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DE60324805D1 - Inhibitoren von tyrosinkinasen - Google Patents

Inhibitoren von tyrosinkinasen

Info

Publication number
DE60324805D1
DE60324805D1 DE60324805T DE60324805T DE60324805D1 DE 60324805 D1 DE60324805 D1 DE 60324805D1 DE 60324805 T DE60324805 T DE 60324805T DE 60324805 T DE60324805 T DE 60324805T DE 60324805 D1 DE60324805 D1 DE 60324805D1
Authority
DE
Germany
Prior art keywords
inhibitors
tyrosine kinases
kinases
tyrosine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60324805T
Other languages
English (en)
Inventor
Werner Breitenstein
Pascal Furet
Sandra Jacob
Paul William Manley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32178870&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60324805(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Application granted granted Critical
Publication of DE60324805D1 publication Critical patent/DE60324805D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60324805T 2002-07-05 2003-07-04 Inhibitoren von tyrosinkinasen Expired - Lifetime DE60324805D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0215676.8A GB0215676D0 (en) 2002-07-05 2002-07-05 Organic compounds
GBGB0229893.3A GB0229893D0 (en) 2002-07-05 2002-12-20 Organic compounds
PCT/EP2003/007198 WO2004005281A1 (en) 2002-07-05 2003-07-04 Inhibitors of tyrosine kinases

Publications (1)

Publication Number Publication Date
DE60324805D1 true DE60324805D1 (de) 2009-01-02

Family

ID=32178870

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60324805T Expired - Lifetime DE60324805D1 (de) 2002-07-05 2003-07-04 Inhibitoren von tyrosinkinasen

Country Status (30)

Country Link
US (5) US7169791B2 (de)
EP (4) EP2368889A1 (de)
JP (4) JP4110140B2 (de)
KR (2) KR100733639B1 (de)
CN (2) CN101045727A (de)
AR (1) AR040390A1 (de)
AT (1) ATE414699T1 (de)
AU (1) AU2003249962C9 (de)
BR (1) BRPI0312464B8 (de)
CA (3) CA2677313C (de)
CO (1) CO5680432A2 (de)
CY (1) CY1108813T1 (de)
DE (1) DE60324805D1 (de)
DK (1) DK1532138T3 (de)
EC (1) ECSP055525A (de)
ES (2) ES2475066T3 (de)
GB (2) GB0215676D0 (de)
IL (2) IL165977A (de)
MX (1) MXPA05000328A (de)
MY (1) MY143466A (de)
NO (1) NO331166B1 (de)
NZ (1) NZ537396A (de)
PE (1) PE20040647A1 (de)
PL (3) PL395096A1 (de)
PT (2) PT2357182E (de)
RU (2) RU2348627C2 (de)
SI (1) SI1532138T1 (de)
TW (1) TWI313603B (de)
WO (1) WO2004005281A1 (de)
ZA (1) ZA200410322B (de)

Families Citing this family (360)

* Cited by examiner, † Cited by third party
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ES2421587T3 (es) 2005-05-02 2013-09-04 Novartis Ag Uso de derivados de pirimidilaminobenzamida para el tratamiento de mastocitosis sistémica
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ATE414699T1 (de) 2008-12-15
CN1675195A (zh) 2005-09-28
BRPI0312464B8 (pt) 2021-05-25
CA2677315A1 (en) 2004-01-15
RU2008137927A (ru) 2010-03-27
US20080188451A1 (en) 2008-08-07
EP1532138B1 (de) 2008-11-19
HK1077811A1 (en) 2006-02-24
JP2008044968A (ja) 2008-02-28
AU2003249962A1 (en) 2004-01-23
NZ537396A (en) 2006-11-30
MY143466A (en) 2011-05-31
US7169791B2 (en) 2007-01-30
ZA200410322B (en) 2006-07-26
JP4895976B2 (ja) 2012-03-14
US7569566B2 (en) 2009-08-04
JP4110140B2 (ja) 2008-07-02
PE20040647A1 (es) 2004-11-15
KR100733639B1 (ko) 2007-06-29
MXPA05000328A (es) 2005-03-31
TW200403060A (en) 2004-03-01
CY1108813T1 (el) 2014-04-09
ES2475066T3 (es) 2014-07-10
ES2318164T3 (es) 2009-05-01
BR0312464A (pt) 2005-05-03
AU2003249962C9 (en) 2022-06-30
IL198996A0 (en) 2011-08-01
NO20050636L (no) 2005-02-04
PL374583A1 (en) 2005-10-31

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