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BRPI0511321A - moduladores de transportadores de cassete de ligação de atp - Google Patents

moduladores de transportadores de cassete de ligação de atp

Info

Publication number
BRPI0511321A
BRPI0511321A BRPI0511321-0A BRPI0511321A BRPI0511321A BR PI0511321 A BRPI0511321 A BR PI0511321A BR PI0511321 A BRPI0511321 A BR PI0511321A BR PI0511321 A BRPI0511321 A BR PI0511321A
Authority
BR
Brazil
Prior art keywords
modulators
atp
cassette carrier
carrier modulators
methods
Prior art date
Application number
BRPI0511321-0A
Other languages
English (en)
Inventor
Sarah S Hadida Ruah
Anna R Hazlewood
Peter D J Grootenhuis
Frederick F Van Goor
Ashvani K Singh
Jinglan Zhou
Jason Mccartney
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35429349&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0511321(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vertex Pharma filed Critical Vertex Pharma
Priority to BR122018075478A priority Critical patent/BR122018075478B8/pt
Publication of BRPI0511321A publication Critical patent/BRPI0511321A/pt
Publication of BRPI0511321B1 publication Critical patent/BRPI0511321B1/pt
Publication of BRPI0511321B8 publication Critical patent/BRPI0511321B8/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
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Abstract

MODULADORES DE TRANSPORTADORES DE CASSETE DE LIGAçãO DE ATP. A presente invenção refere-se a moduladores de transportadores de Cassete de Ligação de ATP ("ABC") ou fragmento deste, incluindo reguladores de condutância de Transmembrana de Fibrose Cística, composições deste, e métodos com isto. A presente invenção da mesma forma se refere aos métodos de tratar doenças mediadas por transportador de ABC empregando-se tais moduladores.
BRPI0511321A 2004-06-24 2005-06-24 moduladores de transportadores de cassete de ligação de atp, composição farmacêutica e seus usos BRPI0511321B8 (pt)

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US58267604P 2004-06-24 2004-06-24
US60/582,676 2004-06-24
US63012704P 2004-11-22 2004-11-22
US60/630,127 2004-11-22
US63567404P 2004-12-13 2004-12-13
US60/635,674 2004-12-13
US65821905P 2005-03-03 2005-03-03
US60/658,219 2005-03-03
US66131105P 2005-03-11 2005-03-11
US60/661,311 2005-03-11
PCT/US2005/022768 WO2006002421A2 (en) 2004-06-24 2005-06-24 Modulators of atp-binding cassette transporters

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CA2881078A1 (en) 2006-01-05
PL2502911T3 (pl) 2017-09-29
AU2010249302B2 (en) 2013-01-17
EP1773816B1 (en) 2015-01-07
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JP2008504291A (ja) 2008-02-14
US10662192B2 (en) 2020-05-26
LT2502911T (lt) 2017-09-11
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AU2010251787B2 (en) 2012-08-16
ES2786563T3 (es) 2020-10-13
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IL213155A0 (en) 2011-07-31
JP2012056963A (ja) 2012-03-22
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US8741925B2 (en) 2014-06-03
CN104788328B (zh) 2017-09-12
BRPI0511321B8 (pt) 2021-05-25
ME02156B (me) 2015-10-20
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US20150065487A1 (en) 2015-03-05
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US20140051724A1 (en) 2014-02-20
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