ECSP10010644A - Inmunoglobulinas duales de dominio variable y sus aplicaciones - Google Patents
Inmunoglobulinas duales de dominio variable y sus aplicacionesInfo
- Publication number
- ECSP10010644A ECSP10010644A EC2010010644A ECSP10010644A ECSP10010644A EC SP10010644 A ECSP10010644 A EC SP10010644A EC 2010010644 A EC2010010644 A EC 2010010644A EC SP10010644 A ECSP10010644 A EC SP10010644A EC SP10010644 A ECSP10010644 A EC SP10010644A
- Authority
- EC
- Ecuador
- Prior art keywords
- immunoglobulins
- applications
- variable domain
- domain dual
- dual
- Prior art date
Links
- 108060003951 Immunoglobulin Proteins 0.000 title 1
- 230000009977 dual effect Effects 0.000 title 1
- 102000018358 immunoglobulin Human genes 0.000 title 1
- 229940072221 immunoglobulins Drugs 0.000 title 1
- 102000014914 Carrier Proteins Human genes 0.000 abstract 1
- 108091008324 binding proteins Proteins 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6845—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a cytokine, e.g. growth factors, VEGF, TNF, a lymphokine or an interferon
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07—ORGANIC CHEMISTRY
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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Abstract
La presente invención se refiere a la ingeniería de proteínas de unión multivalentes y multiespecíficas, métodos de fabricación, y específicamente para su uso en la prevención, el diagnóstico y/o tratamiento de la enfermedad.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13081708P | 2008-06-03 | 2008-06-03 | |
| US19717208P | 2008-10-23 | 2008-10-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP10010644A true ECSP10010644A (es) | 2011-02-28 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2010010644A ECSP10010644A (es) | 2008-06-03 | 2010-11-29 | Inmunoglobulinas duales de dominio variable y sus aplicaciones |
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| US (3) | US9035027B2 (es) |
| EP (2) | EP3002299A1 (es) |
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| KR (1) | KR20110016958A (es) |
| CN (1) | CN102112495A (es) |
| AR (1) | AR072001A1 (es) |
| AU (1) | AU2009256250B2 (es) |
| BR (1) | BRPI0913406A2 (es) |
| CA (1) | CA2726087A1 (es) |
| CL (1) | CL2010001427A1 (es) |
| CO (1) | CO6331347A2 (es) |
| CR (1) | CR11837A (es) |
| DO (1) | DOP2010000368A (es) |
| EC (1) | ECSP10010644A (es) |
| IL (1) | IL209529A0 (es) |
| MX (1) | MX2010013239A (es) |
| NO (1) | NO20101692A1 (es) |
| NZ (1) | NZ589434A (es) |
| PE (1) | PE20100092A1 (es) |
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| SG (1) | SG191639A1 (es) |
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| WO (1) | WO2009149189A2 (es) |
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- 2009-06-03 AR ARP090101994A patent/AR072001A1/es not_active Application Discontinuation
- 2009-06-03 UY UY0001031862A patent/UY31862A/es not_active Application Discontinuation
- 2009-06-03 CA CA2726087A patent/CA2726087A1/en not_active Abandoned
- 2009-06-03 NZ NZ589434A patent/NZ589434A/xx not_active IP Right Cessation
- 2009-06-03 TW TW098118450A patent/TW201008580A/zh unknown
- 2009-06-03 SG SG2013042916A patent/SG191639A1/en unknown
- 2009-06-03 EP EP09759348A patent/EP2297209A4/en not_active Withdrawn
- 2009-06-03 KR KR1020107029457A patent/KR20110016958A/ko not_active Withdrawn
- 2009-06-03 BR BRPI0913406A patent/BRPI0913406A2/pt not_active IP Right Cessation
- 2009-06-03 AU AU2009256250A patent/AU2009256250B2/en not_active Ceased
- 2009-06-03 WO PCT/US2009/046137 patent/WO2009149189A2/en not_active Ceased
- 2009-06-03 RU RU2010153580/10A patent/RU2010153580A/ru not_active Application Discontinuation
-
2010
- 2010-11-23 IL IL209529A patent/IL209529A0/en unknown
- 2010-11-29 ZA ZA2010/08560A patent/ZA201008560B/en unknown
- 2010-11-29 EC EC2010010644A patent/ECSP10010644A/es unknown
- 2010-11-30 DO DO2010000368A patent/DOP2010000368A/es unknown
- 2010-11-30 CO CO10150956A patent/CO6331347A2/es not_active Application Discontinuation
- 2010-12-03 NO NO20101692A patent/NO20101692A1/no not_active Application Discontinuation
- 2010-12-09 CR CR11837A patent/CR11837A/es not_active Application Discontinuation
- 2010-12-10 CL CL2010001427A patent/CL2010001427A1/es unknown
-
2014
- 2014-04-08 US US14/248,223 patent/US20140335014A1/en not_active Abandoned
-
2015
- 2015-04-15 US US14/687,392 patent/US20150315283A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| SG191639A1 (en) | 2013-07-31 |
| NO20101692A1 (no) | 2011-03-03 |
| IL209529A0 (en) | 2011-01-31 |
| TW201008580A (en) | 2010-03-01 |
| US20090311253A1 (en) | 2009-12-17 |
| CL2010001427A1 (es) | 2011-07-15 |
| BRPI0913406A2 (pt) | 2018-01-09 |
| KR20110016958A (ko) | 2011-02-18 |
| WO2009149189A3 (en) | 2010-03-04 |
| AU2009256250A1 (en) | 2009-12-10 |
| ZA201008560B (en) | 2014-05-28 |
| EP2297209A4 (en) | 2012-08-01 |
| MX2010013239A (es) | 2011-02-24 |
| EP2297209A2 (en) | 2011-03-23 |
| US20150315283A1 (en) | 2015-11-05 |
| US9035027B2 (en) | 2015-05-19 |
| DOP2010000368A (es) | 2011-02-15 |
| PE20100092A1 (es) | 2010-03-12 |
| CR11837A (es) | 2011-01-12 |
| CA2726087A1 (en) | 2009-12-10 |
| AR072001A1 (es) | 2010-07-28 |
| CN102112495A (zh) | 2011-06-29 |
| JP2011523853A (ja) | 2011-08-25 |
| RU2010153580A (ru) | 2012-07-20 |
| EP3002299A1 (en) | 2016-04-06 |
| UY31862A (es) | 2010-01-05 |
| WO2009149189A2 (en) | 2009-12-10 |
| US20140335014A1 (en) | 2014-11-13 |
| CO6331347A2 (es) | 2011-10-20 |
| NZ589434A (en) | 2012-11-30 |
| AU2009256250B2 (en) | 2013-05-30 |
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