BG97166A - Лекарствена парентерална форма с депо действие - Google Patents
Лекарствена парентерална форма с депо действие Download PDFInfo
- Publication number
- BG97166A BG97166A BG097166A BG9716692A BG97166A BG 97166 A BG97166 A BG 97166A BG 097166 A BG097166 A BG 097166A BG 9716692 A BG9716692 A BG 9716692A BG 97166 A BG97166 A BG 97166A
- Authority
- BG
- Bulgaria
- Prior art keywords
- parenteral form
- depot action
- medicinal
- medicinal parenteral
- depot
- Prior art date
Links
- VIQCGTZFEYDQMR-UHFFFAOYSA-N fluphenazine decanoate Chemical compound C1CN(CCOC(=O)CCCCCCCCC)CCN1CCCN1C2=CC(C(F)(F)F)=CC=C2SC2=CC=CC=C21 VIQCGTZFEYDQMR-UHFFFAOYSA-N 0.000 title 1
- 239000013543 active substance Substances 0.000 abstract 1
- 230000008018 melting Effects 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
- 239000004005 microsphere Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Nutrition Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
1. Плътна, непорьозна микросфера, характеризираща се с това, че е с диаметър от 1 м до 300 м и съдържа най-малко една инжекционно приложима фармацевтично активна субстанция, без ексципиент, с точка на топене, по-ниска от 600с. 22 претенции, 22 фигури
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9007416A FR2663223B1 (fr) | 1990-06-14 | 1990-06-14 | Forme galenique parenterale. |
| PCT/EP1991/001096 WO1991019484A1 (fr) | 1990-06-14 | 1991-06-12 | Composition pharmaceutique injectable |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG97166A true BG97166A (bg) | 1993-12-24 |
| BG61179B1 BG61179B1 (bg) | 1997-02-28 |
Family
ID=9397598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG97166A BG61179B1 (bg) | 1990-06-14 | 1992-12-14 | Лекарствена парентерална форма с депо действие |
Country Status (30)
| Country | Link |
|---|---|
| US (3) | US5360616A (bg) |
| EP (1) | EP0533739B1 (bg) |
| JP (1) | JP2675675B2 (bg) |
| KR (1) | KR0157439B1 (bg) |
| CN (1) | CN1057442C (bg) |
| AT (1) | ATE109658T1 (bg) |
| AU (1) | AU661275B2 (bg) |
| BG (1) | BG61179B1 (bg) |
| BR (1) | BR9106545A (bg) |
| CA (1) | CA2085344C (bg) |
| CZ (1) | CZ286793B6 (bg) |
| DE (1) | DE69103419T2 (bg) |
| DK (1) | DK0533739T3 (bg) |
| ES (1) | ES2059142T3 (bg) |
| FI (1) | FI107698B (bg) |
| FR (1) | FR2663223B1 (bg) |
| HU (1) | HUT68709A (bg) |
| IE (1) | IE62679B1 (bg) |
| IL (1) | IL98459A (bg) |
| NO (1) | NO302998B1 (bg) |
| NZ (1) | NZ238542A (bg) |
| PL (1) | PL167234B1 (bg) |
| PT (1) | PT97975B (bg) |
| RU (1) | RU2104692C1 (bg) |
| SK (1) | SK280564B6 (bg) |
| TN (1) | TNSN91048A1 (bg) |
| UA (1) | UA27043C2 (bg) |
| UY (1) | UY23240A1 (bg) |
| WO (1) | WO1991019484A1 (bg) |
| ZA (1) | ZA914550B (bg) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2663224B1 (fr) * | 1990-06-14 | 1995-01-20 | Applicationes Farmaceuticas Sa | Forme galenique parenterale. |
| NZ260408A (en) | 1993-05-10 | 1996-05-28 | Euro Celtique Sa | Controlled release preparation comprising tramadol |
| GB9313642D0 (en) * | 1993-07-01 | 1993-08-18 | Glaxo Group Ltd | Method and apparatus for the formation of particles |
| US5965161A (en) | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
| FR2732621B1 (fr) * | 1995-04-10 | 1997-06-06 | Rhone Poulenc Chimie | Perles d'un produit presentant le phenomene de surfusion et leur procede d'obtention |
| US5904935A (en) * | 1995-06-07 | 1999-05-18 | Alza Corporation | Peptide/protein suspending formulations |
| US6028057A (en) * | 1998-02-19 | 2000-02-22 | Thorn Bioscience, Llc | Regulation of estrus and ovulation in gilts |
| US6287693B1 (en) | 1998-02-25 | 2001-09-11 | John Claude Savoir | Stable shaped particles of crystalline organic compounds |
| CA2321924A1 (en) * | 1998-02-25 | 1999-09-02 | Abbott Laboratories | Butorphanol sustained release formulations |
| AU6852900A (en) * | 1999-08-20 | 2001-03-19 | Norton Healthcare Ltd | Method to produce powders for pulmonary or nasal administration |
| US20070254009A1 (en) * | 2001-07-13 | 2007-11-01 | Flow Focusing, Inc. | Antibiotic/bone morphogenic protein formulation and method of treatment |
| US20030055075A1 (en) * | 2001-07-13 | 2003-03-20 | Rubsamen Reid M. | Programmable controlled release injectable opioid formulation |
| US20070254008A1 (en) * | 2001-07-13 | 2007-11-01 | Flow Focusing, Inc. | Antibiotic formulation and method of treatment |
| GB0117696D0 (en) * | 2001-07-20 | 2001-09-12 | Bradford Particle Design Plc | Particle information |
| EP1844765B1 (en) * | 2003-06-13 | 2015-01-21 | Skendi Finance, Ltd. | Slow release estradiol-progesterone formulation |
| US20050032811A1 (en) | 2003-08-06 | 2005-02-10 | Josiah Brown | Methods for administering aripiprazole |
| AU2004267956B2 (en) | 2003-09-03 | 2010-09-16 | Miscon Trading S.A. | Methods for the treatment of endometriosis |
| PT1684782E (pt) | 2003-10-03 | 2015-12-21 | Thorn Bioscience Llc | Processo para a sincronização da ovulação para reprodução regulada sem detecção do cio |
| PT1675573E (pt) | 2003-10-23 | 2008-12-30 | Otsuka Pharma Co Ltd | Formulação de iripiprazole injectável estéril de libertação controlada e um processo para a sua preparação |
| US7413690B1 (en) | 2003-10-29 | 2008-08-19 | The University Of Mississippi | Process and apparatus for producing spherical pellets using molten solid matrices |
| US7491263B2 (en) | 2004-04-05 | 2009-02-17 | Technology Innovation, Llc | Storage assembly |
| US7392635B2 (en) * | 2005-06-09 | 2008-07-01 | Tipper Tie, Inc. | Breech loader packaging systems and associated breech loading chutes and methods |
| US20070197435A1 (en) * | 2006-02-17 | 2007-08-23 | Webel Stephen K | Process for the synchronization of ovulation for timed breeding without heat detection |
| JP5419699B2 (ja) | 2006-10-31 | 2014-02-19 | エボニック コーポレイション | 球状化されたポリマー粒子 |
| JP4879349B2 (ja) | 2007-07-31 | 2012-02-22 | 大塚製薬株式会社 | アリピプラゾール懸濁液及び凍結乾燥製剤の製造方法 |
| US20110104289A1 (en) * | 2008-04-14 | 2011-05-05 | Posi Visionary Solutions Llp | Method and pharmaceutical composition for obtaining the plasmatic progesterone levels required for different therapeutic indications |
| PL2421545T3 (pl) | 2009-04-23 | 2018-05-30 | Jbs United Animal Health Ii Llc | Sposób i kompozycja do synchronizacji czasu inseminacji |
| UY33103A (es) | 2009-12-15 | 2011-07-29 | Techsphere S A De C V | Formulacion farmaceutica parenteral en suspension, de liberacion sostenida, en dosis baja y ultra baja, en terapia hormonal en el sindrome climaterico |
| JP2016508030A (ja) | 2012-11-28 | 2016-03-17 | ジェイビーエス ユナイテッド アニマル ヘルス セカンド エルエルシー | 未経産ブタにおける授精の時期を同期化するための方法および組成物 |
| WO2017105512A1 (en) | 2015-12-18 | 2017-06-22 | Proinvet Innovations S.A. | Formulations and methods for controlling the reproductive cycle and ovulation |
| US12290523B2 (en) | 2016-02-24 | 2025-05-06 | Eastern Virginia Medical School | Formulation of long-acting levonorgestrel butanoate injectable depot suspension |
| CN106063783B (zh) * | 2016-06-16 | 2019-03-12 | 浙江爱生药业有限公司 | 一种黄体酮缓释微囊制剂及其制备方法 |
| US11376220B2 (en) | 2017-06-30 | 2022-07-05 | Therio, LLC | Single-injection methods and formulations to induce and control multiple ovarian follicles in bovine, caprine, ovine, camelid and other female animals |
| CN115212170B (zh) * | 2021-04-19 | 2024-01-26 | 中国人民解放军军事科学院军事医学研究院 | 一种致密圆整的药物球形微晶及其制备方法和其应用 |
| CN116036022A (zh) * | 2021-12-24 | 2023-05-02 | 中国人民解放军军事科学院军事医学研究院 | 一种新型的含载体材料的药物微球制备及应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE670438A (bg) * | 1964-10-06 | 1966-01-31 | ||
| US3773919A (en) * | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US3928566A (en) * | 1970-08-14 | 1975-12-23 | Du Pont | Lyophilized biological products |
| JPS5017525A (bg) * | 1973-06-14 | 1975-02-24 | ||
| CA1077842A (en) * | 1975-10-09 | 1980-05-20 | Minnesota Mining And Manufacturing Company | Albumin medicament carrier system |
| US4244949A (en) * | 1978-04-06 | 1981-01-13 | The Population Council, Inc. | Manufacture of long term contraceptive implant |
| US4349580A (en) * | 1978-08-18 | 1982-09-14 | Queen's University At Kingston | Process and solution for preserving green plant tissues |
| US4384975A (en) * | 1980-06-13 | 1983-05-24 | Sandoz, Inc. | Process for preparation of microspheres |
| US4349530A (en) * | 1980-12-11 | 1982-09-14 | The Ohio State University | Implants, microbeads, microcapsules, preparation thereof and method of administering a biologically-active substance to an animal |
| US4963367A (en) * | 1984-04-27 | 1990-10-16 | Medaphore, Inc. | Drug delivery compositions and methods |
| IL79407A (en) * | 1985-08-01 | 1991-03-10 | Theragenics Corp | System and method for delivering insoluble material into a living body |
| US4837381A (en) * | 1986-08-11 | 1989-06-06 | American Cyanamid Company | Compositions for parenteral administration and their use |
| ES2039219T3 (es) * | 1986-08-11 | 1993-09-16 | American Cyanamid Company | Composiciones para administracion parenteral y su uso. |
| US4892734A (en) * | 1987-04-06 | 1990-01-09 | Endocon, Inc. | Dispensing paste for forming medicinal pellets |
| US4748024A (en) * | 1987-04-06 | 1988-05-31 | Endocon, Inc. | Flash flow fused medicinal implants |
| WO1988007816A1 (en) * | 1987-04-06 | 1988-10-20 | Endocon, Inc. | Flash flow fused medicinal implants |
| US5019400A (en) * | 1989-05-01 | 1991-05-28 | Enzytech, Inc. | Very low temperature casting of controlled release microspheres |
| CA2030551C (en) * | 1989-05-01 | 1998-08-25 | Wayne Gombotz | Process for producing small particles of biologically active molecules |
-
1990
- 1990-06-14 FR FR9007416A patent/FR2663223B1/fr not_active Expired - Fee Related
-
1991
- 1991-06-11 IL IL9845991A patent/IL98459A/en not_active IP Right Cessation
- 1991-06-12 UA UA93004686A patent/UA27043C2/uk unknown
- 1991-06-12 ES ES91910762T patent/ES2059142T3/es not_active Expired - Lifetime
- 1991-06-12 HU HU9203958A patent/HUT68709A/hu unknown
- 1991-06-12 DE DE69103419T patent/DE69103419T2/de not_active Expired - Fee Related
- 1991-06-12 KR KR1019920703205A patent/KR0157439B1/ko not_active Expired - Fee Related
- 1991-06-12 EP EP91910762A patent/EP0533739B1/fr not_active Expired - Lifetime
- 1991-06-12 BR BR919106545A patent/BR9106545A/pt not_active Application Discontinuation
- 1991-06-12 RU RU92016471A patent/RU2104692C1/ru active
- 1991-06-12 AU AU80847/91A patent/AU661275B2/en not_active Ceased
- 1991-06-12 CA CA002085344A patent/CA2085344C/en not_active Expired - Fee Related
- 1991-06-12 AT AT91910762T patent/ATE109658T1/de not_active IP Right Cessation
- 1991-06-12 WO PCT/EP1991/001096 patent/WO1991019484A1/fr not_active Ceased
- 1991-06-12 DK DK91910762.3T patent/DK0533739T3/da active
- 1991-06-12 JP JP3510331A patent/JP2675675B2/ja not_active Expired - Lifetime
- 1991-06-13 CZ CS19911816A patent/CZ286793B6/cs not_active IP Right Cessation
- 1991-06-13 IE IE201791A patent/IE62679B1/en not_active IP Right Cessation
- 1991-06-13 SK SK1816-91A patent/SK280564B6/sk unknown
- 1991-06-13 US US07/714,583 patent/US5360616A/en not_active Expired - Lifetime
- 1991-06-13 UY UY23240A patent/UY23240A1/es not_active IP Right Cessation
- 1991-06-14 PT PT97975A patent/PT97975B/pt not_active IP Right Cessation
- 1991-06-14 CN CN91104859A patent/CN1057442C/zh not_active Expired - Fee Related
- 1991-06-14 PL PL91290677A patent/PL167234B1/pl not_active IP Right Cessation
- 1991-06-14 ZA ZA914550A patent/ZA914550B/xx unknown
- 1991-06-14 NZ NZ238542A patent/NZ238542A/xx not_active IP Right Cessation
- 1991-06-14 TN TNTNSN91048A patent/TNSN91048A1/fr unknown
-
1992
- 1992-12-11 FI FI925661A patent/FI107698B/fi active
- 1992-12-11 NO NO924792A patent/NO302998B1/no not_active IP Right Cessation
- 1992-12-14 BG BG97166A patent/BG61179B1/bg unknown
-
1994
- 1994-05-17 US US08/243,823 patent/US5512303A/en not_active Expired - Lifetime
-
1996
- 1996-04-15 US US08/632,616 patent/US5633014A/en not_active Expired - Lifetime
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BG97166A (bg) | Лекарствена парентерална форма с депо действие | |
| RU92016471A (ru) | Твердая непористая микросфера, способ ее получения и применение в фармакологическом препарате | |
| MX9200667A (es) | Sostenedor de jeringa hipodermica con expulsion en direccion de su eje. | |
| BG95911A (bg) | Лекарствена парентерална форма с депо действие | |
| DE69113847D1 (de) | Injektionsspritze mit angezeigter Dosierung. | |
| DE3868037D1 (de) | Pharmazeutische zusammensetzung mit verzoegerter wirkstoffabgabe. | |
| FR2694290B1 (fr) | Nouvelles phénylimidazolidines éventuellement substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant. | |
| DE3875108D1 (de) | Physiologisch aktives polypeptid und pharmazeutische komposition. | |
| IT8919369A0 (it) | Dispositivo di irradiazione con collettore emettitore ad anello e distributore cilindrico a corone di punte per l'applicazione di luce bianca a scopo terapeutico. | |
| MX9203555A (es) | Sistema intravenoso para administrar un agente benefico y/o farmaco. | |
| ATE98490T1 (de) | Arzneimittel, das einen pharmazeutisch geeigneten traeger sowie die verbindung der struktur (7- alpha, 17-alpha)-17-hydroxy-7-methyl-19-nor-17pregn-5(10)-ene-20-yne-3-one enthaelt. | |
| IT1230703B (it) | Derivati imidazolonici ad attivita' antiipertensiva, loro metodi di preparazione e composizioni farmaceutiche che li contengono. | |
| FR2663827B1 (fr) | Support glissant pour faciliter le deplacement de charges et, notamment, de meubles. | |
| FR2675802B1 (fr) | Antiserotonines, leur preparation et les medicaments les contenant. | |
| DE59001121D1 (en) | Antacidatabletten. | |
| BE832813A (fr) | Ester 9,3",4"-triacyliques de l'antibiotique sf-b37 m1 et leur production | |
| FR2641190B3 (fr) | Injecteur sans aiguille | |
| IT8819791A0 (it) | Peptidi ad attivita' farmaceutica. | |
| IT8919524A0 (it) | Derivati dal 1 arilsolfonil 2 piperidone, loro procedimento di preparazione e loro impiego come farmaci. | |
| IT1222867B (it) | Ftalazino derivati ad attivita' farmaceutica | |
| ES2098263T3 (es) | 8-alfa-acilamino-ergolinas, su preparacion y su utilizacion como medicamentos. | |
| IT9048066A0 (it) | 2- amminotetraline-6, 7-sostituite attive come immunomodulanti e composizioni farmaceutiche che le contengono. | |
| DE3871159D1 (de) | Pharmazeutische und tieraerztliche zusammensetzungen. | |
| IT8820618A0 (it) | Forma farmaceutica e supporto per la somministrazione di estratti ellergenici. | |
| IT8922398A0 (it) | Composizioni farmaceutiche ad elevato assorbimento e stabilita', comprendente una calcitonina come sostanza attiva. |