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EE9900492A - II tüüpi TGF-ß retseptori/immunoglobuliini konstantse piirkonna hübriidvalgud - Google Patents

II tüüpi TGF-ß retseptori/immunoglobuliini konstantse piirkonna hübriidvalgud

Info

Publication number
EE9900492A
EE9900492A EEP199900492A EEP9900492A EE9900492A EE 9900492 A EE9900492 A EE 9900492A EE P199900492 A EEP199900492 A EE P199900492A EE P9900492 A EEP9900492 A EE P9900492A EE 9900492 A EE9900492 A EE 9900492A
Authority
EE
Estonia
Prior art keywords
fusion proteins
tgf
receptor
immunoglobulin constant
type
Prior art date
Application number
EEP199900492A
Other languages
English (en)
Estonian (et)
Inventor
Gotwals Philip
Koteliansky Victor
L. Cate Richard
Sanicola-Nadel Michelle
Original Assignee
Biogen, Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen, Incorporated filed Critical Biogen, Incorporated
Publication of EE9900492A publication Critical patent/EE9900492A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Neurology (AREA)
  • Physics & Mathematics (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
EEP199900492A 1997-04-18 1998-04-16 II tüüpi TGF-ß retseptori/immunoglobuliini konstantse piirkonna hübriidvalgud EE9900492A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4464197P 1997-04-18 1997-04-18
PCT/US1998/007587 WO1998048024A1 (en) 1997-04-18 1998-04-16 Type ii tgf-beta receptor/immunoglobulin constant region fusion proteins

Publications (1)

Publication Number Publication Date
EE9900492A true EE9900492A (et) 2000-06-15

Family

ID=21933495

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP199900492A EE9900492A (et) 1997-04-18 1998-04-16 II tüüpi TGF-ß retseptori/immunoglobuliini konstantse piirkonna hübriidvalgud

Country Status (22)

Country Link
US (1) US20050203022A1 (es)
EP (1) EP0975771B1 (es)
JP (2) JP2001515360A (es)
KR (1) KR20010006534A (es)
CN (1) CN1257545A (es)
AT (1) ATE366816T1 (es)
AU (1) AU737106B2 (es)
BR (1) BR9808934A (es)
CA (1) CA2286933A1 (es)
DE (1) DE69838061T2 (es)
DK (1) DK0975771T3 (es)
EA (1) EA199900947A1 (es)
EE (1) EE9900492A (es)
ES (1) ES2289778T3 (es)
IL (1) IL132249A0 (es)
IS (1) IS5217A (es)
NO (1) NO994998L (es)
NZ (1) NZ500284A (es)
PL (1) PL336306A1 (es)
PT (1) PT975771E (es)
TR (1) TR199902878T2 (es)
WO (1) WO1998048024A1 (es)

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US6537776B1 (en) 1999-06-14 2003-03-25 Diversa Corporation Synthetic ligation reassembly in directed evolution
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US6492325B1 (en) 1998-05-22 2002-12-10 Boys Town National Research Hospital Use of α1β1 integrin receptor inhibitors and TGF-β1 inhibitors in the treatment of kidney disease
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US6808902B1 (en) 1999-11-12 2004-10-26 Amgen Inc. Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
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KR101245983B1 (ko) 2004-03-31 2013-06-28 제넨테크, 인크. 인간화 항-tgf-베타 항체
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Also Published As

Publication number Publication date
DK0975771T3 (da) 2007-10-22
CA2286933A1 (en) 1998-10-29
ES2289778T3 (es) 2008-02-01
AU737106B2 (en) 2001-08-09
JP2001515360A (ja) 2001-09-18
AU7120898A (en) 1998-11-13
EP0975771B1 (en) 2007-07-11
DE69838061T2 (de) 2008-03-13
NZ500284A (en) 2001-09-28
KR20010006534A (ko) 2001-01-26
JP2008106076A (ja) 2008-05-08
WO1998048024A1 (en) 1998-10-29
PL336306A1 (en) 2000-06-19
EA199900947A1 (ru) 2000-04-24
NO994998L (no) 1999-12-20
CN1257545A (zh) 2000-06-21
IL132249A0 (en) 2001-03-19
DE69838061D1 (de) 2007-08-23
EP0975771A1 (en) 2000-02-02
NO994998D0 (no) 1999-10-14
US20050203022A1 (en) 2005-09-15
ATE366816T1 (de) 2007-08-15
TR199902878T2 (xx) 2000-02-21
IS5217A (is) 1999-10-15
BR9808934A (pt) 2000-08-01
PT975771E (pt) 2007-10-01

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