NO329875B1 - Isolert DNA-sekvens som koder for svinereproduktive- og respiratoriske syndromvirus (PRRSV), en sammensetning omfattende polypeptidene kodet av denne, en sammensetning for indusering av antistoffer mot PRRSV, anvendelse av sammensetning for fremstilling av vaksine og fremgangsmate for a skille PRRSV-stamme ISU-55 fra andre PRRSV-stammer. - Google Patents
Isolert DNA-sekvens som koder for svinereproduktive- og respiratoriske syndromvirus (PRRSV), en sammensetning omfattende polypeptidene kodet av denne, en sammensetning for indusering av antistoffer mot PRRSV, anvendelse av sammensetning for fremstilling av vaksine og fremgangsmate for a skille PRRSV-stamme ISU-55 fra andre PRRSV-stammer.Info
- Publication number
- NO329875B1 NO329875B1 NO20003526A NO20003526A NO329875B1 NO 329875 B1 NO329875 B1 NO 329875B1 NO 20003526 A NO20003526 A NO 20003526A NO 20003526 A NO20003526 A NO 20003526A NO 329875 B1 NO329875 B1 NO 329875B1
- Authority
- NO
- Norway
- Prior art keywords
- prrsv
- composition
- methods
- respiratory syndrome
- syndrome virus
- Prior art date
Links
- 241001135989 Porcine reproductive and respiratory syndrome virus Species 0.000 title abstract 9
- 229920001184 polypeptide Polymers 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 title 1
- 241000282898 Sus scrofa Species 0.000 title 1
- 241000700605 Viruses Species 0.000 title 1
- 230000001939 inductive effect Effects 0.000 title 1
- 230000001850 reproductive effect Effects 0.000 title 1
- 230000000241 respiratory effect Effects 0.000 title 1
- 208000011580 syndromic disease Diseases 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 102000004169 proteins and genes Human genes 0.000 abstract 4
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 108700026244 Open Reading Frames Proteins 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Mycology (AREA)
- General Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/019,793 US6380376B1 (en) | 1992-10-30 | 1998-02-06 | Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV) |
PCT/US1999/002630 WO1999039582A1 (en) | 1998-02-06 | 1999-02-08 | Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (prrsv) |
Publications (3)
Publication Number | Publication Date |
---|---|
NO20003526D0 NO20003526D0 (no) | 2000-07-07 |
NO20003526L NO20003526L (no) | 2000-09-26 |
NO329875B1 true NO329875B1 (no) | 2011-01-17 |
Family
ID=21795057
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20003526A NO329875B1 (no) | 1998-02-06 | 2000-07-07 | Isolert DNA-sekvens som koder for svinereproduktive- og respiratoriske syndromvirus (PRRSV), en sammensetning omfattende polypeptidene kodet av denne, en sammensetning for indusering av antistoffer mot PRRSV, anvendelse av sammensetning for fremstilling av vaksine og fremgangsmate for a skille PRRSV-stamme ISU-55 fra andre PRRSV-stammer. |
Country Status (13)
Country | Link |
---|---|
US (3) | US6380376B1 (no) |
EP (1) | EP1047301B1 (no) |
JP (2) | JP2002504317A (no) |
KR (2) | KR100696339B1 (no) |
AT (1) | ATE371373T1 (no) |
AU (1) | AU743212B2 (no) |
BR (1) | BR9908615A (no) |
CA (2) | CA2751655C (no) |
DE (1) | DE69936977T2 (no) |
ES (1) | ES2294834T3 (no) |
HK (1) | HK1032511A1 (no) |
NO (1) | NO329875B1 (no) |
WO (1) | WO1999039582A1 (no) |
Families Citing this family (31)
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CA2103460C (en) * | 1991-06-06 | 2000-09-26 | Gert Wensvoort | Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits |
US5695766A (en) * | 1992-10-30 | 1997-12-09 | Iowa State University Research Foundation | Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome |
US6380376B1 (en) * | 1992-10-30 | 2002-04-30 | Iowa State University Research Foundation | Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV) |
US6592873B1 (en) * | 1992-10-30 | 2003-07-15 | Iowa State University Research Foundation, Inc. | Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids |
US20040224327A1 (en) * | 1996-10-30 | 2004-11-11 | Meulenberg Johanna Jacoba Maria | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
EP0839912A1 (en) * | 1996-10-30 | 1998-05-06 | Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
PL204373B1 (pl) * | 1999-03-08 | 2010-01-29 | Boehringer Ingelheim Vetemendi | Replikony zespołu reprodukcyjnego i oddechowego świń (PRRSV), zastosowanie replikonów PRRSV, szczepionki zawierające replikony PRRSV i zastosowanie tych szczepionek |
JP4778620B2 (ja) * | 1999-04-22 | 2011-09-21 | ユナイテッド ステイツ デパートメント オブ アグリカルチャー | 分離株ja−142に基づく、豚繁殖・呼吸障害症候群ワクチン |
US6951605B2 (en) * | 2002-10-08 | 2005-10-04 | Exxonmobil Research And Engineering Company | Method for making lube basestocks |
AU2005265142A1 (en) * | 2004-06-18 | 2006-01-26 | Regents Of The University Of Minnesota | Identifying virally infected and vaccinated organisms |
US7632636B2 (en) * | 2004-09-21 | 2009-12-15 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome isolates and methods of use |
WO2006093797A2 (en) | 2005-02-28 | 2006-09-08 | Mj Biologics, Inc. | Method and kit for detecting porcine reproductive and respiratory syndrome virus |
ES2603553T3 (es) | 2005-06-24 | 2017-02-28 | Regents Of The University Of Minnesota | Virus PRRS, clones infecciosos, mutantes de los mismos, y métodos de uso |
US7241582B2 (en) * | 2005-07-05 | 2007-07-10 | Mj Biologics, Inc. | Diagnostic test kits |
EP1962900A2 (en) * | 2005-11-29 | 2008-09-03 | Iowa State University Research Foundation, Inc. | Identification of protective antigenic determinants of porcine reproductive and respiratory syndrome virus (prrsv) and uses thereof |
WO2010025109A1 (en) * | 2008-08-25 | 2010-03-04 | Boehringer Ingelheim Vetmedia, Inc. | Vaccine against highly pathogenic porcine reproductive and respiratory syndrome (hp prrs) |
AR078253A1 (es) * | 2009-09-02 | 2011-10-26 | Boehringer Ingelheim Vetmed | Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad |
PH12013501708B1 (en) | 2011-02-17 | 2018-08-03 | Boehringer Ingelheim Vetmedica Gmbh | Commercial scale process for production of prrsv |
DK2959916T3 (en) | 2011-02-17 | 2018-10-29 | Boehringer Ingelheim Vetmedica Gmbh | New European PRRSV strain. |
US9187731B2 (en) | 2011-07-29 | 2015-11-17 | Boehringer Ingelheim Vetmedica Gmbh | PRRS virus inducing type I interferon in susceptible cells |
WO2013017568A1 (en) | 2011-07-29 | 2013-02-07 | Boehringer Ingelheim Vetmedica Gmbh | INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF |
UA114503C2 (uk) | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv та mycoplasma hyopneumoniae |
US9120859B2 (en) | 2012-04-04 | 2015-09-01 | Zoetis Services Llc | Mycoplasma hyopneumoniae vaccine |
UA114504C2 (uk) | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs |
KR20150020209A (ko) * | 2012-05-17 | 2015-02-25 | 조에티스 엘엘씨 | 이유 전 돼지 생식기 호흡기 증후군(prrs) 바이러스에 대한 효과적인 백신접종 |
WO2014150822A2 (en) | 2013-03-15 | 2014-09-25 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use |
WO2015140774A1 (en) * | 2014-03-21 | 2015-09-24 | Nutech Ventures | A non-naturally occuring porcine reproductive and respiratory syndrome virus (prrsv) and methods of using |
US9981033B2 (en) * | 2015-06-23 | 2018-05-29 | Merial Inc. | PRRSV minor protein-containing recombinant viral vectors and methods of making and use thereof |
CN108883169A (zh) | 2016-03-23 | 2018-11-23 | 英特维特国际股份有限公司 | 针对pcv2和prrs病毒感染的皮内应用疫苗 |
US10279031B2 (en) | 2016-05-11 | 2019-05-07 | Phibro Animal Health Corporation | Composition comprising antigens and a mucosal adjuvant and a method for using |
CN114404439B (zh) * | 2022-02-11 | 2023-07-11 | 山东农业大学 | 抑制不同类型猪繁殖与呼吸综合症病毒感染的阻断剂 |
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US5213795A (en) * | 1990-10-24 | 1993-05-25 | Oxford | Encephalomyocarditis virus vaccine |
CA2103460C (en) * | 1991-06-06 | 2000-09-26 | Gert Wensvoort | Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits |
US6042830A (en) * | 1992-08-05 | 2000-03-28 | Boehringer Ingelheim Vetmedica, Inc. | Viral agent associated with mystery swine disease |
US5846805A (en) * | 1991-08-26 | 1998-12-08 | Boehringer Ingelheim Animal Health, Inc. | Culture of swine infertility and respiratory syndrome virus in simian cells |
CA2076744C (en) * | 1991-08-26 | 2000-06-27 | Danny W. Chladek | Viral agent associated with mystery swine disease |
US6982160B2 (en) * | 1991-08-26 | 2006-01-03 | Boehringer Ingelheim Vetmedica, Inc. | Immunogenic compositions that include SIRS virus |
HU217105B (hu) * | 1991-08-26 | 1999-11-29 | Boehringer Ingelheim Vetmedica, Inc, | SIRS-vakcina, és eljárás a betegség diagnosztizálására |
AU2696792A (en) | 1991-09-16 | 1993-04-27 | David A Benfield | Vaccine for mystery swine disease and method for diagnosis thereof |
DE69206631T2 (de) | 1991-10-14 | 1996-05-15 | Akzo Nobel Nv | Impfstoff gegen das Fortpflanzungs- und Atmungssyndrom bei Schweinen (PRRS) und Diagnose. |
FR2686097B1 (fr) * | 1992-01-14 | 1994-12-30 | Rhone Merieux | Preparation d'antigenes et de vaccins de virus de la mystery disease, antigenes et vaccins obtenus pour la prevention de cette maladie. |
TW289731B (no) * | 1992-07-09 | 1996-11-01 | Akzo Nv | |
US5695766A (en) * | 1992-10-30 | 1997-12-09 | Iowa State University Research Foundation | Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome |
US6251397B1 (en) * | 1992-10-30 | 2001-06-26 | Iowa State University Research Foundation, Inc. | Proteins encoded by polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus and immunogenic compositions containing the same |
US6592873B1 (en) * | 1992-10-30 | 2003-07-15 | Iowa State University Research Foundation, Inc. | Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids |
US6773908B1 (en) * | 1992-10-30 | 2004-08-10 | Iowa State University Research Foundation, Inc. | Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV) |
US6380376B1 (en) * | 1992-10-30 | 2002-04-30 | Iowa State University Research Foundation | Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV) |
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CZ289743B6 (cs) * | 1993-02-08 | 2002-03-13 | Bayer Corporation | Izolát viru vepřového reprodukčního a respiračního syndromu PRRSV, způsob kultivace PRRSV, tkáňová kultura, způsob přípravy vakcíny a vakcína obsahující PRRSV izolát |
EP1004670B1 (en) * | 1993-04-27 | 2012-04-11 | Innogenetics N.V. | Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents |
ES2074950B1 (es) | 1993-09-17 | 1996-03-16 | Iberica Cyanamid | Vacuna para la prevencion de la enfermedad reproductiva y respiratoria de la cerda. |
EP0659885A1 (en) * | 1993-12-21 | 1995-06-28 | Akzo Nobel N.V. | Vaccine against viruses associated with antibody-dependent-enhancement of viral infectivity |
DE4407489A1 (de) * | 1994-03-07 | 1995-09-14 | Bayer Ag | Vakzine zur Prävention von Respirations- und Reproduktionserkrankungen des Schweines |
DE69522984T2 (de) * | 1994-04-11 | 2002-04-25 | Akzo Nobel Nv | Europäische Vakzinstämme des Fortplanzungs-Atmungs-Syndromsvirus des Schweins |
GB2289279B (en) * | 1994-05-13 | 1998-09-16 | Iberica Cyanamid | Diagnostic kits and vaccines containing recombinant PRRSV proteins |
ATE329616T1 (de) | 1994-08-05 | 2006-07-15 | Univ Minnesota | Virale nukleotidsequenz vr-2332 und nutzungsverfahren |
EP0732340B1 (en) * | 1995-03-14 | 2004-06-09 | Akzo Nobel N.V. | Expression of porcine reproductive respiratory syndrome virus polypeptides in the same cell |
ES2102971B1 (es) * | 1996-01-25 | 1998-03-01 | Hipra Lab Sa | Nueva cepa atenuada del virus causante del sindrome respiratorio y reproductivo porcino (prrs), las vacunas y medios de diagnostico obtenibles con la misma y los procedimientos para su obtencion. |
US6015663A (en) * | 1996-03-01 | 2000-01-18 | The United States Of America As Represented By The Secretary Of Agriculture | Restriction enzyme screen for differentiating porcine reproductive and respiratory syndrome virus strains |
US5866401A (en) * | 1996-03-01 | 1999-02-02 | Schering Corporation | Porcine reproductive and respiratory syndrome vaccine |
US6514731B1 (en) * | 1996-05-24 | 2003-02-04 | Chiron Corporation | Methods for the preparation of hepatitis C virus multiple copy epitope fusion antigens |
US5976537A (en) * | 1996-07-02 | 1999-11-02 | The United States Of America As Represented By The Secretary Of Agriculture | Porcine reproductive and respiratory syndrome vaccine |
ES2157522T3 (es) * | 1996-10-09 | 2001-08-16 | Akzo Nobel Nv | Cepas de vacunas europeas del virus del sindrome respiratorio reproductor porcino (prrsv). |
CZ297371B6 (cs) * | 1997-05-06 | 2006-11-15 | Boehringer Ingelheim Vetmedica Gmbh | Peptid mající 5 az 15 aminokyselinových zbytku vyvolávající tvorbu protilátek, protilátka reaktivnís tímto peptidem a diagnostická testovací souprava |
GB9820525D0 (en) * | 1998-09-21 | 1998-11-11 | Allergy Therapeutics Ltd | Formulation |
EP1170367A1 (en) | 2000-06-27 | 2002-01-09 | Bayer Ag | BVDV virus-like particles |
US20060165723A1 (en) | 2004-09-03 | 2006-07-27 | Consejo Superior De Investigaciones Cientificas | Nucleic acid sequences encoding proteins capable of associating into a virus-like particle |
-
1998
- 1998-02-06 US US09/019,793 patent/US6380376B1/en not_active Expired - Fee Related
-
1999
- 1999-02-08 JP JP2000530103A patent/JP2002504317A/ja active Pending
- 1999-02-08 WO PCT/US1999/002630 patent/WO1999039582A1/en active IP Right Grant
- 1999-02-08 EP EP99905840A patent/EP1047301B1/en not_active Expired - Lifetime
- 1999-02-08 ES ES99905840T patent/ES2294834T3/es not_active Expired - Lifetime
- 1999-02-08 KR KR1020007008605A patent/KR100696339B1/ko not_active IP Right Cessation
- 1999-02-08 BR BR9908615-8A patent/BR9908615A/pt not_active IP Right Cessation
- 1999-02-08 AU AU25908/99A patent/AU743212B2/en not_active Ceased
- 1999-02-08 KR KR1020067002766A patent/KR100711656B1/ko not_active IP Right Cessation
- 1999-02-08 DE DE69936977T patent/DE69936977T2/de not_active Expired - Lifetime
- 1999-02-08 AT AT99905840T patent/ATE371373T1/de not_active IP Right Cessation
- 1999-02-08 CA CA2751655A patent/CA2751655C/en not_active Expired - Fee Related
- 1999-02-08 CA CA2320359A patent/CA2320359C/en not_active Expired - Fee Related
-
2000
- 2000-07-07 NO NO20003526A patent/NO329875B1/no not_active IP Right Cessation
-
2001
- 2001-05-02 HK HK01103101A patent/HK1032511A1/xx not_active IP Right Cessation
-
2002
- 2002-03-25 US US10/104,019 patent/US7264802B2/en not_active Expired - Fee Related
-
2007
- 2007-05-24 US US11/802,769 patent/US20080286276A1/en not_active Abandoned
-
2010
- 2010-11-16 JP JP2010256079A patent/JP2011103883A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US20080286276A1 (en) | 2008-11-20 |
BR9908615A (pt) | 2001-10-02 |
KR100711656B1 (ko) | 2007-04-27 |
AU2590899A (en) | 1999-08-23 |
HK1032511A1 (en) | 2001-07-27 |
JP2002504317A (ja) | 2002-02-12 |
CA2320359C (en) | 2013-02-05 |
US20020168379A1 (en) | 2002-11-14 |
EP1047301A4 (en) | 2002-01-02 |
EP1047301A1 (en) | 2000-11-02 |
JP2011103883A (ja) | 2011-06-02 |
CA2751655A1 (en) | 1999-08-12 |
US7264802B2 (en) | 2007-09-04 |
CA2751655C (en) | 2014-04-22 |
US6380376B1 (en) | 2002-04-30 |
KR100696339B1 (ko) | 2007-03-20 |
DE69936977T2 (de) | 2008-05-29 |
NO20003526L (no) | 2000-09-26 |
ATE371373T1 (de) | 2007-09-15 |
DE69936977D1 (de) | 2007-10-11 |
WO1999039582A1 (en) | 1999-08-12 |
KR20060017675A (ko) | 2006-02-24 |
ES2294834T3 (es) | 2008-04-01 |
NO20003526D0 (no) | 2000-07-07 |
AU743212B2 (en) | 2002-01-24 |
US20030138442A9 (en) | 2003-07-24 |
KR20010082511A (ko) | 2001-08-30 |
EP1047301B1 (en) | 2007-08-29 |
CA2320359A1 (en) | 1999-08-12 |
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