9106545A (de)
CA (1) CA2085344C (de)
CZ (1) CZ286793B6 (de)
DE (1) DE69103419T2 (de)
DK (1) DK0533739T3 (de)
ES (1) ES2059142T3 (de)
FI (1) FI107698B (de)
FR (1) FR2663223B1 (de)
HU (1) HUT68709A (de)
IE (1) IE62679B1 (de)
IL (1) IL98459A (de)
NO (1) NO302998B1 (de)
NZ (1) NZ238542A (de)
PL (1) PL167234B1 (de)
PT (1) PT97975B (de)
RU (1) RU2104692C1 (de)
SK (1) SK280564B6 (de)
TN (1) TNSN91048A1 (de)
UA (1) UA27043C2 (de)
UY (1) UY23240A1 (de)
WO (1) WO1991019484A1 (de)
ZA (1) ZA914550B (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2663224B1 (fr) * 1990-06-14 1995-01-20 Applicationes Farmaceuticas Sa Forme galenique parenterale.
NZ260408A (en) 1993-05-10 1996-05-28 Euro Celtique Sa Controlled release preparation comprising tramadol
GB9313642D0 (en) * 1993-07-01 1993-08-18 Glaxo Group Ltd Method and apparatus for the formation of particles
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
FR2732621B1 (fr) * 1995-04-10 1997-06-06 Rhone Poulenc Chimie Perles d'un produit presentant le phenomene de surfusion et leur procede d'obtention
US5904935A (en) * 1995-06-07 1999-05-18 Alza Corporation Peptide/protein suspending formulations
US6028057A (en) * 1998-02-19 2000-02-22 Thorn Bioscience, Llc Regulation of estrus and ovulation in gilts
US6287693B1 (en) * 1998-02-25 2001-09-11 John Claude Savoir Stable shaped particles of crystalline organic compounds
JP2002504505A (ja) * 1998-02-25 2002-02-12 アボット・ラボラトリーズ ブトルファノール持続放出性製剤
CA2382216A1 (en) * 1999-08-20 2001-03-01 Xian Ming Zeng Method to produce powders for pulmonary or nasal administration
US20070254008A1 (en) * 2001-07-13 2007-11-01 Flow Focusing, Inc. Antibiotic formulation and method of treatment
US20070254009A1 (en) * 2001-07-13 2007-11-01 Flow Focusing, Inc. Antibiotic/bone morphogenic protein formulation and method of treatment
US20030055075A1 (en) * 2001-07-13 2003-03-20 Rubsamen Reid M. Programmable controlled release injectable opioid formulation
GB0117696D0 (en) * 2001-07-20 2001-09-12 Bradford Particle Design Plc Particle information
PL1820494T3 (pl) * 2003-06-13 2010-07-30 Skendi Finance Ltd Mikrocząstki składające się z estradiolu i cholesterolu
US20050032811A1 (en) 2003-08-06 2005-02-10 Josiah Brown Methods for administering aripiprazole
KR101288265B1 (ko) 2003-09-03 2013-07-26 미스콘 트레이딩 에스.에이. 자궁 내막증의 치료 방법
WO2005035717A2 (en) 2003-10-03 2005-04-21 Thorn Bioscience, Llc Process for the synchronization of ovulation for timed breeding without heat detection
ES2315721T5 (es) 2003-10-23 2012-08-24 Otsuka Pharmaceutical Co., Ltd. Formulación de aripiprazol inyectable estéril de liberación controlada y procedimiento
US7413690B1 (en) 2003-10-29 2008-08-19 The University Of Mississippi Process and apparatus for producing spherical pellets using molten solid matrices
US7491263B2 (en) 2004-04-05 2009-02-17 Technology Innovation, Llc Storage assembly
US7392635B2 (en) * 2005-06-09 2008-07-01 Tipper Tie, Inc. Breech loader packaging systems and associated breech loading chutes and methods
US20070197435A1 (en) * 2006-02-17 2007-08-23 Webel Stephen K Process for the synchronization of ovulation for timed breeding without heat detection
CA2667890C (en) 2006-10-31 2015-01-27 Surmodics Pharmaceuticals, Inc. Spheronized polymer particles
MX2010001311A (es) 2007-07-31 2010-04-21 Otsuka Pharma Co Ltd Metodo para producir una suspensi?n de aripiprazol y formulacion liofilizada.
JP2011516606A (ja) * 2008-04-14 2011-05-26 ポジ ビジョナリー ソリューションズ エルエルピー 様々な治療指標に必要な血漿プロゲステロン濃度を得るための方法および医薬組成物
CN102596215B (zh) 2009-04-23 2015-04-29 佩纳特克有限责任公司 用于同步授精时间的方法和组合物
UY33103A (es) * 2009-12-15 2011-07-29 Techsphere S A De C V Formulacion farmaceutica parenteral en suspension, de liberacion sostenida, en dosis baja y ultra baja, en terapia hormonal en el sindrome climaterico
ES2808409T3 (es) 2012-11-28 2021-02-26 United Ah Ii Llc Método para sincronizar el tiempo de inseminación en cerdas primerizas
WO2017105512A1 (en) 2015-12-18 2017-06-22 Proinvet Innovations S.A. Formulations and methods for controlling the reproductive cycle and ovulation
AU2017223595B2 (en) 2016-02-24 2022-11-24 Eastern Virginia Medical School An improved formulation of long-acting levonorgestrel butanoate injectable depot suspension
CN106063783B (zh) * 2016-06-16 2019-03-12 浙江爱生药业有限公司 一种黄体酮缓释微囊制剂及其制备方法
US11376220B2 (en) 2017-06-30 2022-07-05 Therio, LLC Single-injection methods and formulations to induce and control multiple ovarian follicles in bovine, caprine, ovine, camelid and other female animals
CN115212170B (zh) * 2021-04-19 2024-01-26 中国人民解放军军事科学院军事医学研究院 一种致密圆整的药物球形微晶及其制备方法和其应用
CN116036022A (zh) * 2021-12-24 2023-05-02 中国人民解放军军事科学院军事医学研究院 一种新型的含载体材料的药物微球制备及应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE670438A (de) * 1964-10-06 1966-01-31
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US3928566A (en) * 1970-08-14 1975-12-23 Du Pont Lyophilized biological products
JPS5017525A (de) * 1973-06-14 1975-02-24
CA1077842A (en) * 1975-10-09 1980-05-20 Minnesota Mining And Manufacturing Company Albumin medicament carrier system
US4244949A (en) * 1978-04-06 1981-01-13 The Population Council, Inc. Manufacture of long term contraceptive implant
US4349580A (en) * 1978-08-18 1982-09-14 Queen's University At Kingston Process and solution for preserving green plant tissues
US4384975A (en) * 1980-06-13 1983-05-24 Sandoz, Inc. Process for preparation of microspheres
US4349530A (en) * 1980-12-11 1982-09-14 The Ohio State University Implants, microbeads, microcapsules, preparation thereof and method of administering a biologically-active substance to an animal
US4963367A (en) * 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
IL79407A (en) * 1985-08-01 1991-03-10 Theragenics Corp System and method for delivering insoluble material into a living body
ATE74009T1 (de) * 1986-08-11 1992-04-15 American Cyanamid Co Zusammensetzungen zur parenteralen verabreichung und deren verwendung.
US4837381A (en) * 1986-08-11 1989-06-06 American Cyanamid Company Compositions for parenteral administration and their use
US4748024A (en) * 1987-04-06 1988-05-31 Endocon, Inc. Flash flow fused medicinal implants
US4892734A (en) * 1987-04-06 1990-01-09 Endocon, Inc. Dispensing paste for forming medicinal pellets
WO1988007816A1 (en) * 1987-04-06 1988-10-20 Endocon, Inc. Flash flow fused medicinal implants
US5019400A (en) * 1989-05-01 1991-05-28 Enzytech, Inc. Very low temperature casting of controlled release microspheres
CA2030551C (en) * 1989-05-01 1998-08-25 Wayne Gombotz Process for producing small particles of biologically active molecules

Also Published As

Publication number Publication date
EP0533739A1 (de) 1993-03-31
SK280564B6 (sk) 2000-03-13
FI925661L (fi) 1992-12-11
NO302998B1 (no) 1998-05-18
DK0533739T3 (da) 1995-01-09
IL98459A0 (en) 1992-07-15
IE912017A1 (en) 1991-12-18
US5360616A (en) 1994-11-01
DE69103419T2 (de) 1995-03-30
EP0533739B1 (de) 1994-08-10
NO924792D0 (no) 1992-12-11
IE62679B1 (en) 1995-02-22
FI107698B (fi) 2001-09-28
AU661275B2 (en) 1995-07-20
WO1991019484A1 (fr) 1991-12-26
HUT68709A (en) 1995-07-28
ES2059142T3 (es) 1994-11-01
NZ238542A (en) 1993-09-27
KR0157439B1 (ko) 1998-11-16
FR2663223B1 (fr) 1994-12-02
CN1057961A (zh) 1992-01-22
CZ286793B6 (cs) 2000-07-12
RU2104692C1 (ru) 1998-02-20
UA27043C2 (uk) 2000-02-28
PL167234B1 (pl) 1995-08-31
TNSN91048A1 (fr) 1992-10-25
FR2663223A1 (fr) 1991-12-20
BG61179B1 (bg) 1997-02-28
DE69103419D1 (de) 1994-09-15
CN1057442C (zh) 2000-10-18
US5512303A (en) 1996-04-30
CA2085344A1 (en) 1991-12-15
BR9106545A (pt) 1993-06-01
IL98459A (en) 1996-09-12
PT97975B (pt) 1998-11-30
NO924792L (no) 1993-02-03
CS181691A3 (en) 1992-06-17
JPH05507694A (ja) 1993-11-04
PT97975A (pt) 1992-04-30
CA2085344C (en) 1998-06-30
US5633014A (en) 1997-05-27
JP2675675B2 (ja) 1997-11-12
HU9203958D0 (en) 1993-03-29
FI925661A0 (fi) 1992-12-11
PL290677A1 (en) 1992-11-30
BG97166A (bg) 1993-12-24
UY23240A1 (es) 1991-07-12
AU8084791A (en) 1992-01-07
ZA914550B (en) 1992-03-25

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee