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AR063621A1 - Matriz polimerica insoluble en agua para la administracion de farmacos - Google Patents

Matriz polimerica insoluble en agua para la administracion de farmacos

Info

Publication number
AR063621A1
AR063621A1 ARP070104980A ARP070104980A AR063621A1 AR 063621 A1 AR063621 A1 AR 063621A1 AR P070104980 A ARP070104980 A AR P070104980A AR P070104980 A ARP070104980 A AR P070104980A AR 063621 A1 AR063621 A1 AR 063621A1
Authority
AR
Argentina
Prior art keywords
water insoluble
pharmacos
administration
polymeric matrix
polymer matrix
Prior art date
Application number
ARP070104980A
Other languages
English (en)
Original Assignee
Alcon Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Res Ltd filed Critical Alcon Res Ltd
Publication of AR063621A1 publication Critical patent/AR063621A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

Composición farmacéutica que comprende (a) una matriz polimérica insoluble en agua bioerosionable que comprende un polímero poliéster, donde la matriz polimérica tiene un punto de fusión de menos de 60°C y (b) un agente activo disperso en la matriz polimérica, donde la composición se formula para liberar en forma controlable el agente activo durante un período de tiempo predeterminado a un sitio blanco. Métodos de tratamiento de una enfermedad o afección con las composiciones descriptas.
ARP070104980A 2006-11-09 2007-11-08 Matriz polimerica insoluble en agua para la administracion de farmacos AR063621A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85800406P 2006-11-09 2006-11-09

Publications (1)

Publication Number Publication Date
AR063621A1 true AR063621A1 (es) 2009-02-04

Family

ID=39468600

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP070104980A AR063621A1 (es) 2006-11-09 2007-11-08 Matriz polimerica insoluble en agua para la administracion de farmacos

Country Status (16)

Country Link
US (1) US8632809B2 (es)
EP (2) EP2409687B1 (es)
JP (2) JP5411703B2 (es)
KR (2) KR20090082447A (es)
CN (1) CN101553206B (es)
AR (1) AR063621A1 (es)
AU (1) AU2007325409B2 (es)
BR (1) BRPI0718696A2 (es)
CA (1) CA2668814A1 (es)
ES (2) ES2477993T3 (es)
HK (1) HK1132173A1 (es)
MX (1) MX2009004856A (es)
PL (1) PL2091514T3 (es)
TW (1) TWI409081B (es)
WO (1) WO2008067127A2 (es)
ZA (1) ZA200902587B (es)

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Also Published As

Publication number Publication date
WO2008067127A3 (en) 2008-10-09
TW200826963A (en) 2008-07-01
KR20140032505A (ko) 2014-03-14
EP2091514B1 (en) 2013-06-05
AU2007325409A1 (en) 2008-06-05
JP2013129679A (ja) 2013-07-04
TWI409081B (zh) 2013-09-21
CN101553206A (zh) 2009-10-07
US8632809B2 (en) 2014-01-21
WO2008067127A2 (en) 2008-06-05
MX2009004856A (es) 2009-06-05
EP2091514A2 (en) 2009-08-26
EP2409687A1 (en) 2012-01-25
EP2409687B1 (en) 2014-06-11
US20080113027A1 (en) 2008-05-15
JP5411703B2 (ja) 2014-02-12
ZA200902587B (en) 2010-06-30
HK1132173A1 (en) 2010-02-19
KR20090082447A (ko) 2009-07-30
ES2477993T3 (es) 2014-07-18
CN101553206B (zh) 2012-11-21
BRPI0718696A2 (pt) 2013-12-31
CA2668814A1 (en) 2008-06-05
AU2007325409B2 (en) 2013-03-28
ES2421206T3 (es) 2013-08-29
JP2010509361A (ja) 2010-03-25
PL2091514T3 (pl) 2014-03-31

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