ATE442866T1 - Fusionsproteine aus mycobakterium tuberculosis - Google Patents
Fusionsproteine aus mycobakterium tuberculosisInfo
- Publication number
- ATE442866T1 ATE442866T1 AT01946661T AT01946661T ATE442866T1 AT E442866 T1 ATE442866 T1 AT E442866T1 AT 01946661 T AT01946661 T AT 01946661T AT 01946661 T AT01946661 T AT 01946661T AT E442866 T1 ATE442866 T1 AT E442866T1
- Authority
- AT
- Austria
- Prior art keywords
- fusion proteins
- compositions
- mycobacterium tuberculosis
- tuberculosis
- mycobacterium
- Prior art date
Links
- 102000037865 fusion proteins Human genes 0.000 title abstract 3
- 108020001507 fusion proteins Proteins 0.000 title abstract 3
- 241000187479 Mycobacterium tuberculosis Species 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- 201000008827 tuberculosis Diseases 0.000 abstract 2
- 241000187488 Mycobacterium sp. Species 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000035945 sensitivity Effects 0.000 abstract 1
- 230000000405 serological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/597,796 US7186412B1 (en) | 1998-04-07 | 2000-06-20 | Fusion proteins of Mycobacterium tuberculosis |
US26573701P | 2001-02-01 | 2001-02-01 | |
PCT/US2001/019959 WO2001098460A2 (en) | 2000-06-20 | 2001-06-20 | Fusion proteins of mycobacterium tuberculosis |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE442866T1 true ATE442866T1 (de) | 2009-10-15 |
Family
ID=40253655
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01946661T ATE442866T1 (de) | 2000-06-20 | 2001-06-20 | Fusionsproteine aus mycobakterium tuberculosis |
AT09170183T ATE526994T1 (de) | 2000-06-20 | 2001-06-20 | Mtb32a antigen aus mycobakterium tuberculosis mit inaktivierter protease aktivität und fusionsproteine die das antigen enthalten |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT09170183T ATE526994T1 (de) | 2000-06-20 | 2001-06-20 | Mtb32a antigen aus mycobakterium tuberculosis mit inaktivierter protease aktivität und fusionsproteine die das antigen enthalten |
Country Status (14)
Country | Link |
---|---|
US (7) | US7083796B2 (de) |
EP (2) | EP2133100B1 (de) |
JP (2) | JP5139618B2 (de) |
AT (2) | ATE442866T1 (de) |
AU (2) | AU2001268678B2 (de) |
CA (1) | CA2413959C (de) |
CY (2) | CY1109531T1 (de) |
DE (1) | DE60139963D1 (de) |
DK (2) | DK2133100T3 (de) |
ES (2) | ES2333579T3 (de) |
HK (1) | HK1080506A1 (de) |
PT (2) | PT1542732E (de) |
SI (1) | SI1542732T1 (de) |
WO (1) | WO2001098460A2 (de) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6458366B1 (en) | 1995-09-01 | 2002-10-01 | Corixa Corporation | Compounds and methods for diagnosis of tuberculosis |
US6290969B1 (en) * | 1995-09-01 | 2001-09-18 | Corixa Corporation | Compounds and methods for immunotherapy and diagnosis of tuberculosis |
US6592877B1 (en) * | 1995-09-01 | 2003-07-15 | Corixa Corporation | Compounds and methods for immunotherapy and diagnosis of tuberculosis |
US8143386B2 (en) * | 1999-04-07 | 2012-03-27 | Corixa Corporation | Fusion proteins of mycobacterium tuberculosis antigens and their uses |
JP2003527830A (ja) * | 1999-10-07 | 2003-09-24 | コリクサ コーポレイション | 異種タンパク質の安定かつ高収量の発現を容易にするための、Mycobacteriumtuberculosisをコードする配列を使用する方法 |
JP2003510370A (ja) * | 1999-10-07 | 2003-03-18 | コリクサ コーポレイション | Mycobacteriumtuberculosisの融合タンパク質 |
WO2001062893A2 (en) * | 2000-02-25 | 2001-08-30 | Corixa Corporation | Compounds and methods for diagnosis and immunotherapy of tuberculosis |
ATE442866T1 (de) * | 2000-06-20 | 2009-10-15 | Corixa Corp | Fusionsproteine aus mycobakterium tuberculosis |
US7026465B2 (en) * | 2002-02-15 | 2006-04-11 | Corixa Corporation | Fusion proteins of Mycobacterium tuberculosis |
SG159554A1 (en) | 2004-11-16 | 2010-03-30 | Crucell Holland Bv | Multivalent vaccines comprising recombinant viral vectors |
AU2011224145B2 (en) * | 2005-04-29 | 2013-05-16 | Glaxosmithkline Biologicals S.A. | Novel method for preventing or treating M tuberculosis infection |
UA107788C2 (en) * | 2005-04-29 | 2015-02-25 | Glaxosmithkline Biolog Sa | A fusion protein of m. tuberculosis |
SI2426141T1 (sl) * | 2005-04-29 | 2015-01-30 | Glaxosmithkline Biologicals S.A. | Postopek za preprečevanje ali zdravljenje infekcije z M tuberculosis |
US8475803B2 (en) | 2005-04-29 | 2013-07-02 | Fusion Antibodies Limited | Assays for diagnosis of tuberculosis and uses thereof |
US20070081944A1 (en) * | 2005-09-30 | 2007-04-12 | Reed Steven G | Iontophoresis apparatus and method for the diagnosis of tuberculosis |
JP5378350B2 (ja) | 2007-04-04 | 2013-12-25 | インフェクティアス ディジーズ リサーチ インスティチュート | 結核菌(Mycobacteriumtuberculosis)ポリペプチドおよびその融合物を含む免疫原性組成物 |
US7732580B2 (en) * | 2007-10-13 | 2010-06-08 | Cornell University | Compositions for eliciting an immune response against Mycobacterium avium subspecies paratuberculosis |
KR101378240B1 (ko) * | 2008-02-22 | 2014-03-28 | 포항공과대학교 산학협력단 | 결핵 예방용 조성물 |
BRPI0916703A2 (pt) * | 2008-07-25 | 2019-12-24 | Glaxo Group Ltd | usos de um polipeptídeo, e de um polinucleotídeo, e, composição |
PT2315597T (pt) | 2008-07-25 | 2017-11-20 | Glaxosmithkline Biologicals Sa | Novas composições e métodos |
EA201100070A1 (ru) | 2008-07-25 | 2011-10-31 | Глаксо Груп Лимитед | Туберкулезный белок rv2386c, композиции и их применения |
CN102869372B (zh) | 2010-01-27 | 2016-01-20 | 葛兰素史密丝克莱恩生物有限公司 | 经修饰的结核抗原 |
UA110806C2 (uk) | 2010-12-14 | 2016-02-25 | Ґлаксосмітклайн Байолоджікалз С.А. | Мікобактеріальна антигенна композиція |
EP2771469A4 (de) * | 2011-10-24 | 2015-04-08 | Univ Central Florida Res Found | An choleratoxin-b-untereinheit kondeniserte plastid-exprimierte mycobacterium-tuberkuloseimpfstoffantigene esat-6 und mtb72f |
US9404923B2 (en) | 2012-02-07 | 2016-08-02 | Intuitive Biosciences, Inc. | Mycobacterium tuberculosis specific peptides for detection of infection or immunization in non-human primates |
MX347154B (es) | 2012-02-24 | 2017-02-21 | Centro De Investigación Científica Y De Educación Superior De Ensenada Baja California (Cicese) | Prueba de diagnóstico para enfermedades infecciosas en ganado bovino. |
GB201513176D0 (en) * | 2015-07-27 | 2015-09-09 | Glaxosmithkline Biolog Sa | Novel methods for inducing an immune response |
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