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CL2008001509A1 - Composicion farmaceutica de liberacion prolongada que comprende micro-particulas con una matriz que comprende un polimero polilactido-co-glicolido lineal y uno ramificado y pamoato de pasireotida; proceso de elaboracion; micro-particulas; kit; uso para tratar una enfermedad asociada con un exceso de secrecion de gh y/o igf-1. - Google Patents

Composicion farmaceutica de liberacion prolongada que comprende micro-particulas con una matriz que comprende un polimero polilactido-co-glicolido lineal y uno ramificado y pamoato de pasireotida; proceso de elaboracion; micro-particulas; kit; uso para tratar una enfermedad asociada con un exceso de secrecion de gh y/o igf-1.

Info

Publication number
CL2008001509A1
CL2008001509A1 CL2008001509A CL2008001509A CL2008001509A1 CL 2008001509 A1 CL2008001509 A1 CL 2008001509A1 CL 2008001509 A CL2008001509 A CL 2008001509A CL 2008001509 A CL2008001509 A CL 2008001509A CL 2008001509 A1 CL2008001509 A1 CL 2008001509A1
Authority
CL
Chile
Prior art keywords
igf
microparticles
kit
micro
particles
Prior art date
Application number
CL2008001509A
Other languages
English (en)
Inventor
Olivier Lambert
Marc Riemenschnitter
Vitomir Vucenovic
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38222465&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2008001509(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CL2008001509A1 publication Critical patent/CL2008001509A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/31Somatostatins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A61P5/04Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)

Abstract

Composición farmacéutica para liberación prolongada que comprende micro-partículas con una matriz polimérica que comprende uno o más polímeros biodegradables y pamoato de pasireotida; proceso de elaboración; micro-partículas; kit; y uso en el tratamiento de una enfermedad asociada a un exceso de secreción de gh y/o igf-1.
CL2008001509A 2007-05-24 2008-05-23 Composicion farmaceutica de liberacion prolongada que comprende micro-particulas con una matriz que comprende un polimero polilactido-co-glicolido lineal y uno ramificado y pamoato de pasireotida; proceso de elaboracion; micro-particulas; kit; uso para tratar una enfermedad asociada con un exceso de secrecion de gh y/o igf-1. CL2008001509A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07108796 2007-05-24

Publications (1)

Publication Number Publication Date
CL2008001509A1 true CL2008001509A1 (es) 2009-05-08

Family

ID=38222465

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2008001509A CL2008001509A1 (es) 2007-05-24 2008-05-23 Composicion farmaceutica de liberacion prolongada que comprende micro-particulas con una matriz que comprende un polimero polilactido-co-glicolido lineal y uno ramificado y pamoato de pasireotida; proceso de elaboracion; micro-particulas; kit; uso para tratar una enfermedad asociada con un exceso de secrecion de gh y/o igf-1.

Country Status (42)

Country Link
US (2) US20100178344A1 (es)
EP (2) EP2164473B1 (es)
JP (1) JP5507447B2 (es)
KR (2) KR20100017904A (es)
CN (1) CN101677965B (es)
AR (1) AR066677A1 (es)
AU (1) AU2008252931B2 (es)
BR (1) BRPI0811904A2 (es)
CA (1) CA2683935C (es)
CL (1) CL2008001509A1 (es)
CO (1) CO6241097A2 (es)
CR (1) CR11078A (es)
CU (1) CU24028B1 (es)
DK (1) DK2164473T3 (es)
DO (1) DOP2009000262A (es)
EA (1) EA018203B1 (es)
EC (1) ECSP099793A (es)
ES (1) ES2761227T3 (es)
GE (1) GEP20125582B (es)
GT (1) GT200900302A (es)
HN (1) HN2009003296A (es)
HU (1) HUE046490T2 (es)
IL (1) IL201571B (es)
MA (1) MA31445B1 (es)
ME (1) ME00955B (es)
MX (1) MX2009012536A (es)
MY (1) MY148915A (es)
NI (1) NI200900207A (es)
NZ (1) NZ580589A (es)
PA (1) PA8781501A1 (es)
PE (1) PE20090387A1 (es)
PL (1) PL2164473T3 (es)
PT (1) PT2164473T (es)
SI (1) SI2164473T1 (es)
SM (1) SMP200900099B (es)
SV (1) SV2009003421A (es)
TN (1) TN2009000447A1 (es)
TW (1) TWI412373B (es)
UA (1) UA97396C2 (es)
UY (1) UY31103A1 (es)
WO (1) WO2008142153A1 (es)
ZA (1) ZA200907168B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR057181A1 (es) * 2005-11-30 2007-11-21 Astra Ab Nueva forma de dosificacion de combinacion
WO2012083026A1 (en) * 2010-12-15 2012-06-21 Evonik Degussa Corporation Branched polyol polyesters, blends and pharmaceutical formulations comprising same
HUE046004T2 (hu) 2011-04-25 2020-01-28 Shan Dong Luye Pharm Co Ltd Risperidon nyújtott hatóanyagleadású mikroszféra készítmény
TWI562991B (en) * 2012-04-23 2016-12-21 Otsuka Pharma Co Ltd Dihydrate of benzothiophene compound or of a salt thereof, and process for producing the same
ES2834318T3 (es) * 2012-05-25 2021-06-17 Camurus Ab Formulaciones de agonistas de receptores de la somatostatina
US10821200B2 (en) 2016-12-05 2020-11-03 Hyalo Technologies, LLC Method of sterilization of microparticles
EP3339372A1 (en) * 2016-12-22 2018-06-27 Solvay SA Glycolic acid polymer composition
CN110870853B (zh) * 2018-08-29 2020-12-11 深圳翰宇药业股份有限公司 缓释帕瑞肽微球及其制备方法
MX2021006601A (es) * 2018-12-04 2021-07-07 Vanda Pharmaceuticals Inc Administracion de iloperidona de liberacion lenta.

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US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
CH656884A5 (de) 1983-08-26 1986-07-31 Sandoz Ag Polyolester, deren herstellung und verwendung.
CA2316052C (en) * 1989-07-07 2008-09-02 David Bodmer Sustained release formulations of water soluble peptides
FI106926B (fi) * 1989-07-07 2001-05-15 Novartis Ag Menetelmä pitkäaikaisesti vapautuvan koostumuksen muodostamiseksi
US5538739A (en) 1989-07-07 1996-07-23 Sandoz Ltd. Sustained release formulations of water soluble peptides
PH30995A (en) 1989-07-07 1997-12-23 Novartis Inc Sustained release formulations of water soluble peptides.
IE960308A1 (en) * 1996-04-23 1997-11-05 Kinerton Ltd Sustained release ionic conjugate
AU5678398A (en) * 1997-01-29 1998-08-18 Takeda Chemical Industries Ltd. Sustained-release microspheres, their production and use
EP1240896A3 (en) 1998-07-23 2003-03-26 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Encapsulation of water soluble peptides
GB0018891D0 (en) 2000-08-01 2000-09-20 Novartis Ag Organic compounds
GB0326602D0 (en) * 2003-11-14 2003-12-17 Novartis Ag Organic compounds
MY158342A (en) * 2003-11-14 2016-09-30 Novartis Ag Pharmaceutical composition
EP1689429A1 (en) * 2003-11-25 2006-08-16 Novartis AG Biomarkers for the efficacy of somatostatin analogue treatment

Also Published As

Publication number Publication date
EP3666263A1 (en) 2020-06-17
CA2683935A1 (en) 2008-11-27
MX2009012536A (es) 2009-12-03
US20100178344A1 (en) 2010-07-15
UA97396C2 (ru) 2012-02-10
UY31103A1 (es) 2009-01-05
CA2683935C (en) 2016-07-19
IL201571A0 (en) 2010-05-31
ZA200907168B (en) 2010-07-28
SMP200900099B (it) 2010-11-12
CU20090200A7 (es) 2011-09-21
CO6241097A2 (es) 2011-01-20
NZ580589A (en) 2011-12-22
CN101677965A (zh) 2010-03-24
JP2010527971A (ja) 2010-08-19
SMAP200900099A (it) 2010-01-19
PA8781501A1 (es) 2008-12-18
HN2009003296A (es) 2014-02-10
CU24028B1 (es) 2014-10-02
IL201571B (en) 2018-11-29
PT2164473T (pt) 2019-12-11
NI200900207A (es) 2010-09-07
DOP2009000262A (es) 2010-10-15
GEP20125582B (en) 2012-07-25
ES2761227T3 (es) 2020-05-19
MY148915A (en) 2013-06-14
AR066677A1 (es) 2009-09-02
ME00955B (me) 2012-06-20
SV2009003421A (es) 2010-05-21
JP5507447B2 (ja) 2014-05-28
KR20160002937A (ko) 2016-01-08
ECSP099793A (es) 2010-01-29
HUE046490T2 (hu) 2020-03-30
BRPI0811904A2 (pt) 2014-11-18
CR11078A (es) 2009-12-04
EP2164473B1 (en) 2019-09-11
DK2164473T3 (da) 2019-12-16
MA31445B1 (fr) 2010-06-01
EA018203B1 (ru) 2013-06-28
US20130129798A1 (en) 2013-05-23
US9351923B2 (en) 2016-05-31
TN2009000447A1 (en) 2011-03-31
TWI412373B (zh) 2013-10-21
SI2164473T1 (sl) 2020-02-28
KR20100017904A (ko) 2010-02-16
EP2164473A1 (en) 2010-03-24
PL2164473T3 (pl) 2020-07-27
GT200900302A (es) 2011-07-01
CN101677965B (zh) 2015-09-09
KR101930588B1 (ko) 2018-12-18
AU2008252931A1 (en) 2008-11-27
EA200901523A1 (ru) 2010-04-30
AU2008252931B2 (en) 2011-09-01
PE20090387A1 (es) 2009-04-28
WO2008142153A1 (en) 2008-11-27
TW200906437A (en) 2009-02-16

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